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The map label for this gene is yleA [C]

Identifier: 190570899

GI number: 190570899

Start: 515017

End: 516243

Strand: Reverse

Name: yleA [C]

Synonym: WPa_0478

Alternate gene names: 190570899

Gene position: 516243-515017 (Counterclockwise)

Preceding gene: 190570900

Following gene: 190570898

Centisome position: 34.82

GC content: 32.68

Gene sequence:

>1227_bases
ATGAATGAAGTAATAACATTTGGTTGTCGTCTAAATTTCTACGAGAGTGAGTTAATCAAAGAAGCATTAAAAAAAGCAAA
GAGAGAAAATGTTGTTGTAGTGCATAGCTGTGCAGTGACAAACGAAGCAGAACGCCAAGTGAAGCAAAAAATACGTAAGA
TCTATAAAAACGACCCAAGTAAAGAAATTATCGTAGTTGGCTGTGCCGTTCAATTAGATCCTAAATCATATAGTGATATT
CCTGGTGTAAGTAAAGTGCTAGGTAATCAAGACAAGCTAAGAGCTGAAAATTATCTACTAAATAATGATGAAATCTTAGT
CAGTGATAACCAAGTAGAACCTATTCTCATTAATGGATTTGAAGATAAATCAAGGGCATTTATTGAAATTCAAAATGGTT
GTAATCATAGTTGTACATTTTGCTCAATTACTGAGGCAAGAGGAAATAATCGATCTGTGCCAGTAAACAATATTATAGAG
CAAATTAAGATTTTTATAGAAAATGGGTATCAAGAAGTGGTGTTTACAGGTGTTGATATTACTGACTTTGGTACAGATTT
GTTTGGTAAGCAATCACTTGGTTCGATGGTTAGGAGAGTTTTAAAGGATATACCACAGTTAAAGAGACTAAGACTTTCCT
CTATTGATGTTGCTGAAGTTGATGATGAACTAATGGATTTAATAGCTAATGAGTCAAGACTTATGCCTCACTTACACTTG
AGTCTACAGTCTGGTAATAATTTAATACTAAAGAGAATGAAACGTCGTCACAATAGAGAACAAGTGATAGAATTTTGTCA
TAAAATGAAGAGCTTAAGACCTAATATAGCATTTGGCGCTGATATTATTGCTGGATTTCCAACAGAAACTGATGAAATGT
TTCAGGATACAGTTGATTTACTGAAAAAAATAAATGTAGTTTATCTACATGCTTTTCCATATTCAGAGCGGAAAAACACA
CCTGCTGCACGGATGCCACAAATATCAGAGAATGTACGTAAAGAACGAGTAAAGCATCTAAGAGAAATAAATAAAGAAAT
GATGAGCAGTTTTTATCAATCTTTGCTCGGCACTGAGCAAAGCGTTTTGGTTGAGCAGAATAATATTGGTAGAACAGAAA
ATTTTGCATTAATAAAACTTACATCAAGAGTTCAAGCTAAAAGTATTGTGAAAGCTCATGTTAAAGGAATAGAAAATAAT
TGTTTAATTGGAAATATTATTTCTTAA

Upstream 100 bases:

>100_bases
TTTTCAACTCTAGAGGTTATGCTTAAATTATAATATCTACCAAAAAAATAGTCATTTTGCTTGGATATTTGATATAATTT
AGATCTATTAAAGCAAAAGC

Downstream 100 bases:

>100_bases
TTTTTGTACATTAAAGGAATATATGATATAGTAGTTATACTATAAGTGATAATTCATTTATGATAATTAGAATATCTATT
GCTTTATTTTTCATCTTCAT

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MNEVITFGCRLNFYESELIKEALKKAKRENVVVVHSCAVTNEAERQVKQKIRKIYKNDPSKEIIVVGCAVQLDPKSYSDI
PGVSKVLGNQDKLRAENYLLNNDEILVSDNQVEPILINGFEDKSRAFIEIQNGCNHSCTFCSITEARGNNRSVPVNNIIE
QIKIFIENGYQEVVFTGVDITDFGTDLFGKQSLGSMVRRVLKDIPQLKRLRLSSIDVAEVDDELMDLIANESRLMPHLHL
SLQSGNNLILKRMKRRHNREQVIEFCHKMKSLRPNIAFGADIIAGFPTETDEMFQDTVDLLKKINVVYLHAFPYSERKNT
PAARMPQISENVRKERVKHLREINKEMMSSFYQSLLGTEQSVLVEQNNIGRTENFALIKLTSRVQAKSIVKAHVKGIENN
CLIGNIIS

Sequences:

>Translated_408_residues
MNEVITFGCRLNFYESELIKEALKKAKRENVVVVHSCAVTNEAERQVKQKIRKIYKNDPSKEIIVVGCAVQLDPKSYSDI
PGVSKVLGNQDKLRAENYLLNNDEILVSDNQVEPILINGFEDKSRAFIEIQNGCNHSCTFCSITEARGNNRSVPVNNIIE
QIKIFIENGYQEVVFTGVDITDFGTDLFGKQSLGSMVRRVLKDIPQLKRLRLSSIDVAEVDDELMDLIANESRLMPHLHL
SLQSGNNLILKRMKRRHNREQVIEFCHKMKSLRPNIAFGADIIAGFPTETDEMFQDTVDLLKKINVVYLHAFPYSERKNT
PAARMPQISENVRKERVKHLREINKEMMSSFYQSLLGTEQSVLVEQNNIGRTENFALIKLTSRVQAKSIVKAHVKGIENN
CLIGNIIS
>Mature_408_residues
MNEVITFGCRLNFYESELIKEALKKAKRENVVVVHSCAVTNEAERQVKQKIRKIYKNDPSKEIIVVGCAVQLDPKSYSDI
PGVSKVLGNQDKLRAENYLLNNDEILVSDNQVEPILINGFEDKSRAFIEIQNGCNHSCTFCSITEARGNNRSVPVNNIIE
QIKIFIENGYQEVVFTGVDITDFGTDLFGKQSLGSMVRRVLKDIPQLKRLRLSSIDVAEVDDELMDLIANESRLMPHLHL
SLQSGNNLILKRMKRRHNREQVIEFCHKMKSLRPNIAFGADIIAGFPTETDEMFQDTVDLLKKINVVYLHAFPYSERKNT
PAARMPQISENVRKERVKHLREINKEMMSSFYQSLLGTEQSVLVEQNNIGRTENFALIKLTSRVQAKSIVKAHVKGIENN
CLIGNIIS

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=395, Percent_Identity=27.5949367088608, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI28872784, Length=416, Percent_Identity=25, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI28872782, Length=416, Percent_Identity=25, Blast_Score=138, Evalue=8e-33,
Organism=Escherichia coli, GI1786882, Length=404, Percent_Identity=27.4752475247525, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787057, Length=394, Percent_Identity=24.8730964467005, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17553146, Length=437, Percent_Identity=25.858123569794, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71996771, Length=242, Percent_Identity=28.9256198347107, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21356207, Length=420, Percent_Identity=27.3809523809524, Blast_Score=171, Evalue=6e-43,
Organism=Drosophila melanogaster, GI19922432, Length=365, Percent_Identity=27.9452054794521, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 46419; Mature: 46419

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVITFGCRLNFYESELIKEALKKAKRENVVVVHSCAVTNEAERQVKQKIRKIYKNDPS
CCCEEEEEEEECHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCC
KEIIVVGCAVQLDPKSYSDIPGVSKVLGNQDKLRAENYLLNNDEILVSDNQVEPILINGF
CEEEEEEEEEEECCCCCCCCCCHHHHHCCCHHHHHHHEEECCCEEEEECCCCCEEEEECC
EDKSRAFIEIQNGCNHSCTFCSITEARGNNRSVPVNNIIEQIKIFIENGYQEVVFTGVDI
CCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCH
TDFGTDLFGKQSLGSMVRRVLKDIPQLKRLRLSSIDVAEVDDELMDLIANESRLMPHLHL
HHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEE
SLQSGNNLILKRMKRRHNREQVIEFCHKMKSLRPNIAFGADIIAGFPTETDEMFQDTVDL
EECCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEECCHHHCCCCCCHHHHHHHHHHH
LKKINVVYLHAFPYSERKNTPAARMPQISENVRKERVKHLREINKEMMSSFYQSLLGTEQ
HHHCCEEEEEECCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SVLVEQNNIGRTENFALIKLTSRVQAKSIVKAHVKGIENNCLIGNIIS
HEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEECCCCC
>Mature Secondary Structure
MNEVITFGCRLNFYESELIKEALKKAKRENVVVVHSCAVTNEAERQVKQKIRKIYKNDPS
CCCEEEEEEEECHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCC
KEIIVVGCAVQLDPKSYSDIPGVSKVLGNQDKLRAENYLLNNDEILVSDNQVEPILINGF
CEEEEEEEEEEECCCCCCCCCCHHHHHCCCHHHHHHHEEECCCEEEEECCCCCEEEEECC
EDKSRAFIEIQNGCNHSCTFCSITEARGNNRSVPVNNIIEQIKIFIENGYQEVVFTGVDI
CCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCH
TDFGTDLFGKQSLGSMVRRVLKDIPQLKRLRLSSIDVAEVDDELMDLIANESRLMPHLHL
HHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEE
SLQSGNNLILKRMKRRHNREQVIEFCHKMKSLRPNIAFGADIIAGFPTETDEMFQDTVDL
EECCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEECCHHHCCCCCCHHHHHHHHHHH
LKKINVVYLHAFPYSERKNTPAARMPQISENVRKERVKHLREINKEMMSSFYQSLLGTEQ
HHHCCEEEEEECCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SVLVEQNNIGRTENFALIKLTSRVQAKSIVKAHVKGIENNCLIGNIIS
HEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]