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The map label for this gene is czcC [H]

Identifier: 187928847

GI number: 187928847

Start: 1863528

End: 1864784

Strand: Reverse

Name: czcC [H]

Synonym: Rpic_1764

Alternate gene names: 187928847

Gene position: 1864784-1863528 (Counterclockwise)

Preceding gene: 187928849

Following gene: 187928846

Centisome position: 47.3

GC content: 61.34

Gene sequence:

>1257_bases
ATGCGAAGACTATTTCTGCCGCTCGGGCTGGCGGTAGCATTTCTCAGCCCAAACTTTGCCGTAGCGCAATCTGACACCGG
CACGTCCATGGTGCCCGTCTTCCCAAGGGAAGCGGCGGGACCGTTGACCCTCGAGGCCGCGTTGTCGCTGGCGGCAGGAA
GCAATTTCAACCTGTCCGCCGCCGCCAAGGAACTCGATTCCACAGAAGGTGGGATCATGCAGGCCCGGGTTATTCCGAAC
CCGGAACTCCAGACGCTGGTCGAGGACACGCGGAAATCCACCCGTACATCCACCGCCCAGATGAATATCCCCATCGAACT
GGGCGGCAAGCGCTCGGCTCGTATCAATGCCGCGGAAAGGACGCGCGAACTGGCGCAGGCAACGCTGGCTGGCGTTCGCG
GTGACATTCGGGCGCAGGTAATCGAGAGCTTTTTTTCCGTCTTGATCGCACAGGAACGCGTCAAGCTGGCAACTGGCTCC
GCGGATATCGCTGCGAGGGGCGCGCAAGCCGCTTCACGCCGCGTCGCGGCCGGCAAGATCTCCCCGGTTGACGAAACTAA
GGCACGTGTCGAACAGGCCAACGCCGAACTTGAATTGGCCGAAGCAACGGCGAGCCTGCAGTCCGCCCGTCAGGCGTTGA
CGGCGTTGTGGGGCAATGCATCGCCGCAGTTTACCGAAGCACAGGGCAATCTGGACGCGCTGCCATCCAGGCCGGCGCCT
GAACTCCTTCTGAAGGAGCTGGAAAACTCACCGCTGGTGGCCGCAAGCCGCGCTGAACTTGACCGCCGCCAGGCATTGGT
GGGCGTTGAGCGCAGCCGCCAGTATCCGGATCTGACAGTCAGTCTGGGTGCCAAGCGAGATACAGAAGCCAACCGCAACA
TGGCGGTGATCGGTGTGGCGATCCCGTTGCCGATTTTTGACCGGAATCAGGGCAACTTGTATTCGGCCATTCGCCAGGCG
GACAAGGCCCAGGATGAATATCTGGCCAATCGCATCAGCCTGACCCGAAATCTCCTGATGGCATCGAACCAGCTGTCGGT
ATCGCGCGCCTCGGCACAAACGCTGAAGCAGACCGTCTTGCCAGGCGCCGAGCAAGCCTTCAACGCGGCGACCATTGGCT
TCGAGGCCGGCAAGTTCAATTATCTGGACGTCCTGGATGCCCAGCGCACGCTGTTCCAGGCACGCATCCGCTATCTCGGC
GTGCTTGGACAAACCTATCAGGCGGCGACCACGATCGATCGCATTCTGGGACGTTAA

Upstream 100 bases:

>100_bases
TCCTCAGTGGCAGCGTCTCGCTTGATCGGCGAGACGACGACTCTTTTTCTCCTTTCGTCTCTCGCCGAATTCTCCTGGTC
ACATACCTTGGTGCAATTCG

Downstream 100 bases:

>100_bases
GACGGGATTCATAAAACATGGCTATTTCGAACAAACAAAAGGCTGCCATTGCGGCCATCGTACTGGTGGGCGGCGTCGCG
ACTGGTGGCGTTCTGCTGAG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Cation efflux system protein CzcC [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MRRLFLPLGLAVAFLSPNFAVAQSDTGTSMVPVFPREAAGPLTLEAALSLAAGSNFNLSAAAKELDSTEGGIMQARVIPN
PELQTLVEDTRKSTRTSTAQMNIPIELGGKRSARINAAERTRELAQATLAGVRGDIRAQVIESFFSVLIAQERVKLATGS
ADIAARGAQAASRRVAAGKISPVDETKARVEQANAELELAEATASLQSARQALTALWGNASPQFTEAQGNLDALPSRPAP
ELLLKELENSPLVAASRAELDRRQALVGVERSRQYPDLTVSLGAKRDTEANRNMAVIGVAIPLPIFDRNQGNLYSAIRQA
DKAQDEYLANRISLTRNLLMASNQLSVSRASAQTLKQTVLPGAEQAFNAATIGFEAGKFNYLDVLDAQRTLFQARIRYLG
VLGQTYQAATTIDRILGR

Sequences:

>Translated_418_residues
MRRLFLPLGLAVAFLSPNFAVAQSDTGTSMVPVFPREAAGPLTLEAALSLAAGSNFNLSAAAKELDSTEGGIMQARVIPN
PELQTLVEDTRKSTRTSTAQMNIPIELGGKRSARINAAERTRELAQATLAGVRGDIRAQVIESFFSVLIAQERVKLATGS
ADIAARGAQAASRRVAAGKISPVDETKARVEQANAELELAEATASLQSARQALTALWGNASPQFTEAQGNLDALPSRPAP
ELLLKELENSPLVAASRAELDRRQALVGVERSRQYPDLTVSLGAKRDTEANRNMAVIGVAIPLPIFDRNQGNLYSAIRQA
DKAQDEYLANRISLTRNLLMASNQLSVSRASAQTLKQTVLPGAEQAFNAATIGFEAGKFNYLDVLDAQRTLFQARIRYLG
VLGQTYQAATTIDRILGR
>Mature_418_residues
MRRLFLPLGLAVAFLSPNFAVAQSDTGTSMVPVFPREAAGPLTLEAALSLAAGSNFNLSAAAKELDSTEGGIMQARVIPN
PELQTLVEDTRKSTRTSTAQMNIPIELGGKRSARINAAERTRELAQATLAGVRGDIRAQVIESFFSVLIAQERVKLATGS
ADIAARGAQAASRRVAAGKISPVDETKARVEQANAELELAEATASLQSARQALTALWGNASPQFTEAQGNLDALPSRPAP
ELLLKELENSPLVAASRAELDRRQALVGVERSRQYPDLTVSLGAKRDTEANRNMAVIGVAIPLPIFDRNQGNLYSAIRQA
DKAQDEYLANRISLTRNLLMASNQLSVSRASAQTLKQTVLPGAEQAFNAATIGFEAGKFNYLDVLDAQRTLFQARIRYLG
VLGQTYQAATTIDRILGR

Specific function: CzcC protein appears to modify the specificity of the system, perhaps by acting on the CzcB protein. When the CzcC protein is added to CzcA and CzcB, the efflux system gains specificity for cadmium and cobalt [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 44822; Mature: 44822

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLFLPLGLAVAFLSPNFAVAQSDTGTSMVPVFPREAAGPLTLEAALSLAAGSNFNLSA
CCEEEHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCCEEHHHHHHHHCCCCCCHHH
AAKELDSTEGGIMQARVIPNPELQTLVEDTRKSTRTSTAQMNIPIELGGKRSARINAAER
HHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHH
TRELAQATLAGVRGDIRAQVIESFFSVLIAQERVKLATGSADIAARGAQAASRRVAAGKI
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHCHHCCCC
SPVDETKARVEQANAELELAEATASLQSARQALTALWGNASPQFTEAQGNLDALPSRPAP
CCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCH
ELLLKELENSPLVAASRAELDRRQALVGVERSRQYPDLTVSLGAKRDTEANRNMAVIGVA
HHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEEE
IPLPIFDRNQGNLYSAIRQADKAQDEYLANRISLTRNLLMASNQLSVSRASAQTLKQTVL
ECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
PGAEQAFNAATIGFEAGKFNYLDVLDAQRTLFQARIRYLGVLGQTYQAATTIDRILGR
CCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRLFLPLGLAVAFLSPNFAVAQSDTGTSMVPVFPREAAGPLTLEAALSLAAGSNFNLSA
CCEEEHHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCCEEHHHHHHHHCCCCCCHHH
AAKELDSTEGGIMQARVIPNPELQTLVEDTRKSTRTSTAQMNIPIELGGKRSARINAAER
HHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCHHHH
TRELAQATLAGVRGDIRAQVIESFFSVLIAQERVKLATGSADIAARGAQAASRRVAAGKI
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHCHHCCCC
SPVDETKARVEQANAELELAEATASLQSARQALTALWGNASPQFTEAQGNLDALPSRPAP
CCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCH
ELLLKELENSPLVAASRAELDRRQALVGVERSRQYPDLTVSLGAKRDTEANRNMAVIGVA
HHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEEEEE
IPLPIFDRNQGNLYSAIRQADKAQDEYLANRISLTRNLLMASNQLSVSRASAQTLKQTVL
ECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
PGAEQAFNAATIGFEAGKFNYLDVLDAQRTLFQARIRYLGVLGQTYQAATTIDRILGR
CCHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2678100; 7766206 [H]