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The map label for this gene is rhtC [H]

Identifier: 189352244

GI number: 189352244

Start: 285580

End: 286218

Strand: Direct

Name: rhtC [H]

Synonym: BMULJ_03462

Alternate gene names: 189352244

Gene position: 285580-286218 (Clockwise)

Preceding gene: 189352241

Following gene: 189352245

Centisome position: 11.55

GC content: 67.92

Gene sequence:

>639_bases
ATGACTGCAACGGCCGCCGTATTCGCGATTCTCGCCGCGCTGTGGCTCGGCGCCATGATTCCCGGCCCCAGTTTCGTGCT
GGTGGCGCGCAATTCGATCGGGCTGTCGCGCCGCGACGGTCTCGCGACGGCGCTCGGCATGGGCGTCGGCGGCATCGCGT
TCGGCGGCGTCGCGCTCGCCGGGCTCTATACGCTGCTGCAGACGGTCGAATGGCTCTATGTCGGGCTCAAGATCGCGGGC
GGCGCGTATCTGATCTACATGGCGTCGAAAATCTGGCGCGGCGCGGATCGCCCGATCGCGATGGACGACTCGCGGGCAGC
TCCCGCCGGCAGCGCGCGCAAGTCGTTCCTGACCGGCCTGACGACGCAGCTCAGCAACCCGAAGACGGCGATCTGGTACG
GCAGCATCTTCGCGGCGCTGCTGCCGCAGCATCCGCCGCTGTGGTGCTATCTCGCGCTGCCGCCGCTCGTGTTCGGCGTC
GAATTCGGCTGGTACACGATCGTCGCGCTGTGCTTTTCGACGCGGCGGCCGCGCGAACTCTATCTGCGCGCGAAGAAATG
GGTCGACCGCGTCGCGGCCGGCGCGATCGCGTTGCTCGGGTTGCGGTTGATTCTGAACGCGCCGAAGGTGGGGATCTGA

Upstream 100 bases:

>100_bases
CGTCGCGCTTTCGGCCGCGCGCAAGGCGTGCCAGAATCGGCGGCTGGAACGCAGGAGCGCGCGGCGTCGTCGCGGCGGCG
TTTCGTTCGAGGAGACTTCG

Downstream 100 bases:

>100_bases
GCGGTTTGGGTGTGGCGGTGTTGTTCGGCCGGCGGGCGATGTGGTTGGCGGCGTCGGTTGCTGTGCCGGGCGATGCACAG
TGCTGCTTTTGCGCGTCGCT

Product: putative threonine efflux protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTATAAVFAILAALWLGAMIPGPSFVLVARNSIGLSRRDGLATALGMGVGGIAFGGVALAGLYTLLQTVEWLYVGLKIAG
GAYLIYMASKIWRGADRPIAMDDSRAAPAGSARKSFLTGLTTQLSNPKTAIWYGSIFAALLPQHPPLWCYLALPPLVFGV
EFGWYTIVALCFSTRRPRELYLRAKKWVDRVAAGAIALLGLRLILNAPKVGI

Sequences:

>Translated_212_residues
MTATAAVFAILAALWLGAMIPGPSFVLVARNSIGLSRRDGLATALGMGVGGIAFGGVALAGLYTLLQTVEWLYVGLKIAG
GAYLIYMASKIWRGADRPIAMDDSRAAPAGSARKSFLTGLTTQLSNPKTAIWYGSIFAALLPQHPPLWCYLALPPLVFGV
EFGWYTIVALCFSTRRPRELYLRAKKWVDRVAAGAIALLGLRLILNAPKVGI
>Mature_211_residues
TATAAVFAILAALWLGAMIPGPSFVLVARNSIGLSRRDGLATALGMGVGGIAFGGVALAGLYTLLQTVEWLYVGLKIAGG
AYLIYMASKIWRGADRPIAMDDSRAAPAGSARKSFLTGLTTQLSNPKTAIWYGSIFAALLPQHPPLWCYLALPPLVFGVE
FGWYTIVALCFSTRRPRELYLRAKKWVDRVAAGAIALLGLRLILNAPKVGI

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=193, Percent_Identity=31.0880829015544, Blast_Score=106, Evalue=9e-25,
Organism=Escherichia coli, GI1786522, Length=184, Percent_Identity=30.9782608695652, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22608; Mature: 22477

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATAAVFAILAALWLGAMIPGPSFVLVARNSIGLSRRDGLATALGMGVGGIAFGGVALA
CCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHH
GLYTLLQTVEWLYVGLKIAGGAYLIYMASKIWRGADRPIAMDDSRAAPAGSARKSFLTGL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHHHH
TTQLSNPKTAIWYGSIFAALLPQHPPLWCYLALPPLVFGVEFGWYTIVALCFSTRRPREL
HHHCCCCCEEEHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHH
YLRAKKWVDRVAAGAIALLGLRLILNAPKVGI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TATAAVFAILAALWLGAMIPGPSFVLVARNSIGLSRRDGLATALGMGVGGIAFGGVALA
CHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHH
GLYTLLQTVEWLYVGLKIAGGAYLIYMASKIWRGADRPIAMDDSRAAPAGSARKSFLTGL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHHHH
TTQLSNPKTAIWYGSIFAALLPQHPPLWCYLALPPLVFGVEFGWYTIVALCFSTRRPREL
HHHCCCCCEEEHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHH
YLRAKKWVDRVAAGAIALLGLRLILNAPKVGI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]