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The map label for this gene is prmA [H]

Identifier: 188585811

GI number: 188585811

Start: 1257435

End: 1258409

Strand: Direct

Name: prmA [H]

Synonym: Nther_1185

Alternate gene names: 188585811

Gene position: 1257435-1258409 (Clockwise)

Preceding gene: 188585810

Following gene: 188585812

Centisome position: 39.72

GC content: 37.44

Gene sequence:

>975_bases
ATGAATGATTCCAAAATAATGAAAAGGGGCGAGAACATGAAGTGGGCCGAATTGACACTCACCACAGAGAGGGAAGCCAT
GGAAGCTGTTTCTAATTTATTTCACGAATCGGGAGCAGGTGGAGTTGTAATTAAAGATCCCAAAATAGTACCCCAATTAG
ATGAAGATGAGTTATGGCAAGACCCACAAAAGTTAGAAAAACATGCGGAACACAGTTTGATTGACAGAGTATATGTTATG
GCATATTTACCCTGGGATGAAGAACTATCTAACAAACTAAGTACTATTAGAGAAAGAATCAGTGACATGGAGAATTATGG
TTTGAATGTCTCTGCTAATGATCTCAATGTTAGTAAAGTAGATGAAGACGATTGGTCGGAAGCGTGGAAAGAGTACTATC
AACCTGTAAACGTTAATGGAATTACTGTCCGGCCCACTTGGACTTCCCCGGATAATAATGAGCAAACTACAATTTGGTTG
GATCCAGGAATGGCTTTTGGGACGGGAACTCATCCCACTACTATTATGTGTATTTCCTTTTTAAAACAATATCTACAGGG
AAATGAAAAAGTTATTGACTTAGGATGTGGTTCAGGGATTCTGTCAATAGCTGCTGCTAAGTTAGGAGTTGAAAAAGTTT
TTGCTTATGATATTGATTCGGTAGCCTGTAGGGTAGCTGGTCAAAATGCTAACTTGAATGAAGTTAGAGATTTAATAGAC
ATTAAACGGGGAGATGTTAAAAAACAAGTAGTTGAAGAAAAGGCAGATGTAGTTGTCGGTAATTTGATTTCGGATATAAT
TATTTCTTTAGTACCAAATATAAAATATATGATGAAGGAAAATGCAATTTTCATTGGATCGGGTATTGCTGTAAACAAAA
AAGAAGCTGTTATTGATGAATTTAATAGTCATGGTATGGAAATTGTTGCAGAGGAAACCTCAGGGGAGTGGATAGCCCTG
GTGGTTCGCAATTAG

Upstream 100 bases:

>100_bases
AAGCAAAAACAACTTGTCAGAGAGTTGGCCTTATCTATGGGGAAAAACATCTCATCTGACGAAAGTTTTTTAAACAGGGT
TAAAAAAGCCCTGGGAGGAA

Downstream 100 bases:

>100_bases
TGGTCAAATACCAAGAATTTTTTTAGAAGAAAATTCATTAACTGAAGTTAGTGCAGGCCAGAAAATAACAGGTTCCCGAG
AAGATTACCACTATTTGACA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MNDSKIMKRGENMKWAELTLTTEREAMEAVSNLFHESGAGGVVIKDPKIVPQLDEDELWQDPQKLEKHAEHSLIDRVYVM
AYLPWDEELSNKLSTIRERISDMENYGLNVSANDLNVSKVDEDDWSEAWKEYYQPVNVNGITVRPTWTSPDNNEQTTIWL
DPGMAFGTGTHPTTIMCISFLKQYLQGNEKVIDLGCGSGILSIAAAKLGVEKVFAYDIDSVACRVAGQNANLNEVRDLID
IKRGDVKKQVVEEKADVVVGNLISDIIISLVPNIKYMMKENAIFIGSGIAVNKKEAVIDEFNSHGMEIVAEETSGEWIAL
VVRN

Sequences:

>Translated_324_residues
MNDSKIMKRGENMKWAELTLTTEREAMEAVSNLFHESGAGGVVIKDPKIVPQLDEDELWQDPQKLEKHAEHSLIDRVYVM
AYLPWDEELSNKLSTIRERISDMENYGLNVSANDLNVSKVDEDDWSEAWKEYYQPVNVNGITVRPTWTSPDNNEQTTIWL
DPGMAFGTGTHPTTIMCISFLKQYLQGNEKVIDLGCGSGILSIAAAKLGVEKVFAYDIDSVACRVAGQNANLNEVRDLID
IKRGDVKKQVVEEKADVVVGNLISDIIISLVPNIKYMMKENAIFIGSGIAVNKKEAVIDEFNSHGMEIVAEETSGEWIAL
VVRN
>Mature_324_residues
MNDSKIMKRGENMKWAELTLTTEREAMEAVSNLFHESGAGGVVIKDPKIVPQLDEDELWQDPQKLEKHAEHSLIDRVYVM
AYLPWDEELSNKLSTIRERISDMENYGLNVSANDLNVSKVDEDDWSEAWKEYYQPVNVNGITVRPTWTSPDNNEQTTIWL
DPGMAFGTGTHPTTIMCISFLKQYLQGNEKVIDLGCGSGILSIAAAKLGVEKVFAYDIDSVACRVAGQNANLNEVRDLID
IKRGDVKKQVVEEKADVVVGNLISDIIISLVPNIKYMMKENAIFIGSGIAVNKKEAVIDEFNSHGMEIVAEETSGEWIAL
VVRN

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=317, Percent_Identity=29.3375394321767, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 36222; Mature: 36222

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSKIMKRGENMKWAELTLTTEREAMEAVSNLFHESGAGGVVIKDPKIVPQLDEDELWQ
CCCHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHC
DPQKLEKHAEHSLIDRVYVMAYLPWDEELSNKLSTIRERISDMENYGLNVSANDLNVSKV
CHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
DEDDWSEAWKEYYQPVNVNGITVRPTWTSPDNNEQTTIWLDPGMAFGTGTHPTTIMCISF
CCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHH
LKQYLQGNEKVIDLGCGSGILSIAAAKLGVEKVFAYDIDSVACRVAGQNANLNEVRDLID
HHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHHH
IKRGDVKKQVVEEKADVVVGNLISDIIISLVPNIKYMMKENAIFIGSGIAVNKKEAVIDE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEECCEEECCHHHHHHH
FNSHGMEIVAEETSGEWIALVVRN
HCCCCEEEEEECCCCCEEEEEEEC
>Mature Secondary Structure
MNDSKIMKRGENMKWAELTLTTEREAMEAVSNLFHESGAGGVVIKDPKIVPQLDEDELWQ
CCCHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHC
DPQKLEKHAEHSLIDRVYVMAYLPWDEELSNKLSTIRERISDMENYGLNVSANDLNVSKV
CHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCC
DEDDWSEAWKEYYQPVNVNGITVRPTWTSPDNNEQTTIWLDPGMAFGTGTHPTTIMCISF
CCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHH
LKQYLQGNEKVIDLGCGSGILSIAAAKLGVEKVFAYDIDSVACRVAGQNANLNEVRDLID
HHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCHHHHHHHHH
IKRGDVKKQVVEEKADVVVGNLISDIIISLVPNIKYMMKENAIFIGSGIAVNKKEAVIDE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCEEEEECCEEECCHHHHHHH
FNSHGMEIVAEETSGEWIALVVRN
HCCCCEEEEEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA