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The map label for this gene is yafV [C]

Identifier: 188586226

GI number: 188586226

Start: 1687272

End: 1688075

Strand: Reverse

Name: yafV [C]

Synonym: Nther_1609

Alternate gene names: 188586226

Gene position: 1688075-1687272 (Counterclockwise)

Preceding gene: 188586227

Following gene: 188586224

Centisome position: 53.33

GC content: 39.43

Gene sequence:

>804_bases
ATGTTCCAAGTAGCTGCTATTCAAATGACTCCCATTATGAATGATGTAGACGGAAATATAAAAAGAGGAGTACATTTGGC
AAAAAATGCGATTGCAGAGGAAGCTGATTTAATCGTATTTCCAGAACTATGGACTACTGGATATCATCTTTCGAGAGAAT
CATTTCGTGCCTTGGCCGAAAAACCTGATGGTAAAACAGTATCAACTTTTCAAGAAATCGCCAAGCAGGGAGAAGTATCA
ATAGTATGTCCCTTCGTTGAGGAAGCAGGGGATAAAATTTATATAGCTGCTGCTGTAATAGATACAGAAGGGGAAACTAG
AGGAATAGTCCGTAAAAGTTTACTTTGGGGAAGAGAACAACAAATATTTAATGCTGGTGTAATGGAGTATCCGACTTTCG
ACTCCAAAGTTGGCAAAATAGGTATCCTAATCTGTTATGAAATGGAATTCCCTGAAACAAGTCGTTTATTAGCACTAGAA
GGGGCTGAAGTAATAGTTTGTCCGTCAGTATGGAGTATGTCTGCTGCCCATAGATGGGAAATTCAACTACCGGCAAGGGC
TCTAGATAATACAGTTTTTGTCCTGGGTGTTAATACAGTAGGAAACAATAGCTGTGGTAAAAGTAAATTATTAAGCCCAA
TGGGAGATGTTTTGGCAGAAGCTTCCGGCAGAAAAGAAGAAATTTTAATAAGGGCTATCGACAAAGAAGCACTACTATGG
GCGAGAGACGAAGTTTCTTATTTAGAAGATTACAAAACAAAGCTAACTCCCGGAGGAGAGGAAATACCCACTCCGATATG
GTAG

Upstream 100 bases:

>100_bases
CCAGCCAACTAGGCTATGAATTTAGAGATTAACTCCTTTAAGAATCTAAGAGACTATGATACCATTGATGAGAGTATTGG
GGTTCAAGGAGGTGCATAAT

Downstream 100 bases:

>100_bases
CTTATACTTTTCAAAAAAGAAAAGTATTATATTAAAAAACCGCTGGTTAGAAACCAGCGGTTTTTTATGGTTGTTGTATG
GTCGGAGCGGCGAGATTTGA

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MFQVAAIQMTPIMNDVDGNIKRGVHLAKNAIAEEADLIVFPELWTTGYHLSRESFRALAEKPDGKTVSTFQEIAKQGEVS
IVCPFVEEAGDKIYIAAAVIDTEGETRGIVRKSLLWGREQQIFNAGVMEYPTFDSKVGKIGILICYEMEFPETSRLLALE
GAEVIVCPSVWSMSAAHRWEIQLPARALDNTVFVLGVNTVGNNSCGKSKLLSPMGDVLAEASGRKEEILIRAIDKEALLW
ARDEVSYLEDYKTKLTPGGEEIPTPIW

Sequences:

>Translated_267_residues
MFQVAAIQMTPIMNDVDGNIKRGVHLAKNAIAEEADLIVFPELWTTGYHLSRESFRALAEKPDGKTVSTFQEIAKQGEVS
IVCPFVEEAGDKIYIAAAVIDTEGETRGIVRKSLLWGREQQIFNAGVMEYPTFDSKVGKIGILICYEMEFPETSRLLALE
GAEVIVCPSVWSMSAAHRWEIQLPARALDNTVFVLGVNTVGNNSCGKSKLLSPMGDVLAEASGRKEEILIRAIDKEALLW
ARDEVSYLEDYKTKLTPGGEEIPTPIW
>Mature_267_residues
MFQVAAIQMTPIMNDVDGNIKRGVHLAKNAIAEEADLIVFPELWTTGYHLSRESFRALAEKPDGKTVSTFQEIAKQGEVS
IVCPFVEEAGDKIYIAAAVIDTEGETRGIVRKSLLWGREQQIFNAGVMEYPTFDSKVGKIGILICYEMEFPETSRLLALE
GAEVIVCPSVWSMSAAHRWEIQLPARALDNTVFVLGVNTVGNNSCGKSKLLSPMGDVLAEASGRKEEILIRAIDKEALLW
ARDEVSYLEDYKTKLTPGGEEIPTPIW

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=271, Percent_Identity=26.5682656826568, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI5031947, Length=273, Percent_Identity=27.1062271062271, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI297632350, Length=273, Percent_Identity=27.1062271062271, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI297632348, Length=273, Percent_Identity=27.1062271062271, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI7706509, Length=181, Percent_Identity=29.8342541436464, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=241, Percent_Identity=26.1410788381743, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17533173, Length=303, Percent_Identity=27.0627062706271, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323383, Length=267, Percent_Identity=28.0898876404494, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17933642, Length=243, Percent_Identity=30.0411522633745, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21355835, Length=264, Percent_Identity=27.6515151515151, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21358471, Length=189, Percent_Identity=26.984126984127, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29521; Mature: 29521

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQVAAIQMTPIMNDVDGNIKRGVHLAKNAIAEEADLIVFPELWTTGYHLSRESFRALAE
CEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHCCCEEECHHHHHHHHC
KPDGKTVSTFQEIAKQGEVSIVCPFVEEAGDKIYIAAAVIDTEGETRGIVRKSLLWGREQ
CCCCCHHHHHHHHHHCCCEEEEEEEHHHCCCEEEEEEEEEECCCCHHHHHHHHHHCCCHH
QIFNAGVMEYPTFDSKVGKIGILICYEMEFPETSRLLALEGAEVIVCPSVWSMSAAHRWE
HHHHCCCEECCCCCCCCCEEEEEEEEEECCCCCCCEEEECCCCEEECCCCCCCCCCEEEE
IQLPARALDNTVFVLGVNTVGNNSCGKSKLLSPMGDVLAEASGRKEEILIRAIDKEALLW
EEECHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHEEE
ARDEVSYLEDYKTKLTPGGEEIPTPIW
ECHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFQVAAIQMTPIMNDVDGNIKRGVHLAKNAIAEEADLIVFPELWTTGYHLSRESFRALAE
CEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHCCCEEECHHHHHHHHC
KPDGKTVSTFQEIAKQGEVSIVCPFVEEAGDKIYIAAAVIDTEGETRGIVRKSLLWGREQ
CCCCCHHHHHHHHHHCCCEEEEEEEHHHCCCEEEEEEEEEECCCCHHHHHHHHHHCCCHH
QIFNAGVMEYPTFDSKVGKIGILICYEMEFPETSRLLALEGAEVIVCPSVWSMSAAHRWE
HHHHCCCEECCCCCCCCCEEEEEEEEEECCCCCCCEEEECCCCEEECCCCCCCCCCEEEE
IQLPARALDNTVFVLGVNTVGNNSCGKSKLLSPMGDVLAEASGRKEEILIRAIDKEALLW
EEECHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHEEE
ARDEVSYLEDYKTKLTPGGEEIPTPIW
ECHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8526497 [H]