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The map label for this gene is xerD [H]

Identifier: 188527478

GI number: 188527478

Start: 667093

End: 668163

Strand: Reverse

Name: xerD [H]

Synonym: HPSH_03490

Alternate gene names: 188527478

Gene position: 668163-667093 (Counterclockwise)

Preceding gene: 188527479

Following gene: 188527471

Centisome position: 41.54

GC content: 38.75

Gene sequence:

>1071_bases
ATGAAGCACCCCTTAGAAGAATTAAAAGACCCTATAGAAAATCTTTTGCTATGGATTGGGCGCTTTTTGCGTTACAAATG
CACAAGCCTGTCTAATTCCCAAGTGAAAGACCAAAACAAGATTTTTGAATGCTTGAACGAACTAAATCAAGCGTTCGTCA
GCTCAAGCCACTTAGAAAAAGTTTGTAAAAAAGCCCGTAACGCCGGATTACTCGGTATCAACACCTACGCATTACCCCTA
CTCAAATTCCACGAATACACAAAAAAGATTTCTTTAAAATCGCTCAAAAGCATTGATGAAGTGCTGCTCGCTGAATTTTT
GAGCGTTTATACCGGGGGTTTGAGTTTAGCCACTAAGAAAAATTACAGGATCGCCCTACTTGGGCTTTTTAGCTACATAG
ACAAGCAAAATCAAGATGAAAATGAAAAATCTTATATTTACAATATCACGCTTAAAAATATCAGCGGAGTCAATCAAAGC
GCGGGCAACAAGCTCCCTACTCATTTAAATAATGAAGAATTAGAAAAATTTTTAGAGGGCATTGATAAAATAGAAATGTC
TGCTAAAGTGCGCGCCAGAAACCGCCTGCTCATTAAAATCATCGTTTTTACGGGCATGCGTTCTAACGAAGCCTTACAGC
TTAAAATAAAGGATTTTACTTTAGAAAATGGCTGTTACACGATTTTGATTAAAGGTAAGGGCGACAAATACAGAGCGGTG
ATGCTCAAAGCTTTCCACATTGAGAGCCTTTTAAAAGAATGGCTCATGGAAAGGGAATTATATCCCGTTAAAAATGATTT
ATTGTTTTGCAACCAAAAAGGCAGCGCTTTAACGCAAGCGTATTTGTATAAACAGGTGGAGCGCATCATCAATTTTGCAG
GTTTAAGAAGGGAAAAAAACGGGGCGCACATGTTAAGGCATTCTTTTGCGACCTTGCTTTATCAAAAACGCCATGATTTG
ATTTTAGTTCAAGAAGCTCTAGGGCATGCGAGCTTGAATACCAGCAGGATTTACACGCATTTTGACAAGCAGCGTTTAGA
AGAAGCGGCGAGCATTTGGGAAGAAAATTAA

Upstream 100 bases:

>100_bases
AATGGAAAACGCAGATAATGGGAATGAGTGTTTTATGCCTGTTCCCATTCTATTTTTTGAAAACAAACAAGAGCTTTATA
ACTCTATTAACTAACCCCCA

Downstream 100 bases:

>100_bases
AACCACCCCCCTACTCCCTTAAAAAAATGATTTTTACCATAAAATAATCAAAGCCCCATTTTTTAAGAAATTAAAAAGTT
TTTAGCTTGCTGGTTTAAAA

Product: integrase-recombinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKHPLEELKDPIENLLLWIGRFLRYKCTSLSNSQVKDQNKIFECLNELNQAFVSSSHLEKVCKKARNAGLLGINTYALPL
LKFHEYTKKISLKSLKSIDEVLLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGVNQS
AGNKLPTHLNNEELEKFLEGIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAV
MLKAFHIESLLKEWLMERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDL
ILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEEN

Sequences:

>Translated_356_residues
MKHPLEELKDPIENLLLWIGRFLRYKCTSLSNSQVKDQNKIFECLNELNQAFVSSSHLEKVCKKARNAGLLGINTYALPL
LKFHEYTKKISLKSLKSIDEVLLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGVNQS
AGNKLPTHLNNEELEKFLEGIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAV
MLKAFHIESLLKEWLMERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDL
ILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEEN
>Mature_356_residues
MKHPLEELKDPIENLLLWIGRFLRYKCTSLSNSQVKDQNKIFECLNELNQAFVSSSHLEKVCKKARNAGLLGINTYALPL
LKFHEYTKKISLKSLKSIDEVLLAEFLSVYTGGLSLATKKNYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGVNQS
AGNKLPTHLNNEELEKFLEGIDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAV
MLKAFHIESLLKEWLMERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKNGAHMLRHSFATLLYQKRHDL
ILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEEN

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerC binding sites by a short central region, forming

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=273, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790244, Length=273, Percent_Identity=27.1062271062271, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790767, Length=196, Percent_Identity=29.0816326530612, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 41124; Mature: 41124

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHPLEELKDPIENLLLWIGRFLRYKCTSLSNSQVKDQNKIFECLNELNQAFVSSSHLEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VCKKARNAGLLGINTYALPLLKFHEYTKKISLKSLKSIDEVLLAEFLSVYTGGLSLATKK
HHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
NYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGVNQSAGNKLPTHLNNEELEKFLEG
CCEEHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
IDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAV
HHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEEEEEEECCCEEEEEEECCCCCCHHH
MLKAFHIESLLKEWLMERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKN
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEEN
HHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKHPLEELKDPIENLLLWIGRFLRYKCTSLSNSQVKDQNKIFECLNELNQAFVSSSHLEK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VCKKARNAGLLGINTYALPLLKFHEYTKKISLKSLKSIDEVLLAEFLSVYTGGLSLATKK
HHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
NYRIALLGLFSYIDKQNQDENEKSYIYNITLKNISGVNQSAGNKLPTHLNNEELEKFLEG
CCEEHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
IDKIEMSAKVRARNRLLIKIIVFTGMRSNEALQLKIKDFTLENGCYTILIKGKGDKYRAV
HHHHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEEEEEEECCCEEEEEEECCCCCCHHH
MLKAFHIESLLKEWLMERELYPVKNDLLFCNQKGSALTQAYLYKQVERIINFAGLRREKN
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
GAHMLRHSFATLLYQKRHDLILVQEALGHASLNTSRIYTHFDKQRLEEAASIWEEN
HHHHHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]