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The map label for this gene is polX [H]

Identifier: 188586429

GI number: 188586429

Start: 1886501

End: 1888216

Strand: Reverse

Name: polX [H]

Synonym: Nther_1814

Alternate gene names: 188586429

Gene position: 1888216-1886501 (Counterclockwise)

Preceding gene: 188586430

Following gene: 188586428

Centisome position: 59.65

GC content: 34.79

Gene sequence:

>1716_bases
ATGACTAATACGGAAATATCTTTAATATTAAAGGAAATAGCTGAAATATTAGAACTTAAAGGCGAAAATTTTTATAAGAT
AAGGGCTTATAGAAGGGGGGCAAGAAATGTTGAAACCCTTTCAGAAGATATGACTAGGCTAGTCCAAGAAAATCGTCTTA
GACAGATATCAGGTATTGGTAAGGGAATTGCTTCACAAATAGAAGAGATTGTTAGGACGGGTAGATCTTCATTATTAGAA
GAGCTGCGAAGCGAAGTGCCAACAGGACTGAGAAGAATTTTGGGGATTCCTGGTGTAGGTGTTAAATCTGCTCAAAAACT
ATACTATCAATTGGGAATAAGCTCGTTAAATCAGCTCAAAGAGGCTTGTGAACAGGATCAAATCAAAGAATTACCAGGGT
TTGGAGAAAAAATTCAAGAGAAGATTTTACAGGGGATTTCCAAAGTTGAAAGTTCTGAACGCGAAACTTTATTGGGAATA
GCTCTGCCCATGAATGAGAATATTATCGCGACTTTGGAAAAGTTCCCTGAAATTGAAAATGTGGAAACCTCGGGTAGTGT
TAGAAGGAGAAAGGGAATGGTTCAAGATATTGACCTTGTAGTTAAAACACAAGAACCGAAAACAGTAAAGGAAAAAATTA
TCGATTTACCGGCTGTTTATCAGGTTTTAGAAGAACAAAAAAATGTTCTAAGTGTTTTAAATACAGTTGGTATAAGAATA
GATTTTTATTTAACCAGTGAAAAAAACTTTTATTACTATCTATTTTTGGCTACTGGTAGTGAGGACCATATTGAAGAAGT
AGCGAATCTAGCTTTTCAGAAAGGTTATGAATTAAAAAAAGCGGGTTTAATTGATAAAGAAACAGAACAAGGAGTAGAAT
TATATTCCGAATTTGACTTGTATAATAAGCTGGATTTACCATATATAGCGCCTGAACTTAGAGAAAATCGTGGTGAAGTA
GAAAAGGCTCATAAAGACAAATTACCTTCATTAATTAATGTCAAAGATATTAAAGGTGATCTTCACATTCATACTAACTG
GACCGATGGTGCAGGAGACTTACAAGATATGGTTGATGGAGCTAAAAATATGGGTTATGAATATATTGCTATTACTGACC
ATTCTAAATCTTTAAAAATTGCCAATGGGCTATCAGAGTTTCAGCTTGAAAGACAGGTGGAGGAGATCCAAAAACTTAAT
CACGAATTAAAAGACTTTACTATATTCACTGGTACAGAAGTTGATATTTTGAAAAACGGCGAACTGGATTTTTCTTCAGA
TATATTACGTGAATTAGATTTTGTGATTGCTTCTATCCATCAAGGATTTAATGATCCTGGAGATGTGATTACGAACAGGA
TTTGTAAAGCCATGGAAAACCCTTATGTAAAAGCTATCGCTCATCCTACGGGTAGATTACTGGGAAAACGACAAGGTCAT
GACTTAGATTTTGAACGCCTTTTCGATACTGCGGTAGCTACTAATACCGCTTTAGAAATTAACTCCTCAATTGACAGATT
AGATTTACCAGAGGAATTAGTTCTCCAAGGAATTAATAAAGGGGTTAAGTTTTTAATTAGTACAGATGCCCACAGTACTG
AATCTTTTAAAGATATCCAATATGGTGTTTTTATTGCTAGACGAGGTTGGCTCTCTAAGGAACAAGTGATCAATACTTAC
GGACTAGCAGAATTTACGGAAAGTTTTTTAGGTTAA

Upstream 100 bases:

>100_bases
CTTTAAACTTAGCCGATGAATACTTAAAGCTTGAAGACGAACATACCGATCTATTGGAAATGTTAGACGAGAAGGGTGAA
ACTGATAAGGGTGATAATTG

Downstream 100 bases:

>100_bases
GCTGTATTAAAGTTGTACGTTGATAGCTGAAGAGCTCAACTATCAACAACGGAGTATAACAGCACCTAGCTTAATTATAA
TAGTAAATGTTAAACTATCC

Product: PHP domain protein

Products: NA

Alternate protein names: DNA polymerase type-X; 3'-5' exodeoxyribonuclease; 3'-5' exonuclease [H]

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MTNTEISLILKEIAEILELKGENFYKIRAYRRGARNVETLSEDMTRLVQENRLRQISGIGKGIASQIEEIVRTGRSSLLE
ELRSEVPTGLRRILGIPGVGVKSAQKLYYQLGISSLNQLKEACEQDQIKELPGFGEKIQEKILQGISKVESSERETLLGI
ALPMNENIIATLEKFPEIENVETSGSVRRRKGMVQDIDLVVKTQEPKTVKEKIIDLPAVYQVLEEQKNVLSVLNTVGIRI
DFYLTSEKNFYYYLFLATGSEDHIEEVANLAFQKGYELKKAGLIDKETEQGVELYSEFDLYNKLDLPYIAPELRENRGEV
EKAHKDKLPSLINVKDIKGDLHIHTNWTDGAGDLQDMVDGAKNMGYEYIAITDHSKSLKIANGLSEFQLERQVEEIQKLN
HELKDFTIFTGTEVDILKNGELDFSSDILRELDFVIASIHQGFNDPGDVITNRICKAMENPYVKAIAHPTGRLLGKRQGH
DLDFERLFDTAVATNTALEINSSIDRLDLPEELVLQGINKGVKFLISTDAHSTESFKDIQYGVFIARRGWLSKEQVINTY
GLAEFTESFLG

Sequences:

>Translated_571_residues
MTNTEISLILKEIAEILELKGENFYKIRAYRRGARNVETLSEDMTRLVQENRLRQISGIGKGIASQIEEIVRTGRSSLLE
ELRSEVPTGLRRILGIPGVGVKSAQKLYYQLGISSLNQLKEACEQDQIKELPGFGEKIQEKILQGISKVESSERETLLGI
ALPMNENIIATLEKFPEIENVETSGSVRRRKGMVQDIDLVVKTQEPKTVKEKIIDLPAVYQVLEEQKNVLSVLNTVGIRI
DFYLTSEKNFYYYLFLATGSEDHIEEVANLAFQKGYELKKAGLIDKETEQGVELYSEFDLYNKLDLPYIAPELRENRGEV
EKAHKDKLPSLINVKDIKGDLHIHTNWTDGAGDLQDMVDGAKNMGYEYIAITDHSKSLKIANGLSEFQLERQVEEIQKLN
HELKDFTIFTGTEVDILKNGELDFSSDILRELDFVIASIHQGFNDPGDVITNRICKAMENPYVKAIAHPTGRLLGKRQGH
DLDFERLFDTAVATNTALEINSSIDRLDLPEELVLQGINKGVKFLISTDAHSTESFKDIQYGVFIARRGWLSKEQVINTY
GLAEFTESFLG
>Mature_570_residues
TNTEISLILKEIAEILELKGENFYKIRAYRRGARNVETLSEDMTRLVQENRLRQISGIGKGIASQIEEIVRTGRSSLLEE
LRSEVPTGLRRILGIPGVGVKSAQKLYYQLGISSLNQLKEACEQDQIKELPGFGEKIQEKILQGISKVESSERETLLGIA
LPMNENIIATLEKFPEIENVETSGSVRRRKGMVQDIDLVVKTQEPKTVKEKIIDLPAVYQVLEEQKNVLSVLNTVGIRID
FYLTSEKNFYYYLFLATGSEDHIEEVANLAFQKGYELKKAGLIDKETEQGVELYSEFDLYNKLDLPYIAPELRENRGEVE
KAHKDKLPSLINVKDIKGDLHIHTNWTDGAGDLQDMVDGAKNMGYEYIAITDHSKSLKIANGLSEFQLERQVEEIQKLNH
ELKDFTIFTGTEVDILKNGELDFSSDILRELDFVIASIHQGFNDPGDVITNRICKAMENPYVKAIAHPTGRLLGKRQGHD
LDFERLFDTAVATNTALEINSSIDRLDLPEELVLQGINKGVKFLISTDAHSTESFKDIQYGVFIARRGWLSKEQVINTYG
LAEFTESFLG

Specific function: Strictly DNA-template-directed DNA polymerase, preferentially acting on DNA structures containing gaps from one to a few nucleotides and bearing a phosphate group at the 5' end of the downstream DNA. The fact that PolX is able to conduct filling of a sing

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the PHP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002054
- InterPro:   IPR010996
- InterPro:   IPR003583
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR022311 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 64523; Mature: 64392

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTEISLILKEIAEILELKGENFYKIRAYRRGARNVETLSEDMTRLVQENRLRQISGIG
CCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KGIASQIEEIVRTGRSSLLEELRSEVPTGLRRILGIPGVGVKSAQKLYYQLGISSLNQLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
EACEQDQIKELPGFGEKIQEKILQGISKVESSERETLLGIALPMNENIIATLEKFPEIEN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCCCCCC
VETSGSVRRRKGMVQDIDLVVKTQEPKTVKEKIIDLPAVYQVLEEQKNVLSVLNTVGIRI
CCCCCHHHHHCCCHHCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCEEE
DFYLTSEKNFYYYLFLATGSEDHIEEVANLAFQKGYELKKAGLIDKETEQGVELYSEFDL
EEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHH
YNKLDLPYIAPELRENRGEVEKAHKDKLPSLINVKDIKGDLHIHTNWTDGAGDLQDMVDG
HHCCCCCCCCHHHHHCCCHHHHHHHHCCCCCCCCEECCCCEEEEECCCCCCCHHHHHHHH
AKNMGYEYIAITDHSKSLKIANGLSEFQLERQVEEIQKLNHELKDFTIFTGTEVDILKNG
HHHCCEEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCEEEEEECC
ELDFSSDILRELDFVIASIHQGFNDPGDVITNRICKAMENPYVKAIAHPTGRLLGKRQGH
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEECCCCHHHHHCCCCCC
DLDFERLFDTAVATNTALEINSSIDRLDLPEELVLQGINKGVKFLISTDAHSTESFKDIQ
CCCHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
YGVFIARRGWLSKEQVINTYGLAEFTESFLG
HHEEEECCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNTEISLILKEIAEILELKGENFYKIRAYRRGARNVETLSEDMTRLVQENRLRQISGIG
CCCHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KGIASQIEEIVRTGRSSLLEELRSEVPTGLRRILGIPGVGVKSAQKLYYQLGISSLNQLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
EACEQDQIKELPGFGEKIQEKILQGISKVESSERETLLGIALPMNENIIATLEKFPEIEN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHCCCCCC
VETSGSVRRRKGMVQDIDLVVKTQEPKTVKEKIIDLPAVYQVLEEQKNVLSVLNTVGIRI
CCCCCHHHHHCCCHHCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCEEE
DFYLTSEKNFYYYLFLATGSEDHIEEVANLAFQKGYELKKAGLIDKETEQGVELYSEFDL
EEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHH
YNKLDLPYIAPELRENRGEVEKAHKDKLPSLINVKDIKGDLHIHTNWTDGAGDLQDMVDG
HHCCCCCCCCHHHHHCCCHHHHHHHHCCCCCCCCEECCCCEEEEECCCCCCCHHHHHHHH
AKNMGYEYIAITDHSKSLKIANGLSEFQLERQVEEIQKLNHELKDFTIFTGTEVDILKNG
HHHCCEEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCEEEEECCEEEEEECC
ELDFSSDILRELDFVIASIHQGFNDPGDVITNRICKAMENPYVKAIAHPTGRLLGKRQGH
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEECCCCHHHHHCCCCCC
DLDFERLFDTAVATNTALEINSSIDRLDLPEELVLQGINKGVKFLISTDAHSTESFKDIQ
CCCHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHHH
YGVFIARRGWLSKEQVINTYGLAEFTESFLG
HHEEEECCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]