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The map label for this gene is intA [H]

Identifier: 189184591

GI number: 189184591

Start: 1709642

End: 1710841

Strand: Reverse

Name: intA [H]

Synonym: OTT_1684

Alternate gene names: 189184591

Gene position: 1710841-1709642 (Counterclockwise)

Preceding gene: 189184595

Following gene: 189184590

Centisome position: 85.16

GC content: 30.75

Gene sequence:

>1200_bases
ATGGAATCAATAATATTAACATTAAAGTTAACAGATAAGTTAATAAGAAAAATAAAAATTCCGACTGAAAGAACATCAAC
CATCAAGGATAAAATTGAACCAGGACTTCAACTAAGAATATCACGGTCAGGAAGAAAAACATGTTCTTTTGAAAAAAAAT
TTAGAAAAGAAGGGATAAAAATGACGATAGGGGTATTTCCAGATTTATCTATTAAAGAAGCTAGAAAAAAAGCAAGAGAA
TTAAAGAGATTAATGGCGAAAGGAATAGATCCAAGAGAAGAAAAACGTCAACAACAGATAGCAGAAGATGAGAAACGTCT
AAAAGCAAGACAAGATATTACATTCAAAGAGCTGTGTTATAAGTATATTGAAGAGTATGCCAAAATATATACTATATACT
GGCAGAAAGATACTGCAAGAATACATAATTATGCGAAACCGTTATTTTTAAAAAAGATAAGTGATATTAAAAGTAATGAT
ATTGAACAAATATTCAATGATATCAGCAAAGATGGAAAATATGCGACAGCAAATCAATTTCTAATAACCTTAAGCAGTAT
ATTTAATAAGGCAATAAAATGGGAATTAATAGACAGAAATCCTACACTAAAAATAGATAAACATAAAATGCAAGCAAGAG
AAAGACGTCTAAGTTACGATGAAATGAGTAAATTTTTACACGTATTATGTGGAGAAGCAACTCCATTGATAAGAGATTTT
GCATTACTAGCGTTATATACTGGAGCTAGAAAAACTAATGTGTTGGAGATGGAATGGGACAATATAGATTTTGTAAGAAA
AATATGGCATATACCAAAAACTAAGAATGGAAAGGCGCAAAATATACCATTAACAGATGAGATAATAGAAATATTGCAAG
CAAGGAAATTAACATCTAAAAGTAAATGGGTGCTATCAACTGATAAAAGCAAAAGCGGGCACTTGGAATATCCTTATAGA
GGATGGTATAAGATTTGTAAAAAGGCAGGCATAAAAAATTTAAGGATACACGATCTAAGAAGGACGTTTGCAAGTTGTAT
GGCAGATGAAGGCGCAGGTCAGTATATAATTAGCGCAGCATTGAATCATAGTGACATAAAATCAACGAGTATTTATACCA
AAGTTAGTTTAGAGCCAGTAAGGCAATATATGTCTAAGGTAACACAAATGATAAGCGACTGTTCAAAAATTGATATTTGA

Upstream 100 bases:

>100_bases
TACCTTGTTTAGGTAATTGTAATATAAATTAATATTGCAATTAATATGTTTAGGTAATTGTAATATAAATTAATATAACA
ATTCAATATGTGGAGTAATT

Downstream 100 bases:

>100_bases
AATAAATACTGAAATAACATGAAACTTAGCATGAGAAGAAATGCATATATGAAAACTAATTATCACAGGTAAAATCTGCG
TTTGAAGATGTTTAGCTAAT

Product: putative integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MESIILTLKLTDKLIRKIKIPTERTSTIKDKIEPGLQLRISRSGRKTCSFEKKFRKEGIKMTIGVFPDLSIKEARKKARE
LKRLMAKGIDPREEKRQQQIAEDEKRLKARQDITFKELCYKYIEEYAKIYTIYWQKDTARIHNYAKPLFLKKISDIKSND
IEQIFNDISKDGKYATANQFLITLSSIFNKAIKWELIDRNPTLKIDKHKMQARERRLSYDEMSKFLHVLCGEATPLIRDF
ALLALYTGARKTNVLEMEWDNIDFVRKIWHIPKTKNGKAQNIPLTDEIIEILQARKLTSKSKWVLSTDKSKSGHLEYPYR
GWYKICKKAGIKNLRIHDLRRTFASCMADEGAGQYIISAALNHSDIKSTSIYTKVSLEPVRQYMSKVTQMISDCSKIDI

Sequences:

>Translated_399_residues
MESIILTLKLTDKLIRKIKIPTERTSTIKDKIEPGLQLRISRSGRKTCSFEKKFRKEGIKMTIGVFPDLSIKEARKKARE
LKRLMAKGIDPREEKRQQQIAEDEKRLKARQDITFKELCYKYIEEYAKIYTIYWQKDTARIHNYAKPLFLKKISDIKSND
IEQIFNDISKDGKYATANQFLITLSSIFNKAIKWELIDRNPTLKIDKHKMQARERRLSYDEMSKFLHVLCGEATPLIRDF
ALLALYTGARKTNVLEMEWDNIDFVRKIWHIPKTKNGKAQNIPLTDEIIEILQARKLTSKSKWVLSTDKSKSGHLEYPYR
GWYKICKKAGIKNLRIHDLRRTFASCMADEGAGQYIISAALNHSDIKSTSIYTKVSLEPVRQYMSKVTQMISDCSKIDI
>Mature_399_residues
MESIILTLKLTDKLIRKIKIPTERTSTIKDKIEPGLQLRISRSGRKTCSFEKKFRKEGIKMTIGVFPDLSIKEARKKARE
LKRLMAKGIDPREEKRQQQIAEDEKRLKARQDITFKELCYKYIEEYAKIYTIYWQKDTARIHNYAKPLFLKKISDIKSND
IEQIFNDISKDGKYATANQFLITLSSIFNKAIKWELIDRNPTLKIDKHKMQARERRLSYDEMSKFLHVLCGEATPLIRDF
ALLALYTGARKTNVLEMEWDNIDFVRKIWHIPKTKNGKAQNIPLTDEIIEILQARKLTSKSKWVLSTDKSKSGHLEYPYR
GWYKICKKAGIKNLRIHDLRRTFASCMADEGAGQYIISAALNHSDIKSTSIYTKVSLEPVRQYMSKVTQMISDCSKIDI

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=353, Percent_Identity=23.7960339943343, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786748, Length=349, Percent_Identity=23.4957020057307, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI145693166, Length=351, Percent_Identity=21.9373219373219, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788690, Length=379, Percent_Identity=21.6358839050132, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 46598; Mature: 46598

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIILTLKLTDKLIRKIKIPTERTSTIKDKIEPGLQLRISRSGRKTCSFEKKFRKEGIK
CCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCE
MTIGVFPDLSIKEARKKARELKRLMAKGIDPREEKRQQQIAEDEKRLKARQDITFKELCY
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KYIEEYAKIYTIYWQKDTARIHNYAKPLFLKKISDIKSNDIEQIFNDISKDGKYATANQF
HHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEHHHH
LITLSSIFNKAIKWELIDRNPTLKIDKHKMQARERRLSYDEMSKFLHVLCGEATPLIRDF
HHHHHHHHHHHHEEEEECCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
ALLALYTGARKTNVLEMEWDNIDFVRKIWHIPKTKNGKAQNIPLTDEIIEILQARKLTSK
HHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
SKWVLSTDKSKSGHLEYPYRGWYKICKKAGIKNLRIHDLRRTFASCMADEGAGQYIISAA
CCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
LNHSDIKSTSIYTKVSLEPVRQYMSKVTQMISDCSKIDI
HCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MESIILTLKLTDKLIRKIKIPTERTSTIKDKIEPGLQLRISRSGRKTCSFEKKFRKEGIK
CCCEEEEEEHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCE
MTIGVFPDLSIKEARKKARELKRLMAKGIDPREEKRQQQIAEDEKRLKARQDITFKELCY
EEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
KYIEEYAKIYTIYWQKDTARIHNYAKPLFLKKISDIKSNDIEQIFNDISKDGKYATANQF
HHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEHHHH
LITLSSIFNKAIKWELIDRNPTLKIDKHKMQARERRLSYDEMSKFLHVLCGEATPLIRDF
HHHHHHHHHHHHEEEEECCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHH
ALLALYTGARKTNVLEMEWDNIDFVRKIWHIPKTKNGKAQNIPLTDEIIEILQARKLTSK
HHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
SKWVLSTDKSKSGHLEYPYRGWYKICKKAGIKNLRIHDLRRTFASCMADEGAGQYIISAA
CCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHH
LNHSDIKSTSIYTKVSLEPVRQYMSKVTQMISDCSKIDI
HCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]