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The map label for this gene is nqo1 [C]

Identifier: 189352332

GI number: 189352332

Start: 382740

End: 383519

Strand: Direct

Name: nqo1 [C]

Synonym: BMULJ_03551

Alternate gene names: 189352332

Gene position: 382740-383519 (Clockwise)

Preceding gene: 189352329

Following gene: 189352336

Centisome position: 15.48

GC content: 65.0

Gene sequence:

>780_bases
ATGAACGTGCTGATCGTCTATGCACATCCCGAGCCGCGTTCGCTGAACGGCGCATTGCGCGATTTTGCCGTGGCGCGTCT
GGAAGCGGCCGGGCATACGGTGCAGGTGAGCGACCTGTATGCGATGAACTGGAAGCCCGCGCTCGACGCAAACGACATGA
TGGACCGTGCGCACGACGCGCGTTTCGATCCGGCGCTCGACTCGAAGCGCGCCTACGAGACGGGCACGCAGCGCGAAGAC
ATCGCGCGCGAGCAGGAGAAGCTCAAGTGGGCCGATACGGTGATCCTGCAGTTCCCGCTGTGGTGGTTCTCGATGCCGGC
GATCATGAAAGGGTGGGTCGAACGCGTGTATGCGTACGGCTTCGCATATGGCGTCGGCGAGCATTCCGACCGGCACTGGG
GCGATCGTTACGGCGAAGGCTCGCTCGCCGGCAAGCGCGCGATGCTGATCGTCACGACCGGCGGATGGGAATCGCACTAC
AGCGCGCGCGGCATCAACGGGCCGATCGACGACGTGCTGTTTCCGATCCAGCACGGCATCCTCTATTACCCGGGCTTCGA
CGTGTTGCCGCCGTTCGTCATCTATCAGACGCACCGGATGGACGAAGCGCGTTTCGCGGAAACGCGCGCCGCGCTCGGCA
AGCGTCTGGACGAACTCGCCACGACGCCGCCGATTCCGTATCGCCGGCAAAACGCGGGCGACTACGAGATCCCGGCGCTG
ACGCTGAAGCCGGACATCGCGCCGGGGAAGGTCGGCTTTGCCGCGCATCTGGCGGCGTAG

Upstream 100 bases:

>100_bases
GCAAATTAGTCATCGCTATACCTGGAATATCGGAAATTCATTTCCAATATACCTGCGCGATCGGCATCCTGCAGTCCATT
CAACCGACGGAGGACCGAAC

Downstream 100 bases:

>100_bases
CGCGTGCATCGCGCGGCGCGCAGGCATCGCGCGATGCACGAGCGCGATACGCGCGCCGCACGACGCAAAAACGGCACGAA
CGACCCGCGCGTTTTCGCAG

Product: NAD(P)H dehydrogenase

Products: NAD(P); reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MNVLIVYAHPEPRSLNGALRDFAVARLEAAGHTVQVSDLYAMNWKPALDANDMMDRAHDARFDPALDSKRAYETGTQRED
IAREQEKLKWADTVILQFPLWWFSMPAIMKGWVERVYAYGFAYGVGEHSDRHWGDRYGEGSLAGKRAMLIVTTGGWESHY
SARGINGPIDDVLFPIQHGILYYPGFDVLPPFVIYQTHRMDEARFAETRAALGKRLDELATTPPIPYRRQNAGDYEIPAL
TLKPDIAPGKVGFAAHLAA

Sequences:

>Translated_259_residues
MNVLIVYAHPEPRSLNGALRDFAVARLEAAGHTVQVSDLYAMNWKPALDANDMMDRAHDARFDPALDSKRAYETGTQRED
IAREQEKLKWADTVILQFPLWWFSMPAIMKGWVERVYAYGFAYGVGEHSDRHWGDRYGEGSLAGKRAMLIVTTGGWESHY
SARGINGPIDDVLFPIQHGILYYPGFDVLPPFVIYQTHRMDEARFAETRAALGKRLDELATTPPIPYRRQNAGDYEIPAL
TLKPDIAPGKVGFAAHLAA
>Mature_259_residues
MNVLIVYAHPEPRSLNGALRDFAVARLEAAGHTVQVSDLYAMNWKPALDANDMMDRAHDARFDPALDSKRAYETGTQRED
IAREQEKLKWADTVILQFPLWWFSMPAIMKGWVERVYAYGFAYGVGEHSDRHWGDRYGEGSLAGKRAMLIVTTGGWESHY
SARGINGPIDDVLFPIQHGILYYPGFDVLPPFVIYQTHRMDEARFAETRAALGKRLDELATTPPIPYRRQNAGDYEIPAL
TLKPDIAPGKVGFAAHLAA

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=226, Percent_Identity=42.0353982300885, Blast_Score=170, Evalue=1e-42,
Organism=Homo sapiens, GI4505415, Length=238, Percent_Identity=39.9159663865546, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI70995396, Length=238, Percent_Identity=32.7731092436975, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI70995422, Length=226, Percent_Identity=32.7433628318584, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1786231, Length=217, Percent_Identity=29.4930875576037, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787129, Length=127, Percent_Identity=32.2834645669291, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789750, Length=137, Percent_Identity=33.5766423357664, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 29134; Mature: 29134

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLIVYAHPEPRSLNGALRDFAVARLEAAGHTVQVSDLYAMNWKPALDANDMMDRAHDA
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHCC
RFDPALDSKRAYETGTQREDIAREQEKLKWADTVILQFPLWWFSMPAIMKGWVERVYAYG
CCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHH
FAYGVGEHSDRHWGDRYGEGSLAGKRAMLIVTTGGWESHYSARGINGPIDDVLFPIQHGI
HHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCE
LYYPGFDVLPPFVIYQTHRMDEARFAETRAALGKRLDELATTPPIPYRRQNAGDYEIPAL
EEECCCHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
TLKPDIAPGKVGFAAHLAA
EECCCCCCCCCCHHEECCC
>Mature Secondary Structure
MNVLIVYAHPEPRSLNGALRDFAVARLEAAGHTVQVSDLYAMNWKPALDANDMMDRAHDA
CCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHCC
RFDPALDSKRAYETGTQREDIAREQEKLKWADTVILQFPLWWFSMPAIMKGWVERVYAYG
CCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHH
FAYGVGEHSDRHWGDRYGEGSLAGKRAMLIVTTGGWESHYSARGINGPIDDVLFPIQHGI
HHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCE
LYYPGFDVLPPFVIYQTHRMDEARFAETRAALGKRLDELATTPPIPYRRQNAGDYEIPAL
EEECCCHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEE
TLKPDIAPGKVGFAAHLAA
EECCCCCCCCCCHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NAD(P)H2; acceptor [C]

Specific reaction: NAD(P)H2 + acceptor = NAD(P) + reduced acceptor [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]