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The map label for this gene is recG [H]

Identifier: 190570903

GI number: 190570903

Start: 518987

End: 521008

Strand: Direct

Name: recG [H]

Synonym: WPa_0482

Alternate gene names: 190570903

Gene position: 518987-521008 (Clockwise)

Preceding gene: 190570901

Following gene: 190570904

Centisome position: 35.01

GC content: 35.66

Gene sequence:

>2022_bases
ATGAGCAATCAGATTTTTCTAAATAGCAGGCTGGAGAATATACCTAAGTTTCATTCCGCAATATTGCCTAAACTTTGCGG
TGGAGACAGAGTAATGGACTTGCTGTTTTATAGGCCGCTCAGTTATGTGGATAGAAGTAAATCACTACCTGATGCTCAAG
TGGGAGAATTTACAACTTTTGTGGCAAAAGTGTATGAGCACCAGCGCCCCACTGTTAGAGGTAGGCCATATAAAATAATC
GTTGAAAGTGAAAGTCAGTATTTATTTATAGTTTTTTTTAATTACTCAGTTAAATATTTGTATAAATTATTTCCAGTTGG
AACAGATATAGTCATCAGTGGTAAACTTGAAAAGTTTGCCGAACGTTGGCAAATTACTCACCCAGATTATATGTTATCTG
ATATCAATCAATTTAAAGAAATAGCCTGCATAGAGCCAATTTACCAATTATGTCGCGGTATTACTAACAAGAGCATTAGA
AACATAATAAGTTCTAATCTAAAAGATTTGCCTGATTTGCCAGAGTGGATAGATGAAACATTAATCAAGCAAAAGAAATG
GCTGAATTGGAAAGAAAGCATCATAAGATTGCACAGACCGAGCTCACTCGCAGAAGCAGAAGTTTGCAGAGAAAGACTTG
CTTATGATGAGCTATTTGCGTACCAGTTGGCACTAAAGCTTGCAAGGGAAAATCATGTAAAAAAAGAGGGAAAAGAATTT
ATAATATTGAGTAAATACAAAGAGCAGGTCTTAAATGAATTACCGTTCCAATTAACAAATGATCAAATTCGAGCGATAGA
TGAAATCTCAGAAAGACAAAAATCCAGATACCGCATGGTAAGTCTGCTGCAAGGTGACGTTGGGAGTGGCAAAACTGTAG
TTGCACTCTTTGCGATGCTGAATGTGGTAGAAAATAACATGCAAGCAGCTCTAATGGCACCAACTACTATCTTGGCTGAG
CAACATTATAATTGGATCGAAGAAGCTCTATCTTGTACTGATATAAAAGTTGCTTTGCTTACCGGTAAAACTGCGCGCAA
GGAAAGAAAGATTATTATGAACGAACTTGCAAGTGGTATTTTAAATATAGTAATTGGTACTCATGCATTATTTCAAGCCA
ACGTTACATTTAAAAATTTAGGACTCGCAGTCATAGACGAACAACAGCGATTTGGAGTGATACAGAGGAATCGGTTGGTA
GGAAAAGGAGAAAATACCGATATACTTTTTGTTACTGCAACTCCCATTCCAAGAACCTTGCAGCAAGCTATGTATGGTGA
TGTTGAATGTTCTATTTTAAGGGAAAAACCAAAATCTAGATTGCCAATAAAAACCGTTATTATGAACGTTAAAAAAGTGT
CAGATATTATTCAAAGACTGAAAGATGCTATAAATAGAGGCGAAAAAGCATATTGGATTTGTCCATACATAGAAGAAAAC
GAAGAACTCAATATTGCCGCAGCAGAAATGCGCTTTCAGGAACTACAAAAGACATTTTTTGATAGAGTTGGAATAATACA
CGGAAAACTAACTCAAGAGCAGAAAGATCAAGTGATGTTTTCCTTCAAGAGAAATGAATTTTCTCTGCTTGTTGCAACCA
CTGTGATAGAAGTTGGCATAGATGTACCAGATGCAACTATTATGATTATAGAGAATGCAGAACAGTTTGGGTTATCGCAA
TTACATCAGTTAAGAGGTAGAGTAGGACGAGGAAATAAACCGTCTTTTTGTGTACTGTTATATGACAATCTCAGTAAAAG
TTCGTATTCAAAGTTAAAGATTATGTGTGAGTCACAAGATGGATTTTATATTGCTGAAAAGGATATGATGCTGAGGGGTA
GCGGAGATATTCTAGGCACAAAACAATCAGGGTGCATGGAGTTTAAATTTGCTGATTTATATGAGGACAGAGAATTGCTC
AACCTTGCATATAATAGTGCAAAAGGTACAATAGCTAATTTTGAATTACTGCTTGATATATTTGAATATAGAAGTAGACT
ACATTTTTCAAAATTTCAGTAA

Upstream 100 bases:

>100_bases
TAGTTAATATGTCAATAATATACTTAACATGGACAGTCATAATAGGGGTGACAGGATTTTAGTAAGGCTCTATAACAGTT
TTACACATGTATGAATCTCA

Downstream 100 bases:

>100_bases
TCTTCCAAGCCATAACCTTCATGAGTAGAAATTCCTTGACAGACGGGAGTATTTAACAAACCATATGCGTCAAGTTAAGG
AAAAATAAGAGTGAAGAAGA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MSNQIFLNSRLENIPKFHSAILPKLCGGDRVMDLLFYRPLSYVDRSKSLPDAQVGEFTTFVAKVYEHQRPTVRGRPYKII
VESESQYLFIVFFNYSVKYLYKLFPVGTDIVISGKLEKFAERWQITHPDYMLSDINQFKEIACIEPIYQLCRGITNKSIR
NIISSNLKDLPDLPEWIDETLIKQKKWLNWKESIIRLHRPSSLAEAEVCRERLAYDELFAYQLALKLARENHVKKEGKEF
IILSKYKEQVLNELPFQLTNDQIRAIDEISERQKSRYRMVSLLQGDVGSGKTVVALFAMLNVVENNMQAALMAPTTILAE
QHYNWIEEALSCTDIKVALLTGKTARKERKIIMNELASGILNIVIGTHALFQANVTFKNLGLAVIDEQQRFGVIQRNRLV
GKGENTDILFVTATPIPRTLQQAMYGDVECSILREKPKSRLPIKTVIMNVKKVSDIIQRLKDAINRGEKAYWICPYIEEN
EELNIAAAEMRFQELQKTFFDRVGIIHGKLTQEQKDQVMFSFKRNEFSLLVATTVIEVGIDVPDATIMIIENAEQFGLSQ
LHQLRGRVGRGNKPSFCVLLYDNLSKSSYSKLKIMCESQDGFYIAEKDMMLRGSGDILGTKQSGCMEFKFADLYEDRELL
NLAYNSAKGTIANFELLLDIFEYRSRLHFSKFQ

Sequences:

>Translated_673_residues
MSNQIFLNSRLENIPKFHSAILPKLCGGDRVMDLLFYRPLSYVDRSKSLPDAQVGEFTTFVAKVYEHQRPTVRGRPYKII
VESESQYLFIVFFNYSVKYLYKLFPVGTDIVISGKLEKFAERWQITHPDYMLSDINQFKEIACIEPIYQLCRGITNKSIR
NIISSNLKDLPDLPEWIDETLIKQKKWLNWKESIIRLHRPSSLAEAEVCRERLAYDELFAYQLALKLARENHVKKEGKEF
IILSKYKEQVLNELPFQLTNDQIRAIDEISERQKSRYRMVSLLQGDVGSGKTVVALFAMLNVVENNMQAALMAPTTILAE
QHYNWIEEALSCTDIKVALLTGKTARKERKIIMNELASGILNIVIGTHALFQANVTFKNLGLAVIDEQQRFGVIQRNRLV
GKGENTDILFVTATPIPRTLQQAMYGDVECSILREKPKSRLPIKTVIMNVKKVSDIIQRLKDAINRGEKAYWICPYIEEN
EELNIAAAEMRFQELQKTFFDRVGIIHGKLTQEQKDQVMFSFKRNEFSLLVATTVIEVGIDVPDATIMIIENAEQFGLSQ
LHQLRGRVGRGNKPSFCVLLYDNLSKSSYSKLKIMCESQDGFYIAEKDMMLRGSGDILGTKQSGCMEFKFADLYEDRELL
NLAYNSAKGTIANFELLLDIFEYRSRLHFSKFQ
>Mature_672_residues
SNQIFLNSRLENIPKFHSAILPKLCGGDRVMDLLFYRPLSYVDRSKSLPDAQVGEFTTFVAKVYEHQRPTVRGRPYKIIV
ESESQYLFIVFFNYSVKYLYKLFPVGTDIVISGKLEKFAERWQITHPDYMLSDINQFKEIACIEPIYQLCRGITNKSIRN
IISSNLKDLPDLPEWIDETLIKQKKWLNWKESIIRLHRPSSLAEAEVCRERLAYDELFAYQLALKLARENHVKKEGKEFI
ILSKYKEQVLNELPFQLTNDQIRAIDEISERQKSRYRMVSLLQGDVGSGKTVVALFAMLNVVENNMQAALMAPTTILAEQ
HYNWIEEALSCTDIKVALLTGKTARKERKIIMNELASGILNIVIGTHALFQANVTFKNLGLAVIDEQQRFGVIQRNRLVG
KGENTDILFVTATPIPRTLQQAMYGDVECSILREKPKSRLPIKTVIMNVKKVSDIIQRLKDAINRGEKAYWICPYIEENE
ELNIAAAEMRFQELQKTFFDRVGIIHGKLTQEQKDQVMFSFKRNEFSLLVATTVIEVGIDVPDATIMIIENAEQFGLSQL
HQLRGRVGRGNKPSFCVLLYDNLSKSSYSKLKIMCESQDGFYIAEKDMMLRGSGDILGTKQSGCMEFKFADLYEDRELLN
LAYNSAKGTIANFELLLDIFEYRSRLHFSKFQ

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=629, Percent_Identity=38.4737678855326, Blast_Score=390, Evalue=1e-109,
Organism=Escherichia coli, GI1787357, Length=429, Percent_Identity=37.2960372960373, Blast_Score=266, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77450; Mature: 77319

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQIFLNSRLENIPKFHSAILPKLCGGDRVMDLLFYRPLSYVDRSKSLPDAQVGEFTTF
CCCCEEECCHHHHCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHH
VAKVYEHQRPTVRGRPYKIIVESESQYLFIVFFNYSVKYLYKLFPVGTDIVISGKLEKFA
HHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHCCCCCEEEECCHHHHH
ERWQITHPDYMLSDINQFKEIACIEPIYQLCRGITNKSIRNIISSNLKDLPDLPEWIDET
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHH
LIKQKKWLNWKESIIRLHRPSSLAEAEVCRERLAYDELFAYQLALKLARENHVKKEGKEF
HHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IILSKYKEQVLNELPFQLTNDQIRAIDEISERQKSRYRMVSLLQGDVGSGKTVVALFAML
EEEHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
NVVENNMQAALMAPTTILAEQHYNWIEEALSCTDIKVALLTGKTARKERKIIMNELASGI
HHHHCCCCEEHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHH
LNIVIGTHALFQANVTFKNLGLAVIDEQQRFGVIQRNRLVGKGENTDILFVTATPIPRTL
HHHHHHHHHHEEECCCHHHCCEEEECCHHHCCHHHHCCEECCCCCCCEEEEECCCCHHHH
QQAMYGDVECSILREKPKSRLPIKTVIMNVKKVSDIIQRLKDAINRGEKAYWICPYIEEN
HHHHCCCCEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEECCC
EELNIAAAEMRFQELQKTFFDRVGIIHGKLTQEQKDQVMFSFKRNEFSLLVATTVIEVGI
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEECCCCEEEHHHHHHHHHCC
DVPDATIMIIENAEQFGLSQLHQLRGRVGRGNKPSFCVLLYDNLSKSSYSKLKIMCESQD
CCCCCEEEEEECCHHHCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCC
GFYIAEKDMMLRGSGDILGTKQSGCMEFKFADLYEDRELLNLAYNSAKGTIANFELLLDI
CEEEECCCEEEECCCCEECCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FEYRSRLHFSKFQ
HHHHHHCCCCCCC
>Mature Secondary Structure 
SNQIFLNSRLENIPKFHSAILPKLCGGDRVMDLLFYRPLSYVDRSKSLPDAQVGEFTTF
CCCEEECCHHHHCHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHH
VAKVYEHQRPTVRGRPYKIIVESESQYLFIVFFNYSVKYLYKLFPVGTDIVISGKLEKFA
HHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCHHHHHHHHHCCCCCEEEECCHHHHH
ERWQITHPDYMLSDINQFKEIACIEPIYQLCRGITNKSIRNIISSNLKDLPDLPEWIDET
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHH
LIKQKKWLNWKESIIRLHRPSSLAEAEVCRERLAYDELFAYQLALKLARENHVKKEGKEF
HHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
IILSKYKEQVLNELPFQLTNDQIRAIDEISERQKSRYRMVSLLQGDVGSGKTVVALFAML
EEEHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
NVVENNMQAALMAPTTILAEQHYNWIEEALSCTDIKVALLTGKTARKERKIIMNELASGI
HHHHCCCCEEHCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHH
LNIVIGTHALFQANVTFKNLGLAVIDEQQRFGVIQRNRLVGKGENTDILFVTATPIPRTL
HHHHHHHHHHEEECCCHHHCCEEEECCHHHCCHHHHCCEECCCCCCCEEEEECCCCHHHH
QQAMYGDVECSILREKPKSRLPIKTVIMNVKKVSDIIQRLKDAINRGEKAYWICPYIEEN
HHHHCCCCEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEECCC
EELNIAAAEMRFQELQKTFFDRVGIIHGKLTQEQKDQVMFSFKRNEFSLLVATTVIEVGI
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEECCCCEEEHHHHHHHHHCC
DVPDATIMIIENAEQFGLSQLHQLRGRVGRGNKPSFCVLLYDNLSKSSYSKLKIMCESQD
CCCCCEEEEEECCHHHCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCEEEEEEECCC
GFYIAEKDMMLRGSGDILGTKQSGCMEFKFADLYEDRELLNLAYNSAKGTIANFELLLDI
CEEEECCCEEEECCCCEECCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
FEYRSRLHFSKFQ
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]