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The map label for this gene is czcN [H]

Identifier: 187928850

GI number: 187928850

Start: 1865522

End: 1866376

Strand: Reverse

Name: czcN [H]

Synonym: Rpic_1767

Alternate gene names: 187928850

Gene position: 1866376-1865522 (Counterclockwise)

Preceding gene: 187928853

Following gene: 187928849

Centisome position: 47.34

GC content: 58.6

Gene sequence:

>855_bases
ATGTCGCAGAAGATGACTGTCAGATTGCCGAGCTATGACACAACCGGATTCGCTGGCCCGGGGGCAAGATTAACAACGTA
TTACATTTCGGCAATAAAGCCTGACAACGGAAGGGCAACCTTAGAATGCCGGCCATTAGTGCTCGTTTTCGCGCCAGTGT
GTCCACTCGAAGTGCGCGACATTCTCCTCCAGCCCCCGAACCGCATGACCGATTCTTCAATCTCCCCGTCCCAACCCGCT
GGTCTCTCGAGGGCGCTGGACAATTTCCTGACACGCCACCGCATCGGCGTTTGGCGTGTTGTCGTAACGTTTGTCCTGGC
AAGTCTGGTCTTTGGCCATTCTCGCTGGGACGGTACCTGGGTGTCGCCGCTGCTGCTGACGCTGGGGATGTTGGGGGTGA
GCCTGGCCACGGTCGGGCGGCTCTGGTGCGCGTTGTACATTTCCGGGCGCAAGAACAATACCTTGGTGACCTCGGGTCCA
TATTCACTGTGTCGCCATCCGCTCTATGTCTGCAACTTGCTAGGCATTATCGGACTAGGGGCGATGACCGAGTCGCTGGC
GGTTACCGCAGTCCTGGCGCTCGCATTTGCGCTGATGTACCCGGCTGTCATCCGGACGGAAGACCGCTTTCTGGCTTCCG
CCTTCCCGGAATTCGCCGAATACGCACGCCGTACACCAGCGTTCTTTCCCCGTCTGTCGCTGTATAGGGGGGAGTCGACA
TGGACGGTCCATGTGTCTTCCTTTCAACGCAATATTGCGGACTCGGTCTGGTTTCTCGGCCTGTCGGTGGTCGTGGAGTC
GTTTGATTTGTTCCATGACGCCGGCGTCCTCCGGGCGGTCGTGACGCTTGCCTGA

Upstream 100 bases:

>100_bases
CAGCATTAGCGAGATCGGAGAATTCCGAGCTCAATGTGCGGATGATGTCGTTCATTGCGGAGCGTCTCTGGGTGTGTCCT
GAAAATGGCCAAGACAGTCT

Downstream 100 bases:

>100_bases
TGCGGGCAACTCCGCATACACGTACAGCCATGCACTACGCTCACGTCTCCGATTCTGTTGTCGAGAGCATGCTCGTGATG
CTGGTCGGCCTGATCGTCCT

Product: Isoprenylcysteine carboxyl methyltransferase

Products: NA

Alternate protein names: Cation efflux system protein CzcN [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSQKMTVRLPSYDTTGFAGPGARLTTYYISAIKPDNGRATLECRPLVLVFAPVCPLEVRDILLQPPNRMTDSSISPSQPA
GLSRALDNFLTRHRIGVWRVVVTFVLASLVFGHSRWDGTWVSPLLLTLGMLGVSLATVGRLWCALYISGRKNNTLVTSGP
YSLCRHPLYVCNLLGIIGLGAMTESLAVTAVLALAFALMYPAVIRTEDRFLASAFPEFAEYARRTPAFFPRLSLYRGEST
WTVHVSSFQRNIADSVWFLGLSVVVESFDLFHDAGVLRAVVTLA

Sequences:

>Translated_284_residues
MSQKMTVRLPSYDTTGFAGPGARLTTYYISAIKPDNGRATLECRPLVLVFAPVCPLEVRDILLQPPNRMTDSSISPSQPA
GLSRALDNFLTRHRIGVWRVVVTFVLASLVFGHSRWDGTWVSPLLLTLGMLGVSLATVGRLWCALYISGRKNNTLVTSGP
YSLCRHPLYVCNLLGIIGLGAMTESLAVTAVLALAFALMYPAVIRTEDRFLASAFPEFAEYARRTPAFFPRLSLYRGEST
WTVHVSSFQRNIADSVWFLGLSVVVESFDLFHDAGVLRAVVTLA
>Mature_283_residues
SQKMTVRLPSYDTTGFAGPGARLTTYYISAIKPDNGRATLECRPLVLVFAPVCPLEVRDILLQPPNRMTDSSISPSQPAG
LSRALDNFLTRHRIGVWRVVVTFVLASLVFGHSRWDGTWVSPLLLTLGMLGVSLATVGRLWCALYISGRKNNTLVTSGPY
SLCRHPLYVCNLLGIIGLGAMTESLAVTAVLALAFALMYPAVIRTEDRFLASAFPEFAEYARRTPAFFPRLSLYRGESTW
TVHVSSFQRNIADSVWFLGLSVVVESFDLFHDAGVLRAVVTLA

Specific function: Component of the CZC cation-efflux system that confers resistance to cobalt, zinc and cadmium [H]

COG id: COG2020

COG function: function code O; Putative protein-S-isoprenylcysteine methyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To A.xylosoxydans nccN [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007269 [H]

Pfam domain/function: PF04140 ICMT [H]

EC number: NA

Molecular weight: Translated: 31233; Mature: 31102

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKMTVRLPSYDTTGFAGPGARLTTYYISAIKPDNGRATLECRPLVLVFAPVCPLEVRD
CCCCEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEECCEEEEECCCCCHHHHH
ILLQPPNRMTDSSISPSQPAGLSRALDNFLTRHRIGVWRVVVTFVLASLVFGHSRWDGTW
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
VSPLLLTLGMLGVSLATVGRLWCALYISGRKNNTLVTSGPYSLCRHPLYVCNLLGIIGLG
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
AMTESLAVTAVLALAFALMYPAVIRTEDRFLASAFPEFAEYARRTPAFFPRLSLYRGEST
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCE
WTVHVSSFQRNIADSVWFLGLSVVVESFDLFHDAGVLRAVVTLA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQKMTVRLPSYDTTGFAGPGARLTTYYISAIKPDNGRATLECRPLVLVFAPVCPLEVRD
CCCEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCEEEEECCEEEEECCCCCHHHHH
ILLQPPNRMTDSSISPSQPAGLSRALDNFLTRHRIGVWRVVVTFVLASLVFGHSRWDGTW
HHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
VSPLLLTLGMLGVSLATVGRLWCALYISGRKNNTLVTSGPYSLCRHPLYVCNLLGIIGLG
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
AMTESLAVTAVLALAFALMYPAVIRTEDRFLASAFPEFAEYARRTPAFFPRLSLYRGEST
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCE
WTVHVSSFQRNIADSVWFLGLSVVVESFDLFHDAGVLRAVVTLA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9044283; 7766206 [H]