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The map label for this gene is ttuB [H]

Identifier: 189352204

GI number: 189352204

Start: 242866

End: 244176

Strand: Direct

Name: ttuB [H]

Synonym: BMULJ_03422

Alternate gene names: 189352204

Gene position: 242866-244176 (Clockwise)

Preceding gene: 189352203

Following gene: 189352205

Centisome position: 9.82

GC content: 67.66

Gene sequence:

>1311_bases
GTGAATTCCACCGCCTACCCGGACGCCGCGTCCGCCGACGAACAGCGCATCATGTCGAAGATGGCGCGGCGCCTGCTGCC
CATACTCGTCGTGATGTTCCTGATCGCCTTCATCGACCGGCAGAACGTCGGTTTCGCGAAACTGCAGATGGTGCACAGCC
TCGGGCTGACGGAGGCCGCGTTCGGGCTCGCGTCGTCGCTGTTCTTCATCGGCTATCTGCTGTTCGAAGTGCCGAGCACG
CTCGCGCTGCATCGCTACGGCGCGCGCGTCTGGCTCGCACGCATCATGCTGACGTGGGGGCTCATCACGGTGCTGATGGG
CTTCACGACCTCGATGCCCGTGTTCTGCGCGCTGCGCTTTCTGCTCGGCATCGCCGAGGCCGGGTTCTATCCGGGCGTCA
TCTACTACCTGACGCTGTGGTTTCCGCAGAGCTATCGCGCGAAGGTGCTCGGCATCTTCACGCTCGGCAGCGCGCTCGCG
AACATGCTCGGGTCGCTGGTCGGCGGCGTGCTGCTGAGCCTGAACGGCGTCTGGGGCCTCGCCGGCTGGCAATGGGTGTT
CGTCGCGACCGGCATTCCGGCCGTGCTCGTCGCGATCGTCGTGTTCCGCGTGCTGCCGGCGTCGTTCCGCGAGGCGCGTT
TCCTCGACGAGCGCGAAAAGCAGATCGTCGCGGCCGCGCTCGAGCGCGAAAAGCCCGCGCAGGCCGAGCATGCGCAGCCG
TGGAAGGCGCTGCTCGATCCGCGCGTGATGCTGTTCGCGGCGACCTACATGCTGATGTCGACGTCGCTCTACGGCGTCAC
GTACTGGCTGCCGACGCTCGTGAAGTCGTTCGGCGTGTCGAGCAGCACGAACGGCTTGCTGAGCATGCTGCCGTGGGCGC
TCGCGGTGCTGCTGCTGTTGTGGCTGCCGGCGAAGCTGCGCCGCGCGAAGAGCATTCTGCGCACGATCTCGATCGTCGCG
GCGCTCGGCGCGCTCGGCTTCCTGCTGAGTCTCGTGCTGCCGTCGACGCCGCTGCGCTTCGTCGCGCTCGTGCTCGGCGG
CGCCTGCATTCCGCTGCTGTATCCGTGCTTCTGGTCGATGCCGCCGCGCTACTTCACCGGCGCGCGTGCGGCGGCGAGCG
TCGCGGCGATCAATTCGATCGGCAACCTCGGCGGTTTCTTCAGCCAGAACCTGATGCCGTTCGCCGGCAAGGTGACGGGC
ACCGCATTCGGGCCGATGATCGTGCCGATCGTGTGCCTCGCCGTGCTCGGCATCGGCGCGCTCGTCGCGTGGACGCGTAG
CGAGCGCGCGATGGTCGCGGCCGGCGCCTGA

Upstream 100 bases:

>100_bases
GAGCGCAGCCGGCCATTCCCGTCATGCCGCGATCGCGCGCCTGTCGCGCGCGGCGCACCGCATTTCAACGATACGCAACC
GTTTCACGGAGGTACCTGCA

Downstream 100 bases:

>100_bases
GTGCATCGCGGCACCGTCGGGCGCGATGCCTGAGCCGGGGGTGCGCCCGCGCGCGCGGTGCGCGCAACGATCGACGCGCG
TGACGGCGATGCGCTGACGA

Product: permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MNSTAYPDAASADEQRIMSKMARRLLPILVVMFLIAFIDRQNVGFAKLQMVHSLGLTEAAFGLASSLFFIGYLLFEVPST
LALHRYGARVWLARIMLTWGLITVLMGFTTSMPVFCALRFLLGIAEAGFYPGVIYYLTLWFPQSYRAKVLGIFTLGSALA
NMLGSLVGGVLLSLNGVWGLAGWQWVFVATGIPAVLVAIVVFRVLPASFREARFLDEREKQIVAAALEREKPAQAEHAQP
WKALLDPRVMLFAATYMLMSTSLYGVTYWLPTLVKSFGVSSSTNGLLSMLPWALAVLLLLWLPAKLRRAKSILRTISIVA
ALGALGFLLSLVLPSTPLRFVALVLGGACIPLLYPCFWSMPPRYFTGARAAASVAAINSIGNLGGFFSQNLMPFAGKVTG
TAFGPMIVPIVCLAVLGIGALVAWTRSERAMVAAGA

Sequences:

>Translated_436_residues
MNSTAYPDAASADEQRIMSKMARRLLPILVVMFLIAFIDRQNVGFAKLQMVHSLGLTEAAFGLASSLFFIGYLLFEVPST
LALHRYGARVWLARIMLTWGLITVLMGFTTSMPVFCALRFLLGIAEAGFYPGVIYYLTLWFPQSYRAKVLGIFTLGSALA
NMLGSLVGGVLLSLNGVWGLAGWQWVFVATGIPAVLVAIVVFRVLPASFREARFLDEREKQIVAAALEREKPAQAEHAQP
WKALLDPRVMLFAATYMLMSTSLYGVTYWLPTLVKSFGVSSSTNGLLSMLPWALAVLLLLWLPAKLRRAKSILRTISIVA
ALGALGFLLSLVLPSTPLRFVALVLGGACIPLLYPCFWSMPPRYFTGARAAASVAAINSIGNLGGFFSQNLMPFAGKVTG
TAFGPMIVPIVCLAVLGIGALVAWTRSERAMVAAGA
>Mature_436_residues
MNSTAYPDAASADEQRIMSKMARRLLPILVVMFLIAFIDRQNVGFAKLQMVHSLGLTEAAFGLASSLFFIGYLLFEVPST
LALHRYGARVWLARIMLTWGLITVLMGFTTSMPVFCALRFLLGIAEAGFYPGVIYYLTLWFPQSYRAKVLGIFTLGSALA
NMLGSLVGGVLLSLNGVWGLAGWQWVFVATGIPAVLVAIVVFRVLPASFREARFLDEREKQIVAAALEREKPAQAEHAQP
WKALLDPRVMLFAATYMLMSTSLYGVTYWLPTLVKSFGVSSSTNGLLSMLPWALAVLLLLWLPAKLRRAKSILRTISIVA
ALGALGFLLSLVLPSTPLRFVALVLGGACIPLLYPCFWSMPPRYFTGARAAASVAAINSIGNLGGFFSQNLMPFAGKVTG
TAFGPMIVPIVCLAVLGIGALVAWTRSERAMVAAGA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=389, Percent_Identity=33.6760925449871, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI87082320, Length=307, Percent_Identity=26.0586319218241, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789515, Length=297, Percent_Identity=24.5791245791246, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789152, Length=360, Percent_Identity=24.4444444444444, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI2367379, Length=440, Percent_Identity=23.6363636363636, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322025, Length=246, Percent_Identity=26.0162601626016, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6319876, Length=274, Percent_Identity=26.2773722627737, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6321698, Length=287, Percent_Identity=20.2090592334495, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322612, Length=290, Percent_Identity=24.8275862068966, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6319250, Length=235, Percent_Identity=23.4042553191489, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321502, Length=352, Percent_Identity=25.8522727272727, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20130135, Length=350, Percent_Identity=22.2857142857143, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47199; Mature: 47199

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCEEECCC
>Mature Secondary Structure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HHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]