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The map label for this gene is efp

Identifier: 188586334

GI number: 188586334

Start: 1787210

End: 1787776

Strand: Reverse

Name: efp

Synonym: Nther_1717

Alternate gene names: 188586334

Gene position: 1787776-1787210 (Counterclockwise)

Preceding gene: 188586335

Following gene: 188586333

Centisome position: 56.48

GC content: 34.92

Gene sequence:

>567_bases
ATGATTACTAGTAATGATTTTAAAAATGGCATGACAATAGAAGTTGATGGAGAAGTATACAGTATTGTGGAATTTCAACA
TGTTAAGCCTGGTAAAGGTGCAGCATTTGTTCGTACGAAACTAAGGCATATGAAATCAGGAAATGTATCTGAAAAAACTT
TTCGCGCTGGTGAAAAAGTAAAACGTGCTCATTTAGAAGAACGCGAAATGCAATTTCTGTACGCGGCAGGAGATATGTAT
AACTTTATGGATACAGAGTCCTTTGAGCAGTATACTTTAACCAAAGATCAGTTAGAAGATAAAACACAGTTTATAAAAGA
AAACATGATAATTACTGTATTGTTTCATAATGGAGAAGAAATAAGTATTGAACTGCCGGTATTCGTCGAACTGGCAGTGA
GCGAAACTGAACCGGGAGTAAAAGGAGATACAGCTTCAGGAGGTAGTAAACCAGCAACTTTAGAAACTGGTGCAACTGTT
AATGTACCTTTCTTTATTAATGAAGGTGATATAATCAAAGTTGATACTAGAACTAGTGAATATATTGAAAGGGTAAAAGG
GGAATAA

Upstream 100 bases:

>100_bases
GAACAAGGCTGTGAAGTTCTAACACGATCAACTAAGGATTTAATCGAGATTTAATTATAGTAGTACCCGTGGAACTAAAG
TTGACAAAGGAGGTATTGTA

Downstream 100 bases:

>100_bases
TAATATGCGACACTAAATATATTTTTTGAGGAGGTATACAATGCAGTACAGAGTTTCCTACCTTAAAGGCATGATGGATG
GAATGAATATGGTAAGTAAC

Product: translation elongation factor P (EF-P)

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MITSNDFKNGMTIEVDGEVYSIVEFQHVKPGKGAAFVRTKLRHMKSGNVSEKTFRAGEKVKRAHLEEREMQFLYAAGDMY
NFMDTESFEQYTLTKDQLEDKTQFIKENMIITVLFHNGEEISIELPVFVELAVSETEPGVKGDTASGGSKPATLETGATV
NVPFFINEGDIIKVDTRTSEYIERVKGE

Sequences:

>Translated_188_residues
MITSNDFKNGMTIEVDGEVYSIVEFQHVKPGKGAAFVRTKLRHMKSGNVSEKTFRAGEKVKRAHLEEREMQFLYAAGDMY
NFMDTESFEQYTLTKDQLEDKTQFIKENMIITVLFHNGEEISIELPVFVELAVSETEPGVKGDTASGGSKPATLETGATV
NVPFFINEGDIIKVDTRTSEYIERVKGE
>Mature_188_residues
MITSNDFKNGMTIEVDGEVYSIVEFQHVKPGKGAAFVRTKLRHMKSGNVSEKTFRAGEKVKRAHLEEREMQFLYAAGDMY
NFMDTESFEQYTLTKDQLEDKTQFIKENMIITVLFHNGEEISIELPVFVELAVSETEPGVKGDTASGGSKPATLETGATV
NVPFFINEGDIIKVDTRTSEYIERVKGE

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=183, Percent_Identity=44.2622950819672, Blast_Score=173, Evalue=8e-45,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=32.9787234042553, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_NATTJ (B2A549)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001917879.1
- ProteinModelPortal:   B2A549
- SMR:   B2A549
- GeneID:   6316885
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_1717
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21145; Mature: 21145

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITSNDFKNGMTIEVDGEVYSIVEFQHVKPGKGAAFVRTKLRHMKSGNVSEKTFRAGEKV
CCCCCCCCCCCEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
KRAHLEEREMQFLYAAGDMYNFMDTESFEQYTLTKDQLEDKTQFIKENMIITVLFHNGEE
HHHHHHHHHEEEEEECCCCCCCCCCCCCHHEECCHHHHHHHHHHHHCCEEEEEEEECCCE
ISIELPVFVELAVSETEPGVKGDTASGGSKPATLETGATVNVPFFINEGDIIKVDTRTSE
EEEECCEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCEEEEECCHHH
YIERVKGE
HHHHHCCC
>Mature Secondary Structure
MITSNDFKNGMTIEVDGEVYSIVEFQHVKPGKGAAFVRTKLRHMKSGNVSEKTFRAGEKV
CCCCCCCCCCCEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHH
KRAHLEEREMQFLYAAGDMYNFMDTESFEQYTLTKDQLEDKTQFIKENMIITVLFHNGEE
HHHHHHHHHEEEEEECCCCCCCCCCCCCHHEECCHHHHHHHHHHHHCCEEEEEEEECCCE
ISIELPVFVELAVSETEPGVKGDTASGGSKPATLETGATVNVPFFINEGDIIKVDTRTSE
EEEECCEEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCEEEEECCHHH
YIERVKGE
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA