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The map label for this gene is rnc

Identifier: 190571469

GI number: 190571469

Start: 1155223

End: 1155915

Strand: Direct

Name: rnc

Synonym: WPa_1084

Alternate gene names: 190571469

Gene position: 1155223-1155915 (Clockwise)

Preceding gene: 190571468

Following gene: 190571473

Centisome position: 77.93

GC content: 34.78

Gene sequence:

>693_bases
ATGAGAGTTTTGAACGATACAATATCTAAAGTTATTAATTATAAATTTACAGATTATGCAATATTAGAAGAGGCATTAAC
CCACCCAAGCGTAAATAAGAGAAATAGCGAAGACCAGGTTGTAAGCTACGAAAGGCTAGAGTTTTTGGGCGATAGTGTTT
TGAATATGGTTGTGTCTGTTATGCTGTTTAAAATGTTTCCTGAAGAAAAAGAAGGAGCATTGGCAAAAAGAAAAACGGAT
TTAGTTTGTGGCAGTACCATTGCTAATGTTGCTAAAGAAATAGAGTTAGGTAACTTTATTATCATGAATAATAGTGAACG
TTGTAACGGAGGAAAATGTAACTTAAAAAATTTAGAAAATTCGCTTGAAGCACTAATAGGTGCAATTTATATTGACGGCG
GACTTGAGAGTGTTGAGAAATTTATTATCCGACATTGGGAAAAGCTAGCTAAGGACATCCTCGATCCTCCTCAAGATCCT
AAAACTTCACTGCAAGAATGGACTCAGAGAAATAAATTACCTTTACCGAAGTATGAGCTTGTAAAACAAACTGGACCAGC
ACACAATCCTGAATTTACTATATCAGTTTGCATAGAGAGTTATGACAAAGTTTCTGCATGCGCTCCTAGTAAGAAAATTG
CTGAACAAAAAGCTGCTGAGTTGATCCTAGAAAAAATTAAAAAAACGACTTAG

Upstream 100 bases:

>100_bases
TACATTAATTTTGGAAGTTATTGATATTGTTTTAGTAAAGTAGAGCTAACTTTTTAGTGTAGAGGTATGATAGAGAGTGC
TTTTCTATTGAATGATTAAT

Downstream 100 bases:

>100_bases
TTTAATCAAAATAGCTGTTAGCATAAATTTAAAGTAAGCTAAGCTCTTTAGTTCAGCTTACATATTTTTTTATCTCAGCC
AGAATCTTATCAGATTGACT

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MRVLNDTISKVINYKFTDYAILEEALTHPSVNKRNSEDQVVSYERLEFLGDSVLNMVVSVMLFKMFPEEKEGALAKRKTD
LVCGSTIANVAKEIELGNFIIMNNSERCNGGKCNLKNLENSLEALIGAIYIDGGLESVEKFIIRHWEKLAKDILDPPQDP
KTSLQEWTQRNKLPLPKYELVKQTGPAHNPEFTISVCIESYDKVSACAPSKKIAEQKAAELILEKIKKTT

Sequences:

>Translated_230_residues
MRVLNDTISKVINYKFTDYAILEEALTHPSVNKRNSEDQVVSYERLEFLGDSVLNMVVSVMLFKMFPEEKEGALAKRKTD
LVCGSTIANVAKEIELGNFIIMNNSERCNGGKCNLKNLENSLEALIGAIYIDGGLESVEKFIIRHWEKLAKDILDPPQDP
KTSLQEWTQRNKLPLPKYELVKQTGPAHNPEFTISVCIESYDKVSACAPSKKIAEQKAAELILEKIKKTT
>Mature_230_residues
MRVLNDTISKVINYKFTDYAILEEALTHPSVNKRNSEDQVVSYERLEFLGDSVLNMVVSVMLFKMFPEEKEGALAKRKTD
LVCGSTIANVAKEIELGNFIIMNNSERCNGGKCNLKNLENSLEALIGAIYIDGGLESVEKFIIRHWEKLAKDILDPPQDP
KTSLQEWTQRNKLPLPKYELVKQTGPAHNPEFTISVCIESYDKVSACAPSKKIAEQKAAELILEKIKKTT

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain

Homologues:

Organism=Homo sapiens, GI155030236, Length=189, Percent_Identity=32.8042328042328, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI155030234, Length=189, Percent_Identity=32.8042328042328, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1788920, Length=192, Percent_Identity=37.5, Blast_Score=135, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17506883, Length=217, Percent_Identity=29.9539170506912, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193202651, Length=188, Percent_Identity=31.9148936170213, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17137682, Length=223, Percent_Identity=30.4932735426009, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNC_WOLPP (B3CMS0)

Other databases:

- EMBL:   AM999887
- RefSeq:   YP_001975827.1
- EnsemblBacteria:   EBWOLT00000000859
- GeneID:   6384539
- GenomeReviews:   AM999887_GR
- KEGG:   wpi:WPa_1084
- GeneTree:   EBGT00050000030997
- HOGENOM:   HBG744556
- OMA:   ALTHKSF
- ProtClustDB:   PRK00102
- GO:   GO:0005737
- HAMAP:   MF_00104
- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907
- Gene3D:   G3DSA:3.30.160.20
- Gene3D:   G3DSA:1.10.1520.10
- SMART:   SM00358
- SMART:   SM00535
- TIGRFAMs:   TIGR02191

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3; SSF69065 RNase_III

EC number: =3.1.26.3

Molecular weight: Translated: 25906; Mature: 25906

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50137 DS_RBD; PS00517 RNASE_3_1; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLNDTISKVINYKFTDYAILEEALTHPSVNKRNSEDQVVSYERLEFLGDSVLNMVVSV
CCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLFKMFPEEKEGALAKRKTDLVCGSTIANVAKEIELGNFIIMNNSERCNGGKCNLKNLEN
HHHHHCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHH
SLEALIGAIYIDGGLESVEKFIIRHWEKLAKDILDPPQDPKTSLQEWTQRNKLPLPKYEL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHH
VKQTGPAHNPEFTISVCIESYDKVSACAPSKKIAEQKAAELILEKIKKTT
HHHCCCCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVLNDTISKVINYKFTDYAILEEALTHPSVNKRNSEDQVVSYERLEFLGDSVLNMVVSV
CCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MLFKMFPEEKEGALAKRKTDLVCGSTIANVAKEIELGNFIIMNNSERCNGGKCNLKNLEN
HHHHHCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHH
SLEALIGAIYIDGGLESVEKFIIRHWEKLAKDILDPPQDPKTSLQEWTQRNKLPLPKYEL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHH
VKQTGPAHNPEFTISVCIESYDKVSACAPSKKIAEQKAAELILEKIKKTT
HHHCCCCCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA