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The map label for this gene is yhcS [C]

Identifier: 189352163

GI number: 189352163

Start: 191835

End: 192806

Strand: Direct

Name: yhcS [C]

Synonym: BMULJ_03381

Alternate gene names: 189352163

Gene position: 191835-192806 (Clockwise)

Preceding gene: 189352161

Following gene: 189352164

Centisome position: 7.76

GC content: 72.74

Gene sequence:

>972_bases
ATGGACGAGCGGTTGAGGGGTGTCGCCGAATTCGTCGAGGTCGTGGAATCGGGCAGCTTCGCCGCGGCGGCGTTGCGCAT
CGGCGTCACGCGCTCGGCGGTGGCGAAGGTCGTCGCGCGGCTCGAACGCCGGCTCGGCGTGCGACTGTTGCAGCGCACGA
CGCGGCAGCTCAACCTGACCGACGAAGGACATCTGTACTACGAGCAATGCCGGCGGCTGCTGGCCGAACTCGGCGACACG
GAAGCCGCGCTCGACGCGGGCCGTCGCGAGCCGTCCGGGCGGCTGCGCATCAGCGTGCCGGTGCTGTTCGGCAGGCAATG
CGTGGCGCCCGTGATGCGGCGGCTCGTCGAGCGTCATCCGCGGCTCGAGGTCGACATGTCGTTCAGCGATCGCGTCGCCG
ACCTGATCGACGACGGTTTCGACATCGCAGTGCGCATCGGCGTGCTCGCCGATACGACGGCGCTGGTCGCGCGGCGGCTC
GGCGTGCAGCGGATGGGCATCTGCGCGTCGCCGGCGTATCTCGACCGGCACGGCTGGCCGTCGGGGCCGGACGCACTCGC
GTCGCACGTCGGCATTCCCTATGCACGCGGCGGCCAGCCCGTGCCGTGGCGGATCATCGGCGCGGACGGCGAGGTGCGCG
AGCATCGCGTGACCGGGCGCCTGCGCTACGACGACCTGCAGGCGATCGCGGAGGCCGCGGCGGCCGGAGCGGGCCTCGCA
TGGCTGCCGTGCTGGCTGATGGCGCCGTACCTGCGCGACGGCCGTCTCGCGCTCGTGATGGACAGCAACAGCGTGTCGGG
TGCCGACGTGTCGGCGGTGCGGCCGCAGGCGCGGCACGTGCCGTCGAAGGTGCGCGTGGCGATCGATGCGCTCGTCGACG
AGATTCCGCGCATGCTCGCGTCGGACGACGCTGCGCCGCCGGCGCCGACACCGGCGCGTTCGCGCGCGCGACGCGCGCGT
TCCGCTGGCTGA

Upstream 100 bases:

>100_bases
CTATCATAGTGTTGCTTGACGGGACGCATTGACGAGAATCGGGACACTGACTGTCGCCAATGTGGAAACAAATGCGCGCA
TCACAACGGAGTGACATTGC

Downstream 100 bases:

>100_bases
CGGGCGGTTGCGCCGGCGCGTATGATGGCCGCATCGTGAGCGTTTCGGACAACCCATGAGCGTGATCGGCGCGTCGGATC
GCGGTGGCAAGCCCGGCTGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MDERLRGVAEFVEVVESGSFAAAALRIGVTRSAVAKVVARLERRLGVRLLQRTTRQLNLTDEGHLYYEQCRRLLAELGDT
EAALDAGRREPSGRLRISVPVLFGRQCVAPVMRRLVERHPRLEVDMSFSDRVADLIDDGFDIAVRIGVLADTTALVARRL
GVQRMGICASPAYLDRHGWPSGPDALASHVGIPYARGGQPVPWRIIGADGEVREHRVTGRLRYDDLQAIAEAAAAGAGLA
WLPCWLMAPYLRDGRLALVMDSNSVSGADVSAVRPQARHVPSKVRVAIDALVDEIPRMLASDDAAPPAPTPARSRARRAR
SAG

Sequences:

>Translated_323_residues
MDERLRGVAEFVEVVESGSFAAAALRIGVTRSAVAKVVARLERRLGVRLLQRTTRQLNLTDEGHLYYEQCRRLLAELGDT
EAALDAGRREPSGRLRISVPVLFGRQCVAPVMRRLVERHPRLEVDMSFSDRVADLIDDGFDIAVRIGVLADTTALVARRL
GVQRMGICASPAYLDRHGWPSGPDALASHVGIPYARGGQPVPWRIIGADGEVREHRVTGRLRYDDLQAIAEAAAAGAGLA
WLPCWLMAPYLRDGRLALVMDSNSVSGADVSAVRPQARHVPSKVRVAIDALVDEIPRMLASDDAAPPAPTPARSRARRAR
SAG
>Mature_323_residues
MDERLRGVAEFVEVVESGSFAAAALRIGVTRSAVAKVVARLERRLGVRLLQRTTRQLNLTDEGHLYYEQCRRLLAELGDT
EAALDAGRREPSGRLRISVPVLFGRQCVAPVMRRLVERHPRLEVDMSFSDRVADLIDDGFDIAVRIGVLADTTALVARRL
GVQRMGICASPAYLDRHGWPSGPDALASHVGIPYARGGQPVPWRIIGADGEVREHRVTGRLRYDDLQAIAEAAAAGAGLA
WLPCWLMAPYLRDGRLALVMDSNSVSGADVSAVRPQARHVPSKVRVAIDALVDEIPRMLASDDAAPPAPTPARSRARRAR
SAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=291, Percent_Identity=32.6460481099656, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=31.6151202749141, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=33.6769759450172, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=30.1369863013699, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87081978, Length=284, Percent_Identity=32.3943661971831, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787128, Length=290, Percent_Identity=26.551724137931, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1789440, Length=283, Percent_Identity=29.3286219081272, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786448, Length=282, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI157672245, Length=142, Percent_Identity=29.5774647887324, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789173, Length=172, Percent_Identity=28.4883720930233, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788481, Length=149, Percent_Identity=28.8590604026846, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35138; Mature: 35138

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDERLRGVAEFVEVVESGSFAAAALRIGVTRSAVAKVVARLERRLGVRLLQRTTRQLNLT
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DEGHLYYEQCRRLLAELGDTEAALDAGRREPSGRLRISVPVLFGRQCVAPVMRRLVERHP
CCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCC
RLEVDMSFSDRVADLIDDGFDIAVRIGVLADTTALVARRLGVQRMGICASPAYLDRHGWP
CEEEECCHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHCHHHHCCCCCCCHHHCCCCC
SGPDALASHVGIPYARGGQPVPWRIIGADGEVREHRVTGRLRYDDLQAIAEAAAAGAGLA
CCHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCHH
WLPCWLMAPYLRDGRLALVMDSNSVSGADVSAVRPQARHVPSKVRVAIDALVDEIPRMLA
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHCCCHHHCCCHHHHHHHHHHHHHHHHHHH
SDDAAPPAPTPARSRARRARSAG
CCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MDERLRGVAEFVEVVESGSFAAAALRIGVTRSAVAKVVARLERRLGVRLLQRTTRQLNLT
CCHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DEGHLYYEQCRRLLAELGDTEAALDAGRREPSGRLRISVPVLFGRQCVAPVMRRLVERHP
CCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCC
RLEVDMSFSDRVADLIDDGFDIAVRIGVLADTTALVARRLGVQRMGICASPAYLDRHGWP
CEEEECCHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHCHHHHCCCCCCCHHHCCCCC
SGPDALASHVGIPYARGGQPVPWRIIGADGEVREHRVTGRLRYDDLQAIAEAAAAGAGLA
CCHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCHH
WLPCWLMAPYLRDGRLALVMDSNSVSGADVSAVRPQARHVPSKVRVAIDALVDEIPRMLA
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHCCCHHHCCCHHHHHHHHHHHHHHHHHHH
SDDAAPPAPTPARSRARRARSAG
CCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]