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The map label for this gene is yqiR [H]

Identifier: 188586525

GI number: 188586525

Start: 2005534

End: 2007267

Strand: Reverse

Name: yqiR [H]

Synonym: Nther_1911

Alternate gene names: 188586525

Gene position: 2007267-2005534 (Counterclockwise)

Preceding gene: 188586527

Following gene: 188586524

Centisome position: 63.41

GC content: 35.24

Gene sequence:

>1734_bases
ATGACTAATTTACAAAATTCAGATTTAGAAATTATTTTAGATTCAGTCTATAACGGAATTATTGCAATTAATAAAGAAGG
CGAAATTAATCTCTTTAATAAATCAGCTAGTGAAATTCTAGGGATGTCAAAAGAAGAAGTTTTGGGGTGCGATATCAGAG
AAATTATACCAGAAACTGGGCTTTTTAAAGTTTTGGAGAGTAGTCAGACTTTTACAACGGAGAAATTTGTCGTAAATAAA
AAAACTTTACTTACAAATCGCTCTCCCATCTTTAAAGAAGGGGAACTTATTGGAGCTCTGGGAATTTTTCAAGATATTTC
CGAATTGGAACATATATCTCAAGAACTTGCCAAAACAAAGGCAATAAATGACGAGTTAAGGGCAATTATCGAATCTTCTT
ATGATGGTTTCTGGATAACAGATGGTGAAGGCTATACTATCATGATAAATAGCTCTTACGAGCGTATTTCTGGTGCCAAA
GCAGAAGAAGTAGTAGGAAGACATATGAAGGAATTGGAAGAAGAAGGATTTTGCTCGGAATCTGTAACTTTAAAAGTACT
AGAACAAAAAGAACGGGTAACATTAATGCACGAACTATTTTCTGGAAAAAAAGTCATGGTTACTGGTAATCCTGTGTTTG
ATAGTGATGGAAATATCACTAAAGTAGTAACTAATGTCAGAGATATTTCAGAATTACTTGAATTAAAAGATGAGCTAGAA
AAAACTCAAGCTCTTACTCGCCATTATAAAGAAAAGCTAACTGAAATGGAAGAAAAACTAGGAGAAGGTGAAATTGTAGC
AAAAAGCAAGGTGAAAAAACGGTTGCTAGCTCAAGCTGCTAGAGTTGCAGCTTTTGATTCTACTGTTTTAATTACAGGAG
AAACAGGAGTTGGTAAAGAAATAGTAGCTAAATACATTCATCAAAACAGCAATCGCAGCGAGCAACCTTTCATAAAAATT
AACTGTGGAGCCATACCCGAAAACTTGCTTGAATCTGAACTATTTGGACATGAACCAGGATCTTTCACAGGTGCATCTAA
AAACGGAAAACCGGGTAAATTTGAAATTGCCAATGGGGGAACACTGCTACTTGATGAGATAGGTGAATTATCTAAAGATT
TACAAGTTAAGCTATTAAGAGCACTACAAGATCAAGAGATAACTAGAATTGGAGGGGTTAAACCCCGACAATTAGATGTG
AAAATCATTGCTTGTACCAATCGAGATTTAGAAGAAATGGTCTCTCAGGGAGAATTTAGAGAAGACTTGTACTATCGTTT
GAGCGTGGTGCCATTGTATATACCACCCTTGAGAGAACGCCCAGATGATATACCTTTTTTAATTCGTCATTATATTAGAA
AATATAATGAAAAATACGGTGTTAATAAGGGATTGTCCTCTTCTGCTTTGGAAGAATTAGTGTCTTATAATTGGCCGGGG
AACGTTCGAGAGTTAGAAAATATGATAGAGCGACTAGTTATCATGGTACCTGAAAACTTAATTGAAACTTCAGATCTCCC
ACAACAAATTAAAGAAAGTAATGTCAAAATCTTAGAGAACTTATCTTTACCTGATGCCGTTAGCAAGCTTGAAAAGCGAA
TGCTTCAAAAAGCTATGGAACAGTCGAACAATACCAGGGAAGCAGCCCAAATTTTAGGTGTAGCTCAGTCAACTGTTGTG
AGAAAGTTAGACAAGTATGGATTGAATTACAAACATGATGATCAAGCAAACTAA

Upstream 100 bases:

>100_bases
GTTTTGATTTCTGTCTAAAACTATCTTAACTCCGGGACGGAGACTGATTCAAATATCATATAACTTAACAGAACTAAGAA
ATTCGGGGGGAGGGGTTTCT

Downstream 100 bases:

>100_bases
TATAAAATCTATCGAACTAAAATATAATTTTTGATGCGCAACTCGAATAATTTGATGCAAAATCGAATCGAAAATTGTAG
GCTAATATAATGATTAAATT

Product: PAS modulated sigma54 specific transcriptional regulator, Fis family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 576

Protein sequence:

>577_residues
MTNLQNSDLEIILDSVYNGIIAINKEGEINLFNKSASEILGMSKEEVLGCDIREIIPETGLFKVLESSQTFTTEKFVVNK
KTLLTNRSPIFKEGELIGALGIFQDISELEHISQELAKTKAINDELRAIIESSYDGFWITDGEGYTIMINSSYERISGAK
AEEVVGRHMKELEEEGFCSESVTLKVLEQKERVTLMHELFSGKKVMVTGNPVFDSDGNITKVVTNVRDISELLELKDELE
KTQALTRHYKEKLTEMEEKLGEGEIVAKSKVKKRLLAQAARVAAFDSTVLITGETGVGKEIVAKYIHQNSNRSEQPFIKI
NCGAIPENLLESELFGHEPGSFTGASKNGKPGKFEIANGGTLLLDEIGELSKDLQVKLLRALQDQEITRIGGVKPRQLDV
KIIACTNRDLEEMVSQGEFREDLYYRLSVVPLYIPPLRERPDDIPFLIRHYIRKYNEKYGVNKGLSSSALEELVSYNWPG
NVRELENMIERLVIMVPENLIETSDLPQQIKESNVKILENLSLPDAVSKLEKRMLQKAMEQSNNTREAAQILGVAQSTVV
RKLDKYGLNYKHDDQAN

Sequences:

>Translated_577_residues
MTNLQNSDLEIILDSVYNGIIAINKEGEINLFNKSASEILGMSKEEVLGCDIREIIPETGLFKVLESSQTFTTEKFVVNK
KTLLTNRSPIFKEGELIGALGIFQDISELEHISQELAKTKAINDELRAIIESSYDGFWITDGEGYTIMINSSYERISGAK
AEEVVGRHMKELEEEGFCSESVTLKVLEQKERVTLMHELFSGKKVMVTGNPVFDSDGNITKVVTNVRDISELLELKDELE
KTQALTRHYKEKLTEMEEKLGEGEIVAKSKVKKRLLAQAARVAAFDSTVLITGETGVGKEIVAKYIHQNSNRSEQPFIKI
NCGAIPENLLESELFGHEPGSFTGASKNGKPGKFEIANGGTLLLDEIGELSKDLQVKLLRALQDQEITRIGGVKPRQLDV
KIIACTNRDLEEMVSQGEFREDLYYRLSVVPLYIPPLRERPDDIPFLIRHYIRKYNEKYGVNKGLSSSALEELVSYNWPG
NVRELENMIERLVIMVPENLIETSDLPQQIKESNVKILENLSLPDAVSKLEKRMLQKAMEQSNNTREAAQILGVAQSTVV
RKLDKYGLNYKHDDQAN
>Mature_576_residues
TNLQNSDLEIILDSVYNGIIAINKEGEINLFNKSASEILGMSKEEVLGCDIREIIPETGLFKVLESSQTFTTEKFVVNKK
TLLTNRSPIFKEGELIGALGIFQDISELEHISQELAKTKAINDELRAIIESSYDGFWITDGEGYTIMINSSYERISGAKA
EEVVGRHMKELEEEGFCSESVTLKVLEQKERVTLMHELFSGKKVMVTGNPVFDSDGNITKVVTNVRDISELLELKDELEK
TQALTRHYKEKLTEMEEKLGEGEIVAKSKVKKRLLAQAARVAAFDSTVLITGETGVGKEIVAKYIHQNSNRSEQPFIKIN
CGAIPENLLESELFGHEPGSFTGASKNGKPGKFEIANGGTLLLDEIGELSKDLQVKLLRALQDQEITRIGGVKPRQLDVK
IIACTNRDLEEMVSQGEFREDLYYRLSVVPLYIPPLRERPDDIPFLIRHYIRKYNEKYGVNKGLSSSALEELVSYNWPGN
VRELENMIERLVIMVPENLIETSDLPQQIKESNVKILENLSLPDAVSKLEKRMLQKAMEQSNNTREAAQILGVAQSTVVR
KLDKYGLNYKHDDQAN

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=343, Percent_Identity=42.2740524781341, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI87082117, Length=333, Percent_Identity=43.8438438438438, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1789233, Length=319, Percent_Identity=43.2601880877743, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI1790437, Length=303, Percent_Identity=44.2244224422442, Blast_Score=267, Evalue=1e-72,
Organism=Escherichia coli, GI1789087, Length=363, Percent_Identity=40.771349862259, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1788905, Length=381, Percent_Identity=39.3700787401575, Blast_Score=249, Evalue=4e-67,
Organism=Escherichia coli, GI1790299, Length=349, Percent_Identity=38.3954154727794, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1786524, Length=356, Percent_Identity=39.0449438202247, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI87082152, Length=216, Percent_Identity=52.7777777777778, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI1787583, Length=384, Percent_Identity=34.8958333333333, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI87081872, Length=307, Percent_Identity=40.3908794788274, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI87081858, Length=479, Percent_Identity=27.348643006263, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI1789828, Length=303, Percent_Identity=29.3729372937294, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 64904; Mature: 64773

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLQNSDLEIILDSVYNGIIAINKEGEINLFNKSASEILGMSKEEVLGCDIREIIPETG
CCCCCCCCHHHHHHHHHCCEEEECCCCCEEEECCCHHHHHCCCHHHHHCCCHHHHCCCCH
LFKVLESSQTFTTEKFVVNKKTLLTNRSPIFKEGELIGALGIFQDISELEHISQELAKTK
HHHHHHCCCCEEHHHHEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AINDELRAIIESSYDGFWITDGEGYTIMINSSYERISGAKAEEVVGRHMKELEEEGFCSE
HHHHHHHHHHHCCCCCEEEECCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHCCCCCC
SVTLKVLEQKERVTLMHELFSGKKVMVTGNPVFDSDGNITKVVTNVRDISELLELKDELE
CHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
KTQALTRHYKEKLTEMEEKLGEGEIVAKSKVKKRLLAQAARVAAFDSTVLITGETGVGKE
HHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHH
IVAKYIHQNSNRSEQPFIKINCGAIPENLLESELFGHEPGSFTGASKNGKPGKFEIANGG
HHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCC
TLLLDEIGELSKDLQVKLLRALQDQEITRIGGVKPRQLDVKIIACTNRDLEEMVSQGEFR
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHCCCHH
EDLYYRLSVVPLYIPPLRERPDDIPFLIRHYIRKYNEKYGVNKGLSSSALEELVSYNWPG
HHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
NVRELENMIERLVIMVPENLIETSDLPQQIKESNVKILENLSLPDAVSKLEKRMLQKAME
CHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHH
QSNNTREAAQILGVAQSTVVRKLDKYGLNYKHDDQAN
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TNLQNSDLEIILDSVYNGIIAINKEGEINLFNKSASEILGMSKEEVLGCDIREIIPETG
CCCCCCCHHHHHHHHHCCEEEECCCCCEEEECCCHHHHHCCCHHHHHCCCHHHHCCCCH
LFKVLESSQTFTTEKFVVNKKTLLTNRSPIFKEGELIGALGIFQDISELEHISQELAKTK
HHHHHHCCCCEEHHHHEECCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AINDELRAIIESSYDGFWITDGEGYTIMINSSYERISGAKAEEVVGRHMKELEEEGFCSE
HHHHHHHHHHHCCCCCEEEECCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHCCCCCC
SVTLKVLEQKERVTLMHELFSGKKVMVTGNPVFDSDGNITKVVTNVRDISELLELKDELE
CHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
KTQALTRHYKEKLTEMEEKLGEGEIVAKSKVKKRLLAQAARVAAFDSTVLITGETGVGKE
HHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHH
IVAKYIHQNSNRSEQPFIKINCGAIPENLLESELFGHEPGSFTGASKNGKPGKFEIANGG
HHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCC
TLLLDEIGELSKDLQVKLLRALQDQEITRIGGVKPRQLDVKIIACTNRDLEEMVSQGEFR
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHCCCHH
EDLYYRLSVVPLYIPPLRERPDDIPFLIRHYIRKYNEKYGVNKGLSSSALEELVSYNWPG
HHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
NVRELENMIERLVIMVPENLIETSDLPQQIKESNVKILENLSLPDAVSKLEKRMLQKAME
CHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHH
QSNNTREAAQILGVAQSTVVRKLDKYGLNYKHDDQAN
HCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]