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The map label for this gene is fur [H]

Identifier: 188585764

GI number: 188585764

Start: 1204779

End: 1205210

Strand: Direct

Name: fur [H]

Synonym: Nther_1138

Alternate gene names: 188585764

Gene position: 1204779-1205210 (Clockwise)

Preceding gene: 188585763

Following gene: 188585768

Centisome position: 38.06

GC content: 26.85

Gene sequence:

>432_bases
ATGGATTACGAGTTAGATTTAGCAGAAATAGAAAAAAAGTTTTATAATTATAAATTCACACCTCAAAGAAAAACTATTCT
CAAGGTTTTATTTGAAAATAAAGGACATCACTTAAGTGCAGAAGAAATTTTACAGCTATCCAAAGAAAAAAATTCAGACA
TTGGATTTGCTACAGTTTATAGAACTTTGGATTTATTTGAGGAACTTGAAATTGTACATAAGTTACATTTTGGTGATGGA
TGTAGTAGATACGAATTAACTCGTACCGGATCTAGCCATCACCATCATTTGATTTGCCTAAATTGTAATCAAATTTTTGA
AGTTAAAGATGACTTACTAAAAAAATTAGAAAATAATATTGAGACTCAGCATAATTTTAAAATTTCAGACCATAGATTAC
ACTTTTATGGTTATTGTAAAAATTGTAAATAA

Upstream 100 bases:

>100_bases
GAAATATCGGACTGGGACTAGCACTAGCACCTCCCATTAAGTTATTGACATATGTTAATAAATAAACTAGAATTGACATT
AGGAAAGGCAGGGATCTTTA

Downstream 100 bases:

>100_bases
ATTAAATAACACTTATCAGGGTGAATTAACCAATTAATAATCACCAGTGTCGTTTATTAATTGATTTTTTTCGTTGAAAA
AGGTTTTGTAACCCAGTTGG

Product: ferric uptake regulator, Fur family

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MDYELDLAEIEKKFYNYKFTPQRKTILKVLFENKGHHLSAEEILQLSKEKNSDIGFATVYRTLDLFEELEIVHKLHFGDG
CSRYELTRTGSSHHHHLICLNCNQIFEVKDDLLKKLENNIETQHNFKISDHRLHFYGYCKNCK

Sequences:

>Translated_143_residues
MDYELDLAEIEKKFYNYKFTPQRKTILKVLFENKGHHLSAEEILQLSKEKNSDIGFATVYRTLDLFEELEIVHKLHFGDG
CSRYELTRTGSSHHHHLICLNCNQIFEVKDDLLKKLENNIETQHNFKISDHRLHFYGYCKNCK
>Mature_143_residues
MDYELDLAEIEKKFYNYKFTPQRKTILKVLFENKGHHLSAEEILQLSKEKNSDIGFATVYRTLDLFEELEIVHKLHFGDG
CSRYELTRTGSSHHHHLICLNCNQIFEVKDDLLKKLENNIETQHNFKISDHRLHFYGYCKNCK

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=127, Percent_Identity=38.5826771653543, Blast_Score=93, Evalue=5e-21,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17034; Mature: 17034

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYELDLAEIEKKFYNYKFTPQRKTILKVLFENKGHHLSAEEILQLSKEKNSDIGFATVY
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHCCCCCCCHHHHH
RTLDLFEELEIVHKLHFGDGCSRYELTRTGSSHHHHLICLNCNQIFEVKDDLLKKLENNI
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCC
ETQHNFKISDHRLHFYGYCKNCK
CCCCCCEECCCEEEEEEEECCCC
>Mature Secondary Structure
MDYELDLAEIEKKFYNYKFTPQRKTILKVLFENKGHHLSAEEILQLSKEKNSDIGFATVY
CCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHCCCCCCCHHHHH
RTLDLFEELEIVHKLHFGDGCSRYELTRTGSSHHHHLICLNCNQIFEVKDDLLKKLENNI
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCC
ETQHNFKISDHRLHFYGYCKNCK
CCCCCCEECCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]