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The map label for this gene is kipR [H]

Identifier: 189352241

GI number: 189352241

Start: 282269

End: 283147

Strand: Direct

Name: kipR [H]

Synonym: BMULJ_03459

Alternate gene names: 189352241

Gene position: 282269-283147 (Clockwise)

Preceding gene: 189352232

Following gene: 189352244

Centisome position: 11.41

GC content: 72.24

Gene sequence:

>879_bases
ATGCAGGAACCGCATTCGCCCGGAACGTCGCGCGCCGCGCCCGCCGACGGCGACGCCGCCGACACGGGCGGCGCGCCGGG
CACCGGCATGCTGCAGCGGGCGTTCGCGATCCTGCGCGCGCTGGCCGGCATGCAGCAGGACGGCGTGCGCGTCACGCATC
TCGCGAAGGCGGTCGGCCTCACGCAGGGCACCGCGCACCGGATCCTGCAGTCGCTGATCGCCGAAGGCATGGTCGAGCAG
GACGAGCGCTCGAAGCTGTACCGGCTCAGTGTCGACTTCTTCGCGCTCGCCGCGCTGGCCGGCAATCCGAGCAGCATGCG
CACGCTGTGCCGGCCCGCGCTGCTGCGGCTCTGCGCGAGCCTCGGCGAGACGATCTTCCTGCTCGTGAAGAGCGGCTTCG
ACGCGGTGTGCCTCGATCTCTGCGAGGGGCCGTTTCCGATCCGGTCGTTTACCGGCGACATCGGCGGGCGCGTCGCGCTC
GGCGTCGGGCAGGGCAGCCTCGCGATCCTCGCGTTCCTGCCGGAAGCCGAGCGCGAGGAGGTGATCCGCTTCAACGTGCC
GCGCATACGCGGCTACGGCGTGCTCGACGAGGTCTATCTGCGCACCGAGATCGACCGCGTGCGGCAGCTCGGCTACGCGG
GCCGCAATAGCGGCGTGCTCGACGGGATGGCCGGCGTCGCGGTGCCGATCCTCGATCGCACCGGCTATCCGGTCGGCGCG
CTGAGCGTCGGTACGCTCGCGTCGCGCCTCGGCGACGACCGGATGCCGATGGTCGTCGAACTGCTGCGCCGCCAGGCCGA
GGCGATCGGCCCGCGCACGAATCCGTTCGACGCCGCGCTGCGGCGGCCGATGCACGGGCTGTCCGGGAAAGCCGGATAG

Upstream 100 bases:

>100_bases
GCCCGTCAATCCCGTGCACACCCGGATGCCGGGCGCGTCCGCATGCGGCGACAATGGCGGCTCCGTATTCCGTTCAATGA
AATCGTCGAGGAGAGCCGGC

Downstream 100 bases:

>100_bases
GCGCGGCAGCGTCGGGCGGCACCGTGCGGCGCTGGTGCATCGGTAGCTACAGCGGGCCGTCCCGTGCGTTCAACGCGTCG
AGTAACGCGTTCAGCCTCGC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MQEPHSPGTSRAAPADGDAADTGGAPGTGMLQRAFAILRALAGMQQDGVRVTHLAKAVGLTQGTAHRILQSLIAEGMVEQ
DERSKLYRLSVDFFALAALAGNPSSMRTLCRPALLRLCASLGETIFLLVKSGFDAVCLDLCEGPFPIRSFTGDIGGRVAL
GVGQGSLAILAFLPEAEREEVIRFNVPRIRGYGVLDEVYLRTEIDRVRQLGYAGRNSGVLDGMAGVAVPILDRTGYPVGA
LSVGTLASRLGDDRMPMVVELLRRQAEAIGPRTNPFDAALRRPMHGLSGKAG

Sequences:

>Translated_292_residues
MQEPHSPGTSRAAPADGDAADTGGAPGTGMLQRAFAILRALAGMQQDGVRVTHLAKAVGLTQGTAHRILQSLIAEGMVEQ
DERSKLYRLSVDFFALAALAGNPSSMRTLCRPALLRLCASLGETIFLLVKSGFDAVCLDLCEGPFPIRSFTGDIGGRVAL
GVGQGSLAILAFLPEAEREEVIRFNVPRIRGYGVLDEVYLRTEIDRVRQLGYAGRNSGVLDGMAGVAVPILDRTGYPVGA
LSVGTLASRLGDDRMPMVVELLRRQAEAIGPRTNPFDAALRRPMHGLSGKAG
>Mature_292_residues
MQEPHSPGTSRAAPADGDAADTGGAPGTGMLQRAFAILRALAGMQQDGVRVTHLAKAVGLTQGTAHRILQSLIAEGMVEQ
DERSKLYRLSVDFFALAALAGNPSSMRTLCRPALLRLCASLGETIFLLVKSGFDAVCLDLCEGPFPIRSFTGDIGGRVAL
GVGQGSLAILAFLPEAEREEVIRFNVPRIRGYGVLDEVYLRTEIDRVRQLGYAGRNSGVLDGMAGVAVPILDRTGYPVGA
LSVGTLASRLGDDRMPMVVELLRRQAEAIGPRTNPFDAALRRPMHGLSGKAG

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=240, Percent_Identity=24.1666666666667, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87082359, Length=238, Percent_Identity=25.2100840336134, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788131, Length=263, Percent_Identity=24.7148288973384, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786715, Length=256, Percent_Identity=25.78125, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30950; Mature: 30950

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEPHSPGTSRAAPADGDAADTGGAPGTGMLQRAFAILRALAGMQQDGVRVTHLAKAVGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
TQGTAHRILQSLIAEGMVEQDERSKLYRLSVDFFALAALAGNPSSMRTLCRPALLRLCAS
CCHHHHHHHHHHHHHHHHCCHHHHHHEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LGETIFLLVKSGFDAVCLDLCEGPFPIRSFTGDIGGRVALGVGQGSLAILAFLPEAEREE
HHHHEEHHHHCCCHHHHHHHHCCCCCHHHHCCCCCCEEEEEECCCCEEEEEECCCCCHHH
VIRFNVPRIRGYGVLDEVYLRTEIDRVRQLGYAGRNSGVLDGMAGVAVPILDRTGYPVGA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCH
LSVGTLASRLGDDRMPMVVELLRRQAEAIGPRTNPFDAALRRPMHGLSGKAG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHCCCCCCC
>Mature Secondary Structure
MQEPHSPGTSRAAPADGDAADTGGAPGTGMLQRAFAILRALAGMQQDGVRVTHLAKAVGL
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
TQGTAHRILQSLIAEGMVEQDERSKLYRLSVDFFALAALAGNPSSMRTLCRPALLRLCAS
CCHHHHHHHHHHHHHHHHCCHHHHHHEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LGETIFLLVKSGFDAVCLDLCEGPFPIRSFTGDIGGRVALGVGQGSLAILAFLPEAEREE
HHHHEEHHHHCCCHHHHHHHHCCCCCHHHHCCCCCCEEEEEECCCCEEEEEECCCCCHHH
VIRFNVPRIRGYGVLDEVYLRTEIDRVRQLGYAGRNSGVLDGMAGVAVPILDRTGYPVGA
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCH
LSVGTLASRLGDDRMPMVVELLRRQAEAIGPRTNPFDAALRRPMHGLSGKAG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]