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The map label for this gene is bcrB [H]

Identifier: 188586386

GI number: 188586386

Start: 1837538

End: 1838797

Strand: Reverse

Name: bcrB [H]

Synonym: Nther_1771

Alternate gene names: 188586386

Gene position: 1838797-1837538 (Counterclockwise)

Preceding gene: 188586387

Following gene: 188586385

Centisome position: 58.09

GC content: 35.87

Gene sequence:

>1260_bases
TTGGATCCCGTTAAAATTTTTAAGGAAAAAATAGGTGGTAATTTTAGTAGAAAAGCACTTAAGTCACCTCAAGCTTATAG
ACTTGCCAAATTAATGTTTGTGGCAAGAAACCCCTATCCCTTCCGCGGGATTAAAGAACTTACTGCCCTTGGTCTAGATC
AGACGGCCAAGGCTTATGATGACGAACAAAAAGTAGCTTTTACTACAGCTTTTTTTCCTGAAGAAATAGTGCATGCCCTA
GGTTGTGTTCCTTTTGCACCAGAAGTTGCTGCAGCTACAGCAACTTCTTTAAATCTCTCACAAGAACTCCTTAAAAACTC
CGAAAAAGAAGGTATGTCACGTGATGCCTGTTCTTTTCATAGAGTGGCTGCCGCAGGGGGGCCAAGAGATTATTTTCCAA
TACCTGATTTTTTCTTGGCCAGTTCTCACTTATGTGATGGTGCTCCTCAATTATTTAGATACTTATCTCAAAAATATGAC
CGCCCATATTATTTTTTAGATGTACCAGCTCAGAAAGATGCACAAGCTGTAGAATATGTAGCACAACAATTAGAAGAATT
AATAAAAGAAGTTACTAAAAATTTAAATATTTCCTTGGATGAAGAAAGGCTTAAAGAGGTAATTGAGAACTCCAACAGAG
CACGGGAGGCTCAATTATACTTAAATAATATCAGAAAGAAGTATCCTGGTATTTTACCTGGGGCCCAAGCTATAAATTTA
GTGTATTTACATTTCCTTTGTCAAGGTCTTGAAAAAACTCCCGACATTTATAATATACTTGCGGAGGAAATAGAAAATAA
AGCTTCAAAAAACGAACATAAAACTGATGCTCCCCGTATTCTGTGGTCTCATTTACGTCCTTTTTACGAGAATGATATTT
TTACAATCTTAGAACAAGAACTGGAAGTTAATATTGTTTTTGAAGAGATGAATCAAGTTTATTGGCCTCCTCTAGACCCA
GCAAAACCTTATGAAAGTTTAGCTCGCAAGATAATTAATAATCCACTTGTAGGTCCTTTAGACTATCGAATGGATTATTT
AAAACAAATTATTGATGATTATTCTGTTGATGGGATTATTCATTTCTCACATTGGGGATGTAGACATGCAGTTGGGGCTG
TACCTTTACTTAAACAAAAAGCTAAGGATTTAAATGTAGCTTTCTTAAATTTAGATGCAGACTGTGTTGATCGGCAAAAT
TACTTTTCGGGTCAGGTGAGGACTAGACTTGAAAGTTTCATTGAAATGCTATCATTTTAA

Upstream 100 bases:

>100_bases
TCGTGACTTTAGTCATGAGAGGTTCACTTAGATTGAATAACTTGTTTAAGATTTAGATATCTAATGATAGTAAAAATTGA
TAGGGAATGGAGGGATAATT

Downstream 100 bases:

>100_bases
TCTATTGACACTGTTGTATTTCGTTTTTGGTAATTATAATTTTCAATGTATGATTAGGCGAGCTTAGCATTTTAATAATA
TTTCTTAAGACAGGCACGAA

Product: 2-hydroxyglutaryl-CoA dehydratase D-component

Products: NA

Alternate protein names: 3-hydroxybenzoyl-CoA reductase subunit beta [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MDPVKIFKEKIGGNFSRKALKSPQAYRLAKLMFVARNPYPFRGIKELTALGLDQTAKAYDDEQKVAFTTAFFPEEIVHAL
GCVPFAPEVAAATATSLNLSQELLKNSEKEGMSRDACSFHRVAAAGGPRDYFPIPDFFLASSHLCDGAPQLFRYLSQKYD
RPYYFLDVPAQKDAQAVEYVAQQLEELIKEVTKNLNISLDEERLKEVIENSNRAREAQLYLNNIRKKYPGILPGAQAINL
VYLHFLCQGLEKTPDIYNILAEEIENKASKNEHKTDAPRILWSHLRPFYENDIFTILEQELEVNIVFEEMNQVYWPPLDP
AKPYESLARKIINNPLVGPLDYRMDYLKQIIDDYSVDGIIHFSHWGCRHAVGAVPLLKQKAKDLNVAFLNLDADCVDRQN
YFSGQVRTRLESFIEMLSF

Sequences:

>Translated_419_residues
MDPVKIFKEKIGGNFSRKALKSPQAYRLAKLMFVARNPYPFRGIKELTALGLDQTAKAYDDEQKVAFTTAFFPEEIVHAL
GCVPFAPEVAAATATSLNLSQELLKNSEKEGMSRDACSFHRVAAAGGPRDYFPIPDFFLASSHLCDGAPQLFRYLSQKYD
RPYYFLDVPAQKDAQAVEYVAQQLEELIKEVTKNLNISLDEERLKEVIENSNRAREAQLYLNNIRKKYPGILPGAQAINL
VYLHFLCQGLEKTPDIYNILAEEIENKASKNEHKTDAPRILWSHLRPFYENDIFTILEQELEVNIVFEEMNQVYWPPLDP
AKPYESLARKIINNPLVGPLDYRMDYLKQIIDDYSVDGIIHFSHWGCRHAVGAVPLLKQKAKDLNVAFLNLDADCVDRQN
YFSGQVRTRLESFIEMLSF
>Mature_419_residues
MDPVKIFKEKIGGNFSRKALKSPQAYRLAKLMFVARNPYPFRGIKELTALGLDQTAKAYDDEQKVAFTTAFFPEEIVHAL
GCVPFAPEVAAATATSLNLSQELLKNSEKEGMSRDACSFHRVAAAGGPRDYFPIPDFFLASSHLCDGAPQLFRYLSQKYD
RPYYFLDVPAQKDAQAVEYVAQQLEELIKEVTKNLNISLDEERLKEVIENSNRAREAQLYLNNIRKKYPGILPGAQAINL
VYLHFLCQGLEKTPDIYNILAEEIENKASKNEHKTDAPRILWSHLRPFYENDIFTILEQELEVNIVFEEMNQVYWPPLDP
AKPYESLARKIINNPLVGPLDYRMDYLKQIIDDYSVDGIIHFSHWGCRHAVGAVPLLKQKAKDLNVAFLNLDADCVDRQN
YFSGQVRTRLESFIEMLSF

Specific function: Catalyzes the anaerobic reduction of benzoyl-CoA and 3- hydroxybenzoyl-CoA to form cyclohexa-1,5-diene-1-carbonyl-CoA and 3-hydroxycyclohexa-1,5-diene-1-carbonyl-CoA, respectively. The enzyme also reduces other benzoyl-CoA analogs with small substituents

COG id: COG1775

COG function: function code E; Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011955
- InterPro:   IPR010327 [H]

Pfam domain/function: PF06050 HGD-D [H]

EC number: =1.3.99.15 [H]

Molecular weight: Translated: 47913; Mature: 47913

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPVKIFKEKIGGNFSRKALKSPQAYRLAKLMFVARNPYPFRGIKELTALGLDQTAKAYD
CCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHCC
DEQKVAFTTAFFPEEIVHALGCVPFAPEVAAATATSLNLSQELLKNSEKEGMSRDACSFH
CCCCEEEEHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHH
RVAAAGGPRDYFPIPDFFLASSHLCDGAPQLFRYLSQKYDRPYYFLDVPAQKDAQAVEYV
HHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
AQQLEELIKEVTKNLNISLDEERLKEVIENSNRAREAQLYLNNIRKKYPGILPGAQAINL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VYLHFLCQGLEKTPDIYNILAEEIENKASKNEHKTDAPRILWSHLRPFYENDIFTILEQE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCHHHHHHHHH
LEVNIVFEEMNQVYWPPLDPAKPYESLARKIINNPLVGPLDYRMDYLKQIIDDYSVDGII
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEE
HFSHWGCRHAVGAVPLLKQKAKDLNVAFLNLDADCVDRQNYFSGQVRTRLESFIEMLSF
EECCCCHHHHHCCHHHHHHHCCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDPVKIFKEKIGGNFSRKALKSPQAYRLAKLMFVARNPYPFRGIKELTALGLDQTAKAYD
CCHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHCC
DEQKVAFTTAFFPEEIVHALGCVPFAPEVAAATATSLNLSQELLKNSEKEGMSRDACSFH
CCCCEEEEHHHCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHH
RVAAAGGPRDYFPIPDFFLASSHLCDGAPQLFRYLSQKYDRPYYFLDVPAQKDAQAVEYV
HHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
AQQLEELIKEVTKNLNISLDEERLKEVIENSNRAREAQLYLNNIRKKYPGILPGAQAINL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
VYLHFLCQGLEKTPDIYNILAEEIENKASKNEHKTDAPRILWSHLRPFYENDIFTILEQE
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCHHHHHHHHH
LEVNIVFEEMNQVYWPPLDPAKPYESLARKIINNPLVGPLDYRMDYLKQIIDDYSVDGII
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEE
HFSHWGCRHAVGAVPLLKQKAKDLNVAFLNLDADCVDRQNYFSGQVRTRLESFIEMLSF
EECCCCHHHHHCCHHHHHHHCCCCCEEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9746358; 11208796 [H]