BacMap

Definition	Wolbachia endosymbiont of Culex quinquefasciatus Pel, complete genome.
Accession	NC_010981
Length	1,482,455

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The map label for this gene is znuC [H]

Identifier: 190570608

GI number: 190570608

Start: 152508

End: 153239

Strand: Direct

Name: znuC [H]

Synonym: WPa_0146

Alternate gene names: 190570608

Gene position: 152508-153239 (Clockwise)

Preceding gene: 190570606

Following gene: 190570609

Centisome position: 10.29

GC content: 32.24

Gene sequence:

>732_bases
ATGTCTCATATAAATGTTGAGAAGAAGTCAATTTTTGCCAAAAAATTAAGTAGTGTCAATAACTGCATTCTAAAAATAGA
AAACCTTACTCTTTCATACGGTAACAAAAAAGTTCTTGATAATATCAACATATCAGTACAAAGAGGAGATATAGTTACAA
TACTTGGTCCAAATGGCGGAGGTAAAACCTCTTTAGTGAAAGCAGTTGCTGGTATAAATAAAGGTTTTATTGGCAGTATT
GTATTCGCTGACAATATAAAAATTAGCTATATGCCACAAAATTTTAGTATTGGTAATTTGATGCCAATAACAGTTGAGTC
TTTCCTTTTCAATAGCTCCTCGAAGAAATTGAAGAAAAATCAACCCATTGTTACAGAAGCAATAGAATTGGTTGGTATCG
GTAACATCCTAAAAAATCAAGTATTAGAAATCTCTGCAGGACAAACACAATTACTGCTGCTTGCACGCTGTTTAATTTCA
GAATCTGATTTGATCATTTTAGATGAGCCAGTCAGTGCAATGGATATTAACGCACGATCTAAATTTTATGATATTATAAA
TAAAATCGCAAAAGAACGATCAGTGTCGATTCTCATGACTTCTCATGACCTTAACTCTGCTCTACCATCCTCAGATTACA
TAATTTGCATAAATAATACTATCTATTATCAAGGTAAACCTGATGAAATTATGGAGATAAATGAAATATTTGGCAGTTAC
GCAGCGAAATGA

Upstream 100 bases:

>100_bases
GTGAGTGTATAGGTTTGATTGTAGCTACAATTTTTAAATTGGATGAAAAGGCACTATTGTAGTATAATGTAAATGAAAGT
AATAGAAAAAAAAACAGTAA

Downstream 100 bases:

>100_bases
TTCAAAATATTCTACGTCTTCTGCAAATAACTACAGTGCTAACACGCTACAATGTGTTACCTTATTTACTTCCACCATCA
AAAAAATCAATAAATAAAAT

Product: Putative cation ABC transporter, ATP-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MSHINVEKKSIFAKKLSSVNNCILKIENLTLSYGNKKVLDNINISVQRGDIVTILGPNGGGKTSLVKAVAGINKGFIGSI
VFADNIKISYMPQNFSIGNLMPITVESFLFNSSSKKLKKNQPIVTEAIELVGIGNILKNQVLEISAGQTQLLLLARCLIS
ESDLIILDEPVSAMDINARSKFYDIINKIAKERSVSILMTSHDLNSALPSSDYIICINNTIYYQGKPDEIMEINEIFGSY
AAK

Sequences:

>Translated_243_residues
MSHINVEKKSIFAKKLSSVNNCILKIENLTLSYGNKKVLDNINISVQRGDIVTILGPNGGGKTSLVKAVAGINKGFIGSI
VFADNIKISYMPQNFSIGNLMPITVESFLFNSSSKKLKKNQPIVTEAIELVGIGNILKNQVLEISAGQTQLLLLARCLIS
ESDLIILDEPVSAMDINARSKFYDIINKIAKERSVSILMTSHDLNSALPSSDYIICINNTIYYQGKPDEIMEINEIFGSY
AAK
>Mature_242_residues
SHINVEKKSIFAKKLSSVNNCILKIENLTLSYGNKKVLDNINISVQRGDIVTILGPNGGGKTSLVKAVAGINKGFIGSIV
FADNIKISYMPQNFSIGNLMPITVESFLFNSSSKKLKKNQPIVTEAIELVGIGNILKNQVLEISAGQTQLLLLARCLISE
SDLIILDEPVSAMDINARSKFYDIINKIAKERSVSILMTSHDLNSALPSSDYIICINNTIYYQGKPDEIMEINEIFGSYA
AK

Specific function: Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system [H]

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27881501, Length=202, Percent_Identity=28.7128712871287, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI30795238, Length=202, Percent_Identity=28.7128712871287, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI27436953, Length=173, Percent_Identity=26.0115606936416, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI9955970, Length=210, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI66529005, Length=217, Percent_Identity=27.6497695852535, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI110832837, Length=236, Percent_Identity=26.6949152542373, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31657092, Length=202, Percent_Identity=23.7623762376238, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI190343023, Length=227, Percent_Identity=28.6343612334802, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1788165, Length=224, Percent_Identity=31.25, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI87081791, Length=222, Percent_Identity=30.1801801801802, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87081709, Length=223, Percent_Identity=29.1479820627803, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788761, Length=224, Percent_Identity=25, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1786803, Length=237, Percent_Identity=26.1603375527426, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790739, Length=229, Percent_Identity=27.5109170305677, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787712, Length=207, Percent_Identity=26.5700483091787, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787370, Length=222, Percent_Identity=26.5765765765766, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1786253, Length=221, Percent_Identity=28.5067873303167, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87081782, Length=229, Percent_Identity=29.6943231441048, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786563, Length=204, Percent_Identity=27.4509803921569, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786345, Length=230, Percent_Identity=23.0434782608696, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI48995001, Length=213, Percent_Identity=28.169014084507, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082267, Length=222, Percent_Identity=24.3243243243243, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994943, Length=223, Percent_Identity=25.5605381165919, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790467, Length=219, Percent_Identity=25.5707762557078, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787164, Length=191, Percent_Identity=26.7015706806283, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789672, Length=229, Percent_Identity=26.2008733624454, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788225, Length=227, Percent_Identity=25.1101321585903, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786698, Length=194, Percent_Identity=25.7731958762887, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787500, Length=224, Percent_Identity=22.3214285714286, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1788053, Length=201, Percent_Identity=23.3830845771144, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1789991, Length=215, Percent_Identity=26.046511627907, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367384, Length=188, Percent_Identity=25, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1786319, Length=221, Percent_Identity=26.2443438914027, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789032, Length=227, Percent_Identity=26.8722466960352, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786703, Length=225, Percent_Identity=20.8888888888889, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789593, Length=232, Percent_Identity=25.8620689655172, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789962, Length=217, Percent_Identity=24.8847926267281, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789586, Length=212, Percent_Identity=26.4150943396226, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787089, Length=229, Percent_Identity=24.4541484716157, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786975, Length=232, Percent_Identity=21.9827586206897, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788897, Length=233, Percent_Identity=22.7467811158798, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787758, Length=212, Percent_Identity=23.5849056603774, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081834, Length=214, Percent_Identity=23.8317757009346, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788002, Length=218, Percent_Identity=22.0183486238532, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786398, Length=224, Percent_Identity=23.6607142857143, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787112, Length=230, Percent_Identity=23.4782608695652, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787041, Length=156, Percent_Identity=24.3589743589744, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787182, Length=193, Percent_Identity=24.8704663212435, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1789891, Length=195, Percent_Identity=25.6410256410256, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790525, Length=193, Percent_Identity=26.4248704663212, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790190, Length=220, Percent_Identity=23.6363636363636, Blast_Score=61, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=199, Percent_Identity=29.1457286432161, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115534520, Length=233, Percent_Identity=25.3218884120172, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17543740, Length=229, Percent_Identity=24.8908296943231, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565586, Length=217, Percent_Identity=26.7281105990783, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17555800, Length=196, Percent_Identity=25.5102040816327, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71988343, Length=236, Percent_Identity=22.8813559322034, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=245, Percent_Identity=20.4081632653061, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=232, Percent_Identity=23.7068965517241, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322640, Length=239, Percent_Identity=24.6861924686192, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45552337, Length=225, Percent_Identity=28.4444444444444, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45552347, Length=225, Percent_Identity=28.4444444444444, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45552343, Length=225, Percent_Identity=28.4444444444444, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45552363, Length=225, Percent_Identity=28.4444444444444, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45552349, Length=225, Percent_Identity=28.4444444444444, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45552361, Length=225, Percent_Identity=28.4444444444444, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45552341, Length=225, Percent_Identity=28.4444444444444, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI45552335, Length=225, Percent_Identity=28.4444444444444, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45552353, Length=225, Percent_Identity=28.4444444444444, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45552359, Length=225, Percent_Identity=28.4444444444444, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45550972, Length=225, Percent_Identity=28.4444444444444, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45552345, Length=225, Percent_Identity=28.4444444444444, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45552339, Length=201, Percent_Identity=29.8507462686567, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45552357, Length=201, Percent_Identity=29.3532338308458, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45552355, Length=201, Percent_Identity=29.3532338308458, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45552351, Length=201, Percent_Identity=29.8507462686567, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24583969, Length=225, Percent_Identity=28.4444444444444, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24582014, Length=227, Percent_Identity=23.3480176211454, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582012, Length=227, Percent_Identity=23.3480176211454, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574259, Length=221, Percent_Identity=28.0542986425339, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221500365, Length=183, Percent_Identity=27.8688524590164, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI116007184, Length=183, Percent_Identity=27.8688524590164, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28571209, Length=220, Percent_Identity=26.3636363636364, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI85725262, Length=186, Percent_Identity=29.5698924731183, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28574150, Length=203, Percent_Identity=25.615763546798, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI116007328, Length=203, Percent_Identity=25.615763546798, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI281362751, Length=199, Percent_Identity=27.1356783919598, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI85726357, Length=217, Percent_Identity=22.5806451612903, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650853, Length=197, Percent_Identity=26.3959390862944, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24650855, Length=197, Percent_Identity=26.3959390862944, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017882
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26616; Mature: 26485

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHINVEKKSIFAKKLSSVNNCILKIENLTLSYGNKKVLDNINISVQRGDIVTILGPNGG
CCCCCCHHHHHHHHHHHHHCEEEEEEEEEEEECCCEEEEECCEEEEECCCEEEEECCCCC
GKTSLVKAVAGINKGFIGSIVFADNIKISYMPQNFSIGNLMPITVESFLFNSSSKKLKKN
CHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCCCCCCEEHEEHHHHHCCCCCHHHHCC
QPIVTEAIELVGIGNILKNQVLEISAGQTQLLLLARCLISESDLIILDEPVSAMDINARS
CCHHHHHHHHHCCCHHHHCCEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCEEECCHHH
KFYDIINKIAKERSVSILMTSHDLNSALPSSDYIICINNTIYYQGKPDEIMEINEIFGSY
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEECCEEEECCCCHHHHHHHHHHHHH
AAK
CCC
>Mature Secondary Structure 
SHINVEKKSIFAKKLSSVNNCILKIENLTLSYGNKKVLDNINISVQRGDIVTILGPNGG
CCCCCHHHHHHHHHHHHHCEEEEEEEEEEEECCCEEEEECCEEEEECCCEEEEECCCCC
GKTSLVKAVAGINKGFIGSIVFADNIKISYMPQNFSIGNLMPITVESFLFNSSSKKLKKN
CHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCCCCCCEEHEEHHHHHCCCCCHHHHCC
QPIVTEAIELVGIGNILKNQVLEISAGQTQLLLLARCLISESDLIILDEPVSAMDINARS
CCHHHHHHHHHCCCHHHHCCEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCEEECCHHH
KFYDIINKIAKERSVSILMTSHDLNSALPSSDYIICINNTIYYQGKPDEIMEINEIFGSY
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEECCEEEECCCCHHHHHHHHHHHHH
AAK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA