| Definition | Burkholderia multivorans ATCC 17616 chromosome 2, complete genome. |
|---|---|
| Accession | NC_010805 |
| Length | 2,473,162 |
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The map label for this gene is fabG [H]
Identifier: 189352362
GI number: 189352362
Start: 417283
End: 418071
Strand: Direct
Name: fabG [H]
Synonym: BMULJ_03581
Alternate gene names: 189352362
Gene position: 417283-418071 (Clockwise)
Preceding gene: 189352361
Following gene: 189352363
Centisome position: 16.87
GC content: 69.46
Gene sequence:
>789_bases ATGACAGCCGTTTCGCCGCGTCTCGCCGGCAAGTGTGCGTACATCACCGGTGCCGCGGGCGGCCTCGGCCGCGCGATCGC GCGCCAGATGGTCGAGCAGGGCGCGCGTGTCTTCCTGACCGACGTCGCCGATCGCGCGGCGCTCGACGCGTTCGCAGCGG AACTCAATGCGGGCCATGCGACGCCGGTCGCGTTCGCCGCCGAGCAGGACGTGCGCGACGAAGCGCGCTGGCAGACACTG CTCGCGCAGGCCAACGACGCGATGGGCGCGTTGTCGGTGCTCGTGAACAACGCGGGCGTCGGCTCGCTCGCCGCGCCCGC GCAGATCGAACTCGACGAATGGCGGCGCGTGATGGCCGTGAACGTCGAAAGCATCGTGCTCGGCTGCAAGCATGCGCTGC CGTATCTGAGCGCGAGCCGCCCGGCGTCGATCGTCAACATCTCGTCGGTCGCCGCGTTCAAGGTCGAACCGGATTTCACC GCGTACAACGCGTCGAAGGCGGCGGTCGCGTCGCTGACGAAGTCGATCGCGATCGACTGCGCGCGGCGCGAACTCGACGT GCGCTGCAATTCGATCCATCCGGCGTTCATCCGGACCGGCATCATGGAGCCGCTGTTCCGCACGCTCGGCGAGCGCGATG CGACGCGCCGGCTCGCGCGCGGCATTCCGTTGCGCCGGCTCGGCGAACCGGACGACGTCGCGCATGCGGCCGTCTATCTC GCATCCGACGAGAGCCGTTTCATGACGGCCGCCGAACTCGTGCTCGACGGCGGGATGTGCGCGGTCTGA
Upstream 100 bases:
>100_bases GTGGCGCACCGGGCGGCGATTCGCGGCCCGGCCGCCGCGACACGCTGCGCGTCGCGGCATCGGTTCGCGACGACACTTCA CGACAGGAGCCGTTCCCATC
Downstream 100 bases:
>100_bases TGCGCACGGTACCGCGCGGCGCAATGAGCAAAAGTCCCACTAAGCGCGCATCGATTTAGGAATCGTCCTATATCTCGTGC GGGTTCGTCCATCTAAAGTG
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 2,5-DDOL dehydrogenase [H]
Number of amino acids: Translated: 262; Mature: 261
Protein sequence:
>262_residues MTAVSPRLAGKCAYITGAAGGLGRAIARQMVEQGARVFLTDVADRAALDAFAAELNAGHATPVAFAAEQDVRDEARWQTL LAQANDAMGALSVLVNNAGVGSLAAPAQIELDEWRRVMAVNVESIVLGCKHALPYLSASRPASIVNISSVAAFKVEPDFT AYNASKAAVASLTKSIAIDCARRELDVRCNSIHPAFIRTGIMEPLFRTLGERDATRRLARGIPLRRLGEPDDVAHAAVYL ASDESRFMTAAELVLDGGMCAV
Sequences:
>Translated_262_residues MTAVSPRLAGKCAYITGAAGGLGRAIARQMVEQGARVFLTDVADRAALDAFAAELNAGHATPVAFAAEQDVRDEARWQTL LAQANDAMGALSVLVNNAGVGSLAAPAQIELDEWRRVMAVNVESIVLGCKHALPYLSASRPASIVNISSVAAFKVEPDFT AYNASKAAVASLTKSIAIDCARRELDVRCNSIHPAFIRTGIMEPLFRTLGERDATRRLARGIPLRRLGEPDDVAHAAVYL ASDESRFMTAAELVLDGGMCAV >Mature_261_residues TAVSPRLAGKCAYITGAAGGLGRAIARQMVEQGARVFLTDVADRAALDAFAAELNAGHATPVAFAAEQDVRDEARWQTLL AQANDAMGALSVLVNNAGVGSLAAPAQIELDEWRRVMAVNVESIVLGCKHALPYLSASRPASIVNISSVAAFKVEPDFTA YNASKAAVASLTKSIAIDCARRELDVRCNSIHPAFIRTGIMEPLFRTLGERDATRRLARGIPLRRLGEPDDVAHAAVYLA SDESRFMTAAELVLDGGMCAV
Specific function: Catalyzes the degradation of 2,5-dichloro-2,5- cyclohexadiene-1,4-diol (2,5-DDOL) into 2,5-dichlorohydroquinone (2,5-DCHQ). LinX appears not to be involved in gamma-HCH degradation pathway [H]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=30.5019305019305, Blast_Score=115, Evalue=3e-26, Organism=Homo sapiens, GI40254992, Length=249, Percent_Identity=28.5140562248996, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=31.6793893129771, Blast_Score=99, Evalue=6e-21, Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=26.3358778625954, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=29.4820717131474, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=34.468085106383, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=29.2307692307692, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI31542939, Length=245, Percent_Identity=27.7551020408163, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI66933014, Length=258, Percent_Identity=31.0077519379845, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=33.160621761658, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI4758504, Length=270, Percent_Identity=30.7407407407407, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=26.2745098039216, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=30.5699481865285, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI224922801, Length=179, Percent_Identity=31.2849162011173, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI83715985, Length=270, Percent_Identity=30, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=30.9278350515464, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=26.5060240963855, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI109715829, Length=244, Percent_Identity=25.4098360655738, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4503817, Length=183, Percent_Identity=27.8688524590164, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=35.7976653696498, Blast_Score=136, Evalue=1e-33, Organism=Escherichia coli, GI1790717, Length=263, Percent_Identity=29.6577946768061, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI1786812, Length=265, Percent_Identity=30.9433962264151, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI1787905, Length=252, Percent_Identity=30.952380952381, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=30.4347826086957, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=29.9212598425197, Blast_Score=95, Evalue=6e-21, Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=29.0836653386454, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI87082160, Length=252, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=29.2, Blast_Score=89, Evalue=2e-19, Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI2367365, Length=264, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=22.9885057471264, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=26.6304347826087, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17555706, Length=260, Percent_Identity=34.6153846153846, Blast_Score=120, Evalue=1e-27, Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=31.9230769230769, Blast_Score=117, Evalue=8e-27, Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=30.2325581395349, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=28.6821705426357, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=30.3370786516854, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=28.9377289377289, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=30.3703703703704, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=29.3040293040293, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562904, Length=273, Percent_Identity=28.2051282051282, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17551412, Length=273, Percent_Identity=27.4725274725275, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17562910, Length=271, Percent_Identity=28.4132841328413, Blast_Score=94, Evalue=1e-19, Organism=Caenorhabditis elegans, GI72000259, Length=277, Percent_Identity=30.3249097472924, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=27.2727272727273, Blast_Score=91, Evalue=9e-19, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=27.6, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=29.520295202952, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=30.1587301587302, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=28.1481481481481, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=27.0676691729323, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=28.1481481481481, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=27.9245283018868, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17560150, Length=272, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17562990, Length=273, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17538182, Length=263, Percent_Identity=27.7566539923954, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17565030, Length=277, Percent_Identity=26.7148014440433, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=28.4584980237154, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=27.843137254902, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=25.8883248730964, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17567345, Length=222, Percent_Identity=23.4234234234234, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=26.2886597938144, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17564282, Length=208, Percent_Identity=26.4423076923077, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17568967, Length=200, Percent_Identity=27.5, Blast_Score=64, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17558628, Length=149, Percent_Identity=30.2013422818792, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=257, Percent_Identity=26.4591439688716, Blast_Score=67, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6322227, Length=218, Percent_Identity=29.3577981651376, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=32.4324324324324, Blast_Score=110, Evalue=8e-25, Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=32.421875, Blast_Score=107, Evalue=9e-24, Organism=Drosophila melanogaster, GI21357041, Length=266, Percent_Identity=32.3308270676692, Blast_Score=104, Evalue=7e-23, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=32.03125, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24644339, Length=263, Percent_Identity=31.9391634980989, Blast_Score=101, Evalue=6e-22, Organism=Drosophila melanogaster, GI24643142, Length=251, Percent_Identity=30.6772908366534, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI17737361, Length=264, Percent_Identity=31.8181818181818, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24644337, Length=181, Percent_Identity=37.5690607734807, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=27.843137254902, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI161076933, Length=197, Percent_Identity=27.4111675126904, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24584748, Length=197, Percent_Identity=27.4111675126904, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI21355631, Length=204, Percent_Identity=24.5098039215686, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI221331218, Length=208, Percent_Identity=25.4807692307692, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24665243, Length=208, Percent_Identity=25.4807692307692, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI281364892, Length=199, Percent_Identity=27.6381909547739, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21358495, Length=200, Percent_Identity=29.5, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI221331216, Length=209, Percent_Identity=25.3588516746411, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24665247, Length=209, Percent_Identity=25.3588516746411, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI18859837, Length=196, Percent_Identity=29.0816326530612, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 27735; Mature: 27604
Theoretical pI: Translated: 6.51; Mature: 6.51
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 4.6 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTAVSPRLAGKCAYITGAAGGLGRAIARQMVEQGARVFLTDVADRAALDAFAAELNAGHA CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCC TPVAFAAEQDVRDEARWQTLLAQANDAMGALSVLVNNAGVGSLAAPAQIELDEWRRVMAV CCEEECCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHC NVESIVLGCKHALPYLSASRPASIVNISSVAAFKVEPDFTAYNASKAAVASLTKSIAIDC CHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH ARRELDVRCNSIHPAFIRTGIMEPLFRTLGERDATRRLARGIPLRRLGEPDDVAHAAVYL HHHHHCCEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHCCCCCHHHHEEEEE ASDESRFMTAAELVLDGGMCAV ECCCHHHHHHHHHHHCCCCCCC >Mature Secondary Structure TAVSPRLAGKCAYITGAAGGLGRAIARQMVEQGARVFLTDVADRAALDAFAAELNAGHA CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCC TPVAFAAEQDVRDEARWQTLLAQANDAMGALSVLVNNAGVGSLAAPAQIELDEWRRVMAV CCEEECCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHC NVESIVLGCKHALPYLSASRPASIVNISSVAAFKVEPDFTAYNASKAAVASLTKSIAIDC CHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH ARRELDVRCNSIHPAFIRTGIMEPLFRTLGERDATRRLARGIPLRRLGEPDDVAHAAVYL HHHHHCCEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHCCCCCHHHHEEEEE ASDESRFMTAAELVLDGGMCAV ECCCHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7515041; 12450824 [H]