The gene/protein map for NC_010981 is currently unavailable.
Definition Wolbachia endosymbiont of Culex quinquefasciatus Pel, complete genome.
Accession NC_010981
Length 1,482,455

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The map label for this gene is gltX

Identifier: 190570625

GI number: 190570625

Start: 174528

End: 175862

Strand: Direct

Name: gltX

Synonym: WPa_0166

Alternate gene names: 190570625

Gene position: 174528-175862 (Clockwise)

Preceding gene: 190570622

Following gene: 190570633

Centisome position: 11.77

GC content: 34.38

Gene sequence:

>1335_bases
ATGCTAACAAGATTCGCTCCAAGCCCAACTGGCTACCTACATGTAGGAAACATACGCACTGCACTCATTTGTTGGATGTA
CACACGTAATCAAAATGGAAAATTTTTACTACGTTTTGATGATACTGATCTTGAGCGTTCAGATATCAAATATGTAGATA
ATATCATAGAAGACCTAAAATGGATTGGCATAAATTGGAATTCAAGTTTTAAGCAATCAGAGCGTTTTGAGCGCTATAAC
GAGGTGTTCTTACAGTTAATGAAAGAAGGTCATATTTATGCATGTTATGAAACAAGAGAAGAATTAGACACTAAACGAAA
ATTGCAATTAAAACAAGGTTTCCCCCCTGTTTACGATAAAGGTGCGTTGCTTTTAACTGAGCAAGAGAAAATTCGTTATG
AGCAAGAAGGACGAAAACCACATTTCAGATTTAAATTGGATAGAAATAAAACTGTAAAATGGAATGATGAAGTTAAAGGC
GAAATAAATATTGCAACAATTCATATCAGCGATCCTGTAGTAAAAAGAGAAGATGGAATTTATACGTACATGCTACCTTC
TGTTATTGATGACATTGACTTTAATGTAACCCATGTTGTACGTGGGGAAGATCATGTAACTAATACCGCAGTTCAGATTC
AAATGATTCAAGCATTAAAAGCGAAAATTCCTATCTTTGCCCACCTTCCCTTACTACACTTTGATGATAGCAAAATATCG
AAACGGAAAGGCGGGCTGGATATTAAGTCCATAAGAGAAGATGAGATTGAATCAATGGCGCTAACTAGCTATTTAGCAAA
GCTTGGAACATCTGATCCGATAGAAGCTTATATTGATATGCAGTCTTTAATTGACTCATTTGATATCAAAAAATTTAGTT
CAGCATCTTTACAATTCAGCTTGAGTGAAATGTATAAGCTAAATAGCAAAGTGCTACAACAAATGCCATTTGAAATGGTG
CAAGATCGTTTAAGTCAAATTGGCTCAGAGTTTTGGTATTTTATAAGGAGTAATATAGAAAAGTTTTCTGAAGTGGCCAA
ATGGTGGAAAATATGCAAATTTGGTATAGAACCTGTGGTTCTTAATAAAGAGTTTATAAAAATAGCGCTAAGCACATTAC
CTCAAGGTGATTGTAATGAAAACACATTATCAGAGTGGGTTAAAAATATTCGACAGACAATTGATATAAAGGCAAAAGAT
CTATTTATGCAGTTGCGCCTCGCTTTAACAGGAACAGAAACAGGTCCAGAACTCGCTAAATTATTAATTTTTATCGGTAG
AGAGAGCATTATTGCAAGGTTAGAAGAAAGCCAAAGAATTATACAAAAGGTTTAA

Upstream 100 bases:

>100_bases
TGTTCGCTGTACTTTGTAGCAACTAACACCAAGACAAAGAAGAATCTTGCTTTAGCAGTACATTTATATAAAATTAAAAT
AAACTAAAGTAATCATTTAA

Downstream 100 bases:

>100_bases
ATGCACCGAATGTATTTTGAATGACACCAATAAGCATTGTTCAGGAAATGTGAAAATATTAGATTTCTTGTCATTCCAGT
TTCTGCTCCTGTCATTCAAG

Product: glutamyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamate--tRNA ligase 1; GluRS 1

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MLTRFAPSPTGYLHVGNIRTALICWMYTRNQNGKFLLRFDDTDLERSDIKYVDNIIEDLKWIGINWNSSFKQSERFERYN
EVFLQLMKEGHIYACYETREELDTKRKLQLKQGFPPVYDKGALLLTEQEKIRYEQEGRKPHFRFKLDRNKTVKWNDEVKG
EINIATIHISDPVVKREDGIYTYMLPSVIDDIDFNVTHVVRGEDHVTNTAVQIQMIQALKAKIPIFAHLPLLHFDDSKIS
KRKGGLDIKSIREDEIESMALTSYLAKLGTSDPIEAYIDMQSLIDSFDIKKFSSASLQFSLSEMYKLNSKVLQQMPFEMV
QDRLSQIGSEFWYFIRSNIEKFSEVAKWWKICKFGIEPVVLNKEFIKIALSTLPQGDCNENTLSEWVKNIRQTIDIKAKD
LFMQLRLALTGTETGPELAKLLIFIGRESIIARLEESQRIIQKV

Sequences:

>Translated_444_residues
MLTRFAPSPTGYLHVGNIRTALICWMYTRNQNGKFLLRFDDTDLERSDIKYVDNIIEDLKWIGINWNSSFKQSERFERYN
EVFLQLMKEGHIYACYETREELDTKRKLQLKQGFPPVYDKGALLLTEQEKIRYEQEGRKPHFRFKLDRNKTVKWNDEVKG
EINIATIHISDPVVKREDGIYTYMLPSVIDDIDFNVTHVVRGEDHVTNTAVQIQMIQALKAKIPIFAHLPLLHFDDSKIS
KRKGGLDIKSIREDEIESMALTSYLAKLGTSDPIEAYIDMQSLIDSFDIKKFSSASLQFSLSEMYKLNSKVLQQMPFEMV
QDRLSQIGSEFWYFIRSNIEKFSEVAKWWKICKFGIEPVVLNKEFIKIALSTLPQGDCNENTLSEWVKNIRQTIDIKAKD
LFMQLRLALTGTETGPELAKLLIFIGRESIIARLEESQRIIQKV
>Mature_444_residues
MLTRFAPSPTGYLHVGNIRTALICWMYTRNQNGKFLLRFDDTDLERSDIKYVDNIIEDLKWIGINWNSSFKQSERFERYN
EVFLQLMKEGHIYACYETREELDTKRKLQLKQGFPPVYDKGALLLTEQEKIRYEQEGRKPHFRFKLDRNKTVKWNDEVKG
EINIATIHISDPVVKREDGIYTYMLPSVIDDIDFNVTHVVRGEDHVTNTAVQIQMIQALKAKIPIFAHLPLLHFDDSKIS
KRKGGLDIKSIREDEIESMALTSYLAKLGTSDPIEAYIDMQSLIDSFDIKKFSSASLQFSLSEMYKLNSKVLQQMPFEMV
QDRLSQIGSEFWYFIRSNIEKFSEVAKWWKICKFGIEPVVLNKEFIKIALSTLPQGDCNENTLSEWVKNIRQTIDIKAKD
LFMQLRLALTGTETGPELAKLLIFIGRESIIARLEESQRIIQKV

Specific function: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction:glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI134288884, Length=483, Percent_Identity=26.2939958592132, Blast_Score=162, Evalue=8e-40,
Organism=Homo sapiens, GI4826960, Length=106, Percent_Identity=31.1320754716981, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI62241042, Length=242, Percent_Identity=25.6198347107438, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788743, Length=465, Percent_Identity=30.752688172043, Blast_Score=245, Evalue=4e-66,
Organism=Escherichia coli, GI226510925, Length=248, Percent_Identity=29.0322580645161, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786895, Length=150, Percent_Identity=30.6666666666667, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71993394, Length=476, Percent_Identity=27.1008403361345, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324540, Length=498, Percent_Identity=27.710843373494, Blast_Score=163, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6321192, Length=246, Percent_Identity=27.6422764227642, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324742, Length=114, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665321, Length=479, Percent_Identity=29.4363256784969, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24649466, Length=248, Percent_Identity=25, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYE1_WOLPP (B3CNK5)

Other databases:

- EMBL:   AM999887
- RefSeq:   YP_001974983.1
- EnsemblBacteria:   EBWOLT00000000671
- GeneID:   6385170
- GenomeReviews:   AM999887_GR
- KEGG:   wpi:WPa_0166
- GeneTree:   EBGT00050000030976
- HOGENOM:   HBG628189
- OMA:   PHWRFKL
- ProtClustDB:   PRK12558
- GO:   GO:0005737
- HAMAP:   MF_00022_B
- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR004527
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR014729
- Gene3D:   G3DSA:1.10.1160.10
- Gene3D:   G3DSA:3.40.50.620
- Gene3D:   G3DSA:1.10.10.350
- PANTHER:   PTHR10119
- PRINTS:   PR00987
- TIGRFAMs:   TIGR00464

Pfam domain/function: PF00749 tRNA-synt_1c; SSF48163 tRNA-synt_bind

EC number: =6.1.1.17

Molecular weight: Translated: 51763; Mature: 51763

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 241-241

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MLTRFAPSPTGYLHVGNIRTALICWMYTRNQNGKFLLRFDDTDLERSDIKYVDNIIEDLK
CCCCCCCCCCCEEEECCHHEEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHE
WIGINWNSSFKQSERFERYNEVFLQLMKEGHIYACYETREELDTKRKLQLKQGFPPVYDK
EEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCHHHHHHHHCCCCCCCCC
GALLLTEQEKIRYEQEGRKPHFRFKLDRNKTVKWNDEVKGEINIATIHISDPVVKREDGI
CEEEEECHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCCEEEEEEEEECCCCEECCCCE
YTYMLPSVIDDIDFNVTHVVRGEDHVTNTAVQIQMIQALKAKIPIFAHLPLLHFDDSKIS
EEEECHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEECCEEEECCCHHH
KRKGGLDIKSIREDEIESMALTSYLAKLGTSDPIEAYIDMQSLIDSFDIKKFSSASLQFS
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEE
LSEMYKLNSKVLQQMPFEMVQDRLSQIGSEFWYFIRSNIEKFSEVAKWWKICKFGIEPVV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LNKEFIKIALSTLPQGDCNENTLSEWVKNIRQTIDIKAKDLFMQLRLALTGTETGPELAK
ECHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCHHHHH
LLIFIGRESIIARLEESQRIIQKV
HHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTRFAPSPTGYLHVGNIRTALICWMYTRNQNGKFLLRFDDTDLERSDIKYVDNIIEDLK
CCCCCCCCCCCEEEECCHHEEEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHE
WIGINWNSSFKQSERFERYNEVFLQLMKEGHIYACYETREELDTKRKLQLKQGFPPVYDK
EEECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHCHHHHHHHHCCCCCCCCC
GALLLTEQEKIRYEQEGRKPHFRFKLDRNKTVKWNDEVKGEINIATIHISDPVVKREDGI
CEEEEECHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCCEEEEEEEEECCCCEECCCCE
YTYMLPSVIDDIDFNVTHVVRGEDHVTNTAVQIQMIQALKAKIPIFAHLPLLHFDDSKIS
EEEECHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEECCEEEECCCHHH
KRKGGLDIKSIREDEIESMALTSYLAKLGTSDPIEAYIDMQSLIDSFDIKKFSSASLQFS
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEE
LSEMYKLNSKVLQQMPFEMVQDRLSQIGSEFWYFIRSNIEKFSEVAKWWKICKFGIEPVV
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LNKEFIKIALSTLPQGDCNENTLSEWVKNIRQTIDIKAKDLFMQLRLALTGTETGPELAK
ECHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCHHHHH
LLIFIGRESIIARLEESQRIIQKV
HHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA