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The map label for this gene is mcpCc [H]

Identifier: 190895009

GI number: 190895009

Start: 729486

End: 731363

Strand: Reverse

Name: mcpCc [H]

Synonym: RHECIAT_PC0000675

Alternate gene names: 190895009

Gene position: 731363-729486 (Counterclockwise)

Preceding gene: 190895010

Following gene: 190895008

Centisome position: 67.0

GC content: 58.95

Gene sequence:

>1878_bases
ATGAAACGCCCGAGCATCAAGCAAGCACTCATCCTAAAGCTATCCATCATCAGCATGTTCATACTTGGTCTGTCCTACGT
CTCGCTGGACACCATTTCCTCGCTTCGCGCAAATGCTGAGCAGGTCGGTACCTTCTGGGTGCATCGGCTGGTGACAGCGC
GTGAGATCAAAGCAAACTTTCTTGATCTGAAACTTGCCCACGCCCGGTACTTGCTCGAAGACACCGCGGAGAACGACAAA
ACCGAAAAGCAAGCGATCGAAGCTGCAGCCGCTGGGCTCGAGACGGTCGTCGGCGAATACGAAAAGGGCGTGCGCACGGA
GCGCGGGCGCCAGTTGATCAATCAGATAAAGCCGGAAATCGACAAATATCGCGCGTTGGCGGAGCAAATGATTGCGCTCG
AAGATAGCGGCAAGACAGCTGAGGCAGTCCGGCTGTTCAAGGAGAAGATGGAGCCGCAGGCCGAGTTGGTGAACAATGGG
GTAGCGGATCTGGTGGCATTCATTCTCAGCCAGACCGAAGGCTTCGTGGCGGCAAGTGATGCTTCCGCGAAATCCGCTTT
CATGCTGACTGCTGCGATCGCCTCGCTGGCCTTGCTCGTGGCTATCGCGGGTATCGTCTTTGGGATTTCCGGCATTGCCA
ATCCGATCCGCAATACGGCGTCCGCCATGAAACGGTTGTCGGCTGGAGATCTCGACAGCGATATTCCTTATGCCGGCCGT
GCGGACGAAATCGGTGAAATGGCCGGCGCAGTTGAAGTGTTTCGCCAGAATGCTCTCAACGTTGTCAGGCTTGAGAAGGA
AGCTGCCGAATCCCGCAGTGAGAGCGAGGCGGCGCGCGCCGCAGCCCAGCAGCGTGCCGAACGCGAAGCCGAGCAGCTGC
GCTTTGCAACGACTACCTTGGGCGGAGGTCTCCGGCGCCTTGCCGCGGGCGACATATCCTTCCAGCTCTCGGAGCGATTT
GCCGCTGAATACGAAGCATTGCGCGACGATTTCAATACTTCGCTGCGGCAATTGGGCGCGACGATCGGCGCCGTGCTTCA
GACGGTGCACAGCATAGACAATGGCACCGGTGAAATAGCATCCGGTGCCCAGGACCTATCGAAGCGCACGGAACAACAGG
CCGCTTCCCTCGAGGAGACCGCCGCCGCGTTGGACGAGATTACCTCGAATGTCGCGATGGCGACGAAACGCACCGAGGAG
GCGCGCAATATCTCTGTGGAAGCCAATGTCAGCGCCCAGCGCTCGGCAAACATCGTGTCGGAGGCGGAGCAGGCCATGCG
ACGCATCGAGGACAGTTCGCAGCAGATTTCGAATATCATTGGCGTCATCGACGAAATTGCTTTCCAGACGAACCTTCTGG
CGCTCAACGCCGGTGTCGAGGCAGCGCGCGCAGGTGAGGCAGGAAAGGGTTTTGCGGTCGTCGCACAGGAAGTCCGCGAG
CTCGCCCAGCGTGCCGCGCAGGCGGCCAAGGAAATCAAAGGTCTCATTCAGAAGTCGTCGACCGAAGTCGAGCACGGGGT
CAAACTTGTTCTCGAAACCGGGACGTCACTGAAATCGATCGGCGAACGCGTTGCCGAAATTAATCGAGCCATGGAGGCGA
TCGCCACCTCGGCGCGCGAGCAGGCGACCGGGCTTTCCGAAATCAACACCGCCATCAATCACATGGATCAGGCAACTCAG
CAGAATGCGGCGATGGTCGAGCAGTCCACGGCCGCCGCCTCTTCACTAGCCTCAGAAGCAAGCCGCCTGCGCGAACTGGT
CAATCAGTTCCAGTTGGATGGTGACAGAGGTCCAGCGAATGTCCAGTCCAATACTCGCTCGTTGGAAAGCCGCATGCCGT
CGCAAGTGGTCGCTCTGCGGCCCGCGATGCGAAGGTAA

Upstream 100 bases:

>100_bases
GAAACCCGAACGAATCTCTTGGTTTAGTTAACACTAAATTGTCGAATCCGATGGGAGATTTTGCCTTAACCGGCAGCGAC
CGTCCCAAGAGGAGACCCGC

Downstream 100 bases:

>100_bases
ACTTGCCGCCGTGGTCAGTCTTGTCAGTTTGAAGGGAAGACTCCCTGATGAGAATAATGGCGCCGCAGCTTCAGGCTGTG
CTGCTGTGGACAAAGAGGTT

Product: methyl accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MKRPSIKQALILKLSIISMFILGLSYVSLDTISSLRANAEQVGTFWVHRLVTAREIKANFLDLKLAHARYLLEDTAENDK
TEKQAIEAAAAGLETVVGEYEKGVRTERGRQLINQIKPEIDKYRALAEQMIALEDSGKTAEAVRLFKEKMEPQAELVNNG
VADLVAFILSQTEGFVAASDASAKSAFMLTAAIASLALLVAIAGIVFGISGIANPIRNTASAMKRLSAGDLDSDIPYAGR
ADEIGEMAGAVEVFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTLGGGLRRLAAGDISFQLSERF
AAEYEALRDDFNTSLRQLGATIGAVLQTVHSIDNGTGEIASGAQDLSKRTEQQAASLEETAAALDEITSNVAMATKRTEE
ARNISVEANVSAQRSANIVSEAEQAMRRIEDSSQQISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
LAQRAAQAAKEIKGLIQKSSTEVEHGVKLVLETGTSLKSIGERVAEINRAMEAIATSAREQATGLSEINTAINHMDQATQ
QNAAMVEQSTAAASSLASEASRLRELVNQFQLDGDRGPANVQSNTRSLESRMPSQVVALRPAMRR

Sequences:

>Translated_625_residues
MKRPSIKQALILKLSIISMFILGLSYVSLDTISSLRANAEQVGTFWVHRLVTAREIKANFLDLKLAHARYLLEDTAENDK
TEKQAIEAAAAGLETVVGEYEKGVRTERGRQLINQIKPEIDKYRALAEQMIALEDSGKTAEAVRLFKEKMEPQAELVNNG
VADLVAFILSQTEGFVAASDASAKSAFMLTAAIASLALLVAIAGIVFGISGIANPIRNTASAMKRLSAGDLDSDIPYAGR
ADEIGEMAGAVEVFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTLGGGLRRLAAGDISFQLSERF
AAEYEALRDDFNTSLRQLGATIGAVLQTVHSIDNGTGEIASGAQDLSKRTEQQAASLEETAAALDEITSNVAMATKRTEE
ARNISVEANVSAQRSANIVSEAEQAMRRIEDSSQQISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
LAQRAAQAAKEIKGLIQKSSTEVEHGVKLVLETGTSLKSIGERVAEINRAMEAIATSAREQATGLSEINTAINHMDQATQ
QNAAMVEQSTAAASSLASEASRLRELVNQFQLDGDRGPANVQSNTRSLESRMPSQVVALRPAMRR
>Mature_625_residues
MKRPSIKQALILKLSIISMFILGLSYVSLDTISSLRANAEQVGTFWVHRLVTAREIKANFLDLKLAHARYLLEDTAENDK
TEKQAIEAAAAGLETVVGEYEKGVRTERGRQLINQIKPEIDKYRALAEQMIALEDSGKTAEAVRLFKEKMEPQAELVNNG
VADLVAFILSQTEGFVAASDASAKSAFMLTAAIASLALLVAIAGIVFGISGIANPIRNTASAMKRLSAGDLDSDIPYAGR
ADEIGEMAGAVEVFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTLGGGLRRLAAGDISFQLSERF
AAEYEALRDDFNTSLRQLGATIGAVLQTVHSIDNGTGEIASGAQDLSKRTEQQAASLEETAAALDEITSNVAMATKRTEE
ARNISVEANVSAQRSANIVSEAEQAMRRIEDSSQQISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
LAQRAAQAAKEIKGLIQKSSTEVEHGVKLVLETGTSLKSIGERVAEINRAMEAIATSAREQATGLSEINTAINHMDQATQ
QNAAMVEQSTAAASSLASEASRLRELVNQFQLDGDRGPANVQSNTRSLESRMPSQVVALRPAMRR

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=289, Percent_Identity=43.2525951557093, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1788194, Length=294, Percent_Identity=42.5170068027211, Blast_Score=201, Evalue=2e-52,
Organism=Escherichia coli, GI2367378, Length=289, Percent_Identity=46.0207612456747, Blast_Score=201, Evalue=2e-52,
Organism=Escherichia coli, GI1788195, Length=312, Percent_Identity=41.9871794871795, Blast_Score=198, Evalue=8e-52,
Organism=Escherichia coli, GI1789453, Length=277, Percent_Identity=36.8231046931408, Blast_Score=159, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 67053; Mature: 67053

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPSIKQALILKLSIISMFILGLSYVSLDTISSLRANAEQVGTFWVHRLVTAREIKANF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDLKLAHARYLLEDTAENDKTEKQAIEAAAAGLETVVGEYEKGVRTERGRQLINQIKPEI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DKYRALAEQMIALEDSGKTAEAVRLFKEKMEPQAELVNNGVADLVAFILSQTEGFVAASD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHCCCCEEECC
ASAKSAFMLTAAIASLALLVAIAGIVFGISGIANPIRNTASAMKRLSAGDLDSDIPYAGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
ADEIGEMAGAVEVFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGGLRRLAAGDISFQLSERFAAEYEALRDDFNTSLRQLGATIGAVLQTVHSIDNGTGEIA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
SGAQDLSKRTEQQAASLEETAAALDEITSNVAMATKRTEEARNISVEANVSAQRSANIVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHH
EAEQAMRRIEDSSQQISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHCCCCCCCHHHHHHHHHH
LAQRAAQAAKEIKGLIQKSSTEVEHGVKLVLETGTSLKSIGERVAEINRAMEAIATSARE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QATGLSEINTAINHMDQATQQNAAMVEQSTAAASSLASEASRLRELVNQFQLDGDRGPAN
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VQSNTRSLESRMPSQVVALRPAMRR
CHHHHHHHHHHCCHHHHHHCHHHCC
>Mature Secondary Structure
MKRPSIKQALILKLSIISMFILGLSYVSLDTISSLRANAEQVGTFWVHRLVTAREIKANF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDLKLAHARYLLEDTAENDKTEKQAIEAAAAGLETVVGEYEKGVRTERGRQLINQIKPEI
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DKYRALAEQMIALEDSGKTAEAVRLFKEKMEPQAELVNNGVADLVAFILSQTEGFVAASD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHCCCCEEECC
ASAKSAFMLTAAIASLALLVAIAGIVFGISGIANPIRNTASAMKRLSAGDLDSDIPYAGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
ADEIGEMAGAVEVFRQNALNVVRLEKEAAESRSESEAARAAAQQRAEREAEQLRFATTTL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGGLRRLAAGDISFQLSERFAAEYEALRDDFNTSLRQLGATIGAVLQTVHSIDNGTGEIA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
SGAQDLSKRTEQQAASLEETAAALDEITSNVAMATKRTEEARNISVEANVSAQRSANIVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHH
EAEQAMRRIEDSSQQISNIIGVIDEIAFQTNLLALNAGVEAARAGEAGKGFAVVAQEVRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHCCCCCCCHHHHHHHHHH
LAQRAAQAAKEIKGLIQKSSTEVEHGVKLVLETGTSLKSIGERVAEINRAMEAIATSARE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QATGLSEINTAINHMDQATQQNAAMVEQSTAAASSLASEASRLRELVNQFQLDGDRGPAN
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VQSNTRSLESRMPSQVVALRPAMRR
CHHHHHHHHHHCCHHHHHHCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]