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The map label for this gene is fabD [H]

Identifier: 189499166

GI number: 189499166

Start: 176731

End: 177642

Strand: Reverse

Name: fabD [H]

Synonym: Cphamn1_0181

Alternate gene names: 189499166

Gene position: 177642-176731 (Counterclockwise)

Preceding gene: 189499167

Following gene: 189499165

Centisome position: 6.49

GC content: 53.07

Gene sequence:

>912_bases
ATGAAAGCATTTGTATTCCCCGGTCAGGGCTCACAGTATTGCGGCATGGCCAAAGAGATCTATGACCGGTATCCTGAAGC
CCGTTCCCTGATGGACAGGGCTGACGAGATCCTTGGCTATTCTATTACCGACATCATGTTCAATGGAAGTGAAGATGATC
TTCGCCAGACACGCTACACACAGCCTGCGATCTTTCTGCACAGCATCGCGGTCGCGAAACTGCTCGGAGACAATCAGGCC
GGCATGACCGCGGGACACAGTCTGGGGGAGTACACCGCGCTTTGTTACGCTGACGCGATGAGTTTTGACGACGCGATACA
CATTGTCGCAAAAAGGGGTGAACTGATGCAGAACGCAGGAACGATAAACCCCGGCACCATGGCCGCAGTGATAGGCATGA
AGGATACTGATCTTGAAAATCTTCTTGCTGAAGCAGAGACAGAGGGAATTGTCCAGGCCGCAAATTTCAACTCACCGGGA
CAGGTGGTTATTTCAGGGGATATCGATGCCGTCAGAAAAGCTGTTGAACTGGCTCCGTCTAAAGGAGCGCGAATGGCCAA
AGAGCTTGTCGTCTCCGGCGCGTTTCACTCCCCTCTCATGAAACCGGCAGAGGAAGAGCTGAAAGCCAGCCTTGACGCAA
TCACCATTAATGATGCCCGGATACCTGTCTGTATGAACGTCGTGGCACAGCCGGTCAGGCGAAAAGAAGAGATACGCAAC
AACCTCGTACTGCAGCTTACCAGCTCCGTCAAATGGCAGCAGTCGGTTGAAGCGATGATTGCCGAAGGGGTCACGTCATT
TGTCGAAACCGGCCCGCAGAAGGTTCTTCAGGGGCTGATCAAGAGAATCGACCGCTCAGTAACCATTGACGGCGTAGACA
CCGCAGACCAGATTGCACAGACACTGTCATAG

Upstream 100 bases:

>100_bases
ACCTTATACTTGTCAGCTTCGGAGCCGGATACACGTGGGGAAGTATTTACCTTAAATGGCAGTAATAACAATCTCTTACT
GAAACAGAAGAACAAACTTC

Downstream 100 bases:

>100_bases
TAGTAACAACGAGAAAATAAATTATACCCTATGTTTAAAGGCAAAACCGCCGTTATAACAGGTGCCGCCAGAGGAATCGG
TCAGGCAATCGCAGTAAACC

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKAFVFPGQGSQYCGMAKEIYDRYPEARSLMDRADEILGYSITDIMFNGSEDDLRQTRYTQPAIFLHSIAVAKLLGDNQA
GMTAGHSLGEYTALCYADAMSFDDAIHIVAKRGELMQNAGTINPGTMAAVIGMKDTDLENLLAEAETEGIVQAANFNSPG
QVVISGDIDAVRKAVELAPSKGARMAKELVVSGAFHSPLMKPAEEELKASLDAITINDARIPVCMNVVAQPVRRKEEIRN
NLVLQLTSSVKWQQSVEAMIAEGVTSFVETGPQKVLQGLIKRIDRSVTIDGVDTADQIAQTLS

Sequences:

>Translated_303_residues
MKAFVFPGQGSQYCGMAKEIYDRYPEARSLMDRADEILGYSITDIMFNGSEDDLRQTRYTQPAIFLHSIAVAKLLGDNQA
GMTAGHSLGEYTALCYADAMSFDDAIHIVAKRGELMQNAGTINPGTMAAVIGMKDTDLENLLAEAETEGIVQAANFNSPG
QVVISGDIDAVRKAVELAPSKGARMAKELVVSGAFHSPLMKPAEEELKASLDAITINDARIPVCMNVVAQPVRRKEEIRN
NLVLQLTSSVKWQQSVEAMIAEGVTSFVETGPQKVLQGLIKRIDRSVTIDGVDTADQIAQTLS
>Mature_303_residues
MKAFVFPGQGSQYCGMAKEIYDRYPEARSLMDRADEILGYSITDIMFNGSEDDLRQTRYTQPAIFLHSIAVAKLLGDNQA
GMTAGHSLGEYTALCYADAMSFDDAIHIVAKRGELMQNAGTINPGTMAAVIGMKDTDLENLLAEAETEGIVQAANFNSPG
QVVISGDIDAVRKAVELAPSKGARMAKELVVSGAFHSPLMKPAEEELKASLDAITINDARIPVCMNVVAQPVRRKEEIRN
NLVLQLTSSVKWQQSVEAMIAEGVTSFVETGPQKVLQGLIKRIDRSVTIDGVDTADQIAQTLS

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=299, Percent_Identity=32.7759197324415, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=37.3831775700935, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787334, Length=303, Percent_Identity=40.5940594059406, Blast_Score=202, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI71984332, Length=290, Percent_Identity=30, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=288, Percent_Identity=30.2083333333333, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24665753, Length=298, Percent_Identity=34.2281879194631, Blast_Score=159, Evalue=3e-39,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32785; Mature: 32785

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFVFPGQGSQYCGMAKEIYDRYPEARSLMDRADEILGYSITDIMFNGSEDDLRQTRYT
CCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHEECCCHHHHHHHHCC
QPAIFLHSIAVAKLLGDNQAGMTAGHSLGEYTALCYADAMSFDDAIHIVAKRGELMQNAG
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
TINPGTMAAVIGMKDTDLENLLAEAETEGIVQAANFNSPGQVVISGDIDAVRKAVELAPS
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCCCCEEEECCHHHHHHHHHHCCC
KGARMAKELVVSGAFHSPLMKPAEEELKASLDAITINDARIPVCMNVVAQPVRRKEEIRN
CHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHC
NLVLQLTSSVKWQQSVEAMIAEGVTSFVETGPQKVLQGLIKRIDRSVTIDGVDTADQIAQ
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCHHHHHH
TLS
HCC
>Mature Secondary Structure
MKAFVFPGQGSQYCGMAKEIYDRYPEARSLMDRADEILGYSITDIMFNGSEDDLRQTRYT
CCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHEECCCHHHHHHHHCC
QPAIFLHSIAVAKLLGDNQAGMTAGHSLGEYTALCYADAMSFDDAIHIVAKRGELMQNAG
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
TINPGTMAAVIGMKDTDLENLLAEAETEGIVQAANFNSPGQVVISGDIDAVRKAVELAPS
CCCCCCEEEEECCCCCCHHHHHHHHHHCCCEEECCCCCCCCEEEECCHHHHHHHHHHCCC
KGARMAKELVVSGAFHSPLMKPAEEELKASLDAITINDARIPVCMNVVAQPVRRKEEIRN
CHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHHHHHHHC
NLVLQLTSSVKWQQSVEAMIAEGVTSFVETGPQKVLQGLIKRIDRSVTIDGVDTADQIAQ
CEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEECCCCCHHHHHH
TLS
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]