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The map label for this gene is tsf

Identifier: 189025831

GI number: 189025831

Start: 657708

End: 658580

Strand: Reverse

Name: tsf

Synonym: TPASS_0605

Alternate gene names: 189025831

Gene position: 658580-657708 (Counterclockwise)

Preceding gene: 189025832

Following gene: 189025830

Centisome position: 57.8

GC content: 55.96

Gene sequence:

>873_bases
ATGGAGATTGCTGCTCGCGACGTTAAGTCTTTGCGTGATAAAACCGGGGCCGGGATGATGGAGTGTAAGCGTGCGCTCCA
GGAGTGTGCAGGGGACGCTCTGTGTGCAGAAAAGTATCTTAAGGAGAGGGGGCTTGCTGCCATCGAAAACAGGCGTGGGC
GTGCCACTGCTGAGGGAGTCATCGTTATTAAAGCACGGCATGCAGAGGGCGCGGCCTGTGGGGCGAGCGCTGTAGCAATG
GTTGAGCTTGTTTGCGAAACAGATTTTGTGGCAAAGAACGCAGAGTTCATCGCCCTTGCTGAGCGTATAGCTCAGGCGGT
GCTCGAGCACGCGTACACTGAGGTAAACCAGGTSCTGCGCGATATGGTGGTGGACCTCGCAACGCGCGTACGGGAAAATA
TGAGCTTGACGCGCCTTGCGCTCTTACGTGCCGGCAGTGCCGGTGCAGGTCAGTACCTTTCTCACTACGTGCACCCTGAT
AAAAAAACAGGGGTAGTGCTCTCCTTTTCCTCCGATGCGCCGGATGTGTTCCTGCGATCCGATGTGCGGGCCTTCGCGTA
TGACTGCTGTTTGCACGCGGCGGCATATACCCCTCGCTACGTGCGCGCAGAGGACGTGCCTGCTGAGTATGTGCGGGAGC
AGCGTGAGGTGTTCCAAGCGCATGTTGCGTCTCTCCAGAAGCCTGCGCATGTCAAGGAAAGTATCGTGCAGGGTAAACTA
GAGAAGCATTTGGCTGAGATCTGTTTTCTGAAGCAGCCCTTTGTTAAGGACGACAAGCTTTCTGTTGAAAAAAAGATGGC
AGAAGTGGGTGCCCGCGCAGGGGGTGCGCTTCGGTTTACTCAGGCACTGATATACCAGCTAGGGGTACAGTGA

Upstream 100 bases:

>100_bases
GGGGCGTTAGGTGTGCCCTCCGCGGTCTCTTTTGGGATGTGTGTCTGGGTAGGCATGTTTGCATCGAAGTCTGATCGGAA
AATGCTGTCAGGAGGGGTAC

Downstream 100 bases:

>100_bases
GTGGGAAGCACGGATAGATCCTGCCACCCTGCAGGATGGGGAGCAAGCAGGCGTGGGGGAGCTCGTGCTTCTCTCTTGCC
GCACTGTGTTGTGAGGGGAA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MEIAARDVKSLRDKTGAGMMECKRALQECAGDALCAEKYLKERGLAAIENRRGRATAEGVIVIKARHAEGAACGASAVAM
VELVCETDFVAKNAEFIALAERIAQAVLEHAYTEVNQVLRDMVVDLATRVRENMSLTRLALLRAGSAGAGQYLSHYVHPD
KKTGVVLSFSSDAPDVFLRSDVRAFAYDCCLHAAAYTPRYVRAEDVPAEYVREQREVFQAHVASLQKPAHVKESIVQGKL
EKHLAEICFLKQPFVKDDKLSVEKKMAEVGARAGGALRFTQALIYQLGVQ

Sequences:

>Translated_290_residues
MEIAARDVKSLRDKTGAGMMECKRALQECAGDALCAEKYLKERGLAAIENRRGRATAEGVIVIKARHAEGAACGASAVAM
VELVCETDFVAKNAEFIALAERIAQAVLEHAYTEVNQVLRDMVVDLATRVRENMSLTRLALLRAGSAGAGQYLSHYVHPD
KKTGVVLSFSSDAPDVFLRSDVRAFAYDCCLHAAAYTPRYVRAEDVPAEYVREQREVFQAHVASLQKPAHVKESIVQGKL
EKHLAEICFLKQPFVKDDKLSVEKKMAEVGARAGGALRFTQALIYQLGVQ
>Mature_290_residues
MEIAARDVKSLRDKTGAGMMECKRALQECAGDALCAEKYLKERGLAAIENRRGRATAEGVIVIKARHAEGAACGASAVAM
VELVCETDFVAKNAEFIALAERIAQAVLEHAYTEVNQVLRDMVVDLATRVRENMSLTRLALLRAGSAGAGQYLSHYVHPD
KKTGVVLSFSSDAPDVFLRSDVRAFAYDCCLHAAAYTPRYVRAEDVPAEYVREQREVFQAHVASLQKPAHVKESIVQGKL
EKHLAEICFLKQPFVKDDKLSVEKKMAEVGARAGGALRFTQALIYQLGVQ

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=177, Percent_Identity=29.3785310734463, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786366, Length=282, Percent_Identity=31.2056737588652, Blast_Score=121, Evalue=4e-29,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_TREPA (O83614)

Other databases:

- EMBL:   AE000520
- PIR:   G71304
- RefSeq:   NP_219043.1
- ProteinModelPortal:   O83614
- SMR:   O83614
- IntAct:   O83614
- GeneID:   2611557
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0605
- NMPDR:   fig|243276.1.peg.602
- TIGR:   TP_0605
- HOGENOM:   HBG713289
- OMA:   NVEYVSI
- ProtClustDB:   PRK09377
- BioCyc:   TPAL243276:TP_0605-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31783; Mature: 31783

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIAARDVKSLRDKTGAGMMECKRALQECAGDALCAEKYLKERGLAAIENRRGRATAEGV
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCE
IVIKARHAEGAACGASAVAMVELVCETDFVAKNAEFIALAERIAQAVLEHAYTEVNQVLR
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMVVDLATRVRENMSLTRLALLRAGSAGAGQYLSHYVHPDKKTGVVLSFSSDAPDVFLRS
HHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DVRAFAYDCCLHAAAYTPRYVRAEDVPAEYVREQREVFQAHVASLQKPAHVKESIVQGKL
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EKHLAEICFLKQPFVKDDKLSVEKKMAEVGARAGGALRFTQALIYQLGVQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIAARDVKSLRDKTGAGMMECKRALQECAGDALCAEKYLKERGLAAIENRRGRATAEGV
CCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCE
IVIKARHAEGAACGASAVAMVELVCETDFVAKNAEFIALAERIAQAVLEHAYTEVNQVLR
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMVVDLATRVRENMSLTRLALLRAGSAGAGQYLSHYVHPDKKTGVVLSFSSDAPDVFLRS
HHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHH
DVRAFAYDCCLHAAAYTPRYVRAEDVPAEYVREQREVFQAHVASLQKPAHVKESIVQGKL
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EKHLAEICFLKQPFVKDDKLSVEKKMAEVGARAGGALRFTQALIYQLGVQ
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876