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The map label for this gene is gsp [C]

Identifier: 187934933

GI number: 187934933

Start: 1846527

End: 1847111

Strand: Reverse

Name: gsp [C]

Synonym: CLL_A1760

Alternate gene names: 187934933

Gene position: 1847111-1846527 (Counterclockwise)

Preceding gene: 187932431

Following gene: 187934874

Centisome position: 48.6

GC content: 28.55

Gene sequence:

>585_bases
ATGAAAAAGTTATATCGTAATCTAATTATAATTTTTACCCTACTAATCATAGTTGGTATTGGGCTCTTTGCATCACTTAA
AATTTATAGAGAAATTGAAGATAAGAAAAATGGAATAGGTCTTACTTTAGACACATATGAAGGTGTTGATGTCTATTATA
ATGGTAGCGATTATGGTAAAAGCTATAGTAATGATGGATACTATTACGGTTATAAATGGCAATGCGTAGAATATATAAAG
AGATTTTTTTATGAAGCAAAAGTCCACAAAATGCCAGATGTATATGGAAATACAAAAGATTTTTTTGACCAGGAATTGGA
ACAATGTGCATTAAATGAAAAAAGAGGATTATATCAATATAAAAATGGTGCTAATGAAAAACCTATGAAAGATGATCTTT
TAGTTTTTACATATACAAATTATGGACATGTAGTAATAATTTCAGAAGTAGGTGATAATTACATAGAGGTGGTTCAACAA
AATATGGGACAAGAATCTCGTGATAAATTTGAACTAACTTTCATAGAAAATAAATATTATGTTGGTGGCAAAAGAGAACC
TGCAGGATGGTTAAGAAAAGAATAG

Upstream 100 bases:

>100_bases
CTGTTTTATGGTAAAATAATTAGATTCATAAATAATTTAAACTTACAATTTATGAATAGATAAAATTAGAATTAGAATAT
TATCATAGAAGGCGTTTATT

Downstream 100 bases:

>100_bases
AGACAGTATATAGTTTTGTGTGAAAACAAAATTATATACTGTCTTTTTTTAATTAAAACCCTTTATTTTTAAGATCTGAC
ACTATCTCTACATATTTCTC

Product: chap domain containing protein

Products: ADP; Glutathionylspermidine; H+; Phosphate [C]

Alternate protein names: Trypanothione Synthetase Domain Protein; Amidase; Chap Domain Containing Protein; Trypanothione Synthetase Domain-Containing Protein; Chloride Channel

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKKLYRNLIIIFTLLIIVGIGLFASLKIYREIEDKKNGIGLTLDTYEGVDVYYNGSDYGKSYSNDGYYYGYKWQCVEYIK
RFFYEAKVHKMPDVYGNTKDFFDQELEQCALNEKRGLYQYKNGANEKPMKDDLLVFTYTNYGHVVIISEVGDNYIEVVQQ
NMGQESRDKFELTFIENKYYVGGKREPAGWLRKE

Sequences:

>Translated_194_residues
MKKLYRNLIIIFTLLIIVGIGLFASLKIYREIEDKKNGIGLTLDTYEGVDVYYNGSDYGKSYSNDGYYYGYKWQCVEYIK
RFFYEAKVHKMPDVYGNTKDFFDQELEQCALNEKRGLYQYKNGANEKPMKDDLLVFTYTNYGHVVIISEVGDNYIEVVQQ
NMGQESRDKFELTFIENKYYVGGKREPAGWLRKE
>Mature_194_residues
MKKLYRNLIIIFTLLIIVGIGLFASLKIYREIEDKKNGIGLTLDTYEGVDVYYNGSDYGKSYSNDGYYYGYKWQCVEYIK
RFFYEAKVHKMPDVYGNTKDFFDQELEQCALNEKRGLYQYKNGANEKPMKDDLLVFTYTNYGHVVIISEVGDNYIEVVQQ
NMGQESRDKFELTFIENKYYVGGKREPAGWLRKE

Specific function: Catalyzes The Formation Of An Amide Bond Between Glutathione And Spermidine Coupled With Hydrolysis Of ATP; Also Catalyzes The Hydrolysis Of Glutathionylspermidine To Glutathione And Spermidine. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.3.1.8; 3.5.1.78 [C]

Molecular weight: Translated: 22863; Mature: 22863

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50911 CHAP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLYRNLIIIFTLLIIVGIGLFASLKIYREIEDKKNGIGLTLDTYEGVDVYYNGSDYGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCC
SYSNDGYYYGYKWQCVEYIKRFFYEAKVHKMPDVYGNTKDFFDQELEQCALNEKRGLYQY
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHH
KNGANEKPMKDDLLVFTYTNYGHVVIISEVGDNYIEVVQQNMGQESRDKFELTFIENKYY
CCCCCCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCCCEEEEEEECEEE
VGGKREPAGWLRKE
ECCCCCCCCCCCCC
>Mature Secondary Structure
MKKLYRNLIIIFTLLIIVGIGLFASLKIYREIEDKKNGIGLTLDTYEGVDVYYNGSDYGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCCC
SYSNDGYYYGYKWQCVEYIKRFFYEAKVHKMPDVYGNTKDFFDQELEQCALNEKRGLYQY
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHH
KNGANEKPMKDDLLVFTYTNYGHVVIISEVGDNYIEVVQQNMGQESRDKFELTFIENKYY
CCCCCCCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCCCEEEEEEECEEE
VGGKREPAGWLRKE
ECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; Reduced glutathione; Spermidine [C]

Specific reaction: ATP + Reduced glutathione + Spermidine --> ADP + Glutathionylspermidine + H+ + Phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA