BacMap

Definition	Burkholderia multivorans ATCC 17616 chromosome 2, complete genome.
Accession	NC_010805
Length	2,473,162

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The map label for this gene is fabG [H]

Identifier: 189352154

GI number: 189352154

Start: 182810

End: 183514

Strand: Direct

Name: fabG [H]

Synonym: BMULJ_03372

Alternate gene names: 189352154

Gene position: 182810-183514 (Clockwise)

Preceding gene: 189352152

Following gene: 189352155

Centisome position: 7.39

GC content: 68.51

Gene sequence:

>705_bases
GTGACTGTAGAAAAAGTGGCGCTGATCACGGCGGCGGGCAAGGGCATGGGCGCGGCGATCGCGCGCGAACTGGCGGCGGG
CGGCTATCGCGTCGCGCTGATGTCGCCGTCCGGCAGCGCGGTCGCGCTCGGCGACGAACTCGGCGGCTTCGGGATTCGCG
GGTCGGTCACCGAGGAAGCCGATATCGACCGGCTCGTGCAGGACACGCTCGCGCGCTACGGCCGGATCGACGCGGTCGTG
AACAACACGGGCCATCCGCCGAAGGGCGATCTGCTGTCGATCACCGACGACAACTGGCATGCGGGGCTCGACCTGATCCT
GCTGAACGTCGTGCGCGTCATGCGCCGCGTGACGCCGGTGTTCCAGCAGCAGGGCGGCGGCGCGGTCGTCAATATCTCGA
GCTTCGCGGCCGATGCGCCGGAGCAGCCGATGCCGGTGTCGTCGGCATTGCGCGCGGCGCTGAGCGCGTGGACGCGTCTC
TATGCGGAGCGCTACGCGGCCGACAACATCCGCATGAATGCCGTGCTGCCCGGCTTCATCGACAGCTGGCCGGAAACGCC
GGAGATCGTCGCGCGGATTCCTGCCGGCCGTTTCGGCAAGACGGCCGAGATCGCGAAGACGGTCGCGTTCCTGTTGTCCG
ACGGTGCCGGCTACATCACCGGCCAGAACATTCGCGTCGACGGCGCGATCGTGAAGGCGCTCTGA

Upstream 100 bases:

>100_bases
GAAATACTGGTTCGACATCGCTGCGCGATGCGCCTACATTACCACCGAGGCGCGCCGGCGGGCGGCTGCGCGGCGACAGC
ATCGTGACGAGGAGCATATC

Downstream 100 bases:

>100_bases
GCGCAGCGGCCGCGCCGGCTCATGCGCGCGCCGGCGTCGCGCCGATCCTCCGGAAAGCGTCGTTTCGCGGCGATTTTTGA
ATCGCTGTGTGTCGTGCGCA

Product: 3-oxoacyl-[acyl-carrier protein] reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTVEKVALITAAGKGMGAAIARELAAGGYRVALMSPSGSAVALGDELGGFGIRGSVTEEADIDRLVQDTLARYGRIDAVV
NNTGHPPKGDLLSITDDNWHAGLDLILLNVVRVMRRVTPVFQQQGGGAVVNISSFAADAPEQPMPVSSALRAALSAWTRL
YAERYAADNIRMNAVLPGFIDSWPETPEIVARIPAGRFGKTAEIAKTVAFLLSDGAGYITGQNIRVDGAIVKAL

Sequences:

>Translated_234_residues
MTVEKVALITAAGKGMGAAIARELAAGGYRVALMSPSGSAVALGDELGGFGIRGSVTEEADIDRLVQDTLARYGRIDAVV
NNTGHPPKGDLLSITDDNWHAGLDLILLNVVRVMRRVTPVFQQQGGGAVVNISSFAADAPEQPMPVSSALRAALSAWTRL
YAERYAADNIRMNAVLPGFIDSWPETPEIVARIPAGRFGKTAEIAKTVAFLLSDGAGYITGQNIRVDGAIVKAL
>Mature_233_residues
TVEKVALITAAGKGMGAAIARELAAGGYRVALMSPSGSAVALGDELGGFGIRGSVTEEADIDRLVQDTLARYGRIDAVVN
NTGHPPKGDLLSITDDNWHAGLDLILLNVVRVMRRVTPVFQQQGGGAVVNISSFAADAPEQPMPVSSALRAALSAWTRLY
AERYAADNIRMNAVLPGFIDSWPETPEIVARIPAGRFGKTAEIAKTVAFLLSDGAGYITGQNIRVDGAIVKAL

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=31.3559322033898, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=32.6446280991736, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=31.4741035856574, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5031737, Length=244, Percent_Identity=29.5081967213115, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI59889578, Length=224, Percent_Identity=32.5892857142857, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=27.7551020408163, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=28.2868525896414, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI7705925, Length=232, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI126723191, Length=179, Percent_Identity=31.8435754189944, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI66933014, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=30.1075268817204, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=27.2251308900524, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787335, Length=236, Percent_Identity=33.4745762711864, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI87082100, Length=245, Percent_Identity=33.0612244897959, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789208, Length=240, Percent_Identity=28.3333333333333, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=31.8548387096774, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082160, Length=239, Percent_Identity=25.9414225941423, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=30.6122448979592, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=29.3388429752066, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=25.4032258064516, Blast_Score=72, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=31.2757201646091, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=31.6, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=31.0204081632653, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=30.7692307692308, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=30.188679245283, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=29.4573643410853, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI25147288, Length=237, Percent_Identity=29.1139240506329, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=246, Percent_Identity=28.0487804878049, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=260, Percent_Identity=29.2307692307692, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=257, Percent_Identity=29.9610894941634, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=272, Percent_Identity=30.8823529411765, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=238, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=25.9541984732824, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=28.4644194756554, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=193, Percent_Identity=32.6424870466321, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=28.4090909090909, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=258, Percent_Identity=29.0697674418605, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=24.7011952191235, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=196, Percent_Identity=31.1224489795918, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=27.7153558052434, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=193, Percent_Identity=32.1243523316062, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=196, Percent_Identity=30.6122448979592, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=25.9259259259259, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=29.2682926829268, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI23397609, Length=244, Percent_Identity=34.4262295081967, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=29.045643153527, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24643142, Length=235, Percent_Identity=25.9574468085106, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28571526, Length=245, Percent_Identity=27.7551020408163, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=27.5590551181102, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357041, Length=245, Percent_Identity=25.7142857142857, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24585; Mature: 24454

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVEKVALITAAGKGMGAAIARELAAGGYRVALMSPSGSAVALGDELGGFGIRGSVTEEA
CCCHHEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCHH
DIDRLVQDTLARYGRIDAVVNNTGHPPKGDLLSITDDNWHAGLDLILLNVVRVMRRVTPV
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
FQQQGGGAVVNISSFAADAPEQPMPVSSALRAALSAWTRLYAERYAADNIRMNAVLPGFI
HHHCCCCEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHH
DSWPETPEIVARIPAGRFGKTAEIAKTVAFLLSDGAGYITGQNIRVDGAIVKAL
HCCCCCHHHHEECCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEEECCEEEECC
>Mature Secondary Structure 
TVEKVALITAAGKGMGAAIARELAAGGYRVALMSPSGSAVALGDELGGFGIRGSVTEEA
CCHHEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCHH
DIDRLVQDTLARYGRIDAVVNNTGHPPKGDLLSITDDNWHAGLDLILLNVVRVMRRVTPV
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
FQQQGGGAVVNISSFAADAPEQPMPVSSALRAALSAWTRLYAERYAADNIRMNAVLPGFI
HHHCCCCEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHH
DSWPETPEIVARIPAGRFGKTAEIAKTVAFLLSDGAGYITGQNIRVDGAIVKAL
HCCCCCHHHHEECCCCCCCCHHHHHHHHHHHHCCCCCEEECCCEEECCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA