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The map label for this gene is yaeL [C]

Identifier: 189499091

GI number: 189499091

Start: 89382

End: 90743

Strand: Reverse

Name: yaeL [C]

Synonym: Cphamn1_0097

Alternate gene names: 189499091

Gene position: 90743-89382 (Counterclockwise)

Preceding gene: 189499092

Following gene: 189499090

Centisome position: 3.32

GC content: 50.66

Gene sequence:

>1362_bases
ATGGACTTTATCAGTACGACGTTTTACTTTATTTTAGCGATTTTCGTTCTTGTCACCGCTCACGAGCTTGGTCATTTCCT
TACGGCCAAACTTTTCGGTATGCGGGTGGACAAATTTTATATCGGATTTGATTTCTACAATCTCCGTTTCTGGAAGAAGA
AAATCGGAGAAACCGAATACGGCATCGGTGTGTTCCCGCTTGGAGGATATGTGAAAATCGCGGGAATGGTCGATGAGAGC
CTCGATACCGATTTCCAGAAGAGTGAGCCTGAGCCCTGGGAGTTCAGGGCTAAACCGGTCTGGCAACGCCTCATCGTTCT
CGCCGGCGGCGTGACGATGAACATGATTCTCGCTGCCGCGATCTTCATCGGAATGGCCGCGGTTTTCGGCGAAAGCAGAA
CGTCCGCCGTCAACCCCGCCTATGTGGAAGACGGTTCGGTCTATGCCTCCATGGGCATGCAGACTGGCGACCGCTTTCTT
GCCGTCAACGGCAAACCTGTCGGCTTCTGGGAAGAGGTGCTTTCACCCCGGAACTTTGCGGGAAACACCCTGAGCTATAC
CATAGCACGCGATGGAGAGCGAAAAAACCTGCAAGCCCCGCCGGACATTCTTACCCGGATCAACGATAATAAGGCATTGG
GCATTCGCCCCCTTATGGAACCGGTAATAGATCAGGTGCTTGAAGACGAACCCGCAGACAAAGCCGGTCTGAAGTCGGGA
GCGCTCATCACAGCCATCAACGAAACGCCGGTCTATGACTGGACAGAAGTTGTCACTCTCATCTCTGATAATCCCGGCAA
GACAATCAACGTCACATGGAAGTACCTTGAAAATCCTTCCGGAAGCACAGTGGATGTTTCGAAAATCAGAGAACTCGGTC
AGCAGACTATTTCCGAGGTTACCCCTGCAGCAACGGGAAAAATAGGCATCTCCCTTCTTCAGACACTTACCATTGACCAC
CGCCGTCTCAACCCTATCGAAGCAACAGTCTATGGTCTGGAGCAGACCTGGAACATGACCGTCACAACAGTCAACGGCTT
TGGGAAAATCATTTCAGGAAAGGAGGATTTCCGGAAATCACTTGGCGGCCCGATAAAGATCGCGAAAATTGCCAACCAGA
GTGCCGAACAGGGCCTGGGCAGTTTTCTCTACTTCATGGCGCTTCTGTCGATTTCTCTCGCCTTCATCAATATCCTGCCT
GTTCCGGCTCTTGACGGCGGTCAGTTTCTCCTTAACGCCATAGAAGGCATTATAGGCCGCGAGATACCATTTGAGCTCAA
AATGAGAATTCAACAGGTCGGCATGGCTCTGCTTCTGACGCTCTTTTTATTCATTATCATCAATGATATTATCAACCCCT
GA

Upstream 100 bases:

>100_bases
CAGGTGGGCCCGTGATACCGCGAAAACAATGACGAATTAAGAGATAGGTGCCCCTCAGGGGCTTTCGACACAGTTTGTAG
AGAAGGAAACAGAGAATATT

Downstream 100 bases:

>100_bases
TGAAGAGGGGAACGGAGTAAAGGCAGACTATGCTTGAAAAACTTGAAGCGTTAAAGGACAAATACCTTCGGCTTGAAGAA
CAGCTTTCCGATCCGGAAAT

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MDFISTTFYFILAIFVLVTAHELGHFLTAKLFGMRVDKFYIGFDFYNLRFWKKKIGETEYGIGVFPLGGYVKIAGMVDES
LDTDFQKSEPEPWEFRAKPVWQRLIVLAGGVTMNMILAAAIFIGMAAVFGESRTSAVNPAYVEDGSVYASMGMQTGDRFL
AVNGKPVGFWEEVLSPRNFAGNTLSYTIARDGERKNLQAPPDILTRINDNKALGIRPLMEPVIDQVLEDEPADKAGLKSG
ALITAINETPVYDWTEVVTLISDNPGKTINVTWKYLENPSGSTVDVSKIRELGQQTISEVTPAATGKIGISLLQTLTIDH
RRLNPIEATVYGLEQTWNMTVTTVNGFGKIISGKEDFRKSLGGPIKIAKIANQSAEQGLGSFLYFMALLSISLAFINILP
VPALDGGQFLLNAIEGIIGREIPFELKMRIQQVGMALLLTLFLFIIINDIINP

Sequences:

>Translated_453_residues
MDFISTTFYFILAIFVLVTAHELGHFLTAKLFGMRVDKFYIGFDFYNLRFWKKKIGETEYGIGVFPLGGYVKIAGMVDES
LDTDFQKSEPEPWEFRAKPVWQRLIVLAGGVTMNMILAAAIFIGMAAVFGESRTSAVNPAYVEDGSVYASMGMQTGDRFL
AVNGKPVGFWEEVLSPRNFAGNTLSYTIARDGERKNLQAPPDILTRINDNKALGIRPLMEPVIDQVLEDEPADKAGLKSG
ALITAINETPVYDWTEVVTLISDNPGKTINVTWKYLENPSGSTVDVSKIRELGQQTISEVTPAATGKIGISLLQTLTIDH
RRLNPIEATVYGLEQTWNMTVTTVNGFGKIISGKEDFRKSLGGPIKIAKIANQSAEQGLGSFLYFMALLSISLAFINILP
VPALDGGQFLLNAIEGIIGREIPFELKMRIQQVGMALLLTLFLFIIINDIINP
>Mature_453_residues
MDFISTTFYFILAIFVLVTAHELGHFLTAKLFGMRVDKFYIGFDFYNLRFWKKKIGETEYGIGVFPLGGYVKIAGMVDES
LDTDFQKSEPEPWEFRAKPVWQRLIVLAGGVTMNMILAAAIFIGMAAVFGESRTSAVNPAYVEDGSVYASMGMQTGDRFL
AVNGKPVGFWEEVLSPRNFAGNTLSYTIARDGERKNLQAPPDILTRINDNKALGIRPLMEPVIDQVLEDEPADKAGLKSG
ALITAINETPVYDWTEVVTLISDNPGKTINVTWKYLENPSGSTVDVSKIRELGQQTISEVTPAATGKIGISLLQTLTIDH
RRLNPIEATVYGLEQTWNMTVTTVNGFGKIISGKEDFRKSLGGPIKIAKIANQSAEQGLGSFLYFMALLSISLAFINILP
VPALDGGQFLLNAIEGIIGREIPFELKMRIQQVGMALLLTLFLFIIINDIINP

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=452, Percent_Identity=32.3008849557522, Blast_Score=171, Evalue=7e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49954; Mature: 49954

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFISTTFYFILAIFVLVTAHELGHFLTAKLFGMRVDKFYIGFDFYNLRFWKKKIGETEY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEHHHHHHHHHCCCCCC
GIGVFPLGGYVKIAGMVDESLDTDFQKSEPEPWEFRAKPVWQRLIVLAGGVTMNMILAAA
CEEEEECCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHH
IFIGMAAVFGESRTSAVNPAYVEDGSVYASMGMQTGDRFLAVNGKPVGFWEEVLSPRNFA
HHHHHHHHHCCCCCCCCCCCEECCCCEEEECCCCCCCEEEEECCCCCCHHHHHCCCCCCC
GNTLSYTIARDGERKNLQAPPDILTRINDNKALGIRPLMEPVIDQVLEDEPADKAGLKSG
CCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
ALITAINETPVYDWTEVVTLISDNPGKTINVTWKYLENPSGSTVDVSKIRELGQQTISEV
CEEEEECCCCCCCHHHHHEEEECCCCCEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHC
TPAATGKIGISLLQTLTIDHRRLNPIEATVYGLEQTWNMTVTTVNGFGKIISGKEDFRKS
CCCCCCHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCEEEEEECCCHHHCCCHHHHHHH
LGGPIKIAKIANQSAEQGLGSFLYFMALLSISLAFINILPVPALDGGQFLLNAIEGIIGR
CCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
EIPFELKMRIQQVGMALLLTLFLFIIINDIINP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFISTTFYFILAIFVLVTAHELGHFLTAKLFGMRVDKFYIGFDFYNLRFWKKKIGETEY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEHHHHHHHHHCCCCCC
GIGVFPLGGYVKIAGMVDESLDTDFQKSEPEPWEFRAKPVWQRLIVLAGGVTMNMILAAA
CEEEEECCCEEEEEEHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHH
IFIGMAAVFGESRTSAVNPAYVEDGSVYASMGMQTGDRFLAVNGKPVGFWEEVLSPRNFA
HHHHHHHHHCCCCCCCCCCCEECCCCEEEECCCCCCCEEEEECCCCCCHHHHHCCCCCCC
GNTLSYTIARDGERKNLQAPPDILTRINDNKALGIRPLMEPVIDQVLEDEPADKAGLKSG
CCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
ALITAINETPVYDWTEVVTLISDNPGKTINVTWKYLENPSGSTVDVSKIRELGQQTISEV
CEEEEECCCCCCCHHHHHEEEECCCCCEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHC
TPAATGKIGISLLQTLTIDHRRLNPIEATVYGLEQTWNMTVTTVNGFGKIISGKEDFRKS
CCCCCCHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCEEEEEECCCHHHCCCHHHHHHH
LGGPIKIAKIANQSAEQGLGSFLYFMALLSISLAFINILPVPALDGGQFLLNAIEGIIGR
CCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
EIPFELKMRIQQVGMALLLTLFLFIIINDIINP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]