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The map label for this gene is yniC [H]

Identifier: 187934002

GI number: 187934002

Start: 1969162

End: 1969815

Strand: Reverse

Name: yniC [H]

Synonym: CLL_A1868

Alternate gene names: 187934002

Gene position: 1969815-1969162 (Counterclockwise)

Preceding gene: 187934133

Following gene: 187933837

Centisome position: 51.83

GC content: 29.2

Gene sequence:

>654_bases
GTGAGAGCATTTATATTTGATATGGACGGTGTAATAATAGATAGTGAACCAATACATCGTCAGGTGCATGGAGAAATTAT
GAATACTTTAGGAATAAATATATCTAAGGGAGAATTAGCATTATATGCAGGCGCTACAAATGAATATATTTTTACAAAAT
TAAAAGAAAGATATGGAATAAAGAAATCTGTTAGTGAACTTATGGATTGTAAATCTAAACTTATTATTAACAAAGTAAAA
GAAGAGTCACTAGAACCTATAAATGGAATTAGGGAATTATTAGATGCTTTAAGAAAAAATAATATAAAGACAGCTATAGG
ATCATCATCTCCTAGAAGTTTAATAGAGGCTGTTATAGATAAGTTTAATCTACACGGTGCTTTTGATTGTATAGTAAGTG
GAGAAGAAGTTGAAAGAAGTAAACCATATCCTGATGTTTACATAGAAGTAAGCAAAAAGTTGGGCATAAATCCAGAAAAG
TGCATAGTGGTTGAAGATTCTCATAATGGTGTACAAGCTGCTAAAAGTGCTGGAATGAAATGTATAGGTTTTGATAATGT
AAATTCAGGTAATCAAGATTTATCGAAAGCTGATGTTAGAGTAGATACTATAAGAAAAATAGATATATTTAATTTATGTA
AATATTTTGGTTAG

Upstream 100 bases:

>100_bases
TGAGGGAGATAAACAAGAATGATTTTGAAATATAAATGCGTAATAATTTCCAGTTGTGTTATAATTGATGAAACAAATAG
AATAAAGGGTGTGTTAAGCT

Downstream 100 bases:

>100_bases
GATAGAATTAAAGATTATTATTTTAAAGTTTATTATTGATAAACTTTAAAATAATATGAAAATATATAAATTTCAGAAAA
AAGGAAGGTATTTTTGTGAG

Product: HAD-superfamily hydrolase subfamily IA, variant 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MRAFIFDMDGVIIDSEPIHRQVHGEIMNTLGINISKGELALYAGATNEYIFTKLKERYGIKKSVSELMDCKSKLIINKVK
EESLEPINGIRELLDALRKNNIKTAIGSSSPRSLIEAVIDKFNLHGAFDCIVSGEEVERSKPYPDVYIEVSKKLGINPEK
CIVVEDSHNGVQAAKSAGMKCIGFDNVNSGNQDLSKADVRVDTIRKIDIFNLCKYFG

Sequences:

>Translated_217_residues
MRAFIFDMDGVIIDSEPIHRQVHGEIMNTLGINISKGELALYAGATNEYIFTKLKERYGIKKSVSELMDCKSKLIINKVK
EESLEPINGIRELLDALRKNNIKTAIGSSSPRSLIEAVIDKFNLHGAFDCIVSGEEVERSKPYPDVYIEVSKKLGINPEK
CIVVEDSHNGVQAAKSAGMKCIGFDNVNSGNQDLSKADVRVDTIRKIDIFNLCKYFG
>Mature_217_residues
MRAFIFDMDGVIIDSEPIHRQVHGEIMNTLGINISKGELALYAGATNEYIFTKLKERYGIKKSVSELMDCKSKLIINKVK
EESLEPINGIRELLDALRKNNIKTAIGSSSPRSLIEAVIDKFNLHGAFDCIVSGEEVERSKPYPDVYIEVSKKLGINPEK
CIVVEDSHNGVQAAKSAGMKCIGFDNVNSGNQDLSKADVRVDTIRKIDIFNLCKYFG

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates 2-deoxyglucose 6-phosphate and mannose 6- phosphate [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=224, Percent_Identity=29.4642857142857, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1788021, Length=211, Percent_Identity=29.3838862559242, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789046, Length=181, Percent_Identity=28.1767955801105, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787576, Length=200, Percent_Identity=25.5, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789787, Length=229, Percent_Identity=23.5807860262009, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790151, Length=186, Percent_Identity=26.8817204301075, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082080, Length=211, Percent_Identity=27.0142180094787, Blast_Score=63, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116008157, Length=199, Percent_Identity=25.6281407035176, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI20129151, Length=224, Percent_Identity=25.8928571428571, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI17137324, Length=199, Percent_Identity=25.6281407035176, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24128; Mature: 24128

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAFIFDMDGVIIDSEPIHRQVHGEIMNTLGINISKGELALYAGATNEYIFTKLKERYGI
CCEEEEECCCEEECCCHHHHHHHHHHHHHHCCEECCCCEEEEECCCCHHHHHHHHHHHCH
KKSVSELMDCKSKLIINKVKEESLEPINGIRELLDALRKNNIKTAIGSSSPRSLIEAVID
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHH
KFNLHGAFDCIVSGEEVERSKPYPDVYIEVSKKLGINPEKCIVVEDSHNGVQAAKSAGMK
HHCCCCCEEEEECCCHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHCCCE
CIGFDNVNSGNQDLSKADVRVDTIRKIDIFNLCKYFG
EEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRAFIFDMDGVIIDSEPIHRQVHGEIMNTLGINISKGELALYAGATNEYIFTKLKERYGI
CCEEEEECCCEEECCCHHHHHHHHHHHHHHCCEECCCCEEEEECCCCHHHHHHHHHHHCH
KKSVSELMDCKSKLIINKVKEESLEPINGIRELLDALRKNNIKTAIGSSSPRSLIEAVID
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHH
KFNLHGAFDCIVSGEEVERSKPYPDVYIEVSKKLGINPEKCIVVEDSHNGVQAAKSAGMK
HHCCCCCEEEEECCCHHHCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCHHHHHHCCCE
CIGFDNVNSGNQDLSKADVRVDTIRKIDIFNLCKYFG
EEECCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]