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The map label for this gene is ypnP [H]

Identifier: 187934867

GI number: 187934867

Start: 2704553

End: 2705890

Strand: Reverse

Name: ypnP [H]

Synonym: CLL_A2593

Alternate gene names: 187934867

Gene position: 2705890-2704553 (Counterclockwise)

Preceding gene: 187935630

Following gene: 187935696

Centisome position: 71.2

GC content: 28.62

Gene sequence:

>1338_bases
ATGATAAAAGATATGACTAAGGGGAACCCTGGAAAGATAGTGTTTTTATTTGCTATTCCTATGGTTATGGGAAATATATT
TCAGCAATTTTACAATATTATAGATTCAGTAGTTGTAGGAAATTTTATAGGAGCTAATGCATTAGCAGCTGTAGGAGCTT
CTTATCCTATTACATTTTTGTTTATAGCAATTGCAACTGGAGCTAGTATTGGATGCTCTGTTGTAATATCACAGATGTTT
GGAGCAAAACAAATAGGCAATATGAAAACAGCAATATATACATCAATTATTTCTATAGTAATTTTCAGTACGTTACTAAT
GATAATAGGAATAATTAGCAGTAATTTGGTATTAAGAATTTTAAAAACTCCACTTGATATATTAAAAGATGCTGATAGCT
ATATGAAAGTATATATGATGGGAGTAGTTTTTTTATTTGTTTATAATATTAATACTGGAGCATTTAACGCCTTAGGAAAT
TCTAAAACACCGTTATATTTTTTAATTTTTTCATCTATTTTAAATGTAGGGTTAGATTTATTATTTGTAATAAAATTTAA
TATAGGCGTAGTAGGTGCAGCATATGCAACTTTGATTTCTCAAGGTGTAGCTGCGGTATTATCATTAATATACCTTTTAA
TAAAGGTTAAAAGAATAGATGTTCATGAAGAATATAAAATATTTGATATTAATATATTGAAAAAAACATGTAAAATAGCT
ATCCCATCAATAATACAACAGGCAATAGTATCAATAGGAAATTTGTTTGTTCAAGCCTTAGTTAATACTTATGGAGTTGT
AACTATTGCTGCATATACATCAGCTACCAGAATAGATTCTATAATTATTATGCCAATGGTTAATATAAGTAGCGCAGTAT
CTACATTTACAGCTCAAAATATTGGTGCTGATTTAATAGAGCGGGTAAAGGATGGATATAAAGCAGCACTAAAAATGATA
GGTGTATTTTGTTTTATAATTGCAATCTTACTACATGTATATGCAAAAAATATAATAGGAATATTTGTTGATTCAAATAT
AAATCAAGAAGCCATTAGTATAGGAGTAGAGTATATAACAGTAGTTTCAATTTTTTATGTACTTATGGGACTTATGGTAA
CTACAAATGGAGTACTTAGGGGAGCAGGAGATATTAAAGTATTCATGATAAGCACATTGTGTAATTTATCATTAAGAGTA
ATAGCTGCATATACTTTGTCAAATCTTATTGGACAAAAGGCAATATGGTGGGCAATACCATTAGGATGGATATTAGCATC
TACAATATCTGTATCAAGATATAAGAGTGAGAGATGGAAAAATGCAAAAATGGTATGA

Upstream 100 bases:

>100_bases
TACAACAAATTCTAAAGTGTAGATTGCAATGTGTTTGAAGATTTGAAAACCATATTAAAAGAAAATGTATAATCCTAAAA
ATTATGAAAGAAGGGTTTTA

Downstream 100 bases:

>100_bases
AATATATTACATTAAATTTATGTTAAATGTAGGTAAAAAACAAAAAGTTAAAGAAATATGATATATAATCATATTTAATA
AAATAATACTTGAATTACAC

Product: mate efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MIKDMTKGNPGKIVFLFAIPMVMGNIFQQFYNIIDSVVVGNFIGANALAAVGASYPITFLFIAIATGASIGCSVVISQMF
GAKQIGNMKTAIYTSIISIVIFSTLLMIIGIISSNLVLRILKTPLDILKDADSYMKVYMMGVVFLFVYNINTGAFNALGN
SKTPLYFLIFSSILNVGLDLLFVIKFNIGVVGAAYATLISQGVAAVLSLIYLLIKVKRIDVHEEYKIFDINILKKTCKIA
IPSIIQQAIVSIGNLFVQALVNTYGVVTIAAYTSATRIDSIIIMPMVNISSAVSTFTAQNIGADLIERVKDGYKAALKMI
GVFCFIIAILLHVYAKNIIGIFVDSNINQEAISIGVEYITVVSIFYVLMGLMVTTNGVLRGAGDIKVFMISTLCNLSLRV
IAAYTLSNLIGQKAIWWAIPLGWILASTISVSRYKSERWKNAKMV

Sequences:

>Translated_445_residues
MIKDMTKGNPGKIVFLFAIPMVMGNIFQQFYNIIDSVVVGNFIGANALAAVGASYPITFLFIAIATGASIGCSVVISQMF
GAKQIGNMKTAIYTSIISIVIFSTLLMIIGIISSNLVLRILKTPLDILKDADSYMKVYMMGVVFLFVYNINTGAFNALGN
SKTPLYFLIFSSILNVGLDLLFVIKFNIGVVGAAYATLISQGVAAVLSLIYLLIKVKRIDVHEEYKIFDINILKKTCKIA
IPSIIQQAIVSIGNLFVQALVNTYGVVTIAAYTSATRIDSIIIMPMVNISSAVSTFTAQNIGADLIERVKDGYKAALKMI
GVFCFIIAILLHVYAKNIIGIFVDSNINQEAISIGVEYITVVSIFYVLMGLMVTTNGVLRGAGDIKVFMISTLCNLSLRV
IAAYTLSNLIGQKAIWWAIPLGWILASTISVSRYKSERWKNAKMV
>Mature_445_residues
MIKDMTKGNPGKIVFLFAIPMVMGNIFQQFYNIIDSVVVGNFIGANALAAVGASYPITFLFIAIATGASIGCSVVISQMF
GAKQIGNMKTAIYTSIISIVIFSTLLMIIGIISSNLVLRILKTPLDILKDADSYMKVYMMGVVFLFVYNINTGAFNALGN
SKTPLYFLIFSSILNVGLDLLFVIKFNIGVVGAAYATLISQGVAAVLSLIYLLIKVKRIDVHEEYKIFDINILKKTCKIA
IPSIIQQAIVSIGNLFVQALVNTYGVVTIAAYTSATRIDSIIIMPMVNISSAVSTFTAQNIGADLIERVKDGYKAALKMI
GVFCFIIAILLHVYAKNIIGIFVDSNINQEAISIGVEYITVVSIFYVLMGLMVTTNGVLRGAGDIKVFMISTLCNLSLRV
IAAYTLSNLIGQKAIWWAIPLGWILASTISVSRYKSERWKNAKMV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=441, Percent_Identity=21.5419501133787, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48435; Mature: 48435

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKDMTKGNPGKIVFLFAIPMVMGNIFQQFYNIIDSVVVGNFIGANALAAVGASYPITFL
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FIAIATGASIGCSVVISQMFGAKQIGNMKTAIYTSIISIVIFSTLLMIIGIISSNLVLRI
HHHHHCCCCHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKTPLDILKDADSYMKVYMMGVVFLFVYNINTGAFNALGNSKTPLYFLIFSSILNVGLDL
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHH
LFVIKFNIGVVGAAYATLISQGVAAVLSLIYLLIKVKRIDVHEEYKIFDINILKKTCKIA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHH
IPSIIQQAIVSIGNLFVQALVNTYGVVTIAAYTSATRIDSIIIMPMVNISSAVSTFTAQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHEEEEEHHHHHHHHHHHHHHH
IGADLIERVKDGYKAALKMIGVFCFIIAILLHVYAKNIIGIFVDSNINQEAISIGVEYIT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHH
VVSIFYVLMGLMVTTNGVLRGAGDIKVFMISTLCNLSLRVIAAYTLSNLIGQKAIWWAIP
HHHHHHHHHHHHHHCCCCEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LGWILASTISVSRYKSERWKNAKMV
HHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIKDMTKGNPGKIVFLFAIPMVMGNIFQQFYNIIDSVVVGNFIGANALAAVGASYPITFL
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FIAIATGASIGCSVVISQMFGAKQIGNMKTAIYTSIISIVIFSTLLMIIGIISSNLVLRI
HHHHHCCCCHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKTPLDILKDADSYMKVYMMGVVFLFVYNINTGAFNALGNSKTPLYFLIFSSILNVGLDL
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHH
LFVIKFNIGVVGAAYATLISQGVAAVLSLIYLLIKVKRIDVHEEYKIFDINILKKTCKIA
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHH
IPSIIQQAIVSIGNLFVQALVNTYGVVTIAAYTSATRIDSIIIMPMVNISSAVSTFTAQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHEEEEEHHHHHHHHHHHHHHH
IGADLIERVKDGYKAALKMIGVFCFIIAILLHVYAKNIIGIFVDSNINQEAISIGVEYIT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHH
VVSIFYVLMGLMVTTNGVLRGAGDIKVFMISTLCNLSLRVIAAYTLSNLIGQKAIWWAIP
HHHHHHHHHHHHHHCCCCEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LGWILASTISVSRYKSERWKNAKMV
HHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]