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The map label for this gene is mdtN [H]

Identifier: 188586552

GI number: 188586552

Start: 2041175

End: 2042563

Strand: Reverse

Name: mdtN [H]

Synonym: Nther_1938

Alternate gene names: 188586552

Gene position: 2042563-2041175 (Counterclockwise)

Preceding gene: 188586553

Following gene: 188586551

Centisome position: 64.52

GC content: 38.37

Gene sequence:

>1389_bases
ATGTCTAAACAAAACCAGCAGATACAAAAACAAAAGTCTTCAGGTACAGATACAGAGGCTCAAAACAAAAAAGCAACTTA
CAATCAAGAGTCAAAAATTAGAACTTGGTTTAACAAAAATAAAAAAATAGTAAGTGGAGTGCTTTTAATAGTTTTAGTTC
TGGCTGTTGGGTATTTGAATCGGGATTTGTTCTTTGAAGAGGAAATAGTTGTTGAAGAAGAACGCCCTTTAGTAGAAGTG
ACCAATCCTGAAATACAGGATATCGAAAAAAAAGCCACAGTAATAGGAAGTGTAGATCCTACAGAAAGAAGGATTATAGT
TCCGGAAGTTGCAGGTGAAGTGAAATCTCTTTATGTAGAAGAAGGAGACTATGTTAGCCATGGTGATTTATTAATGGAAC
TAGATGATGGCGATTATCAACTTCAATTGGAAGAAGCTCAGGCAAACTTAGATGGAGCTAAAGCACAACTCGAAAATGCT
AAAAAGGGTGCTAGAACGGGAGAAAGAAAAGAAGCTGAAACTAGTGTTGAAAGAGCCAGAGAAGCGAAAGAGCAAATGGA
AAGGGAATTAGAAAGAGTAGAAACATTACATCAGGACGGTTATGCCTCAGATCAAGAACTGGAACAGATGACTTTACAGT
ACAAAAATGCAAAAGAGCAACTGAGGGCTGCTGAAGGCTATAAACAATCAGTTGAAGAAGGAGCTAGGGACGAAGAGTTA
GATGCCTTGCGATCCCAGATAAAAAGGGCTGAAACAGGGGTAAAATTAGCTGAAAGAATGATTGATCGGACTAAAATCAC
AGCTCCTGTAGATGGTGAAATTACTATGGTTGATGCCGAAGAGGGAGAACTAGTTGGTTCCGAATCCCCTGCCTTTGTAA
TGCTAGATCCGGATAGCTACCAGGTGTTGGCTGGCTTACCTGAGTCTTATGTAAACCAGGTTAGTGATGGAGAAACTGTC
GATGTTAAAATTCCATCTGCTTTAGATGAAGAGTTTGAAGGAATGATACATCACGTTGGTCAATTGCCTCCAGAAGAAAA
TGCTAAGGGATATCCTATGGAAATAGAGTTAACACCTGAGATAGAAAAACAAGTACGGGCTGGAATGTATACTCAAGTAA
ATGTGACTATAGAAAAATCTGAAGATGCTCTAGCAATACCTCAACATGCAGTTGTAGAGGAAGAGGGAGAAACAGGAGTG
TTCATAGTTGATGAAAGTACAGAAAATCAACAAGTACAATTTATCGAGGTAAAAACAGGAATTAATGAAGACGGTTACAT
TGAAATCGTTTCAGGTCTATCTGAAGATGATTTAGTCATAATAGAGGGCTTTCAAGAAATTGAACAAGGTATCAGAGTAG
ATGCGACAGAAATGGGTGATGATTCATGA

Upstream 100 bases:

>100_bases
ATAATGATCCAGCTCAAAACGATGGTTTAAATAATAATGGATTTGACAGTAATGGCGATGGGTTCAGAAAAAATTAGTTT
TAGTGATTGGAGGAATAATT

Downstream 100 bases:

>100_bases
ATCTTGCAGGTATAGGAATAAAGCAACCTATTGGAGTTTTAATGGTTGTAATTGGGGTAATATTAATAGGATTTATTGCT
GTTTCAGAAACACCAATCGA

Product: efflux transporter, RND family, MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSKQNQQIQKQKSSGTDTEAQNKKATYNQESKIRTWFNKNKKIVSGVLLIVLVLAVGYLNRDLFFEEEIVVEEERPLVEV
TNPEIQDIEKKATVIGSVDPTERRIIVPEVAGEVKSLYVEEGDYVSHGDLLMELDDGDYQLQLEEAQANLDGAKAQLENA
KKGARTGERKEAETSVERAREAKEQMERELERVETLHQDGYASDQELEQMTLQYKNAKEQLRAAEGYKQSVEEGARDEEL
DALRSQIKRAETGVKLAERMIDRTKITAPVDGEITMVDAEEGELVGSESPAFVMLDPDSYQVLAGLPESYVNQVSDGETV
DVKIPSALDEEFEGMIHHVGQLPPEENAKGYPMEIELTPEIEKQVRAGMYTQVNVTIEKSEDALAIPQHAVVEEEGETGV
FIVDESTENQQVQFIEVKTGINEDGYIEIVSGLSEDDLVIIEGFQEIEQGIRVDATEMGDDS

Sequences:

>Translated_462_residues
MSKQNQQIQKQKSSGTDTEAQNKKATYNQESKIRTWFNKNKKIVSGVLLIVLVLAVGYLNRDLFFEEEIVVEEERPLVEV
TNPEIQDIEKKATVIGSVDPTERRIIVPEVAGEVKSLYVEEGDYVSHGDLLMELDDGDYQLQLEEAQANLDGAKAQLENA
KKGARTGERKEAETSVERAREAKEQMERELERVETLHQDGYASDQELEQMTLQYKNAKEQLRAAEGYKQSVEEGARDEEL
DALRSQIKRAETGVKLAERMIDRTKITAPVDGEITMVDAEEGELVGSESPAFVMLDPDSYQVLAGLPESYVNQVSDGETV
DVKIPSALDEEFEGMIHHVGQLPPEENAKGYPMEIELTPEIEKQVRAGMYTQVNVTIEKSEDALAIPQHAVVEEEGETGV
FIVDESTENQQVQFIEVKTGINEDGYIEIVSGLSEDDLVIIEGFQEIEQGIRVDATEMGDDS
>Mature_461_residues
SKQNQQIQKQKSSGTDTEAQNKKATYNQESKIRTWFNKNKKIVSGVLLIVLVLAVGYLNRDLFFEEEIVVEEERPLVEVT
NPEIQDIEKKATVIGSVDPTERRIIVPEVAGEVKSLYVEEGDYVSHGDLLMELDDGDYQLQLEEAQANLDGAKAQLENAK
KGARTGERKEAETSVERAREAKEQMERELERVETLHQDGYASDQELEQMTLQYKNAKEQLRAAEGYKQSVEEGARDEELD
ALRSQIKRAETGVKLAERMIDRTKITAPVDGEITMVDAEEGELVGSESPAFVMLDPDSYQVLAGLPESYVNQVSDGETVD
VKIPSALDEEFEGMIHHVGQLPPEENAKGYPMEIELTPEIEKQVRAGMYTQVNVTIEKSEDALAIPQHAVVEEEGETGVF
IVDESTENQQVQFIEVKTGINEDGYIEIVSGLSEDDLVIIEGFQEIEQGIRVDATEMGDDS

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790519, Length=237, Percent_Identity=25.3164556962025, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081796, Length=359, Percent_Identity=24.2339832869081, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788711, Length=320, Percent_Identity=25.9375, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 51660; Mature: 51529

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQNQQIQKQKSSGTDTEAQNKKATYNQESKIRTWFNKNKKIVSGVLLIVLVLAVGYLN
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
RDLFFEEEIVVEEERPLVEVTNPEIQDIEKKATVIGSVDPTERRIIVPEVAGEVKSLYVE
CCCEECCCEEEECCCCEEEECCCHHHHHHHHHHEECCCCCCCCEEECHHHHHHHHHHEEC
EGDYVSHGDLLMELDDGDYQLQLEEAQANLDGAKAQLENAKKGARTGERKEAETSVERAR
CCCEEECCCEEEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EAKEQMERELERVETLHQDGYASDQELEQMTLQYKNAKEQLRAAEGYKQSVEEGARDEEL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DALRSQIKRAETGVKLAERMIDRTKITAPVDGEITMVDAEEGELVGSESPAFVMLDPDSY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEECCCCCEEEEECCCCC
QVLAGLPESYVNQVSDGETVDVKIPSALDEEFEGMIHHVGQLPPEENAKGYPMEIELTPE
EEECCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCH
IEKQVRAGMYTQVNVTIEKSEDALAIPQHAVVEEEGETGVFIVDESTENQQVQFIEVKTG
HHHHHHCCCEEEEEEEEECCCCCEECCCHHHCCCCCCCCEEEEECCCCCCEEEEEEEECC
INEDGYIEIVSGLSEDDLVIIEGFQEIEQGIRVDATEMGDDS
CCCCCEEEEECCCCCCCEEEEECHHHHHCCCEECCCCCCCCC
>Mature Secondary Structure 
SKQNQQIQKQKSSGTDTEAQNKKATYNQESKIRTWFNKNKKIVSGVLLIVLVLAVGYLN
CCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
RDLFFEEEIVVEEERPLVEVTNPEIQDIEKKATVIGSVDPTERRIIVPEVAGEVKSLYVE
CCCEECCCEEEECCCCEEEECCCHHHHHHHHHHEECCCCCCCCEEECHHHHHHHHHHEEC
EGDYVSHGDLLMELDDGDYQLQLEEAQANLDGAKAQLENAKKGARTGERKEAETSVERAR
CCCEEECCCEEEEECCCCEEEEEEHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EAKEQMERELERVETLHQDGYASDQELEQMTLQYKNAKEQLRAAEGYKQSVEEGARDEEL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DALRSQIKRAETGVKLAERMIDRTKITAPVDGEITMVDAEEGELVGSESPAFVMLDPDSY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEECCCCCEEEEECCCCC
QVLAGLPESYVNQVSDGETVDVKIPSALDEEFEGMIHHVGQLPPEENAKGYPMEIELTPE
EEECCCCHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCH
IEKQVRAGMYTQVNVTIEKSEDALAIPQHAVVEEEGETGVFIVDESTENQQVQFIEVKTG
HHHHHHCCCEEEEEEEEECCCCCEECCCHHHCCCCCCCCEEEEECCCCCCEEEEEEEECC
INEDGYIEIVSGLSEDDLVIIEGFQEIEQGIRVDATEMGDDS
CCCCCEEEEECCCCCCCEEEEECHHHHHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]