Click here to switch to the map view.

The map label for this gene is stc [H]

Identifier: 188584732

GI number: 188584732

Start: 106768

End: 108393

Strand: Direct

Name: stc [H]

Synonym: Nther_0090

Alternate gene names: 188584732

Gene position: 106768-108393 (Clockwise)

Preceding gene: 188584731

Following gene: 188584733

Centisome position: 3.37

GC content: 35.67

Gene sequence:

>1626_bases
ATGAGTTTTTTCAGATATCAAGTTCAGACTGTTGATAGAGTTGGAATGGTTCTCGATGTTTTAAGAGTTGTATACTTAAA
AAATATTAATATAACTGCTATGGAAGTGGCACCGCAGTTAATCTATTTGAAACTTGATTTTGCGCCTGCTATGAAAGGGG
CCTTAGAAAGCGCAGTCAAAGAAATTCCTGGTGTTAGAGGGATTGATGAAATTAGTCTGTTGCCTCAAGAAGAAAAAGAA
CAAAAACTCAGAGGTATTTTAGATACTATAGGAGAAGGAATAATTGCATTAGACAAATCTGGAATAATTACTATGATTAA
TCCCTCGGCAGAAAAGATTTTAAATCTATCAGAAAACATTGAGGGTCGAGACATTCGAGATATACTTTCTGCTGAATTAC
CCATATTAAAAACTTTGTCTGCCGGGGAGGATTATGACAATAAGGAAATTTTTGTCACACTACCTGGTGGTAAAAGCCAT
TATTTGACTTCAGGGAGACCTATCAAAAACGATGATGGCAATACTGTAGGAGCTGTAGCTGCCATCAAAGATATAAATGA
AGTGCGTAAATTAGTTCATCGGATTACTCACCCGACCATGCTATCTTTTGACGATATAATAGCTGAAAGTAGTATTATGA
ATGAAACAATTTCGTTTGCAAAAAAAATTGCTCATGGAGACTCTACCGTTCTGTTAACTGGGGAAAGCGGCACAGGAAAA
GAATTGTTCGCCAGAGCTATTCATATGGAAAGTCCTAGGAAGGATTGTCCCTTTGTCCCTCTTAACTGTGCTGCCATACC
GGAAACACTGATGGAAAGTGAATTATTTGGATATGAAGAAGGTGCTTTTACGGGTGCGAAAAAAGGTGGAAAACATGGAC
TGTTTGAGCTAGCTAACAAAGGTACAGTATTCTTAGATGAAATAGGTAATCTCAATCCACAATTACAAGTCAAATTACTC
AGAGTTTTACAAGAAAGAGAAGTCCGCAGAATAGGTGGAAAAGAGGAAATTAGTGTCGATATAAGGGTAATCACTGCAAC
AAACCATAACTTAGAAAAGCTTGTTAATGAAGGTTATTTTAGAGAAGACCTGTATTATCGCTTAAATGTTATACCTATAA
AACTGCCACCATTAAGAAATAGAAAAGAGGATATTATTCCTTTAGCAAACCATATACTCGGGCAAATGAGGACTAATCAT
GGAGGACAGTATCAACTTTCCCCAAAAAGTCGAGAACTGCTAAAAACTTACTCTTGGCCCGGCAATGTAAGAGAACTCGA
AAATATAATTGAGCGTGCAGTTAATTTGGCTAATGACAATATAATTGAAGGTGAACATTTATTTTTTGGTCAAGAGGATG
GTTTTTCAAATTACGAAGGCGAAATGGAAAACTGGGAACAGAATCAACAGTATCAAAATGGTCAGAGCGAAGCAGAAATC
AGTGTAAATTATAAAGACAAAGACTTTTCTCAAATATTACAGTCAGTTGAAAAACAAATATTGCAAAAAGTTTTGAGTGA
ACATGCAAGTGCCAGAAAAGCTGCTAAACAATTAGGAGTTTCCCATACTACAATTTTAAATAAAATTAAAAAATATGGGC
TGCAAATTAATCAAGAATCAAACTGA

Upstream 100 bases:

>100_bases
TTTTCTTGGTATTCAGGGGGATGATAGGGAGGAACTATCCATTGGGGATAGAAGTTTATTAAAACACCGAACTAGCAATA
GTTAATGATGGGGTGATTTA

Downstream 100 bases:

>100_bases
GATAATTGTTCGACAGAATAATGCTTTTTTGAAAGGGGTATAATCTTGAAAATTTCACAAATAAAGAAGATACTTCAAGC
CGATATATTAACTGGAAAAG

Product: PAS modulated sigma54 specific transcriptional regulator, Fis family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MSFFRYQVQTVDRVGMVLDVLRVVYLKNINITAMEVAPQLIYLKLDFAPAMKGALESAVKEIPGVRGIDEISLLPQEEKE
QKLRGILDTIGEGIIALDKSGIITMINPSAEKILNLSENIEGRDIRDILSAELPILKTLSAGEDYDNKEIFVTLPGGKSH
YLTSGRPIKNDDGNTVGAVAAIKDINEVRKLVHRITHPTMLSFDDIIAESSIMNETISFAKKIAHGDSTVLLTGESGTGK
ELFARAIHMESPRKDCPFVPLNCAAIPETLMESELFGYEEGAFTGAKKGGKHGLFELANKGTVFLDEIGNLNPQLQVKLL
RVLQEREVRRIGGKEEISVDIRVITATNHNLEKLVNEGYFREDLYYRLNVIPIKLPPLRNRKEDIIPLANHILGQMRTNH
GGQYQLSPKSRELLKTYSWPGNVRELENIIERAVNLANDNIIEGEHLFFGQEDGFSNYEGEMENWEQNQQYQNGQSEAEI
SVNYKDKDFSQILQSVEKQILQKVLSEHASARKAAKQLGVSHTTILNKIKKYGLQINQESN

Sequences:

>Translated_541_residues
MSFFRYQVQTVDRVGMVLDVLRVVYLKNINITAMEVAPQLIYLKLDFAPAMKGALESAVKEIPGVRGIDEISLLPQEEKE
QKLRGILDTIGEGIIALDKSGIITMINPSAEKILNLSENIEGRDIRDILSAELPILKTLSAGEDYDNKEIFVTLPGGKSH
YLTSGRPIKNDDGNTVGAVAAIKDINEVRKLVHRITHPTMLSFDDIIAESSIMNETISFAKKIAHGDSTVLLTGESGTGK
ELFARAIHMESPRKDCPFVPLNCAAIPETLMESELFGYEEGAFTGAKKGGKHGLFELANKGTVFLDEIGNLNPQLQVKLL
RVLQEREVRRIGGKEEISVDIRVITATNHNLEKLVNEGYFREDLYYRLNVIPIKLPPLRNRKEDIIPLANHILGQMRTNH
GGQYQLSPKSRELLKTYSWPGNVRELENIIERAVNLANDNIIEGEHLFFGQEDGFSNYEGEMENWEQNQQYQNGQSEAEI
SVNYKDKDFSQILQSVEKQILQKVLSEHASARKAAKQLGVSHTTILNKIKKYGLQINQESN
>Mature_540_residues
SFFRYQVQTVDRVGMVLDVLRVVYLKNINITAMEVAPQLIYLKLDFAPAMKGALESAVKEIPGVRGIDEISLLPQEEKEQ
KLRGILDTIGEGIIALDKSGIITMINPSAEKILNLSENIEGRDIRDILSAELPILKTLSAGEDYDNKEIFVTLPGGKSHY
LTSGRPIKNDDGNTVGAVAAIKDINEVRKLVHRITHPTMLSFDDIIAESSIMNETISFAKKIAHGDSTVLLTGESGTGKE
LFARAIHMESPRKDCPFVPLNCAAIPETLMESELFGYEEGAFTGAKKGGKHGLFELANKGTVFLDEIGNLNPQLQVKLLR
VLQEREVRRIGGKEEISVDIRVITATNHNLEKLVNEGYFREDLYYRLNVIPIKLPPLRNRKEDIIPLANHILGQMRTNHG
GQYQLSPKSRELLKTYSWPGNVRELENIIERAVNLANDNIIEGEHLFFGQEDGFSNYEGEMENWEQNQQYQNGQSEAEIS
VNYKDKDFSQILQSVEKQILQKVLSEHASARKAAKQLGVSHTTILNKIKKYGLQINQESN

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3283

COG function: function code KE; Transcriptional regulator of aromatic amino acids metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=350, Percent_Identity=44.2857142857143, Blast_Score=275, Evalue=6e-75,
Organism=Escherichia coli, GI1787583, Length=545, Percent_Identity=31.743119266055, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1789233, Length=464, Percent_Identity=37.2844827586207, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI87082117, Length=347, Percent_Identity=43.8040345821326, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1790437, Length=328, Percent_Identity=43.9024390243902, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1788905, Length=238, Percent_Identity=50.4201680672269, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1789087, Length=339, Percent_Identity=42.7728613569322, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1790299, Length=377, Percent_Identity=39.2572944297082, Blast_Score=231, Evalue=7e-62,
Organism=Escherichia coli, GI87082152, Length=234, Percent_Identity=50.8547008547009, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI1786524, Length=241, Percent_Identity=46.8879668049792, Blast_Score=226, Evalue=4e-60,
Organism=Escherichia coli, GI87081872, Length=236, Percent_Identity=44.9152542372881, Blast_Score=196, Evalue=4e-51,
Organism=Escherichia coli, GI87081858, Length=472, Percent_Identity=25, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789828, Length=299, Percent_Identity=31.1036789297659, Blast_Score=133, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 60633; Mature: 60502

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFRYQVQTVDRVGMVLDVLRVVYLKNINITAMEVAPQLIYLKLDFAPAMKGALESAVK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEECCHHHHHHHHHHHH
EIPGVRGIDEISLLPQEEKEQKLRGILDTIGEGIIALDKSGIITMINPSAEKILNLSENI
HCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCHHHHHHHHCCC
EGRDIRDILSAELPILKTLSAGEDYDNKEIFVTLPGGKSHYLTSGRPIKNDDGNTVGAVA
CCCHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEECCCCCCEECCCCCCCCCCCCCHHHHH
AIKDINEVRKLVHRITHPTMLSFDDIIAESSIMNETISFAKKIAHGDSTVLLTGESGTGK
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCH
ELFARAIHMESPRKDCPFVPLNCAAIPETLMESELFGYEEGAFTGAKKGGKHGLFELANK
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCC
GTVFLDEIGNLNPQLQVKLLRVLQEREVRRIGGKEEISVDIRVITATNHNLEKLVNEGYF
CCEEEEHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHCCCC
REDLYYRLNVIPIKLPPLRNRKEDIIPLANHILGQMRTNHGGQYQLSPKSRELLKTYSWP
HHCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCC
GNVRELENIIERAVNLANDNIIEGEHLFFGQEDGFSNYEGEMENWEQNQQYQNGQSEAEI
CCHHHHHHHHHHHHHHCCCCEECCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEE
SVNYKDKDFSQILQSVEKQILQKVLSEHASARKAAKQLGVSHTTILNKIKKYGLQINQES
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
N
C
>Mature Secondary Structure 
SFFRYQVQTVDRVGMVLDVLRVVYLKNINITAMEVAPQLIYLKLDFAPAMKGALESAVK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEEECCHHHHHHHHHHHH
EIPGVRGIDEISLLPQEEKEQKLRGILDTIGEGIIALDKSGIITMINPSAEKILNLSENI
HCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCHHHHHHHHCCC
EGRDIRDILSAELPILKTLSAGEDYDNKEIFVTLPGGKSHYLTSGRPIKNDDGNTVGAVA
CCCHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEECCCCCCEECCCCCCCCCCCCCHHHHH
AIKDINEVRKLVHRITHPTMLSFDDIIAESSIMNETISFAKKIAHGDSTVLLTGESGTGK
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCH
ELFARAIHMESPRKDCPFVPLNCAAIPETLMESELFGYEEGAFTGAKKGGKHGLFELANK
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCC
GTVFLDEIGNLNPQLQVKLLRVLQEREVRRIGGKEEISVDIRVITATNHNLEKLVNEGYF
CCEEEEHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCHHHHHHCCCC
REDLYYRLNVIPIKLPPLRNRKEDIIPLANHILGQMRTNHGGQYQLSPKSRELLKTYSWP
HHCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHCCCC
GNVRELENIIERAVNLANDNIIEGEHLFFGQEDGFSNYEGEMENWEQNQQYQNGQSEAEI
CCHHHHHHHHHHHHHHCCCCEECCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEE
SVNYKDKDFSQILQSVEKQILQKVLSEHASARKAAKQLGVSHTTILNKIKKYGLQINQES
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA