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The map label for this gene is toxB [H]

Identifier: 187935530

GI number: 187935530

Start: 3375251

End: 3377452

Strand: Reverse

Name: toxB [H]

Synonym: CLL_A3230

Alternate gene names: 187935530

Gene position: 3377452-3375251 (Counterclockwise)

Preceding gene: 187934696

Following gene: 187932622

Centisome position: 88.87

GC content: 30.47

Gene sequence:

>2202_bases
TTGTTAATATTGACAGTTATGGTAACAGGAATTCAACTTGGTAATATTAAATCTGCAAGTGCAGTGGAATTAAATTTAGG
ATTTGTTGTAGAAGCGGGTGGAGCTAATTTAGATATTAATAAGAGTTCTTCTAACGCTTATTATACGGATGAAATTGATA
TGTCAGTATCAACTATTAATATAAAATCAAGTGATACGTCATATTACAAATTAGAGGGTGTTACTTCTAGTTCGAGTGGG
GTAAAAATTGCAAGTTCAACAACTAATGGGATTACAAGTTATAAAATAGCTGTAACTAAATATAATGATTTTAATGCTAC
TATTAAAGTAAAAGATTTAGGAACTCAAGAAGTTAAATCTTATAATGTTACATTTAAATTTAAAGAAGAAAATGCTGATA
CTTTTAAATTTAACAAAATCATGATAGTTGCATCTGGTAGTGGCGGACCAATGACTCTTGATTTAGACTATAATTCTGAT
GGTGATGATTACTATATCTCAGGTTTAGGTGACGATATAGACACTGCTAAAGTTAGTATTGTAGATGAAAATGGTAAGGC
TATAACTTCAGGTGTTAAAATTACTATGGATGGTAAGACAGGTACATTTAAGTTATTAGGTGGGGAAAATGAAATACTTA
TAAGTAGAACAGTTAATGGACGTACTAAGACATTTAAACTTGTAATTGCTAAAAAAGGCAGTGCTAAATTAAAGTCTTTA
ACAGGTGTAACATTATCACCTAGGTTTGATTCAGAAACTACAGATTATACAGCTACTGTTCCAACAGCAACAGATAAGGT
TGTATTAAAACCAACAGCAGCAGATAATTCATCTACTATAAGAATAAATGGTGTTCTTGTAACTAGTGGAGCTAATAGTC
AACCTATATCATTAAAAGAAGGTAAGAATGATATAACGATTAGAGTAACTACAAAAGATGGTGAAGTTGGAGTTTATAAT
TTAGAGGTTACTAGAACTGAAGCACCAAGAAGTTCTTACTTAAAATATTTAAAAATAAATTCAGCATCACTTTCACCATC
ATTTAATAAACAAACTTTTGATTATACAGCTACAGTTGAAAATAAAGTAACTGCTGTAACTATTACTCCAACAGCTGAAT
ATGCTACATCAACTATTAAGGTTAATGGCAAAACTGTTGTAAGTGGAGGAACTACAGGTTATATTAGTTTAGATGAAGGT
TCTAACGAAATAGAAATAAAAGTTACTGATGCTAAAGGTGATACTAGTACTTATGATATAGTTATTACAAGAAGATATGG
AAAAGATAATGTGAAACTTTCAAATCTTAAGAGTACAGAAGGAACTTTATCACCAAAATTTGATCCAGAAACATATCTTT
ATACTGTAAAAGTGGACAGGGCTGTAGGAAGAACTAAAATTGTATTTAAAGCTCAAAATGATAAAGCAACTATAAAGGTA
AATGGCAAGGAATATACAAGTGCACAAGAATCTGATTATATTGATTTAAAGATAGGTGCAAATCTTATTAATATTGAAGT
TGTAGCAGAAGATAAGAAAACTACTACTTTATATAGGGTAAGTGTAATTAGAGATAAAATACAAGCTATTAATGAATGGG
TTTTATCAGGTGATGATTGGACATTCTATGATGCATTAGGATATCAAGTAAAAAATAAGTGGGTTAAATATGATAATCAA
TGGTATTTTGTAAATATCAATGGATATATGGAAAAGAACGGCTGGCTTAACGAAAGTGGAGAATGGTACTATCTAAATGG
AGATGGAACTATGAAAACTGGTTGGTTCAAGGATAATGGATATTGGTATTATCTTCAAGGCGATGGAAAGATGAAAAATT
CTGGCTGGGGATATTATGATAAAGAATGGTACATGTTTGGACCTAATGGAATGTTAGAAACAGGTTGGAAACAACATAAA
GGTAATTGGTATTTCTTATTAGACAACGGTACTATGAGAAGAGGCTGGCAATATTATGATTTAAATTGGTACTATTTAAA
TGATGATGGAATAATGAAAAGAGGCTGGCTATATGATGGAAAGAATTATTACTATTTAAATAATAGCGGTGTAATGAAGA
CCGGCTGGCAAAGAATAAATAGTAAAGATTATTACTTTGATTCTTCAGGAAAGATGAAGACAGGATATATATTCTTAGAT
GGTAAGTGGTATAACTTAGGACAAGATGGTTCGTTAAATTAA

Upstream 100 bases:

>100_bases
TAATTTACTAAGAAAAGGGGAGGAGGAAATTGCTAAAATTAATGTTAATTTAGCAATAAAATAAATAATGAAAATTAATT
TTAAAAGAGTTATTTCACAA

Downstream 100 bases:

>100_bases
TTATCCTTGGCTATCTAGTGACAGTGACTAAAAAAATGCTATGAGCTTTGCTTATGGCATTTTTTTGCGCAAAAATTGTG
ACAGTAGCAATTGATAAAAT

Product: collagenolytic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 733; Mature: 733

Protein sequence:

>733_residues
MLILTVMVTGIQLGNIKSASAVELNLGFVVEAGGANLDINKSSSNAYYTDEIDMSVSTINIKSSDTSYYKLEGVTSSSSG
VKIASSTTNGITSYKIAVTKYNDFNATIKVKDLGTQEVKSYNVTFKFKEENADTFKFNKIMIVASGSGGPMTLDLDYNSD
GDDYYISGLGDDIDTAKVSIVDENGKAITSGVKITMDGKTGTFKLLGGENEILISRTVNGRTKTFKLVIAKKGSAKLKSL
TGVTLSPRFDSETTDYTATVPTATDKVVLKPTAADNSSTIRINGVLVTSGANSQPISLKEGKNDITIRVTTKDGEVGVYN
LEVTRTEAPRSSYLKYLKINSASLSPSFNKQTFDYTATVENKVTAVTITPTAEYATSTIKVNGKTVVSGGTTGYISLDEG
SNEIEIKVTDAKGDTSTYDIVITRRYGKDNVKLSNLKSTEGTLSPKFDPETYLYTVKVDRAVGRTKIVFKAQNDKATIKV
NGKEYTSAQESDYIDLKIGANLINIEVVAEDKKTTTLYRVSVIRDKIQAINEWVLSGDDWTFYDALGYQVKNKWVKYDNQ
WYFVNINGYMEKNGWLNESGEWYYLNGDGTMKTGWFKDNGYWYYLQGDGKMKNSGWGYYDKEWYMFGPNGMLETGWKQHK
GNWYFLLDNGTMRRGWQYYDLNWYYLNDDGIMKRGWLYDGKNYYYLNNSGVMKTGWQRINSKDYYFDSSGKMKTGYIFLD
GKWYNLGQDGSLN

Sequences:

>Translated_733_residues
MLILTVMVTGIQLGNIKSASAVELNLGFVVEAGGANLDINKSSSNAYYTDEIDMSVSTINIKSSDTSYYKLEGVTSSSSG
VKIASSTTNGITSYKIAVTKYNDFNATIKVKDLGTQEVKSYNVTFKFKEENADTFKFNKIMIVASGSGGPMTLDLDYNSD
GDDYYISGLGDDIDTAKVSIVDENGKAITSGVKITMDGKTGTFKLLGGENEILISRTVNGRTKTFKLVIAKKGSAKLKSL
TGVTLSPRFDSETTDYTATVPTATDKVVLKPTAADNSSTIRINGVLVTSGANSQPISLKEGKNDITIRVTTKDGEVGVYN
LEVTRTEAPRSSYLKYLKINSASLSPSFNKQTFDYTATVENKVTAVTITPTAEYATSTIKVNGKTVVSGGTTGYISLDEG
SNEIEIKVTDAKGDTSTYDIVITRRYGKDNVKLSNLKSTEGTLSPKFDPETYLYTVKVDRAVGRTKIVFKAQNDKATIKV
NGKEYTSAQESDYIDLKIGANLINIEVVAEDKKTTTLYRVSVIRDKIQAINEWVLSGDDWTFYDALGYQVKNKWVKYDNQ
WYFVNINGYMEKNGWLNESGEWYYLNGDGTMKTGWFKDNGYWYYLQGDGKMKNSGWGYYDKEWYMFGPNGMLETGWKQHK
GNWYFLLDNGTMRRGWQYYDLNWYYLNDDGIMKRGWLYDGKNYYYLNNSGVMKTGWQRINSKDYYFDSSGKMKTGYIFLD
GKWYNLGQDGSLN
>Mature_733_residues
MLILTVMVTGIQLGNIKSASAVELNLGFVVEAGGANLDINKSSSNAYYTDEIDMSVSTINIKSSDTSYYKLEGVTSSSSG
VKIASSTTNGITSYKIAVTKYNDFNATIKVKDLGTQEVKSYNVTFKFKEENADTFKFNKIMIVASGSGGPMTLDLDYNSD
GDDYYISGLGDDIDTAKVSIVDENGKAITSGVKITMDGKTGTFKLLGGENEILISRTVNGRTKTFKLVIAKKGSAKLKSL
TGVTLSPRFDSETTDYTATVPTATDKVVLKPTAADNSSTIRINGVLVTSGANSQPISLKEGKNDITIRVTTKDGEVGVYN
LEVTRTEAPRSSYLKYLKINSASLSPSFNKQTFDYTATVENKVTAVTITPTAEYATSTIKVNGKTVVSGGTTGYISLDEG
SNEIEIKVTDAKGDTSTYDIVITRRYGKDNVKLSNLKSTEGTLSPKFDPETYLYTVKVDRAVGRTKIVFKAQNDKATIKV
NGKEYTSAQESDYIDLKIGANLINIEVVAEDKKTTTLYRVSVIRDKIQAINEWVLSGDDWTFYDALGYQVKNKWVKYDNQ
WYFVNINGYMEKNGWLNESGEWYYLNGDGTMKTGWFKDNGYWYYLQGDGKMKNSGWGYYDKEWYMFGPNGMLETGWKQHK
GNWYFLLDNGTMRRGWQYYDLNWYYLNDDGIMKRGWLYDGKNYYYLNNSGVMKTGWQRINSKDYYFDSSGKMKTGYIFLD
GKWYNLGQDGSLN

Specific function: Cytotoxin [H]

COG id: COG5263

COG function: function code R; FOG: Glucan-binding domain (YG repeat)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 18 cell wall-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018337
- InterPro:   IPR007577
- InterPro:   IPR020974 [H]

Pfam domain/function: PF01473 CW_binding_1; PF04488 Gly_transf_sug; PF11713 Peptidase_C80 [H]

EC number: NA

Molecular weight: Translated: 81736; Mature: 81736

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILTVMVTGIQLGNIKSASAVELNLGFVVEAGGANLDINKSSSNAYYTDEIDMSVSTIN
CEEEEEEEEEEEECCCCCCCEEEEEEEEEEECCCCEEEEECCCCCCEEEEEECEEEEEEE
IKSSDTSYYKLEGVTSSSSGVKIASSTTNGITSYKIAVTKYNDFNATIKVKDLGTQEVKS
EECCCCCEEEEEEECCCCCCEEEEECCCCCEEEEEEEEEEECCCCEEEEEEECCCCHHEE
YNVTFKFKEENADTFKFNKIMIVASGSGGPMTLDLDYNSDGDDYYISGLGDDIDTAKVSI
EEEEEEECCCCCCEEEEEEEEEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEEE
VDENGKAITSGVKITMDGKTGTFKLLGGENEILISRTVNGRTKTFKLVIAKKGSAKLKSL
EECCCCEEECCEEEEECCCCCEEEEECCCCEEEEEEECCCCCEEEEEEEEECCCCCEEEE
TGVTLSPRFDSETTDYTATVPTATDKVVLKPTAADNSSTIRINGVLVTSGANSQPISLKE
ECCEECCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCEEEEC
GKNDITIRVTTKDGEVGVYNLEVTRTEAPRSSYLKYLKINSASLSPSFNKQTFDYTATVE
CCCEEEEEEEECCCCEEEEEEEEEECCCCHHHCEEEEEEECCCCCCCCCCEEEEEEEEEC
NKVTAVTITPTAEYATSTIKVNGKTVVSGGTTGYISLDEGSNEIEIKVTDAKGDTSTYDI
CCEEEEEEECCHHHCEEEEEECCEEEECCCCEEEEEECCCCCEEEEEEECCCCCCCEEEE
VITRRYGKDNVKLSNLKSTEGTLSPKFDPETYLYTVKVDRAVGRTKIVFKAQNDKATIKV
EEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCEEEEEE
NGKEYTSAQESDYIDLKIGANLINIEVVAEDKKTTTLYRVSVIRDKIQAINEWVLSGDDW
CCCEECCCCCCCEEEEEECCEEEEEEEEECCCCCEEEEEEEHHHHHHHHHHHEEECCCCE
TFYDALGYQVKNKWVKYDNQWYFVNINGYMEKNGWLNESGEWYYLNGDGTMKTGWFKDNG
EEEEECCEEEECEEEEECCEEEEEEEEEEEECCCCCCCCCCEEEECCCCEEEECEEECCC
YWYYLQGDGKMKNSGWGYYDKEWYMFGPNGMLETGWKQHKGNWYFLLDNGTMRRGWQYYD
EEEEEECCCEECCCCCCEECCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEE
LNWYYLNDDGIMKRGWLYDGKNYYYLNNSGVMKTGWQRINSKDYYFDSSGKMKTGYIFLD
EEEEEECCCCCEEECEEECCCEEEEECCCCEEECCHHHCCCCCEEECCCCCEEEEEEEEC
GKWYNLGQDGSLN
CEEEECCCCCCCC
>Mature Secondary Structure
MLILTVMVTGIQLGNIKSASAVELNLGFVVEAGGANLDINKSSSNAYYTDEIDMSVSTIN
CEEEEEEEEEEEECCCCCCCEEEEEEEEEEECCCCEEEEECCCCCCEEEEEECEEEEEEE
IKSSDTSYYKLEGVTSSSSGVKIASSTTNGITSYKIAVTKYNDFNATIKVKDLGTQEVKS
EECCCCCEEEEEEECCCCCCEEEEECCCCCEEEEEEEEEEECCCCEEEEEEECCCCHHEE
YNVTFKFKEENADTFKFNKIMIVASGSGGPMTLDLDYNSDGDDYYISGLGDDIDTAKVSI
EEEEEEECCCCCCEEEEEEEEEEEECCCCCEEEEEECCCCCCEEEEEECCCCCCCEEEEE
VDENGKAITSGVKITMDGKTGTFKLLGGENEILISRTVNGRTKTFKLVIAKKGSAKLKSL
EECCCCEEECCEEEEECCCCCEEEEECCCCEEEEEEECCCCCEEEEEEEEECCCCCEEEE
TGVTLSPRFDSETTDYTATVPTATDKVVLKPTAADNSSTIRINGVLVTSGANSQPISLKE
ECCEECCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCEEEEC
GKNDITIRVTTKDGEVGVYNLEVTRTEAPRSSYLKYLKINSASLSPSFNKQTFDYTATVE
CCCEEEEEEEECCCCEEEEEEEEEECCCCHHHCEEEEEEECCCCCCCCCCEEEEEEEEEC
NKVTAVTITPTAEYATSTIKVNGKTVVSGGTTGYISLDEGSNEIEIKVTDAKGDTSTYDI
CCEEEEEEECCHHHCEEEEEECCEEEECCCCEEEEEECCCCCEEEEEEECCCCCCCEEEE
VITRRYGKDNVKLSNLKSTEGTLSPKFDPETYLYTVKVDRAVGRTKIVFKAQNDKATIKV
EEEEECCCCCEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCEEEEEE
NGKEYTSAQESDYIDLKIGANLINIEVVAEDKKTTTLYRVSVIRDKIQAINEWVLSGDDW
CCCEECCCCCCCEEEEEECCEEEEEEEEECCCCCEEEEEEEHHHHHHHHHHHEEECCCCE
TFYDALGYQVKNKWVKYDNQWYFVNINGYMEKNGWLNESGEWYYLNGDGTMKTGWFKDNG
EEEEECCEEEECEEEEECCEEEEEEEEEEEECCCCCCCCCCEEEECCCCEEEECEEECCC
YWYYLQGDGKMKNSGWGYYDKEWYMFGPNGMLETGWKQHKGNWYFLLDNGTMRRGWQYYD
EEEEEECCCEECCCCCCEECCEEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEE
LNWYYLNDDGIMKRGWLYDGKNYYYLNNSGVMKTGWQRINSKDYYFDSSGKMKTGYIFLD
EEEEEECCCCCEEECEEECCCEEEEECCCCEEECCHHHCCCCCEEECCCCCEEEEEEEEC
GKWYNLGQDGSLN
CEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2374729; 3384474; 1603068 [H]