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The map label for this gene is lytB [H]

Identifier: 187934177

GI number: 187934177

Start: 3367670

End: 3369016

Strand: Reverse

Name: lytB [H]

Synonym: CLL_A3225

Alternate gene names: 187934177

Gene position: 3369016-3367670 (Counterclockwise)

Preceding gene: 187933855

Following gene: 187935050

Centisome position: 88.65

GC content: 30.22

Gene sequence:

>1347_bases
ATGAATAAAAGATTAAAACATATAATCGCAGCTACTCTTGTAGTAAGTGCATTTACAACTATTACTCCAGCAAAATATAT
TAATTTAGGAGCAGTAAATGCTTATGCATCAAGTAATAGCATGAGTAAAGATGAATTTGATGATCTTGTTGTATGCAAGG
GTTCAAGCTCAAAGGAGTTACAACTTTATAGTTCTTCAAGTTGCAAGGATTCTGATGAGATTGATTTTAAATTTGGTACT
AAGACATATTATGTTAAGATTTCAGGTAGTACAAATTCTGTAACTATTGATGCAGAAGTTGATAGTGATTATGAAGCACA
TGTATTTAAAGGAAATAAGGACAAGGCATATGATTTGGGAGAAGAAGTTAAAGTCGGTTCAGGAACAACCACTCTTTATG
TAAGAATATATGAAGATGGAGAATTTGATGAGGATGATGTTGAAGAAGATGTAGCAAGAACTTATAAGATATGTGTAAAA
AATGGCTCTAGTTCTGATGATGAGGATAGTGATTCTGATAAGGTTTATTTAAAAGACCTAACTTTAAGTGATGGTGATAT
AAATTTTAGTAAGCAAAAGACTTCTTATGATATAAATGTTAATGAATCAGTGAATTCCATTATGATTAAAGCTGTACCTA
AAAATGATGATGATTACACTGTTGAAATTGATGGTGATACAGTTGATGATGGAGATAAGTATAAAAAAGAAGTGGATCTT
AAAAAAGGAAAAAATACTATTAAAATAAATATAGAAGATAACGATGATAATAAAAGAACTTATACTTTAAACATTACTAG
AGGGGTGACATCTATTTCTGGTAATCAATCAACAAGTAACAATACAAATAATAATAAGCAGGATTCTAACACAGTAAAAC
CTAGTACACCAACAGATTCTAATAAGAAGTGTGATCAATGGGTAGATGCTAATGGAAGATGGCAATATAATGACTCAAAT
GGAAATGCTCTTAAGAGTAGATGGCATAGTGATAAATCTTCTGGTAAATGGTATTACTTAGATGAAAATGGATATATGAA
AACAGGTTGGTTAAAAGATGGAGAGTCATGGTATTATTTAGATGATAATGGTGCTATGAAAACAGGATGGTTACTTTGTG
GAAGTGACTGGTATTATTTAAATAGTAATGGCTCTATGCATACAGGTTGGTTACAAAGTGGATCAAATTGGTACTTTATT
AACAAAAATACTGGTGTAATGAAGAATAATGGTTGGATTGTAGATAATGGAAAATATTATTATTTTAGTTCATCAGGAAT
GATGTTGTCTAATGTTACAATAAATGGATATATATTAGGAAAAGATGGGGCTTGGATAGGAAGATAA

Upstream 100 bases:

>100_bases
TGGTGATAGTCGCTAATAGGTAAATGGTGACTGTTACCATTTTTTTTGGTATAATAGTCCAAAAGGATAATTATGGAAAA
GTAATTAGGGGGATTGAATT

Downstream 100 bases:

>100_bases
TAAAAAAGTACCCAAAATTTGTTTTTTAATTGTATTTTTTATTGAGTATAAGTTGTAACAAAAGAATTAAGAATATCTTA
AGCTTAAATTAATTTACTTG

Product: collagenolytic protease

Products: NA

Alternate protein names: Murein hydrolase [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MNKRLKHIIAATLVVSAFTTITPAKYINLGAVNAYASSNSMSKDEFDDLVVCKGSSSKELQLYSSSSCKDSDEIDFKFGT
KTYYVKISGSTNSVTIDAEVDSDYEAHVFKGNKDKAYDLGEEVKVGSGTTTLYVRIYEDGEFDEDDVEEDVARTYKICVK
NGSSSDDEDSDSDKVYLKDLTLSDGDINFSKQKTSYDINVNESVNSIMIKAVPKNDDDYTVEIDGDTVDDGDKYKKEVDL
KKGKNTIKINIEDNDDNKRTYTLNITRGVTSISGNQSTSNNTNNNKQDSNTVKPSTPTDSNKKCDQWVDANGRWQYNDSN
GNALKSRWHSDKSSGKWYYLDENGYMKTGWLKDGESWYYLDDNGAMKTGWLLCGSDWYYLNSNGSMHTGWLQSGSNWYFI
NKNTGVMKNNGWIVDNGKYYYFSSSGMMLSNVTINGYILGKDGAWIGR

Sequences:

>Translated_448_residues
MNKRLKHIIAATLVVSAFTTITPAKYINLGAVNAYASSNSMSKDEFDDLVVCKGSSSKELQLYSSSSCKDSDEIDFKFGT
KTYYVKISGSTNSVTIDAEVDSDYEAHVFKGNKDKAYDLGEEVKVGSGTTTLYVRIYEDGEFDEDDVEEDVARTYKICVK
NGSSSDDEDSDSDKVYLKDLTLSDGDINFSKQKTSYDINVNESVNSIMIKAVPKNDDDYTVEIDGDTVDDGDKYKKEVDL
KKGKNTIKINIEDNDDNKRTYTLNITRGVTSISGNQSTSNNTNNNKQDSNTVKPSTPTDSNKKCDQWVDANGRWQYNDSN
GNALKSRWHSDKSSGKWYYLDENGYMKTGWLKDGESWYYLDDNGAMKTGWLLCGSDWYYLNSNGSMHTGWLQSGSNWYFI
NKNTGVMKNNGWIVDNGKYYYFSSSGMMLSNVTINGYILGKDGAWIGR
>Mature_448_residues
MNKRLKHIIAATLVVSAFTTITPAKYINLGAVNAYASSNSMSKDEFDDLVVCKGSSSKELQLYSSSSCKDSDEIDFKFGT
KTYYVKISGSTNSVTIDAEVDSDYEAHVFKGNKDKAYDLGEEVKVGSGTTTLYVRIYEDGEFDEDDVEEDVARTYKICVK
NGSSSDDEDSDSDKVYLKDLTLSDGDINFSKQKTSYDINVNESVNSIMIKAVPKNDDDYTVEIDGDTVDDGDKYKKEVDL
KKGKNTIKINIEDNDDNKRTYTLNITRGVTSISGNQSTSNNTNNNKQDSNTVKPSTPTDSNKKCDQWVDANGRWQYNDSN
GNALKSRWHSDKSSGKWYYLDENGYMKTGWLKDGESWYYLDDNGAMKTGWLLCGSDWYYLNSNGSMHTGWLQSGSNWYFI
NKNTGVMKNNGWIVDNGKYYYFSSSGMMLSNVTINGYILGKDGAWIGR

Specific function: Plays an important role in cell wall degradation and cell separation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 15 cell wall-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018337
- InterPro:   IPR013338
- InterPro:   IPR002901 [H]

Pfam domain/function: PF01473 CW_binding_1; PF01832 Glucosaminidase [H]

EC number: =3.2.1.96 [H]

Molecular weight: Translated: 50225; Mature: 50225

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRLKHIIAATLVVSAFTTITPAKYINLGAVNAYASSNSMSKDEFDDLVVCKGSSSKEL
CCHHHHHHHHHHHHHHHHHHCCCHHEEEEEEEEEECCCCCCCCCCCCCEEEECCCCCCEE
QLYSSSSCKDSDEIDFKFGTKTYYVKISGSTNSVTIDAEVDSDYEAHVFKGNKDKAYDLG
EEEECCCCCCCCCEEEEECCEEEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCCCC
EEVKVGSGTTTLYVRIYEDGEFDEDDVEEDVARTYKICVKNGSSSDDEDSDSDKVYLKDL
CEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHEEEEEEECCCCCCCCCCCCCEEEEEEE
TLSDGDINFSKQKTSYDINVNESVNSIMIKAVPKNDDDYTVEIDGDTVDDGDKYKKEVDL
EECCCCCEECCCCEEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHH
KKGKNTIKINIEDNDDNKRTYTLNITRGVTSISGNQSTSNNTNNNKQDSNTVKPSTPTDS
HCCCCEEEEEEECCCCCCEEEEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
NKKCDQWVDANGRWQYNDSNGNALKSRWHSDKSSGKWYYLDENGYMKTGWLKDGESWYYL
CCCCHHHCCCCCEEEEECCCCCHHHHHHCCCCCCCCEEEECCCCEEEECEEECCCEEEEE
DDNGAMKTGWLLCGSDWYYLNSNGSMHTGWLQSGSNWYFINKNTGVMKNNGWIVDNGKYY
CCCCCEEEEEEEECCCEEEECCCCCEEEEEEECCCCEEEEECCCCEEECCCEEEECCEEE
YFSSSGMMLSNVTINGYILGKDGAWIGR
EEECCCEEEEEEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MNKRLKHIIAATLVVSAFTTITPAKYINLGAVNAYASSNSMSKDEFDDLVVCKGSSSKEL
CCHHHHHHHHHHHHHHHHHHCCCHHEEEEEEEEEECCCCCCCCCCCCCEEEECCCCCCEE
QLYSSSSCKDSDEIDFKFGTKTYYVKISGSTNSVTIDAEVDSDYEAHVFKGNKDKAYDLG
EEEECCCCCCCCCEEEEECCEEEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCCCC
EEVKVGSGTTTLYVRIYEDGEFDEDDVEEDVARTYKICVKNGSSSDDEDSDSDKVYLKDL
CEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHEEEEEEECCCCCCCCCCCCCEEEEEEE
TLSDGDINFSKQKTSYDINVNESVNSIMIKAVPKNDDDYTVEIDGDTVDDGDKYKKEVDL
EECCCCCEECCCCEEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHH
KKGKNTIKINIEDNDDNKRTYTLNITRGVTSISGNQSTSNNTNNNKQDSNTVKPSTPTDS
HCCCCEEEEEEECCCCCCEEEEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
NKKCDQWVDANGRWQYNDSNGNALKSRWHSDKSSGKWYYLDENGYMKTGWLKDGESWYYL
CCCCHHHCCCCCEEEEECCCCCHHHHHHCCCCCCCCEEEECCCCEEEECEEECCCEEEEE
DDNGAMKTGWLLCGSDWYYLNSNGSMHTGWLQSGSNWYFINKNTGVMKNNGWIVDNGKYY
CCCCCEEEEEEEECCCEEEECCCCCEEEEEEECCCCEEEEECCCCEEECCCEEEECCEEE
YFSSSGMMLSNVTINGYILGKDGAWIGR
EEECCCEEEEEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10096093; 11544234 [H]