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The map label for this gene is czcB [H]

Identifier: 187928846

GI number: 187928846

Start: 1861948

End: 1863510

Strand: Reverse

Name: czcB [H]

Synonym: Rpic_1763

Alternate gene names: 187928846

Gene position: 1863510-1861948 (Counterclockwise)

Preceding gene: 187928847

Following gene: 187928845

Centisome position: 47.27

GC content: 61.04

Gene sequence:

>1563_bases
ATGGCTATTTCGAACAAACAAAAGGCTGCCATTGCGGCCATCGTACTGGTGGGCGGCGTCGCGACTGGTGGCGTTCTGCT
GAGCGGGCGCTCTGCGCCGGAAGAGCAGGGTGGGCACTCGGAATCCAAGGGGCATGGCGACACCGAGCACCATGGCAAGC
AGGCGGCGGAAGCCGACCACAAGGATGACAAGTCACACGGCGACGGCGAGCATCACGAGGTCAAGAAGGGCCCCAATGGT
GGCGCGCTCTTTTCGCGTGATGGCTATGACGTCGAAATTGGCACGGCCGAATCCAAGGGCGAGGCCCGTATTCGGCTCTG
GGTTAGCAAGTCTGGGAAGGCGGTGGCAAATGGCGTGGCAGCGACAGGCCAGCTCGTGCGGGCTACGGGCGAGTCTCAAG
CGCTCAAGTTCGTGGTGTCTGGCGACGCGCTGGAAAGCCAACAGCCAGTTGCCGAGCCCCATGTCTTTGACGTGACCGCA
AATGTGACCTTGCCCGGTTCGTCTTCGCCACTCGCCGTGCGGCTCTCGAAAGAGGAAGGCAAGATTGAGTTGACAGCGGA
CCAGCTGGCCAAGACAGGGGTAGTGGTTCAAACCGCGGGCTCGGCAAAGGTCCAGGCTGGCGTCCAGTTCCCCGGCGAAA
TCCGTTTCAACGAAGACAAGACAGCCCACGTGGTGCCGCGACTGGCTGGCGTCGTAGAGAGCGTTCCGGCCAATATTGGG
CAACAGGTTAAGAAGGGACAGGTTCTCGCGGTCATCGCGAGCACCGGACTTTCTGACCAGCGCAGCGAACTGCTCGCAGC
ACAGAAACGTCTGGATCTGGCGCGTGTCACTTATGACCGCGAGAAGAAGCTCTGGGAACAGAAGATCTCTGCGGAGCAAG
ATTATCTGAGCGCCCGCAACGCGCTGCAGGAAGCGCAGATCAGTGTCCAGAACGCGCAGCAGAAGCTGACCGCCATTGGC
GCCAGCAACAGCTCGACGGCACTCAATCGCTACGAGCTGCGCGCACCGTTCGACGGCATGATCGTTGAAAAGCATATCTC
GCTTGGGGAAGCGGTGGCGGACAACGCCAACGTGTTCACGCTGTCGGATCTGTCGTCCGTCTGGGCCGAGTTCGTGGTGT
CTGCCAAGGATGTCGAGCGGGTGCGCATCGGCGAAAAGGCGTCGATCAATTCGGCATCGTCCGATGTGAAGGCAGATGGC
ACCGTTTCATACGTGGGTTCGCTGCTGGGCGAGCAGACGCGGACGGCGAAGGCCCGCGTAACATTGACCAATCCACAGAT
GGCTTGGCGACCGGGTCTCTTCGTCACGGTCGACGTATTCGGTGCTGATGTCGAGGTGCCCGTTGCGGTGAAGACCGAGG
CCGTCCAGGACGTCAATGGCGAGAGCGTAGTCTTTGTCGCGGTTCAAGGTGGATTCGTGCCGCAGCCGGTGAAGGTCGGC
CGGACAAACGGCAAGGTCATCGAGATTGTCGAGGGCCTGAAGCCGGGCGCACGTTACGCCGCCGCCAACAGTTTTGTTCT
GAAGGCCGAACTTGGCAAATCCAGCGCCGAACACGGCCATTGA

Upstream 100 bases:

>100_bases
TCCAGGCACGCATCCGCTATCTCGGCGTGCTTGGACAAACCTATCAGGCGGCGACCACGATCGATCGCATTCTGGGACGT
TAAGACGGGATTCATAAAAC

Downstream 100 bases:

>100_bases
TACGGGGGAAACAGCAATGTTTGAACGTATCATTAGTTTCGCCATCCAGCAGCGATGGCTGGTCCTGCTCGCCGTGTTTG
GAATGGCCGGGTTAGGGATT

Product: Membrane Fusion Protein cluster 2 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MAISNKQKAAIAAIVLVGGVATGGVLLSGRSAPEEQGGHSESKGHGDTEHHGKQAAEADHKDDKSHGDGEHHEVKKGPNG
GALFSRDGYDVEIGTAESKGEARIRLWVSKSGKAVANGVAATGQLVRATGESQALKFVVSGDALESQQPVAEPHVFDVTA
NVTLPGSSSPLAVRLSKEEGKIELTADQLAKTGVVVQTAGSAKVQAGVQFPGEIRFNEDKTAHVVPRLAGVVESVPANIG
QQVKKGQVLAVIASTGLSDQRSELLAAQKRLDLARVTYDREKKLWEQKISAEQDYLSARNALQEAQISVQNAQQKLTAIG
ASNSSTALNRYELRAPFDGMIVEKHISLGEAVADNANVFTLSDLSSVWAEFVVSAKDVERVRIGEKASINSASSDVKADG
TVSYVGSLLGEQTRTAKARVTLTNPQMAWRPGLFVTVDVFGADVEVPVAVKTEAVQDVNGESVVFVAVQGGFVPQPVKVG
RTNGKVIEIVEGLKPGARYAAANSFVLKAELGKSSAEHGH

Sequences:

>Translated_520_residues
MAISNKQKAAIAAIVLVGGVATGGVLLSGRSAPEEQGGHSESKGHGDTEHHGKQAAEADHKDDKSHGDGEHHEVKKGPNG
GALFSRDGYDVEIGTAESKGEARIRLWVSKSGKAVANGVAATGQLVRATGESQALKFVVSGDALESQQPVAEPHVFDVTA
NVTLPGSSSPLAVRLSKEEGKIELTADQLAKTGVVVQTAGSAKVQAGVQFPGEIRFNEDKTAHVVPRLAGVVESVPANIG
QQVKKGQVLAVIASTGLSDQRSELLAAQKRLDLARVTYDREKKLWEQKISAEQDYLSARNALQEAQISVQNAQQKLTAIG
ASNSSTALNRYELRAPFDGMIVEKHISLGEAVADNANVFTLSDLSSVWAEFVVSAKDVERVRIGEKASINSASSDVKADG
TVSYVGSLLGEQTRTAKARVTLTNPQMAWRPGLFVTVDVFGADVEVPVAVKTEAVQDVNGESVVFVAVQGGFVPQPVKVG
RTNGKVIEIVEGLKPGARYAAANSFVLKAELGKSSAEHGH
>Mature_519_residues
AISNKQKAAIAAIVLVGGVATGGVLLSGRSAPEEQGGHSESKGHGDTEHHGKQAAEADHKDDKSHGDGEHHEVKKGPNGG
ALFSRDGYDVEIGTAESKGEARIRLWVSKSGKAVANGVAATGQLVRATGESQALKFVVSGDALESQQPVAEPHVFDVTAN
VTLPGSSSPLAVRLSKEEGKIELTADQLAKTGVVVQTAGSAKVQAGVQFPGEIRFNEDKTAHVVPRLAGVVESVPANIGQ
QVKKGQVLAVIASTGLSDQRSELLAAQKRLDLARVTYDREKKLWEQKISAEQDYLSARNALQEAQISVQNAQQKLTAIGA
SNSSTALNRYELRAPFDGMIVEKHISLGEAVADNANVFTLSDLSSVWAEFVVSAKDVERVRIGEKASINSASSDVKADGT
VSYVGSLLGEQTRTAKARVTLTNPQMAWRPGLFVTVDVFGADVEVPVAVKTEAVQDVNGESVVFVAVQGGFVPQPVKVGR
TNGKVIEIVEGLKPGARYAAANSFVLKAELGKSSAEHGH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081796, Length=296, Percent_Identity=27.7027027027027, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 54632; Mature: 54501

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISNKQKAAIAAIVLVGGVATGGVLLSGRSAPEEQGGHSESKGHGDTEHHGKQAAEADH
CCCCCCHHHHHEEEEEECCCCCCCEEEECCCCCHHCCCCCCCCCCCCCHHHCCHHHCCCC
KDDKSHGDGEHHEVKKGPNGGALFSRDGYDVEIGTAESKGEARIRLWVSKSGKAVANGVA
CCCCCCCCCCCHHHCCCCCCCEEECCCCCEEEEECCCCCCCEEEEEEEECCCCHHHCCHH
ATGQLVRATGESQALKFVVSGDALESQQPVAEPHVFDVTANVTLPGSSSPLAVRLSKEEG
HCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEEECCCC
KIELTADQLAKTGVVVQTAGSAKVQAGVQFPGEIRFNEDKTAHVVPRLAGVVESVPANIG
EEEEEHHHHHHCCEEEEECCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
QQVKKGQVLAVIASTGLSDQRSELLAAQKRLDLARVTYDREKKLWEQKISAEQDYLSARN
HHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ALQEAQISVQNAQQKLTAIGASNSSTALNRYELRAPFDGMIVEKHISLGEAVADNANVFT
HHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEECCCCCCEEEEEHHHHCHHHCCCCCEEE
LSDLSSVWAEFVVSAKDVERVRIGEKASINSASSDVKADGTVSYVGSLLGEQTRTAKARV
EHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEE
TLTNPQMAWRPGLFVTVDVFGADVEVPVAVKTEAVQDVNGESVVFVAVQGGFVPQPVKVG
EEECCCCEECCCCEEEEEEECCCEEEEEEEEHHHHHCCCCCEEEEEEEECCCCCCCEEEC
RTNGKVIEIVEGLKPGARYAAANSFVLKAELGKSSAEHGH
CCCCCEEEEECCCCCCCCEECCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
AISNKQKAAIAAIVLVGGVATGGVLLSGRSAPEEQGGHSESKGHGDTEHHGKQAAEADH
CCCCCHHHHHEEEEEECCCCCCCEEEECCCCCHHCCCCCCCCCCCCCHHHCCHHHCCCC
KDDKSHGDGEHHEVKKGPNGGALFSRDGYDVEIGTAESKGEARIRLWVSKSGKAVANGVA
CCCCCCCCCCCHHHCCCCCCCEEECCCCCEEEEECCCCCCCEEEEEEEECCCCHHHCCHH
ATGQLVRATGESQALKFVVSGDALESQQPVAEPHVFDVTANVTLPGSSSPLAVRLSKEEG
HCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEEEECCCC
KIELTADQLAKTGVVVQTAGSAKVQAGVQFPGEIRFNEDKTAHVVPRLAGVVESVPANIG
EEEEEHHHHHHCCEEEEECCCCEEEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
QQVKKGQVLAVIASTGLSDQRSELLAAQKRLDLARVTYDREKKLWEQKISAEQDYLSARN
HHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ALQEAQISVQNAQQKLTAIGASNSSTALNRYELRAPFDGMIVEKHISLGEAVADNANVFT
HHHHHHHHHHHHHHHHHEECCCCCCCCEEEEEECCCCCCEEEEEHHHHCHHHCCCCCEEE
LSDLSSVWAEFVVSAKDVERVRIGEKASINSASSDVKADGTVSYVGSLLGEQTRTAKARV
EHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEE
TLTNPQMAWRPGLFVTVDVFGADVEVPVAVKTEAVQDVNGESVVFVAVQGGFVPQPVKVG
EEECCCCEECCCCEEEEEEECCCEEEEEEEEHHHHHCCCCCEEEEEEEECCCCCCCEEEC
RTNGKVIEIVEGLKPGARYAAANSFVLKAELGKSSAEHGH
CCCCCEEEEECCCCCCCCEECCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]