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The map label for this gene is infC [H]

Identifier: 190571397

GI number: 190571397

Start: 1072259

End: 1072777

Strand: Reverse

Name: infC [H]

Synonym: WPa_1005

Alternate gene names: 190571397

Gene position: 1072777-1072259 (Counterclockwise)

Preceding gene: 190571398

Following gene: 190571395

Centisome position: 72.36

GC content: 34.3

Gene sequence:

>519_bases
TTGCAAGTCAAAAAGAACAATAAAAACAGAATTAATGAACTCATCACAGCTAAGGAGGTACGCTTAGTTGATCATAGTGG
TGAAATGGTCGGAATTGTTCCAATAGAAAAAGCTTTGGAAGTTGCACAAAGTGTTAATTTAGACTTGGTAGAAATCGCAC
CTGATTCAACTCCTCCAGTATGTAAAATTCTGGACTATAGCAAACAAAAGTATGATATAAAAAAGAAGGCAAGTGAAGCA
AAAAAGAAACAAAAAACATTAACTATAAAAGAAATTAAACTGGGTCCTAATATTGGTGATCACGACTACGAAACAAAATT
GCGTCAAGCAAGGGATTTTCTTGTGCATGGACATAGAATTAAAGTCACAATGAGATTTAGAGGGAGAGAGCTTGTAAACA
CTGAAGTTGGACTGAAAAAATTAGAACGGCTAATTAGAGACGCTGAAGATATTGCAAAAGTAGAATTAGCACCTAAAAGG
GAAGGAAATCAATATTCTTTAACTTTAGCTGCTAAGTAG

Upstream 100 bases:

>100_bases
AGTGAGAAATTTAGGATCGGAAAAACAGGAGTCTTTTTCTTTGGAGAATGCTACTGAATTGCTGTTAAAGATTATTAATT
TGAATTAATGGAGCTAAAAT

Downstream 100 bases:

>100_bases
TAAAATCATTTAAAAGTATAAGTTAAGTTACTATCCTCTCTTCAATTATATGACGAAAATGTCTGATTAATCCTTGAACT
GGCCAAGCTGCAGCATCGCC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MQVKKNNKNRINELITAKEVRLVDHSGEMVGIVPIEKALEVAQSVNLDLVEIAPDSTPPVCKILDYSKQKYDIKKKASEA
KKKQKTLTIKEIKLGPNIGDHDYETKLRQARDFLVHGHRIKVTMRFRGRELVNTEVGLKKLERLIRDAEDIAKVELAPKR
EGNQYSLTLAAK

Sequences:

>Translated_172_residues
MQVKKNNKNRINELITAKEVRLVDHSGEMVGIVPIEKALEVAQSVNLDLVEIAPDSTPPVCKILDYSKQKYDIKKKASEA
KKKQKTLTIKEIKLGPNIGDHDYETKLRQARDFLVHGHRIKVTMRFRGRELVNTEVGLKKLERLIRDAEDIAKVELAPKR
EGNQYSLTLAAK
>Mature_172_residues
MQVKKNNKNRINELITAKEVRLVDHSGEMVGIVPIEKALEVAQSVNLDLVEIAPDSTPPVCKILDYSKQKYDIKKKASEA
KKKQKTLTIKEIKLGPNIGDHDYETKLRQARDFLVHGHRIKVTMRFRGRELVNTEVGLKKLERLIRDAEDIAKVELAPKR
EGNQYSLTLAAK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=172, Percent_Identity=45.3488372093023, Blast_Score=133, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19580; Mature: 19580

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKKNNKNRINELITAKEVRLVDHSGEMVGIVPIEKALEVAQSVNLDLVEIAPDSTPPV
CCCCCCCHHHHHHHHHHHHEEEEECCCCEEEEEEHHHHHHHHHHCCCEEEEECCCCCCCE
CKILDYSKQKYDIKKKASEAKKKQKTLTIKEIKLGPNIGDHDYETKLRQARDFLVHGHRI
EHHHCCCCHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEE
KVTMRFRGRELVNTEVGLKKLERLIRDAEDIAKVELAPKREGNQYSLTLAAK
EEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHEEECCCCCCCEEEEEEEEC
>Mature Secondary Structure
MQVKKNNKNRINELITAKEVRLVDHSGEMVGIVPIEKALEVAQSVNLDLVEIAPDSTPPV
CCCCCCCHHHHHHHHHHHHEEEEECCCCEEEEEEHHHHHHHHHHCCCEEEEECCCCCCCE
CKILDYSKQKYDIKKKASEAKKKQKTLTIKEIKLGPNIGDHDYETKLRQARDFLVHGHRI
EHHHCCCCHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEE
KVTMRFRGRELVNTEVGLKKLERLIRDAEDIAKVELAPKREGNQYSLTLAAK
EEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHEEECCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]