Click here to switch to the map view.

The map label for this gene is dgoT [H]

Identifier: 189353855

GI number: 189353855

Start: 2161071

End: 2162405

Strand: Reverse

Name: dgoT [H]

Synonym: BMULJ_05107

Alternate gene names: 189353855

Gene position: 2162405-2161071 (Counterclockwise)

Preceding gene: 189353856

Following gene: 189353853

Centisome position: 87.43

GC content: 67.19

Gene sequence:

>1335_bases
ATGCAGCACTCCACCCGTACGAGCGCCGCGCCGGCGCAGGCCGCCGCCGGCGCGGCCCGGCGCACGTCGGCGCGCTACAA
GATCCTCGCGCTGCTCGCGATCGGCACGATGATCAACTATCTCGACCGCACCGTGCTCGGCGTGGCGGCGCCGCAGCTGA
CGAAGGAGCTCGGCATCAACGCGGCAGTAATGGGCATCATGTTCTCGGCGTTCTCGTGGACGTACGTGGTCGCGCAGGTG
CCGGGCGGTCTCGTTCTCGACCGCTTGGGCAGCAAGGTCACCTATTACTGGTCGATGACGCTGTGGTCGCTCTGCACGTT
CCTGCAGGGCTTCGTGCCGGGCGTCGCGACGCTGCTCGCATGCCGGCTCGGCCTCGGCCTCAGCGAGGCGCCGTGCTTTC
CGACCAACAGCCGCGTGGTCGCGACGTGGTTCCCGCAGAACGAGCGCGCGATGGCGACCGGCACTTACACGGTCGGCGAA
TACATCGGCCTCGCGTTCTTCAGCCCCGTGCTGTTCGCGCTGATGGGCGCGTTCGGCTGGCGTTCGCTGTTCTGGGTCGT
CGGTGCGGCCGGCATCCTGTTCGGGCTCGTCTGGTGGAAGTTCTATCACGAGCCGCGCAATCATCCGGGCGCGAACGCCG
CGGAGCTCGCCTATATCGAGGCGGGCGGCGGTCTCGTGCACGGCGTGCGCAAGAACGACAAGCCGGCGCAGAAGGCGTTC
AGCTGGGCGATGGCCGGCCGGCTGCTCAAGAAGCGCCAGCTCGCGGGCATCTGCCTCGGCCAGTTCGCCGGCAACTCGAC
GCTCGTGTTCTTCCTGACCTGGTTCCCGACCTATCTTGCGACCGAGCGCCATATGGGCTGGCTGAAGATCGGCTTCTTCG
CGGTGATGCCGTTCATCGCCGCATCGGTCGGCGTGATGTTCGGCGGGATCTTCTCCGACTGGCTGCTGCGTCGCGGCAAG
TCCGCGAACCTCGCGCGCAAGCTGCCGATCATCGCCGGCCTGCTGCTCGCATCGACGATCATTCTCGCGAACTACGTGCA
GAGCAACGAGGCCGTGATCGCCATCATGTCGGTCGCGTTCTTCGCGCAGGGGATGGCCGCGCTCGGCTGGACGCTCGTGT
CCGACATCGCGCCGGACGGCCTGCTCGGCGTGACGGGCGGCATCTTCAACCTCGCGGCGAACCTGGCAGGCATCGTCACG
CCGCTCGTCGTCGGCTTCATCGTCGCCTCGACCGGCTCGTTCGTCGGCGCGCTCGTGTTCATCGGCGCGATCGCGTTGAT
CGGCGCGCTGTCGTACATCTTCGTCGTCGGCGACATCAAGCGGATCGAACTCTAA

Upstream 100 bases:

>100_bases
CTTCACCGGACGCACGCCCGACGCCGAGCGGATGTTCGAGCACTTTCAGTCGCTCGTCGCGCGCTGACCCATCGACATAA
AGAGAGACCAGGAGACGACC

Downstream 100 bases:

>100_bases
GCAGCGGCTCCACGCAGCAGTCGTGCATTCGCCCGGCGGCCTCCCAGGCCGCCGGGCTTTTTCATATCTTCACGCCGGTT
GCAGCGCGATGCCGAGCGAC

Product: D-galactonate transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MQHSTRTSAAPAQAAAGAARRTSARYKILALLAIGTMINYLDRTVLGVAAPQLTKELGINAAVMGIMFSAFSWTYVVAQV
PGGLVLDRLGSKVTYYWSMTLWSLCTFLQGFVPGVATLLACRLGLGLSEAPCFPTNSRVVATWFPQNERAMATGTYTVGE
YIGLAFFSPVLFALMGAFGWRSLFWVVGAAGILFGLVWWKFYHEPRNHPGANAAELAYIEAGGGLVHGVRKNDKPAQKAF
SWAMAGRLLKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMGWLKIGFFAVMPFIAASVGVMFGGIFSDWLLRRGK
SANLARKLPIIAGLLLASTIILANYVQSNEAVIAIMSVAFFAQGMAALGWTLVSDIAPDGLLGVTGGIFNLAANLAGIVT
PLVVGFIVASTGSFVGALVFIGAIALIGALSYIFVVGDIKRIEL

Sequences:

>Translated_444_residues
MQHSTRTSAAPAQAAAGAARRTSARYKILALLAIGTMINYLDRTVLGVAAPQLTKELGINAAVMGIMFSAFSWTYVVAQV
PGGLVLDRLGSKVTYYWSMTLWSLCTFLQGFVPGVATLLACRLGLGLSEAPCFPTNSRVVATWFPQNERAMATGTYTVGE
YIGLAFFSPVLFALMGAFGWRSLFWVVGAAGILFGLVWWKFYHEPRNHPGANAAELAYIEAGGGLVHGVRKNDKPAQKAF
SWAMAGRLLKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMGWLKIGFFAVMPFIAASVGVMFGGIFSDWLLRRGK
SANLARKLPIIAGLLLASTIILANYVQSNEAVIAIMSVAFFAQGMAALGWTLVSDIAPDGLLGVTGGIFNLAANLAGIVT
PLVVGFIVASTGSFVGALVFIGAIALIGALSYIFVVGDIKRIEL
>Mature_444_residues
MQHSTRTSAAPAQAAAGAARRTSARYKILALLAIGTMINYLDRTVLGVAAPQLTKELGINAAVMGIMFSAFSWTYVVAQV
PGGLVLDRLGSKVTYYWSMTLWSLCTFLQGFVPGVATLLACRLGLGLSEAPCFPTNSRVVATWFPQNERAMATGTYTVGE
YIGLAFFSPVLFALMGAFGWRSLFWVVGAAGILFGLVWWKFYHEPRNHPGANAAELAYIEAGGGLVHGVRKNDKPAQKAF
SWAMAGRLLKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMGWLKIGFFAVMPFIAASVGVMFGGIFSDWLLRRGK
SANLARKLPIIAGLLLASTIILANYVQSNEAVIAIMSVAFFAQGMAALGWTLVSDIAPDGLLGVTGGIFNLAANLAGIVT
PLVVGFIVASTGSFVGALVFIGAIALIGALSYIFVVGDIKRIEL

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9945322, Length=409, Percent_Identity=25.4278728606357, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI9966811, Length=415, Percent_Identity=25.7831325301205, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI21322234, Length=391, Percent_Identity=25.5754475703325, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI154350196, Length=414, Percent_Identity=24.1545893719807, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI148743791, Length=399, Percent_Identity=25.31328320802, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI6912666, Length=484, Percent_Identity=23.5537190082645, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4885441, Length=399, Percent_Identity=25.8145363408521, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI148728191, Length=338, Percent_Identity=26.3313609467456, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI223718438, Length=204, Percent_Identity=26.9607843137255, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI154800443, Length=329, Percent_Identity=23.7082066869301, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI5031955, Length=285, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1789152, Length=441, Percent_Identity=45.124716553288, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI87082320, Length=425, Percent_Identity=47.2941176470588, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1789515, Length=434, Percent_Identity=44.9308755760369, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI2367379, Length=443, Percent_Identity=32.0541760722348, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI2367193, Length=423, Percent_Identity=27.6595744680851, Blast_Score=137, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI115533556, Length=436, Percent_Identity=25.2293577981651, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115533554, Length=395, Percent_Identity=26.0759493670886, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17535049, Length=423, Percent_Identity=23.1678486997636, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17552542, Length=402, Percent_Identity=24.8756218905473, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71997452, Length=463, Percent_Identity=23.110151187905, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193205400, Length=252, Percent_Identity=25, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI25141341, Length=396, Percent_Identity=23.989898989899, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI25141316, Length=350, Percent_Identity=25.1428571428571, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25141318, Length=350, Percent_Identity=25.1428571428571, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI86561091, Length=295, Percent_Identity=25.4237288135593, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565914, Length=245, Percent_Identity=22.0408163265306, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI32565916, Length=245, Percent_Identity=22.0408163265306, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=410, Percent_Identity=23.9024390243902, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71991448, Length=410, Percent_Identity=23.9024390243902, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17554148, Length=403, Percent_Identity=23.8213399503722, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24654215, Length=408, Percent_Identity=25.4901960784314, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19922400, Length=408, Percent_Identity=25.4901960784314, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI45550460, Length=423, Percent_Identity=25.0591016548463, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573299, Length=408, Percent_Identity=25.2450980392157, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI62484226, Length=442, Percent_Identity=26.6968325791855, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24653727, Length=404, Percent_Identity=25.2475247524752, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24655255, Length=372, Percent_Identity=25.5376344086022, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648416, Length=427, Percent_Identity=23.4192037470726, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356189, Length=427, Percent_Identity=23.4192037470726, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24658658, Length=438, Percent_Identity=26.7123287671233, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24583789, Length=399, Percent_Identity=22.3057644110276, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641682, Length=411, Percent_Identity=24.8175182481752, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24639764, Length=399, Percent_Identity=24.0601503759398, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI20130135, Length=442, Percent_Identity=23.9819004524887, Blast_Score=85, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24655271, Length=425, Percent_Identity=24.4705882352941, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573708, Length=389, Percent_Identity=26.4781491002571, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573707, Length=389, Percent_Identity=26.4781491002571, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI20129235, Length=354, Percent_Identity=25.4237288135593, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584153, Length=398, Percent_Identity=21.8592964824121, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24580790, Length=385, Percent_Identity=23.6363636363636, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45550495, Length=434, Percent_Identity=25.1152073732719, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24658674, Length=369, Percent_Identity=24.1192411924119, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20130167, Length=368, Percent_Identity=23.0978260869565, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47419; Mature: 47419

Theoretical pI: Translated: 10.26; Mature: 10.26

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHSTRTSAAPAQAAAGAARRTSARYKILALLAIGTMINYLDRTVLGVAAPQLTKELGIN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AAVMGIMFSAFSWTYVVAQVPGGLVLDRLGSKVTYYWSMTLWSLCTFLQGFVPGVATLLA
HHHHHHHHHHHHHHHEEEECCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
CRLGLGLSEAPCFPTNSRVVATWFPQNERAMATGTYTVGEYIGLAFFSPVLFALMGAFGW
HHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RSLFWVVGAAGILFGLVWWKFYHEPRNHPGANAAELAYIEAGGGLVHGVRKNDKPAQKAF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEEECCCCEEECCCCCCCHHHHHH
SWAMAGRLLKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMGWLKIGFFAVMPFIA
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ASVGVMFGGIFSDWLLRRGKSANLARKLPIIAGLLLASTIILANYVQSNEAVIAIMSVAF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FAQGMAALGWTLVSDIAPDGLLGVTGGIFNLAANLAGIVTPLVVGFIVASTGSFVGALVF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
IGAIALIGALSYIFVVGDIKRIEL
HHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MQHSTRTSAAPAQAAAGAARRTSARYKILALLAIGTMINYLDRTVLGVAAPQLTKELGIN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
AAVMGIMFSAFSWTYVVAQVPGGLVLDRLGSKVTYYWSMTLWSLCTFLQGFVPGVATLLA
HHHHHHHHHHHHHHHEEEECCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
CRLGLGLSEAPCFPTNSRVVATWFPQNERAMATGTYTVGEYIGLAFFSPVLFALMGAFGW
HHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RSLFWVVGAAGILFGLVWWKFYHEPRNHPGANAAELAYIEAGGGLVHGVRKNDKPAQKAF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEEECCCCEEECCCCCCCHHHHHH
SWAMAGRLLKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMGWLKIGFFAVMPFIA
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ASVGVMFGGIFSDWLLRRGKSANLARKLPIIAGLLLASTIILANYVQSNEAVIAIMSVAF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
FAQGMAALGWTLVSDIAPDGLLGVTGGIFNLAANLAGIVTPLVVGFIVASTGSFVGALVF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
IGAIALIGALSYIFVVGDIKRIEL
HHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9772162; 10762278 [H]