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The map label for this gene is ttuB [H]

Identifier: 187927610

GI number: 187927610

Start: 547462

End: 548784

Strand: Reverse

Name: ttuB [H]

Synonym: Rpic_0510

Alternate gene names: 187927610

Gene position: 548784-547462 (Counterclockwise)

Preceding gene: 187927611

Following gene: 187927607

Centisome position: 13.92

GC content: 64.63

Gene sequence:

>1323_bases
ATGTCGCAAACCCAAGCCCTTCCGGCCAACCCAACAGACCCGACCAGCCAGTCCATCCCCAGCACCGAGCTGGATGTCAC
CTACCGGCGCATTGCGTATCGGCTGGTGCCGTTCCTGGTGGTGCTGTTCATCCTCGCGTGGATCGACCGCGTCAATGTCG
GCTTTGCCAAGCTGTCGATGCTGCAGGATCTGCAGTTCAGCGAAGCGGTGTACGGCCTGGGCGCGGGCATCTTCTTCATC
GGCTACTTCCTGTTTGAAGTGCCGAGCAACCTGCTGCTGGAAAAGATCGGCGCCCGCAAGACGCTGGCACGCATCACCAT
CCTGTGGGGCCTGGCCTCGATGGCGATGATCTACGTGAAGACGCCGACCTCGTTCTACGTGATGCGCTTTCTGCTGGGCA
TCTTTGAAGCCGGCTTCTTCCCGGGCGTGGTGCTGTACCTGACGTACTGGTTTCCCTCCGCACACCGCGCGCGCATCAAC
GGCCTGTTCATGACGTCGTTTGCGATTGCGGGCGTGGTGGGCGGCCCAGTTGCGGGTTTCATCATGAGCCGCATGGAAGG
CGTGGGCCACCTCGCCAACTGGCAATGGCTGTTCCTGCTCGAAGGCATTCCTTCCGTGCTGGCCGGCTTTGCCGTGCTTG
CATGGCTGCCCGAAACGCCTCGCCAGGCCAAGTGGCTTTCCGCTGCCGAGCAAGACGCCGTCGTCCGCGCCGTTGAAGCG
GAGAATCGCGACCCTGCCAAGCACGCCTCGTTTGGTGCGGCACTCGCCAACGCCCGCGTGTGGGTCTGTGCAGCCATCTA
CTTCTGCGTGGTCAGCGGCAACGCCACCATCGCGTTCTGGACGCCGTCGATCATCAAGGAGCTGGGCGTGCAGGGCAATT
TCCAGATCGGGCTGATCTCGGCCATTCCGTTCATCGCCGGCACGATTGCGATGGTGTGGAACGGCGCGCATTCCGACCGC
ACGGGCGAACGCCGCATGCACTGCGCCATCGCCGCCCTCATCGCCAGCGCCGGCCTGGTGGCGACAGGCGCTACGCTGGG
CTCGCCGTTTCTGGCGCTGGTCTCGCTGACGGTCGCCGCCATCGGCATCCTCGCCGCGTTCCCGGTGTTCTGGTCGATCC
CGGCCGTGTTCCTGGCCGGCACCGCAGCCGCAGGCGGCATCGCCCTCATCAACTCCATCGGCAACCTCGCCGGCTTCGTC
GCGCCGTACATGATCGGCTGGCTGAAGACAAGCACCGGCCATCTCTCCGCCGGCCTCTACTTCGTAGCCGCGCTGGAGCT
GGGCGCCGCCGTGCTGGTCATCCTAGGCACGCGCAAACACTAA

Upstream 100 bases:

>100_bases
GGCGCGCTGCAGACGCGCCAGGCCCAACTCATGCCTGCGTTTCGGACAACAAGGCAGCACAACGAAACGCCGGCGCCCGC
ACACGCTATTGGAGGAAACC

Downstream 100 bases:

>100_bases
GCACGCAGACGAACCATCGCGGCGCCAACTCCCGCGCCGCGATGGTTTGGCGGTTGACGTTCCTGCCCTAGATGGCGCCT
TGAATTTCTGTAAGCGGGCG

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSQTQALPANPTDPTSQSIPSTELDVTYRRIAYRLVPFLVVLFILAWIDRVNVGFAKLSMLQDLQFSEAVYGLGAGIFFI
GYFLFEVPSNLLLEKIGARKTLARITILWGLASMAMIYVKTPTSFYVMRFLLGIFEAGFFPGVVLYLTYWFPSAHRARIN
GLFMTSFAIAGVVGGPVAGFIMSRMEGVGHLANWQWLFLLEGIPSVLAGFAVLAWLPETPRQAKWLSAAEQDAVVRAVEA
ENRDPAKHASFGAALANARVWVCAAIYFCVVSGNATIAFWTPSIIKELGVQGNFQIGLISAIPFIAGTIAMVWNGAHSDR
TGERRMHCAIAALIASAGLVATGATLGSPFLALVSLTVAAIGILAAFPVFWSIPAVFLAGTAAAGGIALINSIGNLAGFV
APYMIGWLKTSTGHLSAGLYFVAALELGAAVLVILGTRKH

Sequences:

>Translated_440_residues
MSQTQALPANPTDPTSQSIPSTELDVTYRRIAYRLVPFLVVLFILAWIDRVNVGFAKLSMLQDLQFSEAVYGLGAGIFFI
GYFLFEVPSNLLLEKIGARKTLARITILWGLASMAMIYVKTPTSFYVMRFLLGIFEAGFFPGVVLYLTYWFPSAHRARIN
GLFMTSFAIAGVVGGPVAGFIMSRMEGVGHLANWQWLFLLEGIPSVLAGFAVLAWLPETPRQAKWLSAAEQDAVVRAVEA
ENRDPAKHASFGAALANARVWVCAAIYFCVVSGNATIAFWTPSIIKELGVQGNFQIGLISAIPFIAGTIAMVWNGAHSDR
TGERRMHCAIAALIASAGLVATGATLGSPFLALVSLTVAAIGILAAFPVFWSIPAVFLAGTAAAGGIALINSIGNLAGFV
APYMIGWLKTSTGHLSAGLYFVAALELGAAVLVILGTRKH
>Mature_439_residues
SQTQALPANPTDPTSQSIPSTELDVTYRRIAYRLVPFLVVLFILAWIDRVNVGFAKLSMLQDLQFSEAVYGLGAGIFFIG
YFLFEVPSNLLLEKIGARKTLARITILWGLASMAMIYVKTPTSFYVMRFLLGIFEAGFFPGVVLYLTYWFPSAHRARING
LFMTSFAIAGVVGGPVAGFIMSRMEGVGHLANWQWLFLLEGIPSVLAGFAVLAWLPETPRQAKWLSAAEQDAVVRAVEAE
NRDPAKHASFGAALANARVWVCAAIYFCVVSGNATIAFWTPSIIKELGVQGNFQIGLISAIPFIAGTIAMVWNGAHSDRT
GERRMHCAIAALIASAGLVATGATLGSPFLALVSLTVAAIGILAAFPVFWSIPAVFLAGTAAAGGIALINSIGNLAGFVA
PYMIGWLKTSTGHLSAGLYFVAALELGAAVLVILGTRKH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=403, Percent_Identity=38.2133995037221, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI2367379, Length=452, Percent_Identity=23.8938053097345, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789515, Length=450, Percent_Identity=23.7777777777778, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082320, Length=442, Percent_Identity=22.8506787330317, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789152, Length=451, Percent_Identity=21.2860310421286, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322025, Length=189, Percent_Identity=27.5132275132275, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319876, Length=263, Percent_Identity=27.7566539923954, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6321698, Length=353, Percent_Identity=22.9461756373938, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322612, Length=251, Percent_Identity=24.3027888446215, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6323032, Length=216, Percent_Identity=27.3148148148148, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324410, Length=148, Percent_Identity=28.3783783783784, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321502, Length=225, Percent_Identity=26.2222222222222, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584153, Length=360, Percent_Identity=21.6666666666667, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24648416, Length=400, Percent_Identity=24.25, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356189, Length=400, Percent_Identity=24.25, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24583789, Length=381, Percent_Identity=22.0472440944882, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47041; Mature: 46910

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHEEEEEECCCCC
>Mature Secondary Structure 
SQTQALPANPTDPTSQSIPSTELDVTYRRIAYRLVPFLVVLFILAWIDRVNVGFAKLSM
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LQDLQFSEAVYGLGAGIFFIGYFLFEVPSNLLLEKIGARKTLARITILWGLASMAMIYVK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEE
TPTSFYVMRFLLGIFEAGFFPGVVLYLTYWFPSAHRARINGLFMTSFAIAGVVGGPVAGF
CCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHH
IMSRMEGVGHLANWQWLFLLEGIPSVLAGFAVLAWLPETPRQAKWLSAAEQDAVVRAVEA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
ENRDPAKHASFGAALANARVWVCAAIYFCVVSGNATIAFWTPSIIKELGVQGNFQIGLIS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCCCCEEEHHH
AIPFIAGTIAMVWNGAHSDRTGERRMHCAIAALIASAGLVATGATLGSPFLALVSLTVAA
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCHHCHHHHHHHHHHHHH
IGILAAFPVFWSIPAVFLAGTAAAGGIALINSIGNLAGFVAPYMIGWLKTSTGHLSAGLY
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
FVAALELGAAVLVILGTRKH
HHHHHHHHHEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]