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The map label for this gene is intD [H]

Identifier: 189183655

GI number: 189183655

Start: 776683

End: 777801

Strand: Direct

Name: intD [H]

Synonym: OTT_0748

Alternate gene names: 189183655

Gene position: 776683-777801 (Clockwise)

Preceding gene: 189183654

Following gene: 189183656

Centisome position: 38.66

GC content: 33.24

Gene sequence:

>1119_bases
TTGGTAGTCCGTAGAGGAAGAGTAAGAAAAACATGGGTTTTAGAACAAAAATTTAAAAACCAGAGTTTAAAAATAACGAT
AGGGGAATTTCCATATTTATCTATTAAAAAAGCTAGAAAAATAGCAAGAGAATTAAAGACATTAATGGCGAACGGAATAG
ATCCAAGAGCAGTAAAACGTCAACAAAAGATAGAAGAAAATGAGAATCGTATAAAAGAAAGAGAAAGAAAAGCTAACGAT
ATTACATTCAAAGAGCTGTGTTATAGGTATATTGAAGAGTATGCCAAAATATATACTATAAACTGGGAAGAGTATACTGA
CAGAGTACATACTTATGCACAATCATTATATGGAAAAAAGATAAGCCAGATTCGAATGAGTGATATTCAACAAATATTCA
ATGATATCAGCAAAGAGGGAAAATATGCGACAGCAAATCTATTGCTAGCAACCTTACGCACTATGTTTAATAAGGCAATA
AAATGGGGATTAATAGAAAACAATCCTACTCTAGGAATAGAGCAGCATAAACTGCAAGCAAGAGAGAGACGTCTAAGTTA
CGATAAAATGGGTAGACTTTTACACGTATTATGTGGAGAAACAACTCCATTGATAAGAGATTTTGCATTACTAGCGTTAT
ATACTGGAGCTAGAAAAAGTAATGTATTAGAGATGGAATGGGACAATATAGATTTTGAAAGAAAAATATGGCATATACCA
AAAACTAAGAACGGAAAGGCGCAAAATATACCATTAACAGATGAGGCAATGGAAATATTGCAAGCAAGGAAATTCACATC
TGAAAGTAAATGGGTACTACCAAGTGCTACTAGCGAAAGTGGACACTTAGAGCGGCCAAATAACTCATGGCATAGGGTTT
GTAAAAAGGCTGGCATAAAAAATTTAAGGATACACGATCTAAGAAGGACGTTTGCAAGTTGTATGGGAGATGTAGGTGCA
AGTCAGAGGACAATTAGTATAGCATTGAATCATATTAGTCCAGAATCAACAATTAGTTATACTATACCTTGCCTGAAGTT
AGTACAAGAGTATATGTCTAAGGCTACACAAATAATTAATGGATGTGCTAGAAGTTATAATATTTATAATATTATCTGA

Upstream 100 bases:

>100_bases
AGTTTATAAAGCAGGTATTAAATAAAATTAACATTTCTGAGGGAAAAAAATAGAAATTATCCACGATCCAGATACAATAG
GACTTAAACTGAAAATCTCA

Downstream 100 bases:

>100_bases
CTAATATAAAAGTTGTGGTAAGAATAGTGCAACTTCATGTCGCACATGCATGTATGTAAACTAATTATTGCAGGTAAAAT
CTGTGTTTGAAGATGTTTAG

Product: putative integrase

Products: NA

Alternate protein names: Prophage QSR' integrase [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MVVRRGRVRKTWVLEQKFKNQSLKITIGEFPYLSIKKARKIARELKTLMANGIDPRAVKRQQKIEENENRIKERERKAND
ITFKELCYRYIEEYAKIYTINWEEYTDRVHTYAQSLYGKKISQIRMSDIQQIFNDISKEGKYATANLLLATLRTMFNKAI
KWGLIENNPTLGIEQHKLQARERRLSYDKMGRLLHVLCGETTPLIRDFALLALYTGARKSNVLEMEWDNIDFERKIWHIP
KTKNGKAQNIPLTDEAMEILQARKFTSESKWVLPSATSESGHLERPNNSWHRVCKKAGIKNLRIHDLRRTFASCMGDVGA
SQRTISIALNHISPESTISYTIPCLKLVQEYMSKATQIINGCARSYNIYNII

Sequences:

>Translated_372_residues
MVVRRGRVRKTWVLEQKFKNQSLKITIGEFPYLSIKKARKIARELKTLMANGIDPRAVKRQQKIEENENRIKERERKAND
ITFKELCYRYIEEYAKIYTINWEEYTDRVHTYAQSLYGKKISQIRMSDIQQIFNDISKEGKYATANLLLATLRTMFNKAI
KWGLIENNPTLGIEQHKLQARERRLSYDKMGRLLHVLCGETTPLIRDFALLALYTGARKSNVLEMEWDNIDFERKIWHIP
KTKNGKAQNIPLTDEAMEILQARKFTSESKWVLPSATSESGHLERPNNSWHRVCKKAGIKNLRIHDLRRTFASCMGDVGA
SQRTISIALNHISPESTISYTIPCLKLVQEYMSKATQIINGCARSYNIYNII
>Mature_372_residues
MVVRRGRVRKTWVLEQKFKNQSLKITIGEFPYLSIKKARKIARELKTLMANGIDPRAVKRQQKIEENENRIKERERKAND
ITFKELCYRYIEEYAKIYTINWEEYTDRVHTYAQSLYGKKISQIRMSDIQQIFNDISKEGKYATANLLLATLRTMFNKAI
KWGLIENNPTLGIEQHKLQARERRLSYDKMGRLLHVLCGETTPLIRDFALLALYTGARKSNVLEMEWDNIDFERKIWHIP
KTKNGKAQNIPLTDEAMEILQARKFTSESKWVLPSATSESGHLERPNNSWHRVCKKAGIKNLRIHDLRRTFASCMGDVGA
SQRTISIALNHISPESTISYTIPCLKLVQEYMSKATQIINGCARSYNIYNII

Specific function: Integrase from the cryptic lambdoic prophage DLP12. Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1786748, Length=282, Percent_Identity=24.822695035461, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788974, Length=327, Percent_Identity=23.2415902140673, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788690, Length=339, Percent_Identity=20.9439528023599, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 43363; Mature: 43363

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVRRGRVRKTWVLEQKFKNQSLKITIGEFPYLSIKKARKIARELKTLMANGIDPRAVKR
CCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QQKIEENENRIKERERKANDITFKELCYRYIEEYAKIYTINWEEYTDRVHTYAQSLYGKK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHH
ISQIRMSDIQQIFNDISKEGKYATANLLLATLRTMFNKAIKWGLIENNPTLGIEQHKLQA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCHHHHHHHH
RERRLSYDKMGRLLHVLCGETTPLIRDFALLALYTGARKSNVLEMEWDNIDFERKIWHIP
HHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHEEECC
KTKNGKAQNIPLTDEAMEILQARKFTSESKWVLPSATSESGHLERPNNSWHRVCKKAGIK
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCC
NLRIHDLRRTFASCMGDVGASQRTISIALNHISPESTISYTIPCLKLVQEYMSKATQIIN
CCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GCARSYNIYNII
HHHHCCCEEECC
>Mature Secondary Structure
MVVRRGRVRKTWVLEQKFKNQSLKITIGEFPYLSIKKARKIARELKTLMANGIDPRAVKR
CCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QQKIEENENRIKERERKANDITFKELCYRYIEEYAKIYTINWEEYTDRVHTYAQSLYGKK
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHH
ISQIRMSDIQQIFNDISKEGKYATANLLLATLRTMFNKAIKWGLIENNPTLGIEQHKLQA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCHHHHHHHH
RERRLSYDKMGRLLHVLCGETTPLIRDFALLALYTGARKSNVLEMEWDNIDFERKIWHIP
HHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHEEECC
KTKNGKAQNIPLTDEAMEILQARKFTSESKWVLPSATSESGHLERPNNSWHRVCKKAGIK
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCC
NLRIHDLRRTFASCMGDVGASQRTISIALNHISPESTISYTIPCLKLVQEYMSKATQIIN
CCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GCARSYNIYNII
HHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2553674; 2183007; 9278503 [H]