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The map label for this gene is typA [H]

Identifier: 190570624

GI number: 190570624

Start: 172476

End: 174305

Strand: Reverse

Name: typA [H]

Synonym: WPa_0165

Alternate gene names: 190570624

Gene position: 174305-172476 (Counterclockwise)

Preceding gene: 190570626

Following gene: 190570623

Centisome position: 11.76

GC content: 38.91

Gene sequence:

>1830_bases
ATGAGTGAATTTAAATCAATCCGCAATATTGCAATAATTGCACACGTTGACCACGGAAAAACTACTTTACTTGATAACAT
GTTAAAACAAAGTGGCACGTTTCGTGAGAATCAAGAAGTTCAAGAACGAGTGATGGATAGTGGTGATCAAGAACGTGAAC
GTGGGATTACAATACTTGCAAAATGTACGTCAATAATGTGGGGTGATGAGAAAATCAATATCATTGATACACCAGGACAT
GCGGATTTTGGTGGAGAAGTGGAAAGGGTGCTCTGCATGGCAGATGGTGTATTACTACTGGTTGATGCTGCAGAAGGTCC
AATGCCACAGACTAAGTTTGTGTTGTCAAAAGCACTAAAGGCAAATTTAAAACCGATTGTGATAATCAATAAGGTTGATC
GACCAGACAGCAGAATTGATGAAGTACTAAATGAAATATATGAGTTATTTTTTAACCTTGATGCAACCAACGAGCAACTA
GATTTTCCAGTACTCTATGCTTCAGGTAGAAATGGTTGGTGTGCTAAGGAGCTATCTGATGAGAGAAAAGATTTAAGCCC
ATTATTTTCAACGGTGATAGATTACATAAAACCTTCCGTTTATGATCAAAATGCACCTTTTGCTATGCTAGTTACTTTAC
TTGAATCTGATAAATTTCTTGGCAGAATATTGACAGGAAAGATTTACCAAGGAATCGCGCAAGTTAACTCAGATCTTAAG
GTAATTGATCTTGATGGTCAAGTGGTTGAGCGAGGGAGATTAACTAAGTTACTCTCATTTTCTGGCTTAAAACGCGTTCC
AGTAGAGCAAGCTGTAGCTGGTGATATCATTGCCATTGCAGGACTTGAGAAAGCTTCAGTTTCAGACACTATAGCAGCAC
CAGAAGTTACAACTGCGATCAGCTCAACTCCAGTTGACCCGCCAACAATGGCGATTACTATAAGCGTGAATGACTCACCT
TTTGCTGGGCAAGAGGGAACAAAACTTACCTCAACTGTTATAAAAGATCGTTTATATGCAGAAGCAGAAACAAACGTTGC
AATTACTGTAACTTTGGCTCCAAGTGGTGAAGCATTTGAAGTAGGTGGACGTGGTGAGTTGCAGCTTGGGGTACTGATTG
AAAATATGAGAAGGGAAGGTTTTGAACTTTCAGTTTCACGGCCTCGAGTGCTGTTTAAAGAAGAAGATGGCAAAAAACTT
GAACCTATAGAGGAAGTAGTAATTGATGTAGATGATGAGTATAGTGGAATCATCATGGAAAAACTTAGCTTTCGAAAAGG
TGAAGTAACTGACATGAGACCTTCTGGTAGTGGCAGAACTAGGTTGACATTTTTAGTGCCATCAAGGGGATTAATTGGCT
ATCAAGGAGAATTTTTAACTGATTCTCGCGGCACTGGTATAATCAACCGTTTATTTCACAGTTATGCTCCACATAAAGGT
TCAATTTCCGGAAGGCGTAATGGGGTTTTAATTTCAACAGACAAAGGCGAAGCAGTAGCGTATGCAATTTTCAATCTGCA
AGATAGGGGAATTATGTTTGTTAAGCCACAAGATAAGGTATATTGTGGTATGATTGTCGGTCAGCATAGTCGTGACAATG
ATTTAGAAATAAATGTACTTAAAGGTAAGCAATTAACAAACGTAAGAGCTTCAGGTAGCGATGAAGCTATAAAGCTTACT
CCACCAAAAATAATGACACTGGAGGATATGATAGCATATATAGACGATGATGAATTGGTAGAAGTAACTCCAAAATCTAT
ACGTTTGCGTAAGAAGTTCCTCGATCCAAATGAACGTAAACGTGCAGGAAGGGCGAAGAATAAAGAGTAA

Upstream 100 bases:

>100_bases
CATGATCTGCCTAAAATACTCTGAAAGCACGGCTTTAGTTATTTACTCTAAATATATTATACGTATACTTGTTATTAAAT
TAAATTTGAAATGATAAGAA

Downstream 100 bases:

>100_bases
TCAACGTTCCTGATAAAAATCTGGATGAGCTACTCGGATAACACCATCATAAAGGGAACCAGTGTCAGTTACTTGAGCAG
GTACTGGGATGACAAGAGAA

Product: GTP-binding protein, typA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MSEFKSIRNIAIIAHVDHGKTTLLDNMLKQSGTFRENQEVQERVMDSGDQERERGITILAKCTSIMWGDEKINIIDTPGH
ADFGGEVERVLCMADGVLLLVDAAEGPMPQTKFVLSKALKANLKPIVIINKVDRPDSRIDEVLNEIYELFFNLDATNEQL
DFPVLYASGRNGWCAKELSDERKDLSPLFSTVIDYIKPSVYDQNAPFAMLVTLLESDKFLGRILTGKIYQGIAQVNSDLK
VIDLDGQVVERGRLTKLLSFSGLKRVPVEQAVAGDIIAIAGLEKASVSDTIAAPEVTTAISSTPVDPPTMAITISVNDSP
FAGQEGTKLTSTVIKDRLYAEAETNVAITVTLAPSGEAFEVGGRGELQLGVLIENMRREGFELSVSRPRVLFKEEDGKKL
EPIEEVVIDVDDEYSGIIMEKLSFRKGEVTDMRPSGSGRTRLTFLVPSRGLIGYQGEFLTDSRGTGIINRLFHSYAPHKG
SISGRRNGVLISTDKGEAVAYAIFNLQDRGIMFVKPQDKVYCGMIVGQHSRDNDLEINVLKGKQLTNVRASGSDEAIKLT
PPKIMTLEDMIAYIDDDELVEVTPKSIRLRKKFLDPNERKRAGRAKNKE

Sequences:

>Translated_609_residues
MSEFKSIRNIAIIAHVDHGKTTLLDNMLKQSGTFRENQEVQERVMDSGDQERERGITILAKCTSIMWGDEKINIIDTPGH
ADFGGEVERVLCMADGVLLLVDAAEGPMPQTKFVLSKALKANLKPIVIINKVDRPDSRIDEVLNEIYELFFNLDATNEQL
DFPVLYASGRNGWCAKELSDERKDLSPLFSTVIDYIKPSVYDQNAPFAMLVTLLESDKFLGRILTGKIYQGIAQVNSDLK
VIDLDGQVVERGRLTKLLSFSGLKRVPVEQAVAGDIIAIAGLEKASVSDTIAAPEVTTAISSTPVDPPTMAITISVNDSP
FAGQEGTKLTSTVIKDRLYAEAETNVAITVTLAPSGEAFEVGGRGELQLGVLIENMRREGFELSVSRPRVLFKEEDGKKL
EPIEEVVIDVDDEYSGIIMEKLSFRKGEVTDMRPSGSGRTRLTFLVPSRGLIGYQGEFLTDSRGTGIINRLFHSYAPHKG
SISGRRNGVLISTDKGEAVAYAIFNLQDRGIMFVKPQDKVYCGMIVGQHSRDNDLEINVLKGKQLTNVRASGSDEAIKLT
PPKIMTLEDMIAYIDDDELVEVTPKSIRLRKKFLDPNERKRAGRAKNKE
>Mature_608_residues
SEFKSIRNIAIIAHVDHGKTTLLDNMLKQSGTFRENQEVQERVMDSGDQERERGITILAKCTSIMWGDEKINIIDTPGHA
DFGGEVERVLCMADGVLLLVDAAEGPMPQTKFVLSKALKANLKPIVIINKVDRPDSRIDEVLNEIYELFFNLDATNEQLD
FPVLYASGRNGWCAKELSDERKDLSPLFSTVIDYIKPSVYDQNAPFAMLVTLLESDKFLGRILTGKIYQGIAQVNSDLKV
IDLDGQVVERGRLTKLLSFSGLKRVPVEQAVAGDIIAIAGLEKASVSDTIAAPEVTTAISSTPVDPPTMAITISVNDSPF
AGQEGTKLTSTVIKDRLYAEAETNVAITVTLAPSGEAFEVGGRGELQLGVLIENMRREGFELSVSRPRVLFKEEDGKKLE
PIEEVVIDVDDEYSGIIMEKLSFRKGEVTDMRPSGSGRTRLTFLVPSRGLIGYQGEFLTDSRGTGIINRLFHSYAPHKGS
ISGRRNGVLISTDKGEAVAYAIFNLQDRGIMFVKPQDKVYCGMIVGQHSRDNDLEINVLKGKQLTNVRASGSDEAIKLTP
PKIMTLEDMIAYIDDDELVEVTPKSIRLRKKFLDPNERKRAGRAKNKE

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=495, Percent_Identity=28.2828282828283, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=44.3609022556391, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI18390331, Length=147, Percent_Identity=43.5374149659864, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4503483, Length=166, Percent_Identity=34.3373493975904, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI25306287, Length=160, Percent_Identity=38.75, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI19923640, Length=160, Percent_Identity=38.75, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI25306283, Length=144, Percent_Identity=40.2777777777778, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI34147630, Length=245, Percent_Identity=31.4285714285714, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=41.4414414414414, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=41.4414414414414, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=41.4414414414414, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI217272892, Length=140, Percent_Identity=35.7142857142857, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI217272894, Length=134, Percent_Identity=36.5671641791045, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI94966752, Length=129, Percent_Identity=32.5581395348837, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI223555963, Length=306, Percent_Identity=26.797385620915, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI5729864, Length=306, Percent_Identity=26.797385620915, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI48994988, Length=603, Percent_Identity=52.4046434494196, Blast_Score=641, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=540, Percent_Identity=25.7407407407407, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI1789738, Length=148, Percent_Identity=39.8648648648649, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1790835, Length=156, Percent_Identity=31.4102564102564, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790412, Length=250, Percent_Identity=27.2, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789737, Length=250, Percent_Identity=27.2, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17557151, Length=234, Percent_Identity=34.6153846153846, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17556745, Length=336, Percent_Identity=28.8690476190476, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71988819, Length=144, Percent_Identity=36.1111111111111, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988811, Length=144, Percent_Identity=36.1111111111111, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17506493, Length=178, Percent_Identity=32.5842696629214, Blast_Score=102, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17533571, Length=133, Percent_Identity=42.8571428571429, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17552882, Length=194, Percent_Identity=33.5051546391753, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17556456, Length=284, Percent_Identity=27.8169014084507, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323320, Length=510, Percent_Identity=27.843137254902, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324707, Length=166, Percent_Identity=37.9518072289157, Blast_Score=114, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6320593, Length=166, Percent_Identity=37.9518072289157, Blast_Score=114, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6323098, Length=137, Percent_Identity=42.3357664233577, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6322359, Length=154, Percent_Identity=38.3116883116883, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=170, Percent_Identity=35.2941176470588, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324761, Length=239, Percent_Identity=28.8702928870293, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322675, Length=140, Percent_Identity=30, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI78706572, Length=401, Percent_Identity=29.1770573566085, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24582462, Length=145, Percent_Identity=44.1379310344828, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI221458488, Length=160, Percent_Identity=41.25, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24585711, Length=170, Percent_Identity=34.7058823529412, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585713, Length=170, Percent_Identity=34.7058823529412, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24585709, Length=170, Percent_Identity=34.7058823529412, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28574573, Length=166, Percent_Identity=36.144578313253, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=40.2985074626866, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281363316, Length=277, Percent_Identity=27.7978339350181, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17864358, Length=277, Percent_Identity=27.7978339350181, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19921738, Length=249, Percent_Identity=27.3092369477912, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28572034, Length=146, Percent_Identity=32.1917808219178, Blast_Score=73, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 67257; Mature: 67126

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEFKSIRNIAIIAHVDHGKTTLLDNMLKQSGTFRENQEVQERVMDSGDQERERGITILA
CCCHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHCCCEEEE
KCTSIMWGDEKINIIDTPGHADFGGEVERVLCMADGVLLLVDAAEGPMPQTKFVLSKALK
EEHHHEECCCEEEEEECCCCCCCCCHHHHHHEEECCEEEEEECCCCCCCHHHHHHHHHHH
ANLKPIVIINKVDRPDSRIDEVLNEIYELFFNLDATNEQLDFPVLYASGRNGWCAKELSD
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHH
ERKDLSPLFSTVIDYIKPSVYDQNAPFAMLVTLLESDKFLGRILTGKIYQGIAQVNSDLK
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCE
VIDLDGQVVERGRLTKLLSFSGLKRVPVEQAVAGDIIAIAGLEKASVSDTIAAPEVTTAI
EEECCCHHHHCCHHHHHHHHCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHH
SSTPVDPPTMAITISVNDSPFAGQEGTKLTSTVIKDRLYAEAETNVAITVTLAPSGEAFE
CCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHEECCCCEEEEEEECCCCCEEE
VGGRGELQLGVLIENMRREGFELSVSRPRVLFKEEDGKKLEPIEEVVIDVDDEYSGIIME
ECCCCCEEEHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCHHHHEEECCCCCCCHHHH
KLSFRKGEVTDMRPSGSGRTRLTFLVPSRGLIGYQGEFLTDSRGTGIINRLFHSYAPHKG
HHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCC
SISGRRNGVLISTDKGEAVAYAIFNLQDRGIMFVKPQDKVYCGMIVGQHSRDNDLEINVL
CCCCCCCCEEEECCCCCEEEEEEEEECCCCEEEECCCCCEEEEEEEECCCCCCCEEEEEE
KGKQLTNVRASGSDEAIKLTPPKIMTLEDMIAYIDDDELVEVTPKSIRLRKKFLDPNERK
CCCEEEEEECCCCCCEEEECCCCEEEHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCHHH
RAGRAKNKE
HCCCCCCCC
>Mature Secondary Structure 
SEFKSIRNIAIIAHVDHGKTTLLDNMLKQSGTFRENQEVQERVMDSGDQERERGITILA
CCHHHHCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHCCCEEEE
KCTSIMWGDEKINIIDTPGHADFGGEVERVLCMADGVLLLVDAAEGPMPQTKFVLSKALK
EEHHHEECCCEEEEEECCCCCCCCCHHHHHHEEECCEEEEEECCCCCCCHHHHHHHHHHH
ANLKPIVIINKVDRPDSRIDEVLNEIYELFFNLDATNEQLDFPVLYASGRNGWCAKELSD
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHH
ERKDLSPLFSTVIDYIKPSVYDQNAPFAMLVTLLESDKFLGRILTGKIYQGIAQVNSDLK
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCE
VIDLDGQVVERGRLTKLLSFSGLKRVPVEQAVAGDIIAIAGLEKASVSDTIAAPEVTTAI
EEECCCHHHHCCHHHHHHHHCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHH
SSTPVDPPTMAITISVNDSPFAGQEGTKLTSTVIKDRLYAEAETNVAITVTLAPSGEAFE
CCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHEECCCCEEEEEEECCCCCEEE
VGGRGELQLGVLIENMRREGFELSVSRPRVLFKEEDGKKLEPIEEVVIDVDDEYSGIIME
ECCCCCEEEHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCHHHHEEECCCCCCCHHHH
KLSFRKGEVTDMRPSGSGRTRLTFLVPSRGLIGYQGEFLTDSRGTGIINRLFHSYAPHKG
HHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCCC
SISGRRNGVLISTDKGEAVAYAIFNLQDRGIMFVKPQDKVYCGMIVGQHSRDNDLEINVL
CCCCCCCCEEEECCCCCEEEEEEEEECCCCEEEECCCCCEEEEEEEECCCCCCCEEEEEE
KGKQLTNVRASGSDEAIKLTPPKIMTLEDMIAYIDDDELVEVTPKSIRLRKKFLDPNERK
CCCEEEEEECCCCCCEEEECCCCEEEHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCHHH
RAGRAKNKE
HCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]