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The map label for this gene is murC [H]

Identifier: 190570659

GI number: 190570659

Start: 213819

End: 214787

Strand: Reverse

Name: murC [H]

Synonym: WPa_0207

Alternate gene names: 190570659

Gene position: 214787-213819 (Counterclockwise)

Preceding gene: 190570660

Following gene: 190570658

Centisome position: 14.49

GC content: 35.6

Gene sequence:

>969_bases
ATGCAACAAAGTGGAAGAAAATACTTATTACAAGGGTTAGTGATATGTCAGTGTTGCAAATCCGTTTATTATGGAATGAG
TAATGCTAAGGGAGGAAGAAGTTACTATCGTTGTCCTGGAAAACGTTTTGGTGAATGTAACAGCAAATCAATACGCGCGG
ATATACTAGAAGAGGTAGTATGGGAAGAAGTGAAGATGTTAAGAGGGCATATAACGAAGGAAAAGTGTGATTTATCAGAG
GTAGATTGGGAGACTAAATTTAATATAATTAGAAAGTTAGTTCAGCGTATTGAAATTGATGATGATAATGTACATATGGT
GTTTCGATTAAAAGAACTCGCTCTCGAAAGACAAAAAGAAGATATCCAACCTTGTACCAGAATTATAAAGAATGTAGTGC
TATCAAATGCAATAGGAATGCATAAAATTAGCAACGCCCTGGCTGCAATATCAGTTGCAGTGAAACTTGGAATTAGTGAT
GAAGAGATTAAAAAAGGTCTTTTGGAATTTAAAGGAGTAGCAAGGAGATTTTCATTAATTGCCGATATTAAAGGTGTTAA
GTTAATTGAGGATTATGCTCACCACCCAAATGAAATACAGGCAACCCTGTCAGCAGCACGTTTGACCACTAAAGGAAAGG
TAACAGGAATTATCGAGCCGCTTCGTTTTGCTCGTGTTCGTAATTTTTTTGATGAGTTCGTACGAATTTTCATGATGTTT
GATTATGTAATTCTCACTCCTGTCCATCCTCCAGAAGATAAGCCTATTCCTGGCTGTGGAATTGATGATATACAAAAAGC
CTTGATCAGTAATGGGTTTAATGATGTGAAGATTATGAATGATGCTTTACTCATTTCACATTTTATTAGTAATTCGACAA
GTTCAGGAGATGTAGTATTATTTATTGGTGCTGGTAGTAATATAGCTAAACTAGCGAAAGAAACTGCAAAGCTGCTGCTA
GTAAAATAA

Upstream 100 bases:

>100_bases
TTCCTTGATTTGGCTCATTATATGCGTATTTTACTATAGGCAAAATATATATAAGTCGTAGAGATACAGTTTGGAAAAAG
AAAAGCTACAAATAGAAAAA

Downstream 100 bases:

>100_bases
ACTTAAGCATTGGTGATTTATATGATAAAATTGTGTAGTAAAACTGGATCCCAGTGTCTAGGCAAACAACTGTACAGACA
TTGCGATATGGGGATAGCTT

Product: murC-like protein

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MQQSGRKYLLQGLVICQCCKSVYYGMSNAKGGRSYYRCPGKRFGECNSKSIRADILEEVVWEEVKMLRGHITKEKCDLSE
VDWETKFNIIRKLVQRIEIDDDNVHMVFRLKELALERQKEDIQPCTRIIKNVVLSNAIGMHKISNALAAISVAVKLGISD
EEIKKGLLEFKGVARRFSLIADIKGVKLIEDYAHHPNEIQATLSAARLTTKGKVTGIIEPLRFARVRNFFDEFVRIFMMF
DYVILTPVHPPEDKPIPGCGIDDIQKALISNGFNDVKIMNDALLISHFISNSTSSGDVVLFIGAGSNIAKLAKETAKLLL
VK

Sequences:

>Translated_322_residues
MQQSGRKYLLQGLVICQCCKSVYYGMSNAKGGRSYYRCPGKRFGECNSKSIRADILEEVVWEEVKMLRGHITKEKCDLSE
VDWETKFNIIRKLVQRIEIDDDNVHMVFRLKELALERQKEDIQPCTRIIKNVVLSNAIGMHKISNALAAISVAVKLGISD
EEIKKGLLEFKGVARRFSLIADIKGVKLIEDYAHHPNEIQATLSAARLTTKGKVTGIIEPLRFARVRNFFDEFVRIFMMF
DYVILTPVHPPEDKPIPGCGIDDIQKALISNGFNDVKIMNDALLISHFISNSTSSGDVVLFIGAGSNIAKLAKETAKLLL
VK
>Mature_322_residues
MQQSGRKYLLQGLVICQCCKSVYYGMSNAKGGRSYYRCPGKRFGECNSKSIRADILEEVVWEEVKMLRGHITKEKCDLSE
VDWETKFNIIRKLVQRIEIDDDNVHMVFRLKELALERQKEDIQPCTRIIKNVVLSNAIGMHKISNALAAISVAVKLGISD
EEIKKGLLEFKGVARRFSLIADIKGVKLIEDYAHHPNEIQATLSAARLTTKGKVTGIIEPLRFARVRNFFDEFVRIFMMF
DYVILTPVHPPEDKPIPGCGIDDIQKALISNGFNDVKIMNDALLISHFISNSTSSGDVVLFIGAGSNIAKLAKETAKLLL
VK

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=198, Percent_Identity=31.8181818181818, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 36203; Mature: 36203

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQSGRKYLLQGLVICQCCKSVYYGMSNAKGGRSYYRCPGKRFGECNSKSIRADILEEVV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHH
WEEVKMLRGHITKEKCDLSEVDWETKFNIIRKLVQRIEIDDDNVHMVFRLKELALERQKE
HHHHHHHHHHCCHHHCCCHHCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHH
DIQPCTRIIKNVVLSNAIGMHKISNALAAISVAVKLGISDEEIKKGLLEFKGVARRFSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ADIKGVKLIEDYAHHPNEIQATLSAARLTTKGKVTGIIEPLRFARVRNFFDEFVRIFMMF
HHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYVILTPVHPPEDKPIPGCGIDDIQKALISNGFNDVKIMNDALLISHFISNSTSSGDVVL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEE
FIGAGSNIAKLAKETAKLLLVK
EEECCCHHHHHHHHHHHHEECC
>Mature Secondary Structure
MQQSGRKYLLQGLVICQCCKSVYYGMSNAKGGRSYYRCPGKRFGECNSKSIRADILEEVV
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHH
WEEVKMLRGHITKEKCDLSEVDWETKFNIIRKLVQRIEIDDDNVHMVFRLKELALERQKE
HHHHHHHHHHCCHHHCCCHHCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHH
DIQPCTRIIKNVVLSNAIGMHKISNALAAISVAVKLGISDEEIKKGLLEFKGVARRFSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
ADIKGVKLIEDYAHHPNEIQATLSAARLTTKGKVTGIIEPLRFARVRNFFDEFVRIFMMF
HHHCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYVILTPVHPPEDKPIPGCGIDDIQKALISNGFNDVKIMNDALLISHFISNSTSSGDVVL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEE
FIGAGSNIAKLAKETAKLLLVK
EEECCCHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA