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The map label for this gene is argS [H]

Identifier: 187927245

GI number: 187927245

Start: 156788

End: 158578

Strand: Reverse

Name: argS [H]

Synonym: Rpic_0137

Alternate gene names: 187927245

Gene position: 158578-156788 (Counterclockwise)

Preceding gene: 187927247

Following gene: 187927244

Centisome position: 4.02

GC content: 67.5

Gene sequence:

>1791_bases
ATGCTGCCCTCCCACAAACAGACGATCGCCCAACTGTTGTCCGACGCCGTCGGCTCCCTGCTGCCCGAGGGCCAAGCCCG
ACCGGAGATCGTCCTGGAGCGCCCCAAGCAGGCCGCGCACGGCGACATCGCCTGCAACGTCGCGCTGCAGCTCGCCAAAC
CCCTGGGCACCAACCCGCGCGAGTTGGCCGGCAAGATCGCCGATGCCATCCGCGCCGATGCCCGCGGCCAGCGCTTGGTG
GCCGCCGTGGAGATCGCTGGCCCCGGTTTCATCAACCTGCGCCTGTCCGCCGCCGCGCGTGCCGACGTGATCGCCGCCGT
GTTTGCAGAAGGCGACCGCTATGGCGCCGCAAACACGCATGACGGCGCGCCGGTGCTGGTGGAGTTTGTCTCGGCCAACC
CGACCGGTCCGCTGCACGTCGGTCACGGCCGCCAGGCCGCGCTGGGCGATGCGCTGGCGAGCCTGCTCGACTGGCAGGGC
CACAAGGTCCACCGCGAGTTCTACTACAACGACGCCGGCGTCCAGATCCACAACCTCGCCGTCTCCGTCCAGGCCCGCGC
ACGCGGCTACAAGCCGGGCGACGCCAACTGGCCCGAAGCCGCTTACAACGGCGACTACATTGCCGACATCGCCGCCGATT
ATCTCGCCGGCAAGACCGTGCGCGCCTCCGATGGCGAACCCGTGACGGGCGAGCGCGATGTCGAGAACATCGAAGCCATC
CGCCGCTTTGCCGTCACGTATCTGCGCAATGAGCAGGACATCGATCTGCAGGCCTTTGGCGTGAAGTTCGACCGCTACTA
CCTGGAGTCTTCGCTCTACACCGAAGGCAAGGTGCAGCAGACGGTAGACGCGCTCGTTGCTGCAGGCAAGACCTACGAGC
AGGAAGGCGCGCTGTGGCTGCGCACCACCGACGACGGTGACGACAAGGACCGCGTCATGCGCAAATCCGACGGCGCCTAC
ACCTACTTCGTGCCCGACGTTGCGTACCACACGACCAAATGGGGACGCGGCTTCACGCAGGTCATCAATGTGCAGGGCAG
CGACCACCACGGCACCATCGCCCGCGTGCGCGCCGGCCTGCAGGGCCTGAACATCGGCATCCCGAAGGGCTACCCCGATT
ACGTCCTGCACAAGATGGTCACGGTGATGAAGGACGGCGCCGAGGTGAAGATCTCCAAGCGCGCCGGCTCGTACGTGACG
GTGCGCGACCTGATCGAATGGTCCAACGGCGACGCCGAGAGCGAAGCCGGCGTCGACACCATCCGCGCCTGCGTGGAAGC
CGGCGAGCCGAACTGGCCGGCGCGCTTCACGCGTGGCCGCGACGCCGTGCGCTTCTTCCTGCTGTCGCGCAAGGCCGATA
CCGAATTCGTCTTCGACGTCGATCTGGCGCTCAAACAGAGCGACGAGAACCCCGTGTATTACGTGCAGTACGCGCACGCG
CGCATCTGCTCGGTGTTCGAGCGTGCAGGCGTTGACGCCGCCTCGCTCACCAGCGCTGATCTGGCTGCGGTGACGGGCCC
GGATGTCAGCCCGCAGGCGACCGCCCTGGTGCAACGCCTGGCCGCATTCCCCGACATGCTGGCCGACGCCGCACGCGAGC
TGGCCCCGCACGCCGTGGCTTTCTACCTGCGCGACCTGGCAGGCGATTTCCACGCGTTCTACAACGCCGATCGCGTGCTG
GTCGACGACGAGGCCGTCAAGCGTGCCCGCCTGGCGCTGCTGGCTGCCACGCGTCAGGTGCTGCGCAACGGGCTGGCGGT
GATCGGCGTGTCCGCGCCGCAAAAGATGTAA

Upstream 100 bases:

>100_bases
TCACCTGATAAAATTTCGTACTTTTCCCCGAACAACGCAACTGGCGGCGCCAGAACTGGATTTCAATCCAATTCAGCACT
GCCGGCGTCATGGTTTCTTT

Downstream 100 bases:

>100_bases
ACGCGCACGATTTGGCATCACACGGCGCTCTTATAATCGGGCGCTTCTAGAAGGATCGACATGGCACGCAATACGCAATT
TTCCCGTGCCCGCTCGCAAC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MLPSHKQTIAQLLSDAVGSLLPEGQARPEIVLERPKQAAHGDIACNVALQLAKPLGTNPRELAGKIADAIRADARGQRLV
AAVEIAGPGFINLRLSAAARADVIAAVFAEGDRYGAANTHDGAPVLVEFVSANPTGPLHVGHGRQAALGDALASLLDWQG
HKVHREFYYNDAGVQIHNLAVSVQARARGYKPGDANWPEAAYNGDYIADIAADYLAGKTVRASDGEPVTGERDVENIEAI
RRFAVTYLRNEQDIDLQAFGVKFDRYYLESSLYTEGKVQQTVDALVAAGKTYEQEGALWLRTTDDGDDKDRVMRKSDGAY
TYFVPDVAYHTTKWGRGFTQVINVQGSDHHGTIARVRAGLQGLNIGIPKGYPDYVLHKMVTVMKDGAEVKISKRAGSYVT
VRDLIEWSNGDAESEAGVDTIRACVEAGEPNWPARFTRGRDAVRFFLLSRKADTEFVFDVDLALKQSDENPVYYVQYAHA
RICSVFERAGVDAASLTSADLAAVTGPDVSPQATALVQRLAAFPDMLADAARELAPHAVAFYLRDLAGDFHAFYNADRVL
VDDEAVKRARLALLAATRQVLRNGLAVIGVSAPQKM

Sequences:

>Translated_596_residues
MLPSHKQTIAQLLSDAVGSLLPEGQARPEIVLERPKQAAHGDIACNVALQLAKPLGTNPRELAGKIADAIRADARGQRLV
AAVEIAGPGFINLRLSAAARADVIAAVFAEGDRYGAANTHDGAPVLVEFVSANPTGPLHVGHGRQAALGDALASLLDWQG
HKVHREFYYNDAGVQIHNLAVSVQARARGYKPGDANWPEAAYNGDYIADIAADYLAGKTVRASDGEPVTGERDVENIEAI
RRFAVTYLRNEQDIDLQAFGVKFDRYYLESSLYTEGKVQQTVDALVAAGKTYEQEGALWLRTTDDGDDKDRVMRKSDGAY
TYFVPDVAYHTTKWGRGFTQVINVQGSDHHGTIARVRAGLQGLNIGIPKGYPDYVLHKMVTVMKDGAEVKISKRAGSYVT
VRDLIEWSNGDAESEAGVDTIRACVEAGEPNWPARFTRGRDAVRFFLLSRKADTEFVFDVDLALKQSDENPVYYVQYAHA
RICSVFERAGVDAASLTSADLAAVTGPDVSPQATALVQRLAAFPDMLADAARELAPHAVAFYLRDLAGDFHAFYNADRVL
VDDEAVKRARLALLAATRQVLRNGLAVIGVSAPQKM
>Mature_596_residues
MLPSHKQTIAQLLSDAVGSLLPEGQARPEIVLERPKQAAHGDIACNVALQLAKPLGTNPRELAGKIADAIRADARGQRLV
AAVEIAGPGFINLRLSAAARADVIAAVFAEGDRYGAANTHDGAPVLVEFVSANPTGPLHVGHGRQAALGDALASLLDWQG
HKVHREFYYNDAGVQIHNLAVSVQARARGYKPGDANWPEAAYNGDYIADIAADYLAGKTVRASDGEPVTGERDVENIEAI
RRFAVTYLRNEQDIDLQAFGVKFDRYYLESSLYTEGKVQQTVDALVAAGKTYEQEGALWLRTTDDGDDKDRVMRKSDGAY
TYFVPDVAYHTTKWGRGFTQVINVQGSDHHGTIARVRAGLQGLNIGIPKGYPDYVLHKMVTVMKDGAEVKISKRAGSYVT
VRDLIEWSNGDAESEAGVDTIRACVEAGEPNWPARFTRGRDAVRFFLLSRKADTEFVFDVDLALKQSDENPVYYVQYAHA
RICSVFERAGVDAASLTSADLAAVTGPDVSPQATALVQRLAAFPDMLADAARELAPHAVAFYLRDLAGDFHAFYNADRVL
VDDEAVKRARLALLAATRQVLRNGLAVIGVSAPQKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=597, Percent_Identity=24.1206030150754, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI1788184, Length=584, Percent_Identity=29.4520547945205, Blast_Score=160, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6320548, Length=570, Percent_Identity=26.3157894736842, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI18859963, Length=625, Percent_Identity=23.68, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 64626; Mature: 64626

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSHKQTIAQLLSDAVGSLLPEGQARPEIVLERPKQAAHGDIACNVALQLAKPLGTNPR
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCCCEEEHHHHHHHHCCCCCHH
ELAGKIADAIRADARGQRLVAAVEIAGPGFINLRLSAAARADVIAAVFAEGDRYGAANTH
HHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCC
DGAPVLVEFVSANPTGPLHVGHGRQAALGDALASLLDWQGHKVHREFYYNDAGVQIHNLA
CCCCEEEEEECCCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEHHEEECCCCCEEEEEE
VSVQARARGYKPGDANWPEAAYNGDYIADIAADYLAGKTVRASDGEPVTGERDVENIEAI
EEEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHH
RRFAVTYLRNEQDIDLQAFGVKFDRYYLESSLYTEGKVQQTVDALVAAGKTYEQEGALWL
HHHHHHHHCCCCCCCEEEECEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEE
RTTDDGDDKDRVMRKSDGAYTYFVPDVAYHTTKWGRGFTQVINVQGSDHHGTIARVRAGL
EECCCCCCHHHHHHCCCCEEEEEECCHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCC
QGLNIGIPKGYPDYVLHKMVTVMKDGAEVKISKRAGSYVTVRDLIEWSNGDAESEAGVDT
CCCEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHCCCCCCCCCCCHHH
IRACVEAGEPNWPARFTRGRDAVRFFLLSRKADTEFVFDVDLALKQSDENPVYYVQYAHA
HHHHHHCCCCCCCCHHCCCHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEEEEHHH
RICSVFERAGVDAASLTSADLAAVTGPDVSPQATALVQRLAAFPDMLADAARELAPHAVA
HHHHHHHHHCCCHHHCCCCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYLRDLAGDFHAFYNADRVLVDDEAVKRARLALLAATRQVLRNGLAVIGVSAPQKM
HHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MLPSHKQTIAQLLSDAVGSLLPEGQARPEIVLERPKQAAHGDIACNVALQLAKPLGTNPR
CCCCHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCCCEEEHHHHHHHHCCCCCHH
ELAGKIADAIRADARGQRLVAAVEIAGPGFINLRLSAAARADVIAAVFAEGDRYGAANTH
HHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCC
DGAPVLVEFVSANPTGPLHVGHGRQAALGDALASLLDWQGHKVHREFYYNDAGVQIHNLA
CCCCEEEEEECCCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEHHEEECCCCCEEEEEE
VSVQARARGYKPGDANWPEAAYNGDYIADIAADYLAGKTVRASDGEPVTGERDVENIEAI
EEEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHH
RRFAVTYLRNEQDIDLQAFGVKFDRYYLESSLYTEGKVQQTVDALVAAGKTYEQEGALWL
HHHHHHHHCCCCCCCEEEECEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEE
RTTDDGDDKDRVMRKSDGAYTYFVPDVAYHTTKWGRGFTQVINVQGSDHHGTIARVRAGL
EECCCCCCHHHHHHCCCCEEEEEECCHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCC
QGLNIGIPKGYPDYVLHKMVTVMKDGAEVKISKRAGSYVTVRDLIEWSNGDAESEAGVDT
CCCEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHCCCCCCCCCCCHHH
IRACVEAGEPNWPARFTRGRDAVRFFLLSRKADTEFVFDVDLALKQSDENPVYYVQYAHA
HHHHHHCCCCCCCCHHCCCHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCCEEEEEEHHH
RICSVFERAGVDAASLTSADLAAVTGPDVSPQATALVQRLAAFPDMLADAARELAPHAVA
HHHHHHHHHCCCHHHCCCCCHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYLRDLAGDFHAFYNADRVLVDDEAVKRARLALLAATRQVLRNGLAVIGVSAPQKM
HHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]