Click here to switch to the map view.

The map label for this gene is dnaB [H]

Identifier: 189184434

GI number: 189184434

Start: 1556883

End: 1557215

Strand: Reverse

Name: dnaB [H]

Synonym: OTT_1527

Alternate gene names: 189184434

Gene position: 1557215-1556883 (Counterclockwise)

Preceding gene: 189184435

Following gene: 189184433

Centisome position: 77.51

GC content: 35.44

Gene sequence:

>333_bases
ATGGAAGTTGCTGAATCTCAATTGTCTATAGCTGTAGAACAAAGGTCAGATAAAAAGCCTATTCTCTCAGATCTGAAAGA
ATCAGGCTCAATTGAACAAGACTCAGATATTGTAATGTTCATATATCGGGACGAATATTACTTGTCTAGATCAGAACCAG
ATCTAGGTACTCCAGAACACATGGAATGGCAAGAAAAGCAAGATAGATGCTTTAATACTGCTGAAATAATTATTGCTAAA
CACCGTAATGGGCCAGTTGGTACAGTGAAGTTGCACTATAATATTAGGTATTCTAAATTTGGCAATATTGTTAAAAACTC
TCAGCAAGGTTAA

Upstream 100 bases:

>100_bases
ATCAAATTTTAAACCCATTCTTAGAGTGTGCTTTTGAAGCTCAAGGGTTTTCGTTTGAATTAGTTCAGTATAAGTAATTT
CAATAAAACTTAAGGGTGAT

Downstream 100 bases:

>100_bases
TAAACGCTAGATTATGCATAAGATGAAAAAATGCTGGTCAAAAAAAATTACAGCAAAATTTTACTCATTAACACCAGAGA
TATGCAATGTAAGGTTAGTT

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MEVAESQLSIAVEQRSDKKPILSDLKESGSIEQDSDIVMFIYRDEYYLSRSEPDLGTPEHMEWQEKQDRCFNTAEIIIAK
HRNGPVGTVKLHYNIRYSKFGNIVKNSQQG

Sequences:

>Translated_110_residues
MEVAESQLSIAVEQRSDKKPILSDLKESGSIEQDSDIVMFIYRDEYYLSRSEPDLGTPEHMEWQEKQDRCFNTAEIIIAK
HRNGPVGTVKLHYNIRYSKFGNIVKNSQQG
>Mature_110_residues
MEVAESQLSIAVEQRSDKKPILSDLKESGSIEQDSDIVMFIYRDEYYLSRSEPDLGTPEHMEWQEKQDRCFNTAEIIIAK
HRNGPVGTVKLHYNIRYSKFGNIVKNSQQG

Specific function: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with dnaC protein, primase, and other prepriming proteins [

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=100, Percent_Identity=50, Blast_Score=99, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 12707; Mature: 12707

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVAESQLSIAVEQRSDKKPILSDLKESGSIEQDSDIVMFIYRDEYYLSRSEPDLGTPEH
CCCCCCHHEEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCC
MEWQEKQDRCFNTAEIIIAKHRNGPVGTVKLHYNIRYSKFGNIVKNSQQG
CCHHHHHHHCCCCEEEEEEECCCCCEEEEEEEEEEEHHHHCHHHCCCCCC
>Mature Secondary Structure
MEVAESQLSIAVEQRSDKKPILSDLKESGSIEQDSDIVMFIYRDEYYLSRSEPDLGTPEH
CCCCCCHHEEEEECCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCEEEECCCCCCCCCCC
MEWQEKQDRCFNTAEIIIAKHRNGPVGTVKLHYNIRYSKFGNIVKNSQQG
CCHHHHHHHCCCCEEEEEEECCCCCEEEEEEEEEEEHHHHCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA