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The map label for this gene is fabH [H]

Identifier: 189499167

GI number: 189499167

Start: 177678

End: 178664

Strand: Reverse

Name: fabH [H]

Synonym: Cphamn1_0182

Alternate gene names: 189499167

Gene position: 178664-177678 (Counterclockwise)

Preceding gene: 189499168

Following gene: 189499166

Centisome position: 6.53

GC content: 50.46

Gene sequence:

>987_bases
ATGAAAGCTGTAATCACTTCGACTGCGAAATACCTTCCTGAGAGTATACTGAGCAACAAGGATCTGGAGAAAATACTTGA
CACCAATGATGAGTGGATTCGCTCGCGGACTGGAATCGGAGAACGGCGGATTTTAAAAGACCCGGACAAAGCAACGTCAT
ATCTGTGTACCGGGGTTGCACAGCGGATCCTTGAAAAAAGAGGCATCACTGCTGATGAACTTGACCTTATCATTGTAGCG
ACGATGACTCCCGACATGGTCTTTCCGTCAACGGCCTGTCTTGTCCAGAAAAATATTCAGGCGATGAATGCATGGGCTTT
CGACCTCTCCGGAGCATGCTCAGGCTTTCTTTATGCACTCAATACCGGTGCACAGTTCATCGCTGCCGGAACACACAAAA
AGGTGCTTGTTATAGGCGGAGAAAAGATGTCGTCGATCATGGACTACACCGACAGAACAACCAGCGTTCTTTTCGGCGAC
GGTGCTGCCGGCGTGCTTCTTGAACCAGGGCAAGATGAGAAGCATGGTCTCATCGACGCCAGACTGTATTCAGACGGCAG
AGGCGGAGATAACCTCTGTATGCCTGCAGGCGGCAGCCTGCGACCGGCAACACATGAGACGATTGACGCAAAGCTTCACT
ATCTCCAGCAGGACGGCCCGCAGGTATTCAAAGCTGCTGTGGTCGCTATGGCCGAGGTTGCTGCCGAAGTCATGGAAAGG
AACAGGCTGACCAGTGACGATATTGATTTCCTCATCCCGCACCAGGCAAATAACAGAATTATTCAGGCAACTGCTGAGCG
CATGCATCTCGACCAGAAAAAGGTCGCGAAAAATATCGAACACTACGGCAACACATCTGCAGCAACCATACCGATCTGTC
TTGCAGAACTCGATGAAGCAGGAAAGCTGCATACCGGCAGCAACCTTATACTTGTCAGCTTCGGAGCCGGATACACGTGG
GGAAGTATTTACCTTAAATGGCAGTAA

Upstream 100 bases:

>100_bases
TAGCCGGAAATATCCAACCTCCCGGATCCTGTTATCCCTGATCACGGCGTCAGTGTCCCCGTGATCAGGGAGTGTCCTTA
TTAGTTTAATACCATCATTT

Downstream 100 bases:

>100_bases
TAACAATCTCTTACTGAAACAGAAGAACAAACTTCATGAAAGCATTTGTATTCCCCGGTCAGGGCTCACAGTATTGCGGC
ATGGCCAAAGAGATCTATGA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKAVITSTAKYLPESILSNKDLEKILDTNDEWIRSRTGIGERRILKDPDKATSYLCTGVAQRILEKRGITADELDLIIVA
TMTPDMVFPSTACLVQKNIQAMNAWAFDLSGACSGFLYALNTGAQFIAAGTHKKVLVIGGEKMSSIMDYTDRTTSVLFGD
GAAGVLLEPGQDEKHGLIDARLYSDGRGGDNLCMPAGGSLRPATHETIDAKLHYLQQDGPQVFKAAVVAMAEVAAEVMER
NRLTSDDIDFLIPHQANNRIIQATAERMHLDQKKVAKNIEHYGNTSAATIPICLAELDEAGKLHTGSNLILVSFGAGYTW
GSIYLKWQ

Sequences:

>Translated_328_residues
MKAVITSTAKYLPESILSNKDLEKILDTNDEWIRSRTGIGERRILKDPDKATSYLCTGVAQRILEKRGITADELDLIIVA
TMTPDMVFPSTACLVQKNIQAMNAWAFDLSGACSGFLYALNTGAQFIAAGTHKKVLVIGGEKMSSIMDYTDRTTSVLFGD
GAAGVLLEPGQDEKHGLIDARLYSDGRGGDNLCMPAGGSLRPATHETIDAKLHYLQQDGPQVFKAAVVAMAEVAAEVMER
NRLTSDDIDFLIPHQANNRIIQATAERMHLDQKKVAKNIEHYGNTSAATIPICLAELDEAGKLHTGSNLILVSFGAGYTW
GSIYLKWQ
>Mature_328_residues
MKAVITSTAKYLPESILSNKDLEKILDTNDEWIRSRTGIGERRILKDPDKATSYLCTGVAQRILEKRGITADELDLIIVA
TMTPDMVFPSTACLVQKNIQAMNAWAFDLSGACSGFLYALNTGAQFIAAGTHKKVLVIGGEKMSSIMDYTDRTTSVLFGD
GAAGVLLEPGQDEKHGLIDARLYSDGRGGDNLCMPAGGSLRPATHETIDAKLHYLQQDGPQVFKAAVVAMAEVAAEVMER
NRLTSDDIDFLIPHQANNRIIQATAERMHLDQKKVAKNIEHYGNTSAATIPICLAELDEAGKLHTGSNLILVSFGAGYTW
GSIYLKWQ

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=327, Percent_Identity=38.5321100917431, Blast_Score=239, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35704; Mature: 35704

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVITSTAKYLPESILSNKDLEKILDTNDEWIRSRTGIGERRILKDPDKATSYLCTGVA
CCCEEHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
QRILEKRGITADELDLIIVATMTPDMVFPSTACLVQKNIQAMNAWAFDLSGACSGFLYAL
HHHHHHCCCCHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCEEEEE
NTGAQFIAAGTHKKVLVIGGEKMSSIMDYTDRTTSVLFGDGAAGVLLEPGQDEKHGLIDA
CCCCEEEEECCCCEEEEECCHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCCEEEE
RLYSDGRGGDNLCMPAGGSLRPATHETIDAKLHYLQQDGPQVFKAAVVAMAEVAAEVMER
EEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
NRLTSDDIDFLIPHQANNRIIQATAERMHLDQKKVAKNIEHYGNTSAATIPICLAELDEA
CCCCCCCCCEEECCCCCCEEEEHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHEEHHCCC
GKLHTGSNLILVSFGAGYTWGSIYLKWQ
CCEECCCCEEEEEECCCCEEEEEEEEEC
>Mature Secondary Structure
MKAVITSTAKYLPESILSNKDLEKILDTNDEWIRSRTGIGERRILKDPDKATSYLCTGVA
CCCEEHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
QRILEKRGITADELDLIIVATMTPDMVFPSTACLVQKNIQAMNAWAFDLSGACSGFLYAL
HHHHHHCCCCHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHEEEEECCCCCCCEEEEE
NTGAQFIAAGTHKKVLVIGGEKMSSIMDYTDRTTSVLFGDGAAGVLLEPGQDEKHGLIDA
CCCCEEEEECCCCEEEEECCHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCCEEEE
RLYSDGRGGDNLCMPAGGSLRPATHETIDAKLHYLQQDGPQVFKAAVVAMAEVAAEVMER
EEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
NRLTSDDIDFLIPHQANNRIIQATAERMHLDQKKVAKNIEHYGNTSAATIPICLAELDEA
CCCCCCCCCEEECCCCCCEEEEHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHEEHHCCC
GKLHTGSNLILVSFGAGYTWGSIYLKWQ
CCEECCCCEEEEEECCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]