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The map label for this gene is yaeL [C]

Identifier: 190571425

GI number: 190571425

Start: 1106046

End: 1107161

Strand: Reverse

Name: yaeL [C]

Synonym: WPa_1038

Alternate gene names: 190571425

Gene position: 1107161-1106046 (Counterclockwise)

Preceding gene: 190571427

Following gene: 190571424

Centisome position: 74.68

GC content: 33.78

Gene sequence:

>1116_bases
GTGGAATTAATTTCTCATCAACTTAGCGCTGGAATATATTATTTTTTATCGTTTTCTTTAATAATTTCTATCATAGTATT
CGTGCATGAATGTGGGCATTATATTGTCGCTAAAGCATGCAAGGTTAAAGTTGAATCTTTTTCTATAGGCTTTGGTCCTG
AAATTTTTGGTTTTAACGACAAGTCTGGAACTAGATGGAAATTAAGTGCCTTTCCATTGGGTGGTTACGTTAAAATGTTA
GGGGATACTAATGCAGCAAGCGTTCCTGTTGATCAACAAAAATTAACTGAAGAAGAAAAATTATACTCATTCCATACAAA
ACCTCGATATCAAAAAGCAGCAATAGTTTTTGCAGGGCCTTTTGCAAACATGATATTTACCGTTATAGCCTTCACAATAT
TTTTCAGCGTGGCAGGTTATTATCGTACTCCACCAGTAATTGGTAATGTAATTGAAGAAAGTGCAGCAAAGCAAGCTGGC
CTATTACCAGGTGACACTATTACACAGATCAATGAGTACAAAATAAAATACTTTGAAGATATTTCACGCGTGATAATGTC
CAACCCTGAAACAAGAATAGAAATTAAGTATAGCAGAAATAACGAAGAGTACAGAACTATTCTAACTCCGTTTACAGTTG
AGGATAGAGATGTCTTTGGTAACATAATAGAAAGAAAAACTATAGGAATTACCTCAATTAATATGATAGGGTTAAAACAG
TCATCTTTTCTTGGAGCTGCTAGCCTATCAGTGAATGAAACCTACCACACTATGTGTTTAACAATCAAAGCACTCTTTCA
AATTGTTGTTGGTAAAAGGAGTATAAATGAAATAGGTGGGCCAATAAAAATTGCAAAATATTCAGGGCAATCAGCTAAAA
AGGGACTTATTATGGTTCTATATTTTATGGCAATTATTTCAGCGAATTTAGCTGCAATTAACTTGCTGCCAATACCACTA
CTAGATGGTGGGCATTTATTTCATTATATTATAGAAGCAGTTATACGTAGAGATTTGAGTTTGAAATATCAAAAATATGC
AGCCACTTTTGGTGCTACCATACTGTTTTTGTTGATGGCAGTTGCAATCACAAATGATATTAGGCATCTTTTTTAA

Upstream 100 bases:

>100_bases
TTGTCATTAAACTTTTTTTTAATTTAAAGACTAAACTAAATACTTGTCAAGCAAGGCGCATTTTAATATACTCAACGTTT
GATTAAGATTTAAAACATAG

Downstream 100 bases:

>100_bases
GATACATATGAAAAAGTTATTTCACATACTAATAATAATATTTATTTCTTTTCCCACTCTACTTGTTGCTCTAGAAAATA
AGGAAAAAGTACAGATAAAA

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MELISHQLSAGIYYFLSFSLIISIIVFVHECGHYIVAKACKVKVESFSIGFGPEIFGFNDKSGTRWKLSAFPLGGYVKML
GDTNAASVPVDQQKLTEEEKLYSFHTKPRYQKAAIVFAGPFANMIFTVIAFTIFFSVAGYYRTPPVIGNVIEESAAKQAG
LLPGDTITQINEYKIKYFEDISRVIMSNPETRIEIKYSRNNEEYRTILTPFTVEDRDVFGNIIERKTIGITSINMIGLKQ
SSFLGAASLSVNETYHTMCLTIKALFQIVVGKRSINEIGGPIKIAKYSGQSAKKGLIMVLYFMAIISANLAAINLLPIPL
LDGGHLFHYIIEAVIRRDLSLKYQKYAATFGATILFLLMAVAITNDIRHLF

Sequences:

>Translated_371_residues
MELISHQLSAGIYYFLSFSLIISIIVFVHECGHYIVAKACKVKVESFSIGFGPEIFGFNDKSGTRWKLSAFPLGGYVKML
GDTNAASVPVDQQKLTEEEKLYSFHTKPRYQKAAIVFAGPFANMIFTVIAFTIFFSVAGYYRTPPVIGNVIEESAAKQAG
LLPGDTITQINEYKIKYFEDISRVIMSNPETRIEIKYSRNNEEYRTILTPFTVEDRDVFGNIIERKTIGITSINMIGLKQ
SSFLGAASLSVNETYHTMCLTIKALFQIVVGKRSINEIGGPIKIAKYSGQSAKKGLIMVLYFMAIISANLAAINLLPIPL
LDGGHLFHYIIEAVIRRDLSLKYQKYAATFGATILFLLMAVAITNDIRHLF
>Mature_371_residues
MELISHQLSAGIYYFLSFSLIISIIVFVHECGHYIVAKACKVKVESFSIGFGPEIFGFNDKSGTRWKLSAFPLGGYVKML
GDTNAASVPVDQQKLTEEEKLYSFHTKPRYQKAAIVFAGPFANMIFTVIAFTIFFSVAGYYRTPPVIGNVIEESAAKQAG
LLPGDTITQINEYKIKYFEDISRVIMSNPETRIEIKYSRNNEEYRTILTPFTVEDRDVFGNIIERKTIGITSINMIGLKQ
SSFLGAASLSVNETYHTMCLTIKALFQIVVGKRSINEIGGPIKIAKYSGQSAKKGLIMVLYFMAIISANLAAINLLPIPL
LDGGHLFHYIIEAVIRRDLSLKYQKYAATFGATILFLLMAVAITNDIRHLF

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=205, Percent_Identity=31.219512195122, Blast_Score=111, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 41401; Mature: 41401

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELISHQLSAGIYYFLSFSLIISIIVFVHECGHYIVAKACKVKVESFSIGFGPEIFGFND
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEEEEECCCCCEEECCCC
KSGTRWKLSAFPLGGYVKMLGDTNAASVPVDQQKLTEEEKLYSFHTKPRYQKAAIVFAGP
CCCCEEEEEEECCCCEEEEECCCCCCCCCCCHHHHCHHHHHHHCCCCCCCCEEEEEEECH
FANMIFTVIAFTIFFSVAGYYRTPPVIGNVIEESAAKQAGLLPGDTITQINEYKIKYFED
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
ISRVIMSNPETRIEIKYSRNNEEYRTILTPFTVEDRDVFGNIIERKTIGITSINMIGLKQ
HHHHHHCCCCCEEEEEECCCCCCEEEEECCCEECHHHHHHHHHHHHCCCEEEEEEEECCC
SSFLGAASLSVNETYHTMCLTIKALFQIVVGKRSINEIGGPIKIAKYSGQSAKKGLIMVL
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEECCCCHHCHHHHHH
YFMAIISANLAAINLLPIPLLDGGHLFHYIIEAVIRRDLSLKYQKYAATFGATILFLLMA
HHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VAITNDIRHLF
HHHHHHHHHCC
>Mature Secondary Structure
MELISHQLSAGIYYFLSFSLIISIIVFVHECGHYIVAKACKVKVESFSIGFGPEIFGFND
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEEEEECCCCCEEECCCC
KSGTRWKLSAFPLGGYVKMLGDTNAASVPVDQQKLTEEEKLYSFHTKPRYQKAAIVFAGP
CCCCEEEEEEECCCCEEEEECCCCCCCCCCCHHHHCHHHHHHHCCCCCCCCEEEEEEECH
FANMIFTVIAFTIFFSVAGYYRTPPVIGNVIEESAAKQAGLLPGDTITQINEYKIKYFED
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
ISRVIMSNPETRIEIKYSRNNEEYRTILTPFTVEDRDVFGNIIERKTIGITSINMIGLKQ
HHHHHHCCCCCEEEEEECCCCCCEEEEECCCEECHHHHHHHHHHHHCCCEEEEEEEECCC
SSFLGAASLSVNETYHTMCLTIKALFQIVVGKRSINEIGGPIKIAKYSGQSAKKGLIMVL
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEEEECCCCHHCHHHHHH
YFMAIISANLAAINLLPIPLLDGGHLFHYIIEAVIRRDLSLKYQKYAATFGATILFLLMA
HHHHHHHCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VAITNDIRHLF
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]