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The map label for this gene is dxr [H]

Identifier: 189025827

GI number: 189025827

Start: 654374

End: 655525

Strand: Reverse

Name: dxr [H]

Synonym: TPASS_0601

Alternate gene names: 189025827

Gene position: 655525-654374 (Counterclockwise)

Preceding gene: 189025828

Following gene: 189025826

Centisome position: 57.53

GC content: 52.52

Gene sequence:

>1152_bases
GTGTTTTGGGATCGCTGCAGTATGAGTGTGCGACGTGTGGTAGTGCTGGGCATTACTGGTTCTATTGGAGCTGCAGCACT
CAAACTTCTGCGTCGGTTTCCCGATCGGTTCTTGCTGGTGGGCGCTTCAGGTCACCGGCAGACCGAGTACGCGCGGGCGT
TGGCGCGCGAGTTCTCTTTATCAGATATCACTATGACTGGCTCATGTTCTGAGCAAGAAGGTCGCGCACGCATAAAGCGT
CTGCTTTCTTCCTGTGAAGCAGAGGTGGTGGTAAACGGTATTGCCGGCGCTGCTGGTCTTTTTGCCTCTCTTGAGGTGCT
CAAGACGCGTTGTACGCTCGCGTTAGCAAATAAAGAAAGTGTGGTACTTGCAGCTTCTCTTTTGCATGCTGCGGCACGCG
AAAGTGGGGCAACAATCGTTCCTGTAGATTCAGAGCATGCTGCTATTTTTCAACTTATTGCAGCGCACGGCGCGCATGCG
GTGGCGCAGGTAGTGCTCACTGCGTCAGGTGGTCCATTTAGAACCTTTTCAAAGGAGTGCTTAGCGCATGTCACGGTGGA
AGATGCGCTTCAACATCCGACGTGGCGTATGGGGAAGAAGATTTCTGTTGATTCTGCAACACTTGCAAATAAGGCACTGG
AAGTTATAGAAGCAGTGCAGTTTTTTCGTATACCGGTGGATCGGGTCACGGTGGTGGTGCACCCTCAGAGCATAGTGCAT
GCGCTGGTGCAATGTCATTCGGGAGAAACGTATGCGCAGCTTTCTGTCCCTGATATGGCGTCGCCGTTACTGTATGCGTT
GCTGTACCCTGATGCGCCTCCTGCGTATCAAACTCCGCTTGATTTTACATCGGGACTGTCTTTGCATTTTGAACCTCCGA
GGGTAGATGACTTTCCGCTGTTGCGTATGGGTTTTGATGTTGCACGGGCGCAGCGTGCGTATCCTATTGCCTTTAATGCA
GCAAATGAGGAGGCGGTGCGTGCGTTCTTGCAAAGAAACATTGGGTTTTTAGATATCGCACACGTGACTGCACAGGCGTT
GCAAGAAGATTGGCGCGCAATTCCCCAAACGTTTGAAGAAGTTATGGCGTGCGATACGCGTGCGCGGATGTGTGCGCGGA
CGTGCATTGCACAGAGGTGGAGAGAGAGGTGA

Upstream 100 bases:

>100_bases
AGGTAAAGGATTCAGGATTTTTTACCCCCGGGCGGGGCGGAATTATGGATAACCTGGATTCGCTTGCGCCGTCACTGGGG
ACTTTTTACATTGCATGTGA

Downstream 100 bases:

>100_bases
TTAAGATAATTATTGGCGTTGTGGTGCTTGGTATTGTGGTGTTGTTTCATGAACTGGGGCATTTTGTCGCCGCGCTTTGG
TGTCGAGTGGAGGTGCTCAG

Product: 1-deoxy-D-xylulose 5-phosphate reductoisomerase

Products: NA

Alternate protein names: DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MFWDRCSMSVRRVVVLGITGSIGAAALKLLRRFPDRFLLVGASGHRQTEYARALAREFSLSDITMTGSCSEQEGRARIKR
LLSSCEAEVVVNGIAGAAGLFASLEVLKTRCTLALANKESVVLAASLLHAAARESGATIVPVDSEHAAIFQLIAAHGAHA
VAQVVLTASGGPFRTFSKECLAHVTVEDALQHPTWRMGKKISVDSATLANKALEVIEAVQFFRIPVDRVTVVVHPQSIVH
ALVQCHSGETYAQLSVPDMASPLLYALLYPDAPPAYQTPLDFTSGLSLHFEPPRVDDFPLLRMGFDVARAQRAYPIAFNA
ANEEAVRAFLQRNIGFLDIAHVTAQALQEDWRAIPQTFEEVMACDTRARMCARTCIAQRWRER

Sequences:

>Translated_383_residues
MFWDRCSMSVRRVVVLGITGSIGAAALKLLRRFPDRFLLVGASGHRQTEYARALAREFSLSDITMTGSCSEQEGRARIKR
LLSSCEAEVVVNGIAGAAGLFASLEVLKTRCTLALANKESVVLAASLLHAAARESGATIVPVDSEHAAIFQLIAAHGAHA
VAQVVLTASGGPFRTFSKECLAHVTVEDALQHPTWRMGKKISVDSATLANKALEVIEAVQFFRIPVDRVTVVVHPQSIVH
ALVQCHSGETYAQLSVPDMASPLLYALLYPDAPPAYQTPLDFTSGLSLHFEPPRVDDFPLLRMGFDVARAQRAYPIAFNA
ANEEAVRAFLQRNIGFLDIAHVTAQALQEDWRAIPQTFEEVMACDTRARMCARTCIAQRWRER
>Mature_383_residues
MFWDRCSMSVRRVVVLGITGSIGAAALKLLRRFPDRFLLVGASGHRQTEYARALAREFSLSDITMTGSCSEQEGRARIKR
LLSSCEAEVVVNGIAGAAGLFASLEVLKTRCTLALANKESVVLAASLLHAAARESGATIVPVDSEHAAIFQLIAAHGAHA
VAQVVLTASGGPFRTFSKECLAHVTVEDALQHPTWRMGKKISVDSATLANKALEVIEAVQFFRIPVDRVTVVVHPQSIVH
ALVQCHSGETYAQLSVPDMASPLLYALLYPDAPPAYQTPLDFTSGLSLHFEPPRVDDFPLLRMGFDVARAQRAYPIAFNA
ANEEAVRAFLQRNIGFLDIAHVTAQALQEDWRAIPQTFEEVMACDTRARMCARTCIAQRWRER

Specific function: Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) [H]

COG id: COG0743

COG function: function code I; 1-deoxy-D-xylulose 5-phosphate reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DXR family [H]

Homologues:

Organism=Escherichia coli, GI1786369, Length=392, Percent_Identity=35.4591836734694, Blast_Score=211, Evalue=7e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003821
- InterPro:   IPR013644
- InterPro:   IPR013512
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08436 DXP_redisom_C; PF02670 DXP_reductoisom [H]

EC number: =1.1.1.267 [H]

Molecular weight: Translated: 41879; Mature: 41879

Theoretical pI: Translated: 7.78; Mature: 7.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFWDRCSMSVRRVVVLGITGSIGAAALKLLRRFPDRFLLVGASGHRQTEYARALAREFSL
CCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCC
SDITMTGSCSEQEGRARIKRLLSSCEAEVVVNGIAGAAGLFASLEVLKTRCTLALANKES
CCEEEECCCCCHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHHHHHHHHHHHHEEECCCCH
VVLAASLLHAAARESGATIVPVDSEHAAIFQLIAAHGAHAVAQVVLTASGGPFRTFSKEC
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCHHHHHHHHEECCCCCCHHHHHHH
LAHVTVEDALQHPTWRMGKKISVDSATLANKALEVIEAVQFFRIPVDRVTVVVHPQSIVH
HHHHHHHHHHCCCCHHCCCEECCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCHHHHH
ALVQCHSGETYAQLSVPDMASPLLYALLYPDAPPAYQTPLDFTSGLSLHFEPPRVDDFPL
HHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCH
LRMGFDVARAQRAYPIAFNAANEEAVRAFLQRNIGFLDIAHVTAQALQEDWRAIPQTFEE
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHH
VMACDTRARMCARTCIAQRWRER
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFWDRCSMSVRRVVVLGITGSIGAAALKLLRRFPDRFLLVGASGHRQTEYARALAREFSL
CCCCHHHHHEEEEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCC
SDITMTGSCSEQEGRARIKRLLSSCEAEVVVNGIAGAAGLFASLEVLKTRCTLALANKES
CCEEEECCCCCHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHHHHHHHHHHHHEEECCCCH
VVLAASLLHAAARESGATIVPVDSEHAAIFQLIAAHGAHAVAQVVLTASGGPFRTFSKEC
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCHHHHHHHHEECCCCCCHHHHHHH
LAHVTVEDALQHPTWRMGKKISVDSATLANKALEVIEAVQFFRIPVDRVTVVVHPQSIVH
HHHHHHHHHHCCCCHHCCCEECCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEECCHHHHH
ALVQCHSGETYAQLSVPDMASPLLYALLYPDAPPAYQTPLDFTSGLSLHFEPPRVDDFPL
HHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCH
LRMGFDVARAQRAYPIAFNAANEEAVRAFLQRNIGFLDIAHVTAQALQEDWRAIPQTFEE
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHH
VMACDTRARMCARTCIAQRWRER
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]