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The map label for this gene is pnuC [H]

Identifier: 189352262

GI number: 189352262

Start: 308045

End: 308656

Strand: Direct

Name: pnuC [H]

Synonym: BMULJ_03481

Alternate gene names: 189352262

Gene position: 308045-308656 (Clockwise)

Preceding gene: 189352261

Following gene: 189352263

Centisome position: 12.46

GC content: 69.61

Gene sequence:

>612_bases
ATGTCCTCCCTCGAAATCGCCGGCGTGATCGTCAGCGCGCTCGCGATCTGGCTGACCGCGAAGCGGCGGATGCTGTGCTG
GCCGGTCGGGCTCGCGTCGGTCGCGCTGTACGGCTGGATCTTCTTCGACGCGAAGCTGTATTCCGACATGCTGCTGCAAG
GCGCGTTCGCGGTGCTGCAGGTTTACGGCTGGCGCCGCTGGCTCGCACAGCGTACGCTCGAGGCGAGCGGCCACGCGGCG
CCGGCCGGCGACGTCGCGCCCGTCACCGGCGTGCGGCCGCGGCAAATGCTGCCCGACCTGATCGCGGCCGTGATCGGCAG
CGCGCTGCTCGGCGGCATGATGGCGCGCTGGACCGACGCGGCGCTGCCGTTCGTCGATGCGTCGCTCACTGCGTTCAGCC
TCGTCGCGCAATACTGGACCGCGCGGCGCTATATCGCGTCGTGGGGCCTGTGGATCGTCGTGAATGTCGTCTACGTCGGG
ATGTTCGTGTTCAAGGCGCTGTATCTGACGGCCGGGCTCTATGCGCTGTTCATCGCGCTCGCCGTCATCGGCTGGCGCGA
CTGGAGCCGCACCGCCGATGCGCTGCGTGCCGACGCGCGCGCGGCGCACTGA

Upstream 100 bases:

>100_bases
GGGCGACGCGTATCTGTTCCCCGGCGCGCCGCGCACCGCGCGCGTGTCGTTGACCTATGATTTTTGATCGCCGCGCAGCG
GCTACCCAGGAGCCCATACG

Downstream 100 bases:

>100_bases
TCCACGCGATTCAATTACGGAGCGACGTCGTTCATGTCTTTTCCCCTCGAGCCGGACGGTCCTGCCGCACGCGAGGTCGC
ACCGCCGCAGTTCGGCGTCG

Product: nicotinamide mononucleotide transporter

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MSSLEIAGVIVSALAIWLTAKRRMLCWPVGLASVALYGWIFFDAKLYSDMLLQGAFAVLQVYGWRRWLAQRTLEASGHAA
PAGDVAPVTGVRPRQMLPDLIAAVIGSALLGGMMARWTDAALPFVDASLTAFSLVAQYWTARRYIASWGLWIVVNVVYVG
MFVFKALYLTAGLYALFIALAVIGWRDWSRTADALRADARAAH

Sequences:

>Translated_203_residues
MSSLEIAGVIVSALAIWLTAKRRMLCWPVGLASVALYGWIFFDAKLYSDMLLQGAFAVLQVYGWRRWLAQRTLEASGHAA
PAGDVAPVTGVRPRQMLPDLIAAVIGSALLGGMMARWTDAALPFVDASLTAFSLVAQYWTARRYIASWGLWIVVNVVYVG
MFVFKALYLTAGLYALFIALAVIGWRDWSRTADALRADARAAH
>Mature_202_residues
SSLEIAGVIVSALAIWLTAKRRMLCWPVGLASVALYGWIFFDAKLYSDMLLQGAFAVLQVYGWRRWLAQRTLEASGHAAP
AGDVAPVTGVRPRQMLPDLIAAVIGSALLGGMMARWTDAALPFVDASLTAFSLVAQYWTARRYIASWGLWIVVNVVYVGM
FVFKALYLTAGLYALFIALAVIGWRDWSRTADALRADARAAH

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=208, Percent_Identity=28.3653846153846, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 22257; Mature: 22126

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLEIAGVIVSALAIWLTAKRRMLCWPVGLASVALYGWIFFDAKLYSDMLLQGAFAVLQ
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYGWRRWLAQRTLEASGHAAPAGDVAPVTGVRPRQMLPDLIAAVIGSALLGGMMARWTDA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPFVDASLTAFSLVAQYWTARRYIASWGLWIVVNVVYVGMFVFKALYLTAGLYALFIAL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVIGWRDWSRTADALRADARAAH
HHHHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSLEIAGVIVSALAIWLTAKRRMLCWPVGLASVALYGWIFFDAKLYSDMLLQGAFAVLQ
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYGWRRWLAQRTLEASGHAAPAGDVAPVTGVRPRQMLPDLIAAVIGSALLGGMMARWTDA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALPFVDASLTAFSLVAQYWTARRYIASWGLWIVVNVVYVGMFVFKALYLTAGLYALFIAL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVIGWRDWSRTADALRADARAAH
HHHHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2198247; 11677609 [H]