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The map label for this gene is sglT [H]

Identifier: 193212888

GI number: 193212888

Start: 1351723

End: 1353483

Strand: Direct

Name: sglT [H]

Synonym: Cpar_1236

Alternate gene names: 193212888

Gene position: 1351723-1353483 (Clockwise)

Preceding gene: 193212887

Following gene: 193212889

Centisome position: 59.05

GC content: 59.8

Gene sequence:

>1761_bases
ATGGCACAACTCACCCCACTGGACATCTCATTCATTGCGGGTTACCTGCTGTTAACCCTGCTGGTCGGCCTGTTCTTTTC
AAGGCGGGCATCCGAAAACGTTGGCGAGTTCTTCCTTTCGGGACGCAAGCTACCGTGGTGGATCGCAGGTACCGGCATGG
TTGCCACAACGTTCGCCGCCGACACACCGCTCGCCGTGGCGGGGTTTGTTGCCAAAAACGGCATCGCGGGGAACTGGGTG
TGGTGGACGTTCGTGTCGGGTGGAATGCTTACGGTGTTCTTTTTCGCCCGGCTCTGGCGACGGGCAAACATTCTAACCGA
CCTCGAATTCATCGAGCTGCGCTACAGCGGCAAGGCTGCGAGCTTTCTGCGCGGCTTCAAGGCGATTTATTTCGGCCTCT
TCATCAACGCGGTGATCATCGGGTGGGTGAACCTGGCCATGTTCAAAATCATCAAGATCATGATCCCCGGCCTAGACCCG
CAGCTCACCATCGTGGGGCTCGTGATTTTCACGGCGATCTACTCCGGCATGTCTGGCCTGTGGGGCGTTTCAATCACCGA
TGCCGTGCAGTTCATCATCGCGATGGGTGGTTGCATCGTCCTCGCAGTGCTGGCGGTCAACTCGCCGCAGGTTACGGCGG
CTGGCGGCCTGAAAGAGGCCCTGCCTGGCTGGATGTTCGACTTCTTCCCGTCGTTCTCTTCGACCGTCAACACATCGGCG
ACCGGAGCCTACGCCCTGCCCTTCACCGCCTTTGCTGCTATGGCGTTCGTGCAGTGGTGGTCGTCGTGGTATCCGGGCGC
GGAGCCGGGCGGCGGCGGCTACATCGCCCAGCGCATGATGAGCGCCAAGGACGAAAAAAACTCGCTGCTGGCGACGCTCT
GGTTCACTATTGCGCACTACTGCGTACGCCCGTGGCCATGGATCGTCGTCGGCCTGGCGAGCCTCGTGATGTTCCCTCAC
CTGCCCGCCGGTCAGAAGGAGGACGGCTTCGTGTATGTCATGAACGCCGTGCTGCCCGCCGGACTGAAGGGCCTGCTCAT
CGCAGCCTTCATGGCGGCCTACATGTCAACGCTCTCGACCCACCTGAACTGGGGCACGAGCTACCTCATCAACGACCTTT
ACAAGCGCTTCGTCAAGCCGGAGGCTGAACAGAACCACTACGTGCTGATGTCGCGGATCGTCACGGCGATCACGGCGATC
TTCGCCCTTTACATCACGTTCTACGTGCTGGAGACCATCACCGGCGCCTGGGAGTTCATCATCCAGTGCGGCGCGGGCAC
AGGCTTCGTGCTGATCATGCGCTGGTTCTGGTGGCGGCTCAACGCCTGGTCGGAGATCACCTCGATGGTCGCGCCGATCG
TTGCATACACCTGGATCAGCCAGTTCACCACGATCGTGTTCCCCGAGTCAATCTACATCATCGTGCTCTTCACGATTGCC
GTAACCCTCGCCGTCACCTGGCTCACCAAACCAACTGACAGATCAACGTTGCACGCCTTCTACCGCACCACGAGGGTTGG
CGGAGCGCTGTGGAAACCGGTGGCCGACGAACTTCCTGACGTACAAGGCGACACCGGCTTCCCGGCCCTTTTTGCCAACT
GGTTTTTCGGCATCGTGCTGGTTTACGCCACACTGTTCGGAACCGGCAAACTGATCTTTGGCGAACCGCTGGCTGCCGCG
CTCTACTACGCCGCCGGAGCATTGGCTGGCGTAATGATCTACCGCGACCTGTCGAAGAGAAACTGGAAAACCTTCGATTA
A

Upstream 100 bases:

>100_bases
GAGTAATCACGGTGGATTTGATGGGCAAAATAGACCCAATGGACAACATGGATAACCGCCCACCACATTCCTGAAAAGGC
ACCAAACCCAACACACGACC

Downstream 100 bases:

>100_bases
CAATGACCTCGCGCCGCAAACTCATCCTCGCCTCGCAATCGCCGCGACGTCGGGAATTGCTCGCCATGACGGGAATTCCG
TTCGAAACCGCCTCGGTCGA

Product: Na+/solute symporter

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 586; Mature: 585

Protein sequence:

>586_residues
MAQLTPLDISFIAGYLLLTLLVGLFFSRRASENVGEFFLSGRKLPWWIAGTGMVATTFAADTPLAVAGFVAKNGIAGNWV
WWTFVSGGMLTVFFFARLWRRANILTDLEFIELRYSGKAASFLRGFKAIYFGLFINAVIIGWVNLAMFKIIKIMIPGLDP
QLTIVGLVIFTAIYSGMSGLWGVSITDAVQFIIAMGGCIVLAVLAVNSPQVTAAGGLKEALPGWMFDFFPSFSSTVNTSA
TGAYALPFTAFAAMAFVQWWSSWYPGAEPGGGGYIAQRMMSAKDEKNSLLATLWFTIAHYCVRPWPWIVVGLASLVMFPH
LPAGQKEDGFVYVMNAVLPAGLKGLLIAAFMAAYMSTLSTHLNWGTSYLINDLYKRFVKPEAEQNHYVLMSRIVTAITAI
FALYITFYVLETITGAWEFIIQCGAGTGFVLIMRWFWWRLNAWSEITSMVAPIVAYTWISQFTTIVFPESIYIIVLFTIA
VTLAVTWLTKPTDRSTLHAFYRTTRVGGALWKPVADELPDVQGDTGFPALFANWFFGIVLVYATLFGTGKLIFGEPLAAA
LYYAAGALAGVMIYRDLSKRNWKTFD

Sequences:

>Translated_586_residues
MAQLTPLDISFIAGYLLLTLLVGLFFSRRASENVGEFFLSGRKLPWWIAGTGMVATTFAADTPLAVAGFVAKNGIAGNWV
WWTFVSGGMLTVFFFARLWRRANILTDLEFIELRYSGKAASFLRGFKAIYFGLFINAVIIGWVNLAMFKIIKIMIPGLDP
QLTIVGLVIFTAIYSGMSGLWGVSITDAVQFIIAMGGCIVLAVLAVNSPQVTAAGGLKEALPGWMFDFFPSFSSTVNTSA
TGAYALPFTAFAAMAFVQWWSSWYPGAEPGGGGYIAQRMMSAKDEKNSLLATLWFTIAHYCVRPWPWIVVGLASLVMFPH
LPAGQKEDGFVYVMNAVLPAGLKGLLIAAFMAAYMSTLSTHLNWGTSYLINDLYKRFVKPEAEQNHYVLMSRIVTAITAI
FALYITFYVLETITGAWEFIIQCGAGTGFVLIMRWFWWRLNAWSEITSMVAPIVAYTWISQFTTIVFPESIYIIVLFTIA
VTLAVTWLTKPTDRSTLHAFYRTTRVGGALWKPVADELPDVQGDTGFPALFANWFFGIVLVYATLFGTGKLIFGEPLAAA
LYYAAGALAGVMIYRDLSKRNWKTFD
>Mature_585_residues
AQLTPLDISFIAGYLLLTLLVGLFFSRRASENVGEFFLSGRKLPWWIAGTGMVATTFAADTPLAVAGFVAKNGIAGNWVW
WTFVSGGMLTVFFFARLWRRANILTDLEFIELRYSGKAASFLRGFKAIYFGLFINAVIIGWVNLAMFKIIKIMIPGLDPQ
LTIVGLVIFTAIYSGMSGLWGVSITDAVQFIIAMGGCIVLAVLAVNSPQVTAAGGLKEALPGWMFDFFPSFSSTVNTSAT
GAYALPFTAFAAMAFVQWWSSWYPGAEPGGGGYIAQRMMSAKDEKNSLLATLWFTIAHYCVRPWPWIVVGLASLVMFPHL
PAGQKEDGFVYVMNAVLPAGLKGLLIAAFMAAYMSTLSTHLNWGTSYLINDLYKRFVKPEAEQNHYVLMSRIVTAITAIF
ALYITFYVLETITGAWEFIIQCGAGTGFVLIMRWFWWRLNAWSEITSMVAPIVAYTWISQFTTIVFPESIYIIVLFTIAV
TLAVTWLTKPTDRSTLHAFYRTTRVGGALWKPVADELPDVQGDTGFPALFANWFFGIVLVYATLFGTGKLIFGEPLAAAL
YYAAGALAGVMIYRDLSKRNWKTFD

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI14140236, Length=414, Percent_Identity=24.8792270531401, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI109659836, Length=430, Percent_Identity=24.8837209302326, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI17941285, Length=474, Percent_Identity=23.8396624472574, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4507033, Length=438, Percent_Identity=24.2009132420091, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4507031, Length=428, Percent_Identity=22.6635514018692, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI109659839, Length=446, Percent_Identity=23.9910313901345, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 64791; Mature: 64659

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLTPLDISFIAGYLLLTLLVGLFFSRRASENVGEFFLSGRKLPWWIAGTGMVATTFAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCHHHHHCCC
DTPLAVAGFVAKNGIAGNWVWWTFVSGGMLTVFFFARLWRRANILTDLEFIELRYSGKAA
CCCHHHHHHHHHCCCCCCCCEEEHHCCCHHHHHHHHHHHHHHHHHHCHHHHEEEECCCHH
SFLRGFKAIYFGLFINAVIIGWVNLAMFKIIKIMIPGLDPQLTIVGLVIFTAIYSGMSGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
WGVSITDAVQFIIAMGGCIVLAVLAVNSPQVTAAGGLKEALPGWMFDFFPSFSSTVNTSA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHCCHHHHHHHCCCCCCCCCCC
TGAYALPFTAFAAMAFVQWWSSWYPGAEPGGGGYIAQRMMSAKDEKNSLLATLWFTIAHY
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
CVRPWPWIVVGLASLVMFPHLPAGQKEDGFVYVMNAVLPAGLKGLLIAAFMAAYMSTLST
HHCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHH
HLNWGTSYLINDLYKRFVKPEAEQNHYVLMSRIVTAITAIFALYITFYVLETITGAWEFI
HHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQCGAGTGFVLIMRWFWWRLNAWSEITSMVAPIVAYTWISQFTTIVFPESIYIIVLFTIA
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VTLAVTWLTKPTDRSTLHAFYRTTRVGGALWKPVADELPDVQGDTGFPALFANWFFGIVL
HHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
VYATLFGTGKLIFGEPLAAALYYAAGALAGVMIYRDLSKRNWKTFD
HHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AQLTPLDISFIAGYLLLTLLVGLFFSRRASENVGEFFLSGRKLPWWIAGTGMVATTFAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCEEEECCCHHHHHCCC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HHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]