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The map label for this gene is grxC [H]

Identifier: 187927319

GI number: 187927319

Start: 228702

End: 228959

Strand: Direct

Name: grxC [H]

Synonym: Rpic_0211

Alternate gene names: 187927319

Gene position: 228702-228959 (Clockwise)

Preceding gene: 187927318

Following gene: 187927320

Centisome position: 5.8

GC content: 61.63

Gene sequence:

>258_bases
ATGGCGCACGTGGTCATGTACAGCACCACCGTCTGCCCCTATTGCGTGGCAGCGGAACGACTCCTGAAGCAGCGCGGTGT
TGAGCAGATCGAGAAGATCCTGATCGACCGCGAACCCGGAAAGCGCGAAGAGATGATGACGCGCACGAACCGCCGCACGG
TTCCGCAGATCTACATCGACGAGCGCCACATCGGCGGCTTCGACGATCTGTCTGCGCTGGACCGCGAAGGTGGCTTGGTT
CCGTTGCTGGCTGCTTGA

Upstream 100 bases:

>100_bases
GCAGGCCGGTTACAGTGAGGTGTATTCGCTGGAGGGCGGATTGGCCGCCTGGCAACAAGCTGGCCTTCCGGTTGTGAAAT
AAAGAAACGAGGTTGAAGTT

Downstream 100 bases:

>100_bases
TTCGGCGGACTGCGCACCACACAGAAATGCCCGGCTTAGACCGGGCGTTGTACTTTCAGGCCGGCTCTCATAGCGGGCAC
CATCTGGTCATGTACCATAC

Product: glutaredoxin 3

Products: NA

Alternate protein names: Grx3 [H]

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MAHVVMYSTTVCPYCVAAERLLKQRGVEQIEKILIDREPGKREEMMTRTNRRTVPQIYIDERHIGGFDDLSALDREGGLV
PLLAA

Sequences:

>Translated_85_residues
MAHVVMYSTTVCPYCVAAERLLKQRGVEQIEKILIDREPGKREEMMTRTNRRTVPQIYIDERHIGGFDDLSALDREGGLV
PLLAA
>Mature_84_residues
AHVVMYSTTVCPYCVAAERLLKQRGVEQIEKILIDREPGKREEMMTRTNRRTVPQIYIDERHIGGFDDLSALDREGGLVP
LLAA

Specific function: The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing some disulfides in a coupled system with glutathione re

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=54.2168674698795, Blast_Score=91, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9672; Mature: 9541

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHVVMYSTTVCPYCVAAERLLKQRGVEQIEKILIDREPGKREEMMTRTNRRTVPQIYID
CCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEC
ERHIGGFDDLSALDREGGLVPLLAA
CCCCCCCCHHHHHHCCCCEEEEECC
>Mature Secondary Structure 
AHVVMYSTTVCPYCVAAERLLKQRGVEQIEKILIDREPGKREEMMTRTNRRTVPQIYID
CEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCEEEEC
ERHIGGFDDLSALDREGGLVPLLAA
CCCCCCCCHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]