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The map label for this gene is aroE [H]

Identifier: 189353856

GI number: 189353856

Start: 2162439

End: 2163308

Strand: Reverse

Name: aroE [H]

Synonym: BMULJ_05108

Alternate gene names: 189353856

Gene position: 2163308-2162439 (Counterclockwise)

Preceding gene: 189353857

Following gene: 189353855

Centisome position: 87.47

GC content: 70.23

Gene sequence:

>870_bases
ATGAATCGTCCGTCGTTTCTGATCGGCCTGATCGGCCAGGGCATCGGCGGATCGCTGTCGCCCGCGATGCATGAAGAAGA
AGGATTCCGGCAGGGTTTCGGCTACGTGTACCGACGCATCGATCTCGACGCGCTCGGGCTGAGCGTCGACGCACTGCCCG
CGCTGCTCGATGCCGCGCAGCGCATGGGATACAACGGCCTGAACATCACGCATCCGTGCAAGCAGCGCGTGATCGAGCAC
CTCGACGAACTGTCCGACGATGCGCGTGCGCTCGGCGCGGTCAACACGGTGCTGTTCCGCGACGGCCGCCGGATCGGCCA
CAACACCGACTGGTCCGGTTTTGCGAAATCGTTCCGGCGCGGGCTGCCGGGCGCGTCGCTCGAGCGTGTCGTGCAGCTCG
GCGCGGGCGGCGCGGGCGCGGCCGTCGCGCATGCGGCGCTGCAGATGGGCGCGGCCGAACTGACGTTGTTCGACGTCGAC
GCCACGCGCGCCGCGTCGCTCGCCGGCGAACTGCAGCAGCGTTTCCCGGCTGCGCGCGTCGTGGCGGGCGGCACGCCCTC
CGGCGATGCGCTGGCGGCCGCGATGCGCGCGGCGACCGGCCTGATCCACGCGACGCCGACCGGCATGATCAAGCATCCCG
GCCTGCCGCTGCCCGCCGAACTGCTGCACGCCGGCATGTGGGTGGCCGACATCGTGTATTTCCCGCTCGAAACCGAACTG
ATCCGCGCGGCACGCGCGGCGGGCTGCGCGACGCTGCCCGGCGGCGGCATGGCCGTCTACCAGGCGGTCGATGCGTTCGA
ACTCTTCACCGGACGCACGCCCGACGCCGAGCGGATGTTCGAGCACTTTCAGTCGCTCGTCGCGCGCTGA

Upstream 100 bases:

>100_bases
TGGCCGCGCTCGCCGAAGCCGTGATCTGCGGCTGCGGCACCGACGGCTACATCTTCGCGCTGCAGCGTATGGCGACGCTT
CTTGCGCGGGGAGCCGCGCG

Downstream 100 bases:

>100_bases
CCCATCGACATAAAGAGAGACCAGGAGACGACCATGCAGCACTCCACCCGTACGAGCGCCGCGCCGGCGCAGGCCGCCGC
CGGCGCGGCCCGGCGCACGT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MNRPSFLIGLIGQGIGGSLSPAMHEEEGFRQGFGYVYRRIDLDALGLSVDALPALLDAAQRMGYNGLNITHPCKQRVIEH
LDELSDDARALGAVNTVLFRDGRRIGHNTDWSGFAKSFRRGLPGASLERVVQLGAGGAGAAVAHAALQMGAAELTLFDVD
ATRAASLAGELQQRFPAARVVAGGTPSGDALAAAMRAATGLIHATPTGMIKHPGLPLPAELLHAGMWVADIVYFPLETEL
IRAARAAGCATLPGGGMAVYQAVDAFELFTGRTPDAERMFEHFQSLVAR

Sequences:

>Translated_289_residues
MNRPSFLIGLIGQGIGGSLSPAMHEEEGFRQGFGYVYRRIDLDALGLSVDALPALLDAAQRMGYNGLNITHPCKQRVIEH
LDELSDDARALGAVNTVLFRDGRRIGHNTDWSGFAKSFRRGLPGASLERVVQLGAGGAGAAVAHAALQMGAAELTLFDVD
ATRAASLAGELQQRFPAARVVAGGTPSGDALAAAMRAATGLIHATPTGMIKHPGLPLPAELLHAGMWVADIVYFPLETEL
IRAARAAGCATLPGGGMAVYQAVDAFELFTGRTPDAERMFEHFQSLVAR
>Mature_289_residues
MNRPSFLIGLIGQGIGGSLSPAMHEEEGFRQGFGYVYRRIDLDALGLSVDALPALLDAAQRMGYNGLNITHPCKQRVIEH
LDELSDDARALGAVNTVLFRDGRRIGHNTDWSGFAKSFRRGLPGASLERVVQLGAGGAGAAVAHAALQMGAAELTLFDVD
ATRAASLAGELQQRFPAARVVAGGTPSGDALAAAMRAATGLIHATPTGMIKHPGLPLPAELLHAGMWVADIVYFPLETEL
IRAARAAGCATLPGGGMAVYQAVDAFELFTGRTPDAERMFEHFQSLVAR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=271, Percent_Identity=30.6273062730627, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789675, Length=286, Percent_Identity=29.7202797202797, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320332, Length=294, Percent_Identity=26.1904761904762, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR013708
- InterPro:   IPR022893 [H]

Pfam domain/function: PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 30482; Mature: 30482

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRPSFLIGLIGQGIGGSLSPAMHEEEGFRQGFGYVYRRIDLDALGLSVDALPALLDAAQ
CCCCCEEHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHH
RMGYNGLNITHPCKQRVIEHLDELSDDARALGAVNTVLFRDGRRIGHNTDWSGFAKSFRR
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
GLPGASLERVVQLGAGGAGAAVAHAALQMGAAELTLFDVDATRAASLAGELQQRFPAARV
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHEEEEECCHHHHHHHHHHHHHHCCHHEE
VAGGTPSGDALAAAMRAATGLIHATPTGMIKHPGLPLPAELLHAGMWVADIVYFPLETEL
EECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHCCCHHHH
IRAARAAGCATLPGGGMAVYQAVDAFELFTGRTPDAERMFEHFQSLVAR
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRPSFLIGLIGQGIGGSLSPAMHEEEGFRQGFGYVYRRIDLDALGLSVDALPALLDAAQ
CCCCCEEHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHH
RMGYNGLNITHPCKQRVIEHLDELSDDARALGAVNTVLFRDGRRIGHNTDWSGFAKSFRR
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
GLPGASLERVVQLGAGGAGAAVAHAALQMGAAELTLFDVDATRAASLAGELQQRFPAARV
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHEEEEECCHHHHHHHHHHHHHHCCHHEE
VAGGTPSGDALAAAMRAATGLIHATPTGMIKHPGLPLPAELLHAGMWVADIVYFPLETEL
EECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHCCCHHHH
IRAARAAGCATLPGGGMAVYQAVDAFELFTGRTPDAERMFEHFQSLVAR
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12692562; 11572948 [H]